Modification of the hemagglutinin cleavage site allows indirect activation of avian influenza virus H9N2 by bacterial staphylokinase

Virology

Volumn 482, Issue , 2015, Pages 1-8

  Tse, Longping V ^a,b   Whittaker, Gary R ^a,b  

^a Department of Microbiology and Immunology College of Veterinary Medicine Cornell University C4127 VMC ^*  (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Avian influenza; Bacterial co infection; Hemagglutinin; Influenza virus; Plasmin; Protease

Indexed keywords

INFLUENZA VIRUS HEMAGGLUTININ; PLASMIN; PLASMINOGEN; SIALIDASE; STAPHYLOKINASE; STREPTOKINASE A; STREPTOKINASE B; STREPTOKINASE DERIVATIVE; UNCLASSIFIED DRUG; AUR PROTEIN, STAPHYLOCOCCUS AUREUS; METALLOPROTEINASE;

AMINO ACID SUBSTITUTION; ARTICLE; BIOTINYLATION; CHICKEN; CLADISTICS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; GENE MUTATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLUENZA VIRUS A H9N2; INFLUENZA VIRUS A KOREA MS96 CE6 1996 H9N2; MURINE LEUKEMIA VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; SEQUENCE ALIGNMENT; STREPTOCOCCUS; VIRUS ACTIVATION; VIRUS EXAMINATION; VIRUS PARTICLE; VIRUS STRAIN; WESTERN BLOTTING; WILD TYPE; ANIMAL; DRUG EFFECTS; EPIDEMIC; GENETICS; INFLUENZA A VIRUS (H9N2); INFLUENZA IN BIRDS; ISOLATION AND PURIFICATION; KOREA; METABOLISM; MISSENSE MUTATION; ORGANISMAL INTERACTION; VIROLOGY; VIRULENCE;

AVES; AVIAN INFLUENZA VIRUS; BACTERIA (MICROORGANISMS); GALLUS GALLUS; ORTHOMYXOVIRIDAE; STAPHYLOCOCCUS SP.;

ANIMALS; CHICKENS; DISEASE OUTBREAKS; FIBRINOLYSIN; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; INFLUENZA A VIRUS, H9N2 SUBTYPE; INFLUENZA IN BIRDS; KOREA; METALLOENDOPEPTIDASES; MICROBIAL INTERACTIONS; MUTATION, MISSENSE; VIRULENCE;

EID: 84925986946     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2015.03.023     Document Type: Article

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