메뉴 건너뛰기




Volumn 5, Issue , 2015, Pages e541-

LPA signaling initiates schizophrenia-like brain and behavioral changes in a mouse model of prenatal brain hemorrhage

Author keywords

[No Author keywords available]

Indexed keywords

AMPHETAMINE; LYSOPHOSPHATIDIC ACID; PARVALBUMIN; TYROSINE 3 MONOOXYGENASE; LYSOPHOSPHOLIPID;

EID: 84926312321     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2015.33     Document Type: Article
Times cited : (36)

References (74)
  • 1
    • 22144432283 scopus 로고    scopus 로고
    • A systematic review of the prevalence of schizophrenia
    • Saha S, Chant D, Welham J, McGrath J. A systematic review of the prevalence of schizophrenia. PLoS Med 2005; 2: e141.
    • (2005) PLoS Med , vol.2 , pp. e141
    • Saha, S.1    Chant, D.2    Welham, J.3    McGrath, J.4
  • 2
    • 36049009089 scopus 로고    scopus 로고
    • Obstetric conditions and risk of first admission with schizophrenia: A Danish national register based study
    • Byrne M, Agerbo E, Bennedsen B, Eaton WW, Mortensen PB. Obstetric conditions and risk of first admission with schizophrenia: a Danish national register based study. Schizophr Res 2007; 97: 51-59.
    • (2007) Schizophr Res , vol.97 , pp. 51-59
    • Byrne, M.1    Agerbo, E.2    Bennedsen, B.3    Eaton, W.W.4    Mortensen, P.B.5
  • 3
    • 77952316808 scopus 로고    scopus 로고
    • Perinatal risk and psychiatric outcome in adolescents born preterm with very low birth weight or term small for gestational age
    • Indredavik MS, Vik T, Evensen KA, Skranes J, Taraldsen G, Brubakk AM. Perinatal risk and psychiatric outcome in adolescents born preterm with very low birth weight or term small for gestational age. J Dev Behav Pediatr 2010; 31: 286-294.
    • (2010) J Dev Behav Pediatr , vol.31 , pp. 286-294
    • Indredavik, M.S.1    Vik, T.2    Evensen, K.A.3    Skranes, J.4    Taraldsen, G.5    Brubakk, A.M.6
  • 4
    • 84875117385 scopus 로고    scopus 로고
    • Modifiable risk factors for schizophrenia and autism-shared risk factors impacting on brain development
    • Hamlyn J, Duhig M, McGrath J, Scott J. Modifiable risk factors for schizophrenia and autism-shared risk factors impacting on brain development. Neurobiol Dis 2013; 53: 3-9.
    • (2013) Neurobiol Dis , vol.53 , pp. 3-9
    • Hamlyn, J.1    Duhig, M.2    McGrath, J.3    Scott, J.4
  • 5
    • 0036303358 scopus 로고    scopus 로고
    • Obstetric complications and schizophrenia: Historical and meta-analytic review
    • Cannon M, Jones PB, Murray RM. Obstetric complications and schizophrenia: historical and meta-analytic review. Am J Psychiatry 2002; 159: 1080-1092.
    • (2002) Am J Psychiatry , vol.159 , pp. 1080-1092
    • Cannon, M.1    Jones, P.B.2    Murray, R.M.3
  • 6
    • 0033550741 scopus 로고    scopus 로고
    • Prenatal and perinatal risk factors for schizophrenia, affective psychosis, and reactive psychosis of early onset: Case-control study
    • Hultman CM, Sparén P, Takei N, Murray RM, Cnattingius S. Prenatal and perinatal risk factors for schizophrenia, affective psychosis, and reactive psychosis of early onset: case-control study. BMJ 1999; 318: 421-426.
    • (1999) BMJ , vol.318 , pp. 421-426
    • Hultman, C.M.1    Sparén, P.2    Takei, N.3    Murray, R.M.4    Cnattingius, S.5
  • 7
    • 2442505571 scopus 로고    scopus 로고
    • Obstetrical complications and subsequent schizophrenia in adolescent and young adult offsprings: Is there a relationship?
