-
1
-
-
33745646315
-
Ocularoxygenationandthetreatmentofdiabetic retinopathy
-
Stefansson E.Ocularoxygenationandthetreatmentofdiabetic retinopathy. Surv Ophthalmol. 2006;51:364-80.
-
(2006)
Surv Ophthalmol.
, vol.51
, pp. 364-380
-
-
Stefansson, E.1
-
3
-
-
67749088340
-
Microvascularlesionsof diabetic retinopathy:cluestowardsunderstandingpathogenesis
-
Curtis TM,GardinerTA,StittAW.Microvascularlesionsof diabetic retinopathy:cluestowardsunderstandingpathogenesis. Eye. 2009;23:1496-508.
-
(2009)
Eye.
, vol.23
, pp. 1496-1508
-
-
Curtis, T.M.1
Gardiner, T.A.2
Stitt, A.W.3
-
5
-
-
74549118204
-
Retinaloxidativestres induced byintraocularhypertensioninratsmaybeamelioratedby brimonidine treatmentandN-acetylcysteinesupplementation
-
Ozdemir G,TolunFI,GulM,ImrekS.Retinaloxidativestres induced byintraocularhypertensioninratsmaybeamelioratedby brimonidine treatmentandN-acetylcysteinesupplementation. J Glaucoma. 2009;18:662-5.
-
(2009)
J Glaucoma.
, vol.18
, pp. 662-665
-
-
Ozdemir, G.1
Tolun, F.I.2
Gulm3
Imreks4
-
6
-
-
0142138124
-
Long-term treatment with fidarestat suppressesthedevelopmentofdiabetic retinopathy inSTZ-induceddiabeticrats
-
Kato N,YashimaS,SuzukiT,NakayamaY,JomoriT.Long-term treatment with fidarestat suppressesthedevelopmentofdiabetic retinopathy inSTZ-induceddiabeticrats. J DiabetesComplications. 2003;17:374-9.
-
(2003)
J DiabetesComplications.
, vol.17
, pp. 374-379
-
-
Kato, N.1
Yashima, S.S.T.2
Nakayama, Y.3
Jomori, T.4
-
7
-
-
0036334679
-
Timecourseof NADH oxidase,induciblenitricoxidesynthaseandperoxynitritein diabetic retinopathyintheBBZ/WORrat
-
Ellis EA,GuberskiDL,HutsonB,GrantMB.Timecourseof NADH oxidase,induciblenitricoxidesynthaseandperoxynitritein diabetic retinopathyintheBBZ/WORrat. Nitric Oxide. 2002;6:295-304.
-
(2002)
Nitric Oxide.
, vol.6
, pp. 295-304
-
-
Ellis, E.A.1
Guberski, D.L.2
Hutson, B.3
Grant, M.B.4
-
9
-
-
48549088705
-
Vascularendothelialgrowthfactorineyedisease
-
Penn JS,MadanA,CaldwellRB,BartoliM,CaldwellRW,Hartnett ME. Vascularendothelialgrowthfactorineyedisease. Prog RetinEye Res. 2008;27:331-71.
-
(2008)
Prog RetinEye Res.
, vol.27
, pp. 331-371
-
-
Penn, J.S.1
Madan, A.2
Caldwell, R.B.3
Bartoli, M.4
Caldwell, R.W.5
Hartnett, M.E.6
-
10
-
-
0034824634
-
Developmentoftheprimateretinalvasculature
-
Provis JM.Developmentoftheprimateretinalvasculature. Prog Retin EyeRes. 2001;20:799-821.
-
(2001)
Prog Retin EyeRes.
, vol.20
, pp. 799-821
-
-
Provis, J.M.1
-
11
-
-
0036789574
-
Regulationofhypoxia-inducible factor1? Expression andfunctionbythemammalian target ofrapamycin
-
Hudson CC,LiuM,ChiangGG,etal.Regulationofhypoxia-inducible factor1? expression andfunctionbythemammalian target ofrapamycin. Mol CellBiol. 2002;22:7004-14.
-
(2002)
Mol CellBiol.
