Detection of main metabolites of XLR-11 and its thermal degradation product in human hepatoma HepaRG cells and human urine

Drug Testing and Analysis

Volumn 7, Issue 4, 2015, Pages 341-345

  Kanamori, Tatsuyuki ^a   Kanda, Koji ^a   Yamamuro, Tadashi ^a   Kuwayama, Kenji ^a   Tsujikawa, Kenji ^a   Iwata, Yuko Togawa ^a   Inoue, Hiroyuki ^a  

^a NATIONAL RESEARCH INSTITUTE OF POLICE SCIENCE   (Japan)

Author keywords

Hepatocyte; Metabolism; Synthetic cannabinoid; Urine

Indexed keywords

BIOMOLECULES; BODY FLUIDS; CELL CULTURE; CELLS; DEGRADATION; LIQUID CHROMATOGRAPHY; METABOLITES; PHYSIOLOGY;

CELL/B.E; CULTURE MEDIUM; DEGRADATION PRODUCTS; HEPATOCYTES; HUMAN HEPATOMAS; HUMAN URINE; METHANONE; SYNTHETIC CANNABINOID; THERMAL DEGRADATION'; URINE;

METABOLISM;

CANNABINOID; DRUG METABOLITE; N (5 HYDROXYPENTYL); UNCLASSIFIED DRUG; VALERIC ACID; [1 (5 FLUOROPENTYL) 1H INDOL 3 YL](2,2,3,3 TETRAMETHYLCYCLOPROPYL)METHANONE; XLR-11;

ADULT; ARTICLE; CARBOXYLATION; CRYOPRESERVATION; DRUG DEGRADATION; DRUG DETERMINATION; DRUG METABOLISM; DRUG URINE LEVEL; ELECTROSPRAY; HEATING; HEPARG CELL LINE; HUMAN; HUMAN CELL; HYDROLYSIS; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; LIVER CANCER CELL LINE; LIVER CELL CULTURE; MALE; MASS SPECTROMETRY; METABOLITE; MOLECULAR WEIGHT; PRIORITY JOURNAL; URINALYSIS; DRUG USE; HEAT; LIQUID LIQUID EXTRACTION; MASS FRAGMENTOGRAPHY; METABOLISM; PROCEDURES; SUBSTANCE ABUSE; TANDEM MASS SPECTROMETRY; TUMOR CELL LINE; URINE;

CANNABINOIDS; CELL LINE, TUMOR; CHROMATOGRAPHY, LIQUID; DRUG USERS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HOT TEMPERATURE; HUMANS; LIQUID-LIQUID EXTRACTION; SUBSTANCE ABUSE DETECTION; TANDEM MASS SPECTROMETRY;

EID: 84926248124     PISSN: 19427603     EISSN: 19427611     Source Type: Journal    
DOI: 10.1002/dta.1765     Document Type: Article

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