    • Boog G. Obstetrical complications and subsequent schizophrenia in adolescent and young adult offsprings: is there a relationship? Eur J Obstet Gynecol Reprod Biol 2004; 114: 130-136.
    • (2004) Eur J Obstet Gynecol Reprod Biol , vol.114 , pp. 130-136
    • Boog, G.1
  • 8
    • 0001418839 scopus 로고
    • The etiology of so-called schizophrenic psychoses, with special reference to their occurrence in twins
    • Rosanoff AJ, Handy LM, Plesset IR, Brush S. The etiology of so-called schizophrenic psychoses, with special reference to their occurrence in twins. Am J Psychiatry 1934; 91: 247-286.
    • (1934) Am J Psychiatry , vol.91 , pp. 247-286
    • Rosanoff, A.J.1    Handy, L.M.2    Plesset, I.R.3    Brush, S.4
  • 9
    • 0016746133 scopus 로고
    • Early childhood psychosis and bleeding during pregnancy. A prospective study of gravid women and their offspring
    • Torrey EF, Hersh SP, McCabe KD. Early childhood psychosis and bleeding during pregnancy. A prospective study of gravid women and their offspring. J Autism Child Schizophr 1975; 5: 287-297.
    • (1975) J Autism Child Schizophr , vol.5 , pp. 287-297
    • Torrey, E.F.1    Hersh, S.P.2    McCabe, K.D.3
  • 10
    • 84892609862 scopus 로고    scopus 로고
    • Prenatal Poly(I:C) exposure and other developmental immune activation models in rodent systems
    • Meyer U. Prenatal Poly(I:C) exposure and other developmental immune activation models in rodent systems. Biol Psychiatry 2014; 75: 307-315.
    • (2014) Biol Psychiatry , vol.75 , pp. 307-315
    • Meyer, U.1
  • 11
    • 0027232391 scopus 로고
    • The bioactive phospholipid lysophosphatidic acid is released from activated platelets
    • Eichholtz T, Jalink K, Fahrenfort I, Moolenaar WH. The bioactive phospholipid lysophosphatidic acid is released from activated platelets. Biochem J 1993; 291: 677-680.
    • (1993) Biochem J , vol.291 , pp. 677-680
    • Eichholtz, T.1    Jalink, K.2    Fahrenfort, I.3    Moolenaar, W.H.4
  • 12
    • 4644335035 scopus 로고    scopus 로고
    • Protein kinase Cdelta mediates lysophosphatidic acid-induced NF-kB activation and interleukin-8 secretion in human bronchial epithelial cells
    • Cummings R, Zhao Y, Jacoby D, Spannhake EW, Ohba M, Garcia JG et al. Protein kinase Cdelta mediates lysophosphatidic acid-induced NF-kB activation and interleukin-8 secretion in human bronchial epithelial cells. J Biol Chem 2004; 279: 41085-41094.
    • (2004) J Biol Chem , vol.279 , pp. 41085-41094
    • Cummings, R.1    Zhao, Y.2    Jacoby, D.3    Spannhake, E.W.4    Ohba, M.5    Garcia, J.G.6
  • 13
    • 80054122623 scopus 로고    scopus 로고
    • Lysophosphatidic acid level and the incidence of silent brain infarction in patients with nonvalvular atrial fibrillation
    • Li ZG, Yu ZC, Yu YP, Ju WP, Wang DZ, Zhan X et al. Lysophosphatidic acid level and the incidence of silent brain infarction in patients with nonvalvular atrial fibrillation. Int J Mol Sci 2010; 11: 3988-3998.
