SZGR: A comprehensive schizophrenia gene resource

Molecular Psychiatry

Volumn 15, Issue 5, 2010, Pages 453-462

  Jia, P ^a   Sun, J ^a   Guo, A Y ^b   Zhao, Z ^a,b,c  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c VANDERBILT INGRAM CANCER CENTER   (United States)

Author keywords

Association; Candidate gene; Data integration; Gene ranking; Linkage; Schizophrenia

Indexed keywords

MICRORNA;

COMPUTER INTERFACE; DATA BASE; GENE EXPRESSION; GENE REGULATORY NETWORK; GENETIC ASSOCIATION; GENETIC LINKAGE; HUMAN; INFORMATION RETRIEVAL; INTERNET; NONHUMAN; ONLINE SYSTEM; PRIORITY JOURNAL; REVIEW; SCHIZOPHRENIA; SCHIZOPHRENIA GENE RESOURCE;

COMPUTATIONAL BIOLOGY; DATABASE MANAGEMENT SYSTEMS; DATABASES, GENETIC; GENE EXPRESSION; HUMANS; LINKAGE (GENETICS); MICRORNAS; SCHIZOPHRENIA;

EID: 77949540980     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2009.93     Document Type: Review

References (36)

1. Owen MJ, Craddock N, O'Donovan MC. Schizophrenia: genes at last? Trends Genet 2005; 21: 518-525. (Pubitemid 41132587)
2. Sullivan PF, Kendler KS, Neale MC. Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies. Arch Gen Psychiatry 2003; 60: 1187-1192.
3. Burmeister M, McInnis MG, Zollner S. Psychiatric genetics: progress amid controversy. Nat Rev Genet 2008; 9: 527-540. (Pubitemid 351972757)
4. Konneker T, Barnes T, Furberg H, Losh M, Bulik CM, Sullivan PF. A searchable database of genetic evidence for psychiatric disorders. Am J Med Genet B Neuropsychiatr Genet 2008; 147B: 671-675.
5. Allen NC, Bagade S, McQueen MB, Ioannidis JP, Kavvoura FK, Khoury MJ et al. Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nat Genet 2008; 40: 827-834. (Pubitemid 351913655)
6. Sullivan PF, Lin D, Tzeng JY, van den Oord E, Perkins D, Stroup TS et al. Genomewide association for schizophrenia in the CATIE study: results of stage 1. Mol Psychiatry 2008; 13: 570-584. (Pubitemid 351704941)
7. Williams HJ, Owen MJ, O'Donovan MC. Schizophrenia genetics: new insights from new approaches. Br Med Bull 2009; 91: 61-74.
8. Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, Sullivan PF et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 2009; 460: 748-752.
9. Lewis CM, Levinson DF, Wise LH, DeLisi LE, Straub RE, Hovatta I et al. Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. Am J Hum Genet 2003; 73: 34-48. (Pubitemid 36793778)
10. Ng MYM, Levinson DF, Faraone SV, Suarez BK, DeLisi LE, Arinami T et al. Meta-analysis of 32 genome-wide linkage studies of schizophrenia. Mol Psychiatry 2009; 14: 774-785.
11. Higgs BW, Elashoff M, Richman S, Barci B. An online database for brain disease research. BMC Genomics 2006; 7: 70. (Pubitemid 44026743)
12. Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM et al. Gene ontology: tool for the unification of biology. Nat Genet 2000; 25: 25-29. (Pubitemid 30257031)
13. Kanehisa M, Araki M, Goto S, Hattori M, Hirakawa M, Itoh M et al. KEGG for linking genomes to life and the environment. Nucleic Acids Res 2008; 36: D480-D484. (Pubitemid 351149770)
14. Zhou M, Zhuang YL, Xu Q, Li YD, Shen Y. VSD: a database for schizophrenia candidate genes focusing on variations. Hum Mutat 2004; 23: 1-7. (Pubitemid 38056095)
15. Sun J, Jia P, Fanous AH, Webb BT, van den Oord EJCG, Chen X et al. A multi-dimensional evidence-based candidate gene prioritization approach for complex diseases-schizophrenia as a case. Bioinformatics 2009; doi:10.1093/bioinformatics/btp428; published online 14 July 2009.
16. Sun J, Kuo PH, Riley BP, Kendler KS, Zhao Z. Candidate genes for schizophrenia: a survey of association studies and gene ranking. Am J Med Genet B Neuropsychiatr Genet 2008; 147B: 1173-1181.