, vol.22
, pp. 7004-7014
-
-
Hudson, C.C.1
Liu, M.2
Chiang, G.G.3
-
13
-
-
0016724057
-
Rapamycin(Ay-22,989),anew antifungal antibiotic.I.Taxonomyoftheproducingstreptomycete and isolationoftheactiveprinciple
-
Vezina C,KudelskiA,SehgalSN.Rapamycin(Ay-22,989),anew antifungal antibiotic.I.Taxonomyoftheproducingstreptomycete and isolationoftheactiveprinciple. J Antibiot(Tokyo). 1975;28: 721-6.
-
(1975)
J Antibiot(Tokyo).
, vol.28
, pp. 721-726
-
-
Vezina, C.1
Kudelski, A.2
Sehgal, S.N.3
-
14
-
-
0036174289
-
Rapamycin inhibits primaryandmetastatictumorgrowthbyantiangiogenesis: Involvement ofvascularendothelialgrowthfactor
-
Guba M,vonBreitenbuchP,SteinbauerM,etal.Rapamycin inhibits primaryandmetastatictumorgrowthbyantiangiogenesis: involvement ofvascularendothelialgrowthfactor. Nat Med. 2002;8:128-35.
-
(2002)
Nat Med.
, vol.8
, pp. 128-135
-
-
Guba, M.1
Vonbreitenbuch, P.2
Steinbauer, M.3
-
15
-
-
26044478426
-
Rapamycinameliorates experimental autoimmunemyocarditis
-
Maeda K,ShioiT,KosugiR,etal.Rapamycinameliorates experimental autoimmunemyocarditis. Int HeartJ. 2005;46: 513-30.
-
(2005)
Int HeartJ.
, vol.46
, pp. 513-530
-
-
Maeda, K.S.T.1
Kosugi, R.2
-
16
-
-
70349562396
-
Roleof ?4 integrin(CD49d)inthepathogenesis of diabeticretinopathy
-
Iliaki E,PoulakiV,MitsiadesN,MitsiadesCS,MillerJW, Gragoudas ES.Roleof ?4 integrin(CD49d)inthepathogenesis of diabeticretinopathy. Invest OphthalmolVisSci. 2009;50: 4898-904.
-
(2009)
Invest OphthalmolVisSci.
, vol.50
, pp. 4898-4904
-
-
Iliaki, E.1
Poulaki, V.2
Mitsiades, N.3
Mitsiades, C.S.4
Miller, J.W.5
Gragoudas, E.S.6
-
17
-
-
33744907256
-
Effectofendothelindual receptor antagonistonVEGFlevelsinstreptozotocin-induced diabetic ratretina
-
Masuzawa K,JesminS,MaedaS,etal.Effectofendothelindual receptor antagonistonVEGFlevelsinstreptozotocin-induced diabetic ratretina. Exp BiolMed(Maywood). 2006;23:1090-4.
-
(2006)
Exp BiolMed(Maywood).
, vol.23
, pp. 1090-1094
-
-
Masuzawa, K.1
Jesmin, S.2
Maeda, S.3
-
18
-
-
0018384650
-
Assayforlipidperoxidesinanimal tissues bythiobarbituricacidreaction
-
Ohkawa H,OhishiN,YagiK.Assayforlipidperoxidesinanimal tissues bythiobarbituricacidreaction. Anal Biochem. 1979;95: 351-8.
-
(1979)
Anal Biochem.
, vol.95
, pp. 351-358
-
-
Ohkawa, H.1
Ohishi, N.2
Yagi, K.3
-
20
-
-
72449156165
-
Beneficial effectof docosahexanoic acidandluteinonretinalstructural,metabolic, and functionalabnormalitiesindiabeticrats
-
Arnal E,MirandaM,Johnsen-SorianoS.Beneficial effectof docosahexanoic acidandluteinonretinalstructural,metabolic, and functionalabnormalitiesindiabeticrats. Curr EyeRes. 2009; 34:928-38.
-
(2009)
Curr EyeRes.