    • (2010) Int J Mol Sci , vol.11 , pp. 3988-3998
    • Li, Z.G.1    Yu, Z.C.2    Yu, Y.P.3    Ju, W.P.4    Wang, D.Z.5    Zhan, X.6
  • 15
    • 84886531537 scopus 로고    scopus 로고
    • Lysophosphatidic acid (LPA) receptor signaling
    • Chun, J, Hla, T, Spiegel, S, Moolenaar, W (eds). John Wiley & Sons: Hoboken, NJ, USA
    • Mirendil H Lin M-E Chun J. Lysophosphatidic acid (LPA) receptor signaling. Chun, J, Hla, T, Spiegel, S, Moolenaar, W (eds). Lysophospholipid Receptors: Signaling and Biochemistry. John Wiley & Sons: Hoboken, NJ, USA, 2013. 1-39.
    • (2013) Lysophospholipid Receptors: Signaling and Biochemistry , pp. 1-39
    • Mirendil, H.1    Lin, M.-E.2    Chun, J.3
  • 17
    • 0037073806 scopus 로고    scopus 로고
    • Serum lysophosphatidic acid is produced through diverse phospholipase pathways
    • Aoki J, Taira A, Takanezawa Y, Kishi Y, Hama K, Kishimoto T et al. Serum lysophosphatidic acid is produced through diverse phospholipase pathways. J Biol Chem 2002; 277: 48737-48744.
    • (2002) J Biol Chem , vol.277 , pp. 48737-48744
    • Aoki, J.1    Taira, A.2    Takanezawa, Y.3    Kishi, Y.4    Hama, K.5    Kishimoto, T.6
  • 18
    • 65349145784 scopus 로고    scopus 로고
    • Lysophosphatidic acid induces alphavbeta6 integrin-mediated TGF-beta activation via the LPA2 receptor and the small G protein G alpha(q)
    • Xu MY, Porte J, Knox AJ, Weinreb PH, Maher TM, Violette SM et al. Lysophosphatidic acid induces alphavbeta6 integrin-mediated TGF-beta activation via the LPA2 receptor and the small G protein G alpha(q). Am J Pathol 2009; 174: 1264-1279.
    • (2009) Am J Pathol , vol.174 , pp. 1264-1279
    • Xu, M.Y.1    Porte, J.2    Knox, A.J.3    Weinreb, P.H.4    Maher, T.M.5    Violette, S.M.6
  • 19
    • 77749291794 scopus 로고    scopus 로고
    • LPA induces IL-6 secretion from aortic smooth muscle cells via an LPA1-regulated, PKC-dependent, and p38alpha-mediated pathway
    • Hao F, Tan M, Wu DD, Xu X, Cui MZ. LPA induces IL-6 secretion from aortic smooth muscle cells via an LPA1-regulated, PKC-dependent, and p38alpha-mediated pathway. Am J Physiol Heart Circ Physiol 2010; 298: H974-H983.
    • (2010) Am J Physiol Heart Circ Physiol , vol.298 , pp. H974-H983
    • Hao, F.1    Tan, M.2    Wu, D.D.3    Xu, X.4    Cui, M.Z.5
  • 20
    • 77953036199 scopus 로고    scopus 로고
    • Diversity of lysophosphatidic acid receptormediated intracellular calcium signaling in early cortical neurogenesis
    • Dubin A. E, Herr D. R, Chun J. Diversity of lysophosphatidic acid receptormediated intracellular calcium signaling in early cortical neurogenesis. J Neurosci 2010; 30: 7300-7309.
    • (2010) J Neurosci , vol.30 , pp. 7300-7309
    • Dubin, A.E.1    Herr, D.R.2    Chun, J.3
  • 21
    • 75349096497 scopus 로고    scopus 로고
    • A longitudinal examination of the neurodevelopmental impact of prenatal immune activation in mice reveals primary defects in dopaminergic development relevant to schizophrenia
    • Vuillermot S, Weber L, Feldon J, Meyer U. A longitudinal examination of the neurodevelopmental impact of prenatal immune activation in mice reveals primary defects in dopaminergic development relevant to schizophrenia. J Neurosci 2010; 30: 1270-1287.
    • (2010) J Neurosci , vol.30 , pp. 1270-1287
    • Vuillermot, S.1    Weber, L.2    Feldon, J.3    Meyer, U.4
  • 22
    • 35148872226 scopus 로고    scopus 로고
    • Maternal immune activation alters fetal brain development through interleukin-6
    • Smith SEP, Li J, Garbett K, Mirnics K, Patterson PH. Maternal immune activation alters fetal brain development through interleukin-6. J Neurosci 2007; 27: 10695-10702.