17. Peri S, Navarro JD, Amanchy R, Kristiansen TZ, Jonnalagadda CK, Surendranath V et al. Development of human protein reference database as an initial platform for approaching systems biology in humans. Genome Res 2003; 13: 2363-2371. (Pubitemid 37266003)
18. Bader GD, Donaldson I, Wolting C, Ouellette BF, Pawson T, Hogue CW. BIND-The Biomolecular Interaction Network Database. Nucleic Acids Res 2001; 29: 242-245. (Pubitemid 32054459)
19. Hermjakob H, Montecchi-Palazzi L, Lewington C, Mudali S, Kerrien S, Orchard S et al. IntAct: an open source molecular interaction database. Nucleic Acids Res 2004; 32: D452-D455. (Pubitemid 38081697)
20. Zanzoni A, Montecchi-Palazzi L, Quondam M, Ausiello G, Helmer-Citterich M, Cesareni G. MINT: a Molecular INTeraction database. FEBS Lett 2002; 513: 135-140. (Pubitemid 34242991)
21. Matthews L, Gopinath G, Gillespie M, Caudy M, Croft D, de Bono B et al. Reactome knowledgebase of human biological pathways and processes. Nucleic Acids Res 2009; 37: D619-D622.
22. Salwinski L, Miller CS, Smith AJ, Pettit FK, Bowie JU, Eisenberg D. The Database of Interacting Proteins: 2004 update. Nucleic Acids Res 2004; 32: D449-D451.
23. Ross CA, Margolis RL, Reading SA, Pletnikov M, Coyle JT. Neurobiology of schizophrenia. Neuron 2006; 52: 139-153. (Pubitemid 44466356)
24. Witten TM, Bonchev D. Predicting aging/longevity-related genes in the nematode Caenorhabditis elegans. Chem Biodivers 2007; 4: 2639-2655. (Pubitemid 350193489)
25. Managbanag JR, Witten TM, Bonchev D, Fox LA, Tsuchiya M, Kennedy BK et al. Shortest-path network analysis is a useful approach toward identifying genetic determinants of longevity. PLoS ONE 2008; 3: e3802.
26. Beveridge NJ, Tooney PA, Carroll AP, Gardiner E, Bowden N, Scott RJ et al. Dysregulation of miRNA 181b in the temporal cortex in schizophrenia. Hum Mol Genet 2008; 17: 1156-1168. (Pubitemid 351494187)
27. Perkins DO, Jeffries CD, Jarskog LF, Thomson JM, Woods K, Newman MA et al. microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder. Genome Biol 2007; 8: R27. (Pubitemid 351851029)
28. Burmistrova OA, Goltsov AY, Abramova LI, Kaleda VG, Orlova VA, Rogaev EI. MicroRNA in schizophrenia: genetic and expression analysis of miR-130b (22q11). Biochemistry (Mosc) 2007; 72: 578-582.
29. Zhang R, Su B. MicroRNA regulation and the variability of human cortical gene expression. Nucleic Acids Res 2008; 36: 4621-4628.
30. Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A et al. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 2007; 129: 1401-1414. (Pubitemid 46970709)
31. Liang Y, Ridzon D, Wong L, Chen C. Characterization of microRNA expression profiles in normal human tissues. BMC Genomics 2007; 8: 166. (Pubitemid 47019476)
32. Su AI, Wiltshire T, Batalov S, Lapp H, Ching KA, Block D et al. A gene atlas of the mouse and human protein-encoding tran-scriptomes. Proc Natl Acad Sci USA 2004; 101: 6062-6067. (Pubitemid 38520528)
33. Wu X, Jiang R, Zhang MQ, Li S. Network-based global inference of human disease genes. Mol Syst Biol 2008; 4: 189. (Pubitemid 351655223)
34. Klein P, Ravi RA. Nearly best-possible approximation algorithm for node-weighted Steiner trees. J Algorithms 1995; 19: 104-115.
35. The International Schizophrenia Consortium. Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature 2008; 455: 237-241.
36. Walsh T, McClellan JM, McCarthy SE, Addington AM, Pierce SB, Cooper GM et al. Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia. Science 2008; 320: 539-543. (Pubitemid 351590668)