Antimicrobial Resistance and Molecular Analysis of Methicillin-Resistant Staphylococcus aureus Collected in a Spanish Hospital

Microbial Drug Resistance

Volumn 21, Issue 2, 2015, Pages 201-208

  Hernández Porto, Miriam ^a   Lecuona, María ^a   Aguirre Jaime, Armando ^b   Castro, Beatriz ^a   Delgado, Teresa ^a   Cuervo, Milagros ^a   Pedroso, Yanet ^a   Arias, Ángeles ^c  

^a HOSPITAL UNIVERSITARIO DE CANARIAS   (Spain)

^b HOSPITAL UNIVERSITARIO NUESTRA SEÑORA DE CANDELARIA   (Spain)

^c UNIVERSIDAD DE LA LAGUNA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CLINDAMYCIN; COTRIMOXAZOLE; DALFOPRISTIN PLUS QUINUPRISTIN; ERYTHROMYCIN; GENTAMICIN; LINEZOLID; RIFAMPICIN; TOBRAMYCIN; VANCOMYCIN; ANTIINFECTIVE AGENT;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL CHROMOSOME; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIUM ISOLATE; CLONE; COMMUNITY; HOSPITAL; HOSPITAL INFECTION; LIVESTOCK; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; SPAIN; ANIMAL; CROSS INFECTION; DRUG EFFECTS; GENETICS; HUMAN; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; PENICILLIN RESISTANCE; PROCEDURES; STAPHYLOCOCCAL INFECTIONS;

METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS;

ANIMALS; ANTI-INFECTIVE AGENTS; CROSS INFECTION; HOSPITALS; HUMANS; LIVESTOCK; METHICILLIN RESISTANCE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; SPAIN; STAPHYLOCOCCAL INFECTIONS;

EID: 84925941310     PISSN: 10766294     EISSN: 19318448     Source Type: Journal    
DOI: 10.1089/mdr.2014.0139     Document Type: Article

References (38)