    • (2007) J Neurosci , vol.27 , pp. 10695-10702
    • Smith, S.E.P.1    Li, J.2    Garbett, K.3    Mirnics, K.4    Patterson, P.H.5
  • 23
    • 81255209206 scopus 로고    scopus 로고
    • Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse
    • Kuroda K, Yamada S, Tanaka M, Iizuka M, Yano H, Mori D et al. Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse. Hum Mol Genet 2011; 20: 4666-4683.
    • (2011) Hum Mol Genet , vol.20 , pp. 4666-4683
    • Kuroda, K.1    Yamada, S.2    Tanaka, M.3    Iizuka, M.4    Yano, H.5    Mori, D.6
  • 25
    • 69249221567 scopus 로고    scopus 로고
    • Mice mutant for genes associated with schizophrenia: Common phenotype or distinct endophenotypes?
    • Desbonnet L, Waddington JL, O'Tuathaigh CMP. Mice mutant for genes associated with schizophrenia: common phenotype or distinct endophenotypes? Behav Brain Res 2009; 204: 258-273.
    • (2009) Behav Brain Res , vol.204 , pp. 258-273
    • Desbonnet, L.1    Waddington, J.L.2    O'Tuathaigh, C.M.P.3
  • 26
    • 77954218028 scopus 로고    scopus 로고
    • Effects of prenatal infection on brain development and behavior: A review of findings from animal models
    • Boksa P. Effects of prenatal infection on brain development and behavior: a review of findings from animal models. Brain Behav Immun 2010; 24: 881-897.
    • (2010) Brain Behav Immun , vol.24 , pp. 881-897
    • Boksa, P.1
  • 27
    • 84866754819 scopus 로고    scopus 로고
    • Sex effects on neurodevelopmental outcomes of innate immune activation during prenatal and neonatal life
    • Rana SA, Aavani T, Pittman QJ. Sex effects on neurodevelopmental outcomes of innate immune activation during prenatal and neonatal life. Horm Behav 2012; 62: 228-236.
    • (2012) Horm Behav , vol.62 , pp. 228-236
    • Rana, S.A.1    Aavani, T.2    Pittman, Q.J.3
  • 28
    • 84876967933 scopus 로고    scopus 로고
    • Gender differences in schizophrenia and first-episode psychosis: A comprehensive literature review
    • Ochoa S, Usall J, Cobo J, Labad X, Kulkarni J. Gender differences in schizophrenia and first-episode psychosis: a comprehensive literature review. Schizophr Res Treatment 2012; 2012: 916198.
    • (2012) Schizophr Res Treatment , vol.2012 , pp. 916198
    • Ochoa, S.1    Usall, J.2    Cobo, J.3    Labad, X.4    Kulkarni, J.5
  • 29
    • 55549114728 scopus 로고    scopus 로고
    • Expression patterns of the lysophospholipid receptor genes during mouse early development
    • Ohuchi H, Hamada A, Matsuda H, Takagi A, Tanaka M, Aoki J et al. Expression patterns of the lysophospholipid receptor genes during mouse early development. Dev Dyn 2008; 237: 3280-3294.
    • (2008) Dev Dyn , vol.237 , pp. 3280-3294
    • Ohuchi, H.1    Hamada, A.2    Matsuda, H.3    Takagi, A.4    Tanaka, M.5    Aoki, J.6
  • 30
    • 0141570981 scopus 로고    scopus 로고
    • Ki16425, a subtype-selective antagonist for EDG-family lysophosphatidic acid receptors
    • Ohta H, Sato K, Murata N, Damirin A, Malchinkhuu E, Kon J et al. Ki16425, a subtype-selective antagonist for EDG-family lysophosphatidic acid receptors. Mol Pharmacol 2003; 64: 994-1005.
