Epidemiological Study on Staphylococcus aureus Isolates Reveals Inverse Relationship between Antibiotic Resistance and Virulence Repertoire

Indian Journal of Microbiology

Volumn 53, Issue 3, 2013, Pages 321-322

  Sapri, Hassriana Fazilla ^a   Sani, Nurul Azirah Mohamad ^a   Neoh, Hui min ^b   Hussin, Salasawati ^a  

^a DEPARTMENT OF PHARMACOLOGY   (Malaysia)

^b UNIVERSITI KEBANGSAAN MALAYSIA   (Malaysia)

Author keywords

Antibiotic resistance; MRSA; MSSA; Virulence repertoire

Indexed keywords

METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS;

EID: 84879275459     PISSN: 00468991     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12088-013-0357-4     Document Type: Article

References (9)

1. Cameron DR, Howden BP, Peleg AY (2011) The interface between antibiotics resistance and virulence in Staphylococcus aureus and its impact upon clinical outcomes. Clin Infect Dis 53: 576-582.
2. Gill SR, Fouts DE, Archer GL, Mongodin EF, Deboy RT, Ravel J, Paulsen IT, Kolonay JF, Brinkac L, Beanan M, Dodson RJ, Daugherty SC, Madupu R, Angiuoli SV, Durkin AS, Haft DH, Vamathevan J, Khouri H, Utterback T, Lee C, Dimitrov G, Jiang L, Qin H, Weidman J, Tran K, Kang K, Hance IR, Nelson KE, Fraser CM (2005) Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcusaureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain. J Bacteriol 187: 2426-2438.
3. Neoh H, Yuzawa H, Cui L, Takeuchi F, Matsuo M, Hiramatsu K (2008) Mutated response regulator graR is responsible for phenotypic conversion of Staphylococcus aureus from heterogeneous vancomycin-intermediate resistance to vancomycin-intermediate resistance. Antimicrob Agents Chemother 52: 45-53.
4. Gardete S, Kim C, Hartmann BM, Mwangi M, Roux CM, Dunman PM, Chambers HF, Tomasz A (2012) Genetic pathway in acquisition and loss of vancomycin resistance in a methicillin resistant Staphylococcus aureus (MRSA) strain of clonal type USA300. PLoS Pathog 8: e1002505.
5. Clinical and Laboratory Standards Institute (CLSI) (2012) Performance standards for antimicrobial susceptibility testing; 22nd informational supplement, M100-S22. Clinical and Laboratory Standards Institute, Wayne, PA.
6. Ma XX, Galiana A, Pedreira W, Mowszowicz M, Christophersen I, Machiavello S, Lope L, Benaderet S, Buela F, Vincentino W, Albini M, Bertaux O, Constenla I, Bagnulo H, Llosa L, Ito T, Hiramatsu K (2005) Community-acquired methicillin-resistant Staphylococcus aureus, Uruguay. Emerg Infect Dis 11: 973-976.
7. Hassriana Fazilla S, Nurul Azirah MS, Ainihayati N, Neoh H, Salasawati H (2011) Virulence gene typing of methicillin-susceptible Staphylococcus aureus (MSSA) isolates in Universiti Kebangsaan Malaysia Medical Centre (UKMMC). Asia Pac J Mol Med 1(1): 1-4.
8. Jimenez JN, Ocampo AM, Vanegas JM, Rodriguez EA, Garces CG, Patino LA, Ospina S, Correa MM (2011) Characterisation of virulence genes in methicillin susceptible and resistant Staphylococcus aureus isolates from a paediatric population in a university hospital of Medellín, Colombia. Mem Inst Oswaldo Cruz Rio de Janeiro 106: 980-985.
9. Anderson DI, Levin BR (1999) The biological cost of antibiotic resistance. Curr Opin Microbiol 2: 489-493.