, vol.34
, pp. 928-938
-
-
Arnal, E.1
Miranda, M.2
Johnsen-Soriano, S.3
-
21
-
-
0038243821
-
Experimentaldiabetescausesbreak-down oftheblood-retinabarrierbyamechanisminvolvingtyrosine nitration andincreasesinexpressionofvascularendothelialgrowth factor andurokinaseplasminogenactivatorreceptor
-
El-Remessy AB,BehzadianMA,Abou-MohamedG,FranklinT, Caldwell RW,CaldwellRB.Experimentaldiabetescausesbreak-down oftheblood-retinabarrierbyamechanisminvolvingtyrosine nitration andincreasesinexpressionofvascularendothelialgrowth factor andurokinaseplasminogenactivatorreceptor. Am JPathol. 2003;162:1995-2004.
-
(2003)
Am JPathol.
, vol.162
, pp. 1995-2004
-
-
El-Remessy, A.B.1
Behzadian, M.A.2
Abou-Mohamed, G.3
Franklin, T.4
Caldwell, R.W.5
Caldwell, R.B.6
-
22
-
-
0036269326
-
Thepathogenesisofdiabeticretinopathy:old concepts andnewquestions
-
Cai J,BoultonM.Thepathogenesisofdiabeticretinopathy:old concepts andnewquestions. Eye. 2002;16:242-60.
-
(2002)
Eye.
, vol.16
, pp. 242-260
-
-
Cai, J.1
Boulton, M.2
-
23
-
-
33745141162
-
Oxygen-dependentdiseasesintheretina: Role ofhypoxia-induciblefactor
-
Arjamaa O,NikinmaaM.Oxygen-dependentdiseasesintheretina: role ofhypoxia-induciblefactor. Exp EyeRes. 2006;83:473-83.
-
(2006)
Exp EyeRes.
, vol.83
, pp. 473-483
-
-
Arjamaa, O.1
Nikinmaa, M.2
-
24
-
-
0036319333
-
Diabetesinducednitrative stress intheretina,andcorrectionbyaminoguanidine
-
Du Y,SmithMA,MillerCM,KernTS.Diabetesinducednitrative stress intheretina,andcorrectionbyaminoguanidine. J Neurochem. 2002;80:771-9.
-
(2002)
J Neurochem.
, vol.80
, pp. 771-779
-
-
Du, Y.1
Smith, M.A.2
Miller, C.M.3
Kern, T.S.4
-
25
-
-
0034682961
-
Oxidants,nitricoxide and prostanoidsinthedevelopingocularvasculature:abasisfor ischemic retinopathy
-
Hardy P,DumontI,BhattacharyaM,etal.Oxidants,nitricoxide and prostanoidsinthedevelopingocularvasculature:abasisfor ischemic retinopathy. Cardiovasc Res. 2000;47:489-509.
-
(2000)
Cardiovasc Res.
, vol.47
, pp. 489-509
-
-
Hardy, P.1
Dumont, I.2
Bhattacharya, M.3
-
26
-
-
23744461597
-
Tyrosinenitrationbysuperoxide and nitricoxide fluxes inbiologicalsystems:modelingtheimpactof superoxide dismutaseandnitricoxidediffusion
-
Quijano C,RomeroN,RadiR.Tyrosinenitrationbysuperoxide and nitricoxide fluxes inbiologicalsystems:modelingtheimpactof superoxide dismutaseandnitricoxidediffusion. Free RadicBiolMed. 2005;39:728-41.
-
(2005)
Free RadicBiolMed.
, vol.39
, pp. 728-741
-
-
Quijano, C.1
Romero, N.2
Radi, R.3
-
27
-
-
0033825779
-
Elevated vitreous nitricoxidelevelsinpatientswithproliferativediabetic retinopathy
-
Yilmaz G,EsserP,KociekN,AydinP,HeimannK.Elevated vitreous nitricoxidelevelsinpatientswithproliferativediabetic retinopathy. Am JOphthalmol. 2000;130:87-90.
-
(2000)
Am JOphthalmol.