    • (2003) Mol Pharmacol , vol.64 , pp. 994-1005
    • Ohta, H.1    Sato, K.2    Murata, N.3    Damirin, A.4    Malchinkhuu, E.5    Kon, J.6
  • 34
    • 2442679391 scopus 로고    scopus 로고
    • The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors
    • Graler MH, Goetzl EJ. The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors. FASEB J 2004; 18: 551-553.
    • (2004) FASEB J , vol.18 , pp. 551-553
    • Graler, M.H.1    Goetzl, E.J.2
  • 35
    • 79957925060 scopus 로고    scopus 로고
    • Engagement of S1P (1)-degradative mechanisms leads to vascular leak in mice
    • Oo ML, Chang SH, Thangada S, Wu MT, Rezaul K, Blaho V et al. Engagement of S1P (1)-degradative mechanisms leads to vascular leak in mice. J Clin Invest 2011; 121: 2290-2300.
    • (2011) J Clin Invest , vol.121 , pp. 2290-2300
    • Oo, M.L.1    Chang, S.H.2    Thangada, S.3    Wu, M.T.4    Rezaul, K.5    Blaho, V.6
  • 36
    • 79551674537 scopus 로고    scopus 로고
    • FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation
    • Choi JW, Gardell SE, Herr DR, Rivera R, Lee CW, Noguchi K et al. FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation. Proc Natl Acad Sci USA 2011; 108: 751-756.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 751-756
    • Choi, J.W.1    Gardell, S.E.2    Herr, D.R.3    Rivera, R.4    Lee, C.W.5    Noguchi, K.6
  • 37
    • 34247874512 scopus 로고    scopus 로고
    • Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor
    • Oo ML, Thangada S, Wu MT, Liu CH, Macdonald TL, Lynch KR et al. Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor. J Biol Chem 2007; 282: 9082-9089.
    • (2007) J Biol Chem , vol.282 , pp. 9082-9089
    • Oo, M.L.1    Thangada, S.2    Wu, M.T.3    Liu, C.H.4    MacDonald, T.L.5    Lynch, K.R.6
  • 39
    • 46249104490 scopus 로고    scopus 로고
    • Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: The SzGene database
    • Allen N, Bagade S, McQueen MB, Ioannidis JP, Kavvoura FK, Khoury MJ et al. Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nat Genet 2008; 4: 827-834.
    • (2008) Nat Genet , vol.4 , pp. 827-834
    • Allen, N.1    Bagade, S.2    McQueen, M.B.3    Ioannidis, J.P.4    Kavvoura, F.K.5    Khoury, M.J.6
  • 40
    • 77949540980 scopus 로고    scopus 로고
    • SZGR: A comprehensive schizophrenia gene resource
    • Jia P, Sun J, Guo A. Y, Zhao Z. SZGR: a comprehensive schizophrenia gene resource. Mol Psychiatry 2010; 15: 453-462.
    • (2010) Mol Psychiatry , vol.15 , pp. 453-462
    • Jia, P.1    Sun, J.2    Guo, A.Y.3    Zhao, Z.4
  • 43
    • 80052567911 scopus 로고    scopus 로고
    • Stereotyped fetal brain disorganization is induced by hypoxia and requires lysophosphatidic acid receptor 1 (LPA1) signaling
    • Herr KJ, Herr DR, Lee CW, Noguchi K, Chun J. Stereotyped fetal brain disorganization is induced by hypoxia and requires lysophosphatidic acid receptor 1 (LPA1) signaling. Proc Natl Acad Sci USA 2011; 108: 15444-15449.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 15444-15449
    • Herr, K.J.1    Herr, D.R.2    Lee, C.W.3    Noguchi, K.4    Chun, J.5
  • 44
    • 68949177120 scopus 로고    scopus 로고
    • Glutaminase-deficient mice display hippocampal hypoactivity, insensitivity to propsychotic drugs and potentiated latent inhibition: Relevance to schizophrenia
    • Gaisler-Salomon I, Miller GM, Chuhma N, Lee S, Zhang H, Ghoddoussi F et al. Glutaminase-deficient mice display hippocampal hypoactivity, insensitivity to propsychotic drugs and potentiated latent inhibition: relevance to schizophrenia. Neuropsychopharmacology 2009; 34: 2305-2322.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 2305-2322
    • Gaisler-Salomon, I.1    Miller, G.M.2    Chuhma, N.3    Lee, S.4    Zhang, H.5    Ghoddoussi, F.6
  • 45
    • 84867582955 scopus 로고    scopus 로고
    • Brain-specific overexpression of trace amine-associated receptor 1 alters monoaminergic neurotransmission and decreases sensitivity to amphetamine
    • Revel FG, Meyer CA, Bradaia A, Jeanneau K, Calcagno E, André CB et al. Brain-specific overexpression of trace amine-associated receptor 1 alters monoaminergic neurotransmission and decreases sensitivity to amphetamine. Neuropsychopharmacology 2012; 37: 2580-2592.
