A new delivery system for auristatin in STxB-drug conjugate therapy

European Journal of Medicinal Chemistry

Volumn 95, Issue , 2015, Pages 483-491

  Batisse, Cornélie ^a,b   Dransart, Estelle ^a   Ait Sarkouh, Rafik ^a   Brulle, Laura ^a   Bai, Siau Kun ^a   Godefroy, Sylvie ^b   Johannes, Ludger ^a   Schmidt, Frédéric ^a  

^a CNRS   (France)

^b Immuno Targets SAS   (France)

Author keywords

Auristatin; Cancer; Carbamate; Conjugate; Disulfide; Shiga toxin

Indexed keywords

2 (PYRIDIN 2 YLDISULFANYL)ETHANOL; 2 [(3 NITROPYRIDIN 2 YL)DISULFANYL)ETHANOL; 2 [N (CHLOROCARBONYL) N METHYLAMINO]1 ETHYL 2 PYRIDYLDISULFIDE; 2 [N (TERT BUTYLOXYCARBONYL) N METHYLAMINO]1 ETHYL 2 PYRIDYLDISULFIDE; 2 [N (TERT BUTYLOXYCARBONYL) N METHYLAMINO]ACETYLTHIOETHYL; 2 [N (TERT BUTYLOXYCARBONYL) N METHYLAMINO]ETHANOL; 2 [N METHYLAMINO]1 ETHYL 2 PYRIDYLDISULFIDE; 4 NITROPHENYL [2 (PYRIDIN 2 YLDISULFANYL)ETHYL]CARBONATE; 4 NITROPHENYL [2 [(3 NITROPYRIDIN 2 YL)DISULFANYL]ETHYL] CARBONATE; ANTINEOPLASTIC AGENT; AURISTATIN; CARBAMIC ACID; N TERT BUTOXYCARBONYLMONOMETHYLAURISTATIN E; N [2 (PYRIDIN 2 YLDISULFANYL) ETHANOXYCARBONYL]MONOMETHYLAURISTATIN E; N [2 [(3 NITROPYRIDIN 2 YL)DISULFANYL]ETHANOXYCARBONYL]MONOMETHYLAURISTATIN E; O (PYRIDIN 2 YLDISULFANYL)ETHYL N METHYLAMINO) N TERTBUTOXYCARBONYLMONOMETHYLAURISTATIN E CARBAMATE; O [(PYRIDIN 2 YLDISULFANYL)ETHYL N METHYLAMINO]MONOMETHYLAURISTATIN E CARBAMATE; SHIGA TOXIN; SHIGA TOXIN B SUBUNIT; UNCLASSIFIED DRUG; [2 [(3 NITROPYRIDIN 2 YL)DISULFANYL]ETHANOL]MONOMETHYLAURISTATIN E CARBONATE; AMINOBENZOIC ACID DERIVATIVE; DRUG CARRIER; OLIGOPEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASSAY; CONJUGATE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; IN VITRO STUDY; MOUSE; NONHUMAN; TARGET CELL; CHEMICAL PHENOMENA; CHEMICAL STRUCTURE; CHEMISTRY; HT 29 CELL LINE; HUMAN; PROTEIN CONFORMATION;

AMINOBENZOATES; ANTINEOPLASTIC AGENTS; DRUG CARRIERS; HT29 CELLS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MODELS, MOLECULAR; OLIGOPEPTIDES; PROTEIN CONFORMATION; SHIGA TOXIN;

EID: 84926146656     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2015.03.047     Document Type: Article

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