, vol.130
, pp. 87-90
-
-
Yilmaz, G.1
Esser, P.2
Kociek, N.3
Aydin, P.4
Heimann, K.5
-
28
-
-
77954423806
-
Sirolimusattenuatesreduced-size liver ischemia-reperfusion injurybutimpairsliverregenerationin rats
-
Liu YX,JinLM,ZhouL,etal.Sirolimusattenuatesreduced-size liver ischemia-reperfusion injurybutimpairsliverregenerationin rats. Dig DisSci. 2010;55:2255-62.
-
(2010)
Dig DisSci.
, vol.55
, pp. 2255-2262
-
-
Liu, Y.X.1
Jin, L.M.2
Zhou, L.3
-
29
-
-
80052965909
-
Rapamycin protectsagainstmiddlecerebralarteryocclusioninduced focal cerebralischemiainrats
-
Chauhan A,SharmaU,JagannathanNR,ReetaKH,GuptaYK. Rapamycin protectsagainstmiddlecerebralarteryocclusioninduced focal cerebralischemiainrats. Behav BrainRes. 2011;225:603-9.
-
(2011)
Behav BrainRes.
, vol.225
, pp. 603-609
-
-
Chauhan, A.1
Sharma, U.2
Jagannathan, N.R.3
Reeta, K.H.4
Gupta, Y.K.5
-
31
-
-
45549104909
-
Beneficial effectofzeaxanthin on retinalmetabolicabnormalitiesindiabeticrats
-
Kowluru RA,MenonB,GierhartDL.Beneficial effectofzeaxanthin on retinalmetabolicabnormalitiesindiabeticrats. Invest Ophthalmol Vis Sci. 2008;49:1645-51.
-
(2008)
Invest Ophthalmol Vis Sci.
, vol.49
, pp. 1645-1651
-
-
Kowluru, R.A.1
Menon, B.2
Gierhart, D.L.3
-
33
-
-
0141838834
-
Rapamycintreatmentat immunosuppressive dosesaffectstumorbloodvesselcirculation
-
Koehl G,GubaM,SeeligerH,etal.Rapamycintreatmentat immunosuppressive dosesaffectstumorbloodvesselcirculation. Transplant Proc. 2003;35:2135-6.
-
(2003)
Transplant Proc.
, vol.35
, pp. 2135-2136
-
-
Koehl, G.1
Guba, M.2
Seeliger, H.3
-
34
-
-
67650944993
-
Rapamycinfedlateinlife extends lifespaningeneticallyheterogeneousmice
-
Harrison DE,StrongR,SharpZD,etal.Rapamycinfedlateinlife extends lifespaningeneticallyheterogeneousmice. Nature. 2009;460:392-6.
-
(2009)
Nature.
, vol.460
, pp. 392-396
-
-
Harrison, D.E.1
Strong, R.2
Sharp, Z.D.3
-
35
-
-
0038299000
-
Sirolimus:itsdiscovery,biologicalproperties,and mechanism ofaction
-
(Suppl)
-
Sehgal SN.Sirolimus:itsdiscovery,biologicalproperties,and mechanism ofaction. Transplant Proc. 2003;35(Suppl):7S-14S.
-
(2003)
Transplant Proc.
, vol.35
, pp. 7S-14S
-
-
Sehgal, S.N.1
-
38
-
-
0034988724
-
Endothelialcellhypertrophyinducedbyvascularendo-thelialgrowthfactorintheretina
-
HofmanP,vanBlijswijkBC,GaillardPJ,VrensenGFJM,Schlinge-mannRO.Endothelialcellhypertrophyinducedbyvascularendo-thelialgrowthfactorintheretina.Newinsightsintothepathogenesis of capillarynonperfusion. ArchOphthalmol. 2001;119:861-6.
-
(2001)
Newinsightsintothepathogenesis of Capillarynonperfusion. ArchOphthalmol.
, vol.119
, pp. 861-866
-
-
Hofman, P.1
Vanblijswijk, B.C.2
Gaillard, P.J.3
Vrensen, G.F.J.M.4
Schlinge-Mann, R.O.5
-
39
-
-
0035024082
-
Role ofVEGF-Ainendothelialphenotypicshiftinhumandiabetic retinopathy andVEGF-A-inducedretinopathyinmonkeys
-
Hofman P,BlaauwgeersHGT,VrensenGFJM,SchlingemannRO. Role ofVEGF-Ainendothelialphenotypicshiftinhumandiabetic retinopathy andVEGF-A-inducedretinopathyinmonkeys. Oph-thalmic Res. 2001;33:156-62.