    • (2012) Neuropsychopharmacology , vol.37 , pp. 2580-2592
    • Revel, F.G.1    Meyer, C.A.2    Bradaia, A.3    Jeanneau, K.4    Calcagno, E.5    André, C.B.6
  • 47
    • 0036307319 scopus 로고    scopus 로고
    • Androgens and estrogens modulate the immune and inflammatory responses in rheumatoid arthritis
    • Cutolo M, Seriolo B, Villaggio B, Pizzorni C, Craviotto C, Sulli A. Androgens and estrogens modulate the immune and inflammatory responses in rheumatoid arthritis. Ann N Y Acad Sci 2002; 966: 131-142.
    • (2002) Ann N y Acad Sci , vol.966 , pp. 131-142
    • Cutolo, M.1    Seriolo, B.2    Villaggio, B.3    Pizzorni, C.4    Craviotto, C.5    Sulli, A.6
  • 48
  • 49
    • 0037162025 scopus 로고    scopus 로고
    • Lysophospholipids and their G protein-coupled receptors in inflammation and immunity
    • Graler MH, Goetzl EJ. Lysophospholipids and their G protein-coupled receptors in inflammation and immunity. Biochim Biophys Acta 2002; 1582: 168-174.
    • (2002) Biochim Biophys Acta , vol.1582 , pp. 168-174
    • Graler, M.H.1    Goetzl, E.J.2
  • 54
    • 84862562765 scopus 로고    scopus 로고
    • Critical-period plasticity in the visual cortex
    • Levelt CN, Hubener M. Critical-period plasticity in the visual cortex. Annu Rev Neurosci 2012; 35: 309-330.
    • (2012) Annu Rev Neurosci , vol.35 , pp. 309-330
    • Levelt, C.N.1    Hubener, M.2
  • 55
    • 84904600448 scopus 로고    scopus 로고
    • Lysophospholipid receptor nomenclature review: IUPHAR Review 8
    • Kihara Y, Maceyka M, Spiegel S, Chun J. Lysophospholipid receptor nomenclature review: IUPHAR Review 8. Br J Pharmacol 2014; 171: 3575-3594.
    • (2014) Br J Pharmacol , vol.171 , pp. 3575-3594
    • Kihara, Y.1    MacEyka, M.2    Spiegel, S.3    Chun, J.4
  • 56
    • 84927910698 scopus 로고    scopus 로고
    • Lysophospholipid receptors in drug discovery
    • in press
    • Kihara Y, Mizuno H, Chun J. Lysophospholipid receptors in drug discovery. Exp Cell Res 2014; 14: in press.
    • (2014) Exp Cell Res , vol.14
    • Kihara, Y.1    Mizuno, H.2    Chun, J.3
  • 57
    • 84555197737 scopus 로고    scopus 로고
    • A mechanistically novel, first oral therapy for multiple sclerosis: The development of fingolimod (FTY720, Gilenya)
    • Chun J, Brinkmann V. A mechanistically novel, first oral therapy for multiple sclerosis: the development of fingolimod (FTY720, Gilenya). Discov Med 2011; 12: 213-228.