1. Amorim, M. L. , N. A. Faria, D. C. Oliveira, C. Vasconcelos, J. C. Cabeda, A. C. Mendes, E. Calado, A. P. Castro, M. H. Ramos, J. M. Amorim, and H. de Lencastre. 2007. Changes in the clonal nature and antibiotic resistance profiles of methicillin-resistant Staphylococcus aureus isolates associated with spread of the EMRSA-15 clone in a tertiary care Portuguese hospital. J. Clin. Microbiol. 45: 2881-2888.
2. Cercenado, E. , and E. Ruiz de Gopegui. 2008. Staphylococcus aureus resistente a la meticilina de origen comunitario. Enferm. Infecc. Clin. 26:19-24.
3. Chambers, H. F. , and F. R. Deleo. 2009. Waves of resistance: Staphylococcus aureus in the antibiotic era. Nat. Rev. Microbiol. 7:629-641.
4. Chua, K. , F. Laurent, G. Coombs, M. L. Grayson, and B. P. Howden. 2011. Antimicrobial resistance: not community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA)! A clinician's guide to community MRSA-its evolving antimicrobial resistance and implications for therapy. Clin. Infect. Dis. 52:99-114.
5. [CLSI] Clinical and Laboratory Standards Institute. 2009. Performance standards for antimicrobial susceptibility testing; nineteenth information supplement. January. Vol. 29 Available at www. clsi. org, accessed February 17, 2013. (Online. ).
6. David, M. Z. , and R. S. Daum. 2010. Community-associated methicillin-resistant Staphylococcus aureus: epidemiology and clinical consequences of an emerging epidemic. Clin. Microbiol. Rev. 23:616-687.
7. Delgado Melian, T. 2009. Estudio epidemiologico de Staphylococcus aureus resistente a meticilina aislados en el Hospital Universitario de Canarias (2000-2004). Servicio de Publicaciones de la Universidad de la Laguna, San Cristobal de La Laguna, Spain.
8. Enright, M. C. , N. P. Day, C. E. Davies, S. J. Peacock, and B. G. Spratt. 2000. Multilocus sequence typing for characterization of methicillin-resistant and methicillinsusceptible clones of Staphylococcus aureus. J. Clin. Microbiol. 38:1008-1015.
9. Garcia-Garrote, F. , E. Cercenado, M. Marin, M. Bal, P. Trincado, J. Corredoira, C. Ballesteros, J. Pita, P. Alonso, and A. Vindel. 2014. Methicillin-resistant Staphylococcus aureus carrying the mecC gene: emergence in Spain and report of a fatal case of bacteraemia. J. Antimicrob. Chemother. 69:45-50.
10. Gonzalez-Dominguez, M. , C. Seral, Y. Saenz, S. Salvo, M. J. Gude, N. Porres-Osante, C. Torres, and F. J. Castillo. 2012. Epidemiological features, resistance genes, and clones among community-onset methicillin-resistant Staphylococcus aureus (CO-MRSA) isolates detected in northern Spain. Int. J. Med. Microbiol. 302:320-326.
11. Guerrero, C. , and C. Sanchez. Recogida, transporte y procesamiento general de las muestras en el laboratorio de microbiologia. Available at www. seimc. org/contenidos/ documentoscientificos/procedimientosmicrobiologia/seimcprocedimientomicrobiologia1a. pdf, accessed October 10, 2010.
12. Horan, T. C. , M. Andrus, and M. A. Dudeck. 2008. CDC/ NHSN Surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am. J. Infect. Control 36:309-332.
13. Kinnevey, P. M. , A. C. Shore, G. I. Brennan, D. J. Sullivan, R. Ehricht, S. Monecke, and D. C. Coleman. 2014. Extensive genetic diversity identified among sporadic methicillin-resistant Staphylococcus aureus isolates recovered in Irish hospitals between 2000-2012. Antimicrob. Agents Chemother. 58:1907-1917.
14. Köck, R. , K. Becker, B. Cookson, J. E. van Gemert-Pijnen, S. Harbarth, J. Kluytmans, M. Mielke, G. Peters, R. L. Skov, M. J. Struelens, E. Tacconelli, A. Navarro Torne, W. Witte, and A. W. Friedrich. 2010. Methicillinresistant Staphylococcus aureus (MRSA): burden of disease and control challenges in Europe. Euro. Surveill. 15:19688.
15. Medina, G. , A. L. Egea, C. Otth, L. Otth, H. Fernandez, J. L. Bocco, M. Wilson, and C. Sola. 2013. Molecular epidemiology of hospital-onset methicillin-resistant Staphylococcus aureus infections in Southern Chile. Eur. J. Clin. Microbiol. Infect. Dis. 32:1533-1540.
16. Menegotto, F. , S. Gonzalez-Cabrero, B. Lorenzo, A. Cubero, W. Cuervo, M. P. Gutierrez, M. Simarro, A. Ordunã, and M. A. Bratos. 2012. Molecular epidemiology of methicillin-resistant Staphylococcus aureus in a Spanish hospital over a 4-year period: clonal replacement, decreased antimicrobial resistance, and identification of community-acquired and livestock-associated clones. Diagn. Microbiol. Infect. Dis. 74:332-337.
17. Monecke, S. , G. Coombs, A. C. Shore, D. C. Coleman, P. Akpaka, M. Borg, H. Chow, M. Ip, L. Jatzwauk, D. Jonas, K. Kadlec, A. Kearns, F. Laurent, F. G. O'Brien, J. Pearson, A. Ruppelt, S. Schwarz, E. Scicluna, P. Slickers, H. L. Tan, S. Weber, and R. Ehricht. 2011. A field guide to pandemic, epidemic and sporadic clones of methicillin-resistant Staphylococcus aureus. PLoS One 6:e17936.
18. Montesinos, I. , E. Salido, T. Delgado, M. Lecuona, and A. Sierra. 2003. Epidemiology of methicillin-resistant Staphylococcus aureus at a university hospital in the Canary Islands. Infect. Control Hosp. Epidemiol. 24:667-672.
19. Oliveira, D. C. , and H. de Lencastre. 2002. Multiplex PCR strategy for rapid identification of structural types and variants of the mec element in methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 46:2155-2161.
