Fluorescent cancer-selective alkylphosphocholine analogs for intraoperative glioma detection

Neurosurgery

Volumn 76, Issue 2, 2015, Pages 115-123

  Swanson, Kyle I ^a   Clark, Paul A ^a   Zhang, Ray R ^a,b   Kandela, Irawati K ^c   Farhoud, Mohammed ^c   Weichert, Jamey P ^c,d,e,f   Kuo, John S ^a,c,f  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b Cell and Molecular Biology Program   (United States)

^c Department of Radiology ^*  (United States)

^d UNIVERSITY OF WISCONSIN   (United States)

^e Cellectar   (United States)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Glioblastoma; Intraoperative imaging; Optical imaging; Tumor fluorescence

Indexed keywords

1,3,3 TRIMETHYL 2 [(E) 2 [(3E) 3 (2 [(2E) 1,3,3 TRIMETHYL 2,3 DIHYDRO 1H INDOL 2 YLIDENE]ETHYLIDENE 2 [4 (18 ([2 TRIMETHYLAZANIUMYL) ETHYL PHOSPHONATO]OXY)OCTADECYL)PHENYL]CYCLOHEX 1 EN 1 YL]ETHENYL] 3H INDOL 1 IUM; 18 [P (4,4 DIFLUORO 4 BORA 3A,4A DIAZA S INDACENE 8 YL)PHENYL] OCTADECYL PHOSPHOCHOLINE; AMINOLEVULINIC ACID; DIAGNOSTIC AGENT; UNCLASSIFIED DRUG; CLR1502; FLUORESCENT DYE; INDOLE DERIVATIVE; PHOSPHORYLCHOLINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER SURGERY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FLOW CYTOMETRY; FLUORESCENCE; FLUORESCENCE IMAGING; FLUORESCENCE IMAGING SYSTEM; GLIOBLASTOMA; HUMAN; HUMAN CELL; MOUSE; NEAR INFRARED IMAGING SYSTEM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; TUMOR XENOGRAFT; ANALOGS AND DERIVATIVES; ANIMAL; BRAIN NEOPLASMS; GLIOMA; NEAR INFRARED SPECTROSCOPY; XENOGRAFT;

AMINOLEVULINIC ACID; ANIMALS; BRAIN NEOPLASMS; FLOW CYTOMETRY; FLUORESCENT DYES; GLIOMA; HETEROGRAFTS; HUMANS; INDOLES; MAGNETIC RESONANCE IMAGING; MICE; MICROSCOPY, CONFOCAL; PHOSPHORYLCHOLINE; SPECTROSCOPY, NEAR-INFRARED;

EID: 84925946840     PISSN: 0148396X     EISSN: 15244040     Source Type: Journal    
DOI: 10.1227/NEU.0000000000000622     Document Type: Article

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