    • (2011) Discov Med , vol.12 , pp. 213-228
    • Chun, J.1    Brinkmann, V.2
  • 58
    • 79955455801 scopus 로고    scopus 로고
    • Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis
    • Cohen JA, Chun J. Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis. Ann Neurol 2011; 69: 759-777.
    • (2011) Ann Neurol , vol.69 , pp. 759-777
    • Cohen, J.A.1    Chun, J.2
  • 59
    • 42749095376 scopus 로고    scopus 로고
    • Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia
    • Lisman JE, Coyle JT, Green RW, Javitt DC, Benes FM, Heckers S et al. Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia. Trends Neurosci 2008; 31: 234-242.
    • (2008) Trends Neurosci , vol.31 , pp. 234-242
    • Lisman, J.E.1    Coyle, J.T.2    Green, R.W.3    Javitt, D.C.4    Benes, F.M.5    Heckers, S.6
  • 60
    • 84873471979 scopus 로고    scopus 로고
    • Impaired GABAergic neurotransmission in schizophrenia underlies impairments in cortical gamma band oscillations
    • McNally JM, McCarley RW, Brown RE. Impaired GABAergic neurotransmission in schizophrenia underlies impairments in cortical gamma band oscillations. Curr Psychiatry Rep 2013; 15: 346.
    • (2013) Curr Psychiatry Rep , vol.15 , pp. 346
    • McNally, J.M.1    McCarley, R.W.2    Brown, R.E.3
  • 61
    • 84855557361 scopus 로고    scopus 로고
    • Glutamate signaling in the pathophysiology and therapy of schizophrenia
    • Lin C-H, Lane H-Y, Tsai GE. Glutamate signaling in the pathophysiology and therapy of schizophrenia. Pharmacol Biochem Behav 2012; 100: 665-677.
    • (2012) Pharmacol Biochem Behav , vol.100 , pp. 665-677
    • Lin, C.-H.1    Lane, H.-Y.2    Tsai, G.E.3
  • 62
    • 36849089634 scopus 로고    scopus 로고
    • Lysophosphatidic acid stimulates astrocyte proliferation through LPA1
    • Shano S, Moriyama R, Chun J, Fukushima N. Lysophosphatidic acid stimulates astrocyte proliferation through LPA1. Neurochem Int 2008; 52: 216-220.
    • (2008) Neurochem Int , vol.52 , pp. 216-220
    • Shano, S.1    Moriyama, R.2    Chun, J.3    Fukushima, N.4
  • 63
    • 33646569928 scopus 로고    scopus 로고
    • The role of LPA1 in formation of synapses among cultured hippocampal neurons
    • Pilpel Y, Segal M. The role of LPA1 in formation of synapses among cultured hippocampal neurons. J Neurochem 2006; 97: 1379-1392.
    • (2006) J Neurochem , vol.97 , pp. 1379-1392
    • Pilpel, Y.1    Segal, M.2
  • 64
    • 33644824721 scopus 로고    scopus 로고
    • Regionspecific reduction in entorhinal gamma oscillations and parvalbumin-immunoreactive neurons in animal models of psychiatric illness
    • Cunningham MO, Hunt J, Middleton S, LeBeau FE, Gillies MJ, Davies CH et al. Regionspecific reduction in entorhinal gamma oscillations and parvalbumin-immunoreactive neurons in animal models of psychiatric illness. J Neurosci 2006; 26: 2767-2776.
    • (2006) J Neurosci , vol.26 , pp. 2767-2776
    • Cunningham, M.O.1    Hunt, J.2    Middleton, S.3    Lebeau, F.E.4    Gillies, M.J.5    Davies, C.H.6
  • 65
    • 70149110413 scopus 로고    scopus 로고
    • Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling
    • Trimbuch T, Beed P, Vogt J, Schuchmann S, Maier N, Kintscher M et al. Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling. Cell 2009; 138: 1222-1235.