-
(2001)
Oph-thalmic Res.
, vol.33
, pp. 156-162
-
-
Hofman, P.1
Blaauwgeers, H.G.T.2
Vrensen, G.F.J.M.3
Schlingemann, R.O.4
-
40
-
-
77953545224
-
Antiangio-genic effectsandtranscriptionalregulationofPEDFindiabetic retinopathy
-
Wang B,AthertonP,PatelR,ManningG,DonnellyR.Antiangio-genic effectsandtranscriptionalregulationofPEDFindiabetic retinopathy. Microvasc Res. 2010;80:31-6.
-
(2010)
Microvasc Res.
, vol.80
, pp. 31-36
-
-
Wang, B.1
Atherton, P.2
Patel, R.3
Manning, G.4
Donnelly, R.5
-
41
-
-
0037627630
-
Lowcontentofthenatural ocular anti-angiogenicagentpigmentepithelium-derivedfactor (PEDF) inaqueoushumorpredictsprogressionofdiabeticretinop-athy
-
Boehm BO,LangG,VolpertO,etal.Lowcontentofthenatural ocular anti-angiogenicagentpigmentepithelium-derivedfactor (PEDF) inaqueoushumorpredictsprogressionofdiabeticretinop-athy. Diabetologia. 2003;46:394-400.
-
(2003)
Diabetologia.
, vol.46
, pp. 394-400
-
-
Boehm, B.O.1
Lang, G.2
Volperto3
-
42
-
-
30344469077
-
High levelsofpigmentepithelium-derivedfactorintheretinaofa rat modeloftype2diabetes
-
Matsuoka M,OgataN,MinaminoK,HiguchiA,MatsumuraM. High levelsofpigmentepithelium-derivedfactorintheretinaofa rat modeloftype2diabetes. Exp EyeRes. 2006;82:172-8.
-
(2006)
Exp EyeRes.
, vol.82
, pp. 172-178
-
-
Matsuoka, M.1
Ogata, N.2
Minamino, K.3
Higuchi, A.4
Matsumura, M.5
-
43
-
-
79955970403
-
Rapamycininducedimpaired wound healingisassociatedwithcompromisedtissuelactate accumulation andextracellularmatrixremodeling
-
Weinreich J,LöbS,Löffler M,etal.Rapamycininducedimpaired wound healingisassociatedwithcompromisedtissuelactate accumulation andextracellularmatrixremodeling. Eur SurgRes. 2011;47:39-44.
-
(2011)
Eur SurgRes.
, vol.47
, pp. 39-44
-
-
Weinreich, J.1
Löbs2
Löffler, M.3
-
44
-
-
25444435486
-
Systemicrapamycininhibitsretinalandchoroidalneovasculariza-tion inmice
-
Dejneka NS,KurokiAM,FosnotJ,TangW,TolentinoMJ,Bennet J. Systemicrapamycininhibitsretinalandchoroidalneovasculariza-tion inmice. Mol Vis. 2004;10:964-72.
-
(2004)
Mol Vis.
, vol.10
, pp. 964-972
-
-
Dejneka, N.S.1
Kuroki, A.M.2
Fosnot, J.3
Tang, W.4
Tolentino, M.J.5
Bennet, J.6
-
45
-
-
84867830181
-
Therapeuticinterventions against inflammatory andangiogenicmediatorsinproliferative diabetic retinopathy
-
Gologorsky D,ThanosA,VavvasD.Therapeuticinterventions against inflammatory andangiogenicmediatorsinproliferative diabetic retinopathy. Mediators Inflamm. 2012;2012:629452.
-
(2012)
Mediators Inflamm.
, vol.2012
, pp. 629452
-
-
Gologorsky, D.1
Thanos, A.2
Vavvas, D.3
|