20. Otter, J. A. , and G. L. French. 2010. Molecular epidemiology of community-associated methicillin-resistant Staphylococcus aureus in Europe. Lancet Infect. Dis. 10:227-239.
21. Paterson, G. K. , E. M. Harrison, and M. A. Holmes. 2014. The emergence of mecC methicillin-resistant Staphylococcus aureus. Trends Microbiol. 22:42-47.
22. Paterson, G. K. , F. J. Morgan, E. M. Harrison, E. J. Cartwright, M. E. Török, R. N. Zadoks, J. Parkhill, S. J. Peacock, and M. A. Holmes. 2014. Prevalence and characterization of human mecC methicillin-resistant Staphylococcus aureus isolates in England. J. Antimicrob. Chemother. 69:907-910.
23. Perez-Roth, E. , F. Lorenzo-Diaz, N. Batista, A. Moreno, and S. Mendez-Alvarez. 2004. Tracking methicillinresistant Staphylococcus aureus clones during a 5-year period (1998 to 2002) in a Spanish hospital. J. Clin. Microbiol. 42:4649-4656.
24. Qi, W. , M. Ender, F. O'Brien, A. Imhof, C. Ruef, N. McCallum, and B. Berger-Bächi. 2005. Molecular epidemiology of methicillin-resistant Staphylococcus aureus in Zurich, Switzerland (2003): prevalence of type IV SCCmec and a new SCCmec element associated with isolates from intravenous drug users. J. Clin. Microbiol. 43:5164-5170.
25. Rivero-Perez, B. , J. Alcoba-Florez, and S. Mendez-A lvarez. 2012. Genetic diversity of community-associated methicillin-resistant Staphylococcus aureus isolated from Tenerife Island, Spain. Infect. Genet. Evol. 12:586-590.
26. Rodriguez-Banõ, J. , M. Angeles Dominguez, A. Blas Millan, C. Borraz, M. Pau Gonzalez, B. Almirante, E. Cercenado, B. Padilla, and M. Pujol. 2009. Clinical and molecular epidemiology of community-acquired, healthcare-associated and nosocomial methicillin-resistant Staphylococus aureus in Spain. Clin. Microbiol. Infect. 15:1111-1118.
27. Sapri, H. F. , N. A. Sani, H. M. Neoh, and S. Hussin. 2013. Epidemiological study on Staphylococcus aureus isolates reveals inverse relationship between antibiotic resistance and virulence repertoire. Indian J. Microbiol. 53: 321-322.
28. Schaumburg, F. , E. A. Idelevich, G. Peters, A. Mellmann, C. von Eiff, and K. Becker. 2014. Trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus from Germany (2004-2011). Clin. Microbiol. Infect. 20:0554-O557.
29. Shore, A. C. , E. C. Deasy, P. Slickers, G. Brennan, B. O'Connell, S. Monecke, R. Ehricht, and D. C. Coleman. 2011. Detection of staphylococcal cassette chromosome mec type XI carrying highly divergent mecA, mecI, mecR1, blaZ, and ccr genes in human clinical isolates of clonal complex 130 methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 55:3765-3773.
30. Shore, A. , A. S. Rossney, C. T. Keane, M. C. Enright, and D. C. Coleman. 2005. Seven novel variants of the staphylococcal chromosomal cassette mec in methicillin-resistant Staphylococcus aureus isolates from Ireland. Antimicrob. Agents Chemother. 49:2070-2083.
31. Smith, C. L. , S. R. Klo, and C. R. Cantor. 1982. Pulsed field gel electrophoresis and the technology of large DNA molecules. In K. Davies (ed. ), Genome Analysis: A Practical Approach. IRL Press, United Kingdom, pp. 41-72.
32. Stefani, S. , D. R. Chung, J. A. Lindsay, A. W. Friedrich, A. M. Kearns, H. Westh, and F. M. Mackenzie. 2012. Methicillin-resistant Staphylococcus aureus (MRSA): global epidemiology and harmonisation of typing methods. Int. J. Antimicrob. Agents 39:273-282.
33. Teixeira, M. M. , M. C. Arau jo, M. C. Silva-Carvalho, C. O. Beltrame, C. C. Oliveira, A. M. Figueiredo, and A. G. Oliveira. 2012. Emergence of clonal complex 5 (CC5) methicillin-resistant Staphylococcus aureus (MRSA) isolates susceptible to trimethoprimsulfamethoxazole in a Brazilian hospital. Braz. J. Med. Biol. Res. 45:637-643.
34. Tenover, F. C. , R. D. Arbeit, R. V. Goering, P. A. Mickelsen, B. E. Murray, D. H. Persing, and B. Swaminathan. 1995. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J. Clin. Microbiol. 33: 2233-2239.
35. Torres-Sangiao, E. , S. Perez-Castro, M. I. Fernandez-Natal, R. Cisterna-Cancer, M. Zapico-Gonzalez, B. Fernandez-Perez, E. Ojeda-Fernandez, T. Nebreda, M. Gozalo-Margü ello, C. Fuster-Foz, M. P. Roiz-Mesones, M. D. Miguel-Martin, L. Torroba, A. Coira-Nieto, F. Vasallo-Vidal, S. Mendez-Lage, E. Prieto-Rodriguez, J. M. Eiros, J. Torres, and G. Bou. 2012. Identification of international circulating lineages of methicillin-resistant Staphylococcus aureus in the north of Spain and their glycopeptide and linezolid susceptibility. J. Med. Microbiol. 61:305-307.
36. VanHeirstraeten L. , J. Cortinãs Abrahantes,C. Lammens, A. Lee, S. Harbarth, G. Molenberghs, G. Molenberghs,M. Aerts, H. Goossens, and S. Malhotra-Kumar. 2009. Impact of a short period of pre-enrichment on detection and bacterial loads of methicillin-resistant Staphylococcus aureus from screening specimens. J. Clin. Microbiol. 47:3326-3328.
37. Vindel, A. , O. Cuevas, E. Cercenado, C. Marcos, V. Bautista, C. Castellares, P. Trincado, T. Boquete, M. Perez-Vazquez, M. Marin, and E. Bouza. 2009. Methicillin-resistant Staphylococcus aureus in Spain: molecular epidemiology and utility of different typing methods. J. Clin. Microbiol. 47:1620-1627.
38. Zhou, Y. P. , A. Wilder-Smith, and L. Y. Hsu. 2014. The role of international travel in the spread of methicillinresistant Staphylococcus aureus. J. Travel. Med. 21: 272-281.