    • (2009) Cell , vol.138 , pp. 1222-1235
    • Trimbuch, T.1    Beed, P.2    Vogt, J.3    Schuchmann, S.4    Maier, N.5    Kintscher, M.6
  • 66
    • 17844382139 scopus 로고    scopus 로고
    • G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the {beta}-catenin pathway
    • Yang M, Zhong WW, Srivastava N, Slavin A, Yang J, Hoey T et al. G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the {beta}-catenin pathway. Proc Natl Acad Sci USA 2005; 102: 6027-6032.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 6027-6032
    • Yang, M.1    Zhong, W.W.2    Srivastava, N.3    Slavin, A.4    Yang, J.5    Hoey, T.6
  • 67
    • 79960698096 scopus 로고    scopus 로고
    • Lysophosphatidic acid induces neurite retraction in differentiated neuroblastoma cells via GSK-3β activation
    • Sun Y, Kim N-H, Yang H, Kim S-H, Huh S-O. Lysophosphatidic acid induces neurite retraction in differentiated neuroblastoma cells via GSK-3β activation. Mol Cells 2011; 31: 483-489.
    • (2011) Mol Cells , vol.31 , pp. 483-489
    • Sun, Y.1    Kim, N.-H.2    Yang, H.3    Kim, S.-H.4    Huh, S.-O.5
  • 68
    • 62149083806 scopus 로고    scopus 로고
    • Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3b/b-catenin signaling
    • Mao Y, Ge X, Frank CL, Madison JM, Koehler AN, Doud MK et al. Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3b/b-catenin signaling. Cell 2009; 136: 1017-1031.
    • (2009) Cell , vol.136 , pp. 1017-1031
    • Mao, Y.1    Ge, X.2    Frank, C.L.3    Madison, J.M.4    Koehler, A.N.5    Doud, M.K.6
  • 70
    • 67749114055 scopus 로고    scopus 로고
    • Immune involvement in schizophrenia and autism: Etiology, pathology and animal models
    • Patterson PH. Immune involvement in schizophrenia and autism: etiology, pathology and animal models. Behav Brain Res 2009; 204: 313-321.
    • (2009) Behav Brain Res , vol.204 , pp. 313-321
    • Patterson, P.H.1
  • 71
    • 33644859267 scopus 로고    scopus 로고
    • Outcomes in children experiencing neurologic insults as preterm neonates
    • 451-446
    • Gardner MR. Outcomes in children experiencing neurologic insults as preterm neonates. Pediatr Nurs 2005; 31: 448, 451-446.
    • (2005) Pediatr Nurs , vol.31 , pp. 448
    • Gardner, M.R.1
  • 72
    • 0032170840 scopus 로고    scopus 로고
    • Pre- and perinatal complications and risk for bipolar disorder: A retrospective study
    • Kinney DK, Yurgelun-Todd DA, Tohen M, Tramer S. Pre- and perinatal complications and risk for bipolar disorder: a retrospective study. J Affect Disord 1998; 50: 117-124.
    • (1998) J Affect Disord , vol.50 , pp. 117-124
    • Kinney, D.K.1    Yurgelun-Todd, D.A.2    Tohen, M.3    Tramer, S.4
  • 73
    • 0034544665 scopus 로고    scopus 로고
    • Obstetric complications in patients with depression-A population-based case-control study
    • Preti A, Cardascia L, Zen T, Pellizzari P, Marchetti M, Favaretto G et al. Obstetric complications in patients with depression-a population-based case-control study. J Affect Disord 2000; 61: 101-106.
    • (2000) J Affect Disord , vol.61 , pp. 101-106
    • Preti, A.1    Cardascia, L.2    Zen, T.3    Pellizzari, P.4    Marchetti, M.5    Favaretto, G.6
  • 74
    • 67650869592 scopus 로고    scopus 로고
    • Prenatal risk factors for autism: Comprehensive meta-analysis
    • Gardener H, Spiegelman D, Buka SL. Prenatal risk factors for autism: comprehensive meta-analysis. Br J Psychiatry 2009; 195: 7-14.
    • (2009) Br J Psychiatry , vol.195 , pp. 7-14
    • Gardener, H.1    Spiegelman, D.2    Buka, S.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.