Evaluation of Crimean-Congo hemorrhagic fever virus in vitro inhibition by chloroquine and chlorpromazine, two FDA approved molecules

Antiviral Research

Volumn 118, Issue , 2015, Pages 75-81

  Ferraris, O ^a   Moroso, M ^b   Pernet, O ^c,d   Emonet, S ^a   Ferrier Rembert, A ^a   Paranhos Baccala G ^b   Peyrefitte, C N ^a,b  

^a INSTITUT DE RECHERCHE BIOMÉDICALE DES ARMÉES   (France)

^b Fondation Mérieux Laboratoire des Pathogènes Émergents   (France)

^c CENTRE INTERNATIONAL DE RECHERCHE EN INFECTIOLOGIE   (France)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antiviral; Chloroquine; Chlorpromazine; Crimean Congo hemorrhagic fever virus; Ribavirin

Indexed keywords

CHLOROQUINE; CHLORPROMAZINE; RIBAVIRIN; ANTIVIRUS AGENT;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRIMEAN CONGO HEMORRHAGIC FEVER VIRUS; CYTOTOXICITY; DRUG EFFICACY; DRUG POTENTIATION; DRUG REPOSITIONING; DRUG SCREENING; DRUG SELECTIVITY; IC50; IN VITRO STUDY; LIVER CELL; MOLECULE; NONHUMAN; PRIORITY JOURNAL; VERO CELL LINE; VIRUS ENTRY; VIRUS LOAD; VIRUS NEUTRALIZATION; VIRUS REPLICATION; VIRUS STRAIN; VIRUS TRANSMISSION; ANIMAL; CELL LINE; DRUG EFFECTS; HUMAN; MICROBIAL SENSITIVITY TEST; NAIROVIRUS; PHYSIOLOGY;

CRIMEAN-CONGO HEMORRHAGIC FEVER VIRUS;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CHLOROQUINE; CHLORPROMAZINE; DRUG REPOSITIONING; DRUG SYNERGISM; HEMORRHAGIC FEVER VIRUS, CRIMEAN-CONGO; HUMANS; INHIBITORY CONCENTRATION 50; MICROBIAL SENSITIVITY TESTS; RIBAVIRIN; VIRUS INTERNALIZATION;

EID: 84926289466     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2015.03.005     Document Type: Article

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