Blocking cold-inducible rna-binding protein protects liver from ischemia-reperfusion injury

Shock

Volumn 43, Issue 1, 2015, Pages 24-30

  Godwin, Andrew ^a   Yang, Weng Lang ^a,b   Sharma, Archna ^b   Khader, Adam ^a   Wang, Zhimin ^b   Zhang, Fangming ^b   Nicastro, Jeffrey ^a   Coppa, Gene F ^a   Wang, Ping ^a  

^a DONALD AND BARBARA ZUCKER SCHOOL OF MEDICINE AT HOFSTRA NORTHWELL   (United States)

^b FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

Author keywords

Apoptosis; CIRP; Hepatic ischemia reperfusion; Inflammation; Neutrophil infiltration; Nitrosative stress

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BLOCKING ANTIBODY; COLD INDUCIBLE RNA BINDING PROTEIN; COLD INDUCIBLE RNA BINDING PROTEIN ANTIBODY; COLD SHOCK PROTEIN; CYCLOOXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; LACTATE DEHYDROGENASE; LIVER PROTECTIVE AGENT; NEUTRALIZING ANTIBODY; NUCLEAR PROTEIN; POLYCLONAL ANTIBODY; RNA BINDING PROTEIN; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR INHIBITOR; UNCLASSIFIED DRUG; CIRBP PROTEIN, MOUSE;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONFERENCE PAPER; CONTROLLED STUDY; CYTOARCHITECTURE; INFLAMMATION; INTERNAL JUGULAR VEIN; LACTATE DEHYDROGENASE BLOOD LEVEL; LIVER CELL DAMAGE; LIVER ISCHEMIA; LIVER PROTECTION; MALE; MICROVASCULAR ISCHEMIA; MOUSE; NEUTROPHIL CHEMOTAXIS; NICK END LABELING; NITROSATIVE STRESS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SECRETION; REPERFUSION INJURY; SURVIVAL RATE; SURVIVAL TIME; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; LIVER; LIVER DISEASES; METABOLISM; PATHOLOGY;

ANIMALS; ANTIBODIES, NEUTRALIZING; APOPTOSIS; INTERLEUKIN-6; LIVER; LIVER DISEASES; MALE; MICE; REPERFUSION INJURY; RNA-BINDING PROTEINS;

EID: 84925850639     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0000000000000251     Document Type: Conference Paper

References (35)

