Procedures for mucosal immunization and analyses of cellular immune response to candidate HIV vaccines in murine and nonhuman primate models

Methods in Molecular Biology

Volumn 1184, Issue , 2014, Pages 417-455

  Singh, Shailbala ^a   Nehete, Pramod ^b   Hanley, Patrick ^b   Nehete, Bharti ^b   Yang, Guojun ^a   He, Hong ^a   Anthony, Scott M ^a   Schluns, Kimberly S ^a   Sastry, K Jagannadha ^a,b  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Animal models; Cytokine; ELISPOT; Flow cytometry; HIV AIDS; Mucosal immunity; Nonhuman primates; Rhesus macaques; T cells; Vaccines

Indexed keywords

CYTOKINE; HUMAN IMMUNODEFICIENCY VIRUS VACCINE;

ANTIGEN SPECIFICITY; ARTICLE; AUTOPSY; BIOPSY; BLOOD SAMPLING; BODY FLUID; BUCCAL BIOPSY; CELL ISOLATION; CELL STIMULATION; CELLULAR IMMUNITY; CHEEK; CHEMICAL ANALYSIS; COLON BIOPSY; DRUG ADMINISTRATION ROUTE; DUODENUM BIOPSY; ENRICHMENT CULTURE; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE GENITAL SYSTEM; FLOW CYTOMETRY; GYNECOLOGICAL EXAMINATION; HUMAN; IMMUNOASSAY; IMMUNOGENICITY; INTRACELLULAR CYTOKINE ANALYSIS; INTRADERMAL DRUG ADMINISTRATION; INTRATONSILLAR DRUG ADMINISTRATION; LUNG; LUNG LAVAGE; LYMPH NODE BIOPSY; LYMPHOID TISSUE; MACAQUE MODEL; MOUSE MODEL; MUCOSA; NASAL LAVAGE; NONHUMAN; PERCOLL GRADIENT ENRICHMENT; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIMATE MODEL; PRIORITY JOURNAL; RECTAL PINCH BIOPSY; RECTAL SECRETION; RECTUM; RECTUM BIOPSY; RHESUS MONKEY; STANDARDIZATION; STOMACH BIOPSY; T LYMPHOCYTE; TONSIL; TONSILLAR BIOPSY; UTERINE CERVIX BIOPSY; VACCINATION; VAGINAL PINCH BIOPSY; VAGINAL SECRETION; VIRUS TRANSMISSION; ANIMAL; CELL SEPARATION; FEMALE; HIV INFECTIONS; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNIZATION; IMMUNOLOGICAL PROCEDURES; IMMUNOLOGY; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; METABOLISM; MOUSE; PROCEDURES; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, INTRAVENOUS; ADMINISTRATION, TOPICAL; AIDS VACCINES; ANIMALS; BIOPSY; CELL SEPARATION; FEMALE; HIV; HIV INFECTIONS; HUMANS; IMMUNITY, CELLULAR; IMMUNIZATION; IMMUNOLOGIC TESTS; INJECTIONS, INTRAMUSCULAR; MACACA MULATTA; MICE; MUCOUS MEMBRANE; T-LYMPHOCYTES;

EID: 84925884032     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4939-1115-8_24     Document Type: Article

References (36)

1. Gamble LJ, Matthews QL (2010) Current progress in the development of a prophylactic vaccine for HIV-1. Drug Des Devel Ther 5: 9-26
2. Girard MP, Osmanov SK, Kieny MP (2006) A review of vaccine research and development: the human immunodefi ciency virus (HIV). Vaccine 19:4062-4081
3. Kim JH, Rerks-Ngarm S, Excler JL et al (2010) HIV vaccines: lessons learned and the way forward. Curr Opin HIV AIDS 5:428-3
4. Esparza J, Osmanov S (2003) HIV vaccines: a global perspective. Curr Mol Med 3:183-193
5. Hu SL (2005) Non-human primate models for AIDS vaccine research. Curr Drug Targets Infect Disord 2:193-201
6. Duerr A (2010) Update on mucosal HIV vaccine vectors. Curr Opin HIV AIDS 5:397-403
7. Nehete PN, Singh S, Sastry KJ (2013) Lessons on non-progression of HIV disease from monkeys. Front Immunol 4:64
8. Nehete PN, Nehete BP, Hill L et al (2008) Selective induction of cell-mediated immunity and protection of rhesus macaques from chronic SHIV(KU2) infection by prophylactic vaccination with a conserved HIV-1 envelope peptide-cocktail. Virology 370:130-141
9. Sastry KJ, Nehete PN, Venkatnarayanan S et al (1992) Rapid in vivo induction of HIV-specific CD8+ cytotoxic T lymphocytes by a 15-Amino acid unmodifi ed free peptide from the immunodominant V3-loop of GP120. Virology 188: 502-509
10. Weaver EA, Nehete PN, Nehete BP et al (2009) Protection against mucosal SHIV challenge by peptide and helper-dependent adenovirus vaccines. Viruses 1:920
11. Murphy KL, Baxter MG, Flecknell PA (2012) Anesthesia and analgesia in nonhuman primates. In: Abee CR, Mansfi eld K, Tardif SD et al (eds) Nonhuman primates in biomedical research: biology and management. Academic, San Diego, CA, pp 403-436
12. Popilskis SJ, Lee DR, Elmore DB (2011) Anesthesia and analgesia in nonhuman primates. In: Fish R, Danneman PJ, Brown M, Karas A (eds) Anesthesia and analgesia in laboratory animals. Academic, San Diego, CA, pp 335-363
13. Bellanti JA, Zeligs BJ, Mendez de Inocencio J et al (2001) Alternative routes of immunization for prevention of infectious diseases: a new paradigm for the 21st century. Allergy Asthma Proc 22:173-176
14. Scherliess R (2011) Delivery of antigens used for vaccination: recent advances and challenges. Ther Deliv 2:1351-1368
15. Meeusen EN (2011) Exploiting mucosal surfaces for the development of mucosal vaccines. Vaccine 29:8506-8511
16. Demberg T, Robert-Guroff M (2009) Mucosal immunity and protection against HIV/SIV infection: strategies and challenges for vaccine design. Int Rev Immunol 28:20-48
17. Pachuk CJ, McCallus DE, Weiner DB, Satishchandran C (2000) DNA vaccines- challenges in delivery. Curr Opin Mol Ther 2: 188-189
18. Dunn TB (1954) Normal and pathological anatomy of the reticular tissue in laboratory mice. J Natl Cancer Inst 14:1281-1434
19. Covelli V (2013) Guide to the necropsy of the mouse. http://eulep.pdn. cam.ac.uk/ Necropsy-of-The-Mouse. Accessed 28 July 2013
20. Reeves JP, Reeves PA (2001) Removal of lymphoid organs. Curr Protoc Immunol 1:1.9.1-1.9.3
21. Fuss IJ, Kanof ME, Smith PD, Zola H (2009) Isolation of whole mononuclear cells from peripheral blood and cord blood. Curr Protoc Immunol 85:7.1.1-7.1.8
22. Ulmer AJ, Scholz W, Ernst M et al (1984) Isolation and subfractionation of human peripheral blood mononuclear cells (PBMC) by density gradient centrifugation on Percoll. Immunobiology 166:238-250
23. Schluns KS, Nowak EC, Cabrera-Hernandez A et al (2004) Distinct cell types control lymphoid subset development by means of IL-15 and IL-15 receptor alpha expression. Proc Natl Acad Sci U S A 101:5616-5621
24. Sheridan BS, Lefrançois L (2012) Isolation of mouse lymphocytes from small intestine tissues. Curr Protoc Immunol 99:3.19.1-3.19.11
25. Seifter S, Gallop PM, Klein L et al (1959) Studies on collagen, part II. Properties of purifi ed collagenase and its inhibition. J Biol Chem 234:285
26. Koup RA, Douek DC (2011) Vaccine design for CD8 T lymphocyte responses. Cold Spring Harb Perspect Med 1(1):a007252. doi: 10.1101/ cshperspect.a007252
27. Appay V, Douek DC, Price DA (2008) CD8+ T cell effi cacy in vaccination and disease. Nat Med 14:623-628
28. Swain SL, McKinstry KK, Strutt TM (2012) Expanding roles for CD4+ T cells in immunity to viruses. Nat Rev Immunol 12:136-148
29. Perrin H, Canderan G, Sékaly RP, Trautmann L (2010) New approaches to design HIV-1Tcell vaccines. Curr Opin HIV AIDS 5: 368-376
30. Schmittel A, Keilholz U, Thiel E, Scheibenbogen C (2000) Quantification of tumor-specific T lymphocytes with the ELISPOT assay. J Immunother 23:289-295
31. De Rosa SC (2012) Vaccine applications of flow cytometry. Methods 57:383-391
32. Lehmann PV, Zhang W (2012) Unique strengths of ELISPOT for T cell diagnostics. Methods Mol Biol 792:3-23
33. Kalyuzhny AE (2005) Chemistry and biology of the ELISPOT assay. In: Kalyuzhny AE (ed) Handbook of ELISPOT: methods and protocols. Humana Press, Totowa, pp 15-31
34. Lehman PV (2005) Image analysis and data management of ELISPOT assay results. In: Kalyuzhny AE (ed) Handbook of ELISPOT: methods and protocols. Humana Press, Totowa, pp 117-132
35. Weaver EA, Nehete PN, Nehete BP et al (2013) Comparison of systemic and mucosal immunization with helper-dependent adenoviruses for vaccination against mucosal challenge with SHIV. PLoS One 8(7):e67574. doi: 10.1371/journal.pone. 0067574
36. Smith SG, Joosten SA, Verscheure V et al (2009) Identification of major factors infl uencing ELISpot-based monitoring of cellular responses to antigens from Mycobacterium tuberculosis . PLoS One 4(11):e7972. doi: 10.1371/ journal.pone.0007972