1. Montalvo-Jave EE, Escalante-Tattersfield T, Ortega-Salgado JA, Pina E, Geller DA: Factors in the pathophysiology of the liver ischemia-reperfusion injury. J Surg Res 147(1):153-159, 2008.
2. Kuncewitch M, Yang WL, Molmenti E, Nicastro J, Coppa GF, Wang P: Wnt agonist attenuates liver injury and improves survival after hepatic ischemia/reperfusion. Shock 39(1):3-10, 2013.
3. Kupiec-Weglinski JW, Busuttil RW: Ischemia and reperfusion injury in liver transplantation. Transplant Proc 37(4):1653-1656, 2005.
4. Clavien PA, Selzner M, Rudiger HA, Graf R, Kadry Z, Rousson V, Jochum W: A prospective randomized study in 100 consecutive patients undergoing major liver resection with versus without ischemic preconditioning. Ann Surg 238(6): 843-850, 2003.
5. Petrowsky H, McCormack L, Trujillo M, Selzner M, Jochum W, Clavien PA: A prospective, randomized, controlled trial comparing intermittent portal triad clamping versus ischemic preconditioning with continuous clamping for major liver resection. Ann Surg 244(6):921-928, 2006.
6. van Golen RF, Reiniers MJ, Olthof PB, van Gulik TM, Heger M: Sterile inflammation in hepatic ischemia/reperfusion injury: present concepts and potential therapeutics. J Gastroenterol Hepatol 28(3):394-400, 2013.
7. Eltzschig HK, Eckle T: Ischemia and reperfusion-from mechanism to translation. Nat Med 17(11):1391-1401, 2011.
8. Kubes P, Mehal WZ: Sterile inflammation in the liver. Gastroenterology 143(5):1158-1172, 2012.
9. Ward PA: An endogenous factor mediates shock-induced injury. Nat Med 19(11):1368-1369, 2013.
10. Nishiyama H, Higashitsuji H, Yokoi H, Itoh K, Danno S, Matsuda T, Fujita J: Cloning and characterization of human CIRP (cold-inducible RNA-binding protein) cDNA and chromosomal assignment of the gene. Gene 204(1-2): 115-120, 1997.
11. Qiang X, Yang WL, Wu R, Zhou M, Jacob A, Dong W, Kuncewitch M, Ji Y, Yang H, Wang H, et al.: Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis. Nat Med 19(11): 1489-1495, 2013.
12. Zhou M, Yang WL, Ji Y, Qiang X, Wang P: Cold-inducible RNA-binding protein mediates neuroinflammation in cerebral ischemia. Biochim Biophys Acta 1840(7):2253-2261, 2014.
13. Rajayer SR, Jacob A, Yang WL, Zhou M, Chaung W, Wang P: Cold-inducible RNA-binding protein is an important mediator of alcohol-induced brain inflammation. PLoS One 8(11):e79430, 2013.
14. Matsuda A, Jacob A, Wu R, Zhou M, Aziz M, Wang P: Milk fat globuleVEGF factor VIII ameliorates liver injury after hepatic ischemia-reperfusion. J Surg Res 180(1):e37-e46, 2013.
15. Heijnen BH, Straatsburg IH, Gouma DJ, van Gulik TM: Decrease in core liver temperature with 10 degrees C by in situ hypothermic perfusion under total hepatic vascular exclusion reduces liver ischemia and reperfusion injury during partial hepatectomy in pigs. Surgery 134(5):806-817, 2003.
16. Desmet VJ, Knodell RG, Ishak KG, Black WC, Chen TS, Craig R, Kaplowitz N, Kiernan TW, Wollman J: Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. J Hepatol 38(4):382-386, 2003.
17. Behrends M, Martinez-Palli G, Niemann CU, Cohen S, Ramachandran R, Hirose R: Acute hyperglycemia worsens hepatic ischemia/reperfusion injury in rats. J Gastrointest Surg 14(3):528-535, 2010.
18. Nastos C, Kalimeris K, Papoutsidakis N, Tasoulis MK, Lykoudis PM, Theodoraki K, Nastou D, Smyrniotis V, Arkadopoulos N: Global consequences of liver ischemia/reperfusion injury. Oxid Med Cell Longev 2014:906965, 2014.
19. Fausto N, Campbell JS, Riehle KJ: Liver regeneration. J Hepatol 57(3): 692-694, 2012.
20. Pahlavan PS, Feldmann RE Jr, Zavos C, Kountouras J: Prometheus' challenge: molecular, cellular and systemic aspects of liver regeneration. J Surg Res 134(2):238-251, 2006.
21. van Golen RF, van Gulik TM, Heger M: The sterile immune response during hepatic ischemia/reperfusion. Cytokine Growth Factor Rev 23(3):69-84, 2012.
22. Tsung A, Klune JR, Zhang X, Jeyabalan G, Cao Z, Peng X, Stolz DB, Geller DA, Rosengart MR, Billiar TR: HMGB1 release induced by liver ischemia involves Toll-like receptor 4 dependent reactive oxygen species production and calcium-mediated signaling. J Exp Med 204(12):2913-2923, 2007.
23. O'Neill LAJ, Golenbock D, Bowie AG: The history of Toll-like receptorsVredefining innate immunity. Nat Rev Immunol 13(6):453-460, 2013.
24. Beutler BA: TLRs and innate immunity. Blood 113(7):1399-1407, 2009.
25. Howell J, Gow P, Angus P, Visvanathan K: Role of Toll-like receptors in liver transplantation. Liver Transpl 20(3):270-280, 2014.
26. Foell D, Wittkowski H, Roth J: Mechanisms of disease: a FDAMP view of inflammatory arthritis. Nat Clin Pract Rheumatol 3(7):382-390, 2007.
27. Brochu C, Cabrita MA, Melanson BD, Hamill JD, Lau R, Pratt MA, McKay BC: NF-kappaBYdependent role for cold-inducible RNA binding protein in regulating interleukin 1beta. PLoS One 8(2):e57426, 2013.
28. Varadarajan R, Golden-Mason L, Young L, McLoughlin P, Nolan N, McEntee G, Traynor O, Geoghegan J, Hegarty JE, O'Farrelly C: Nitric oxide in early ischaemia reperfusion injury during human orthotopic liver transplantation. Transplantation 78(2):250-256, 2004.
29. Pacher P, Beckman JS, Liaudet L: Nitric oxide and peroxynitrite in health and disease. Physiol Rev 87(1):315-424, 2007.
30. Lin FS, Shen SQ, Chen ZB, Yan RC: 17Beta-estradiol attenuates reduced-size hepatic ischemia/reperfusion injury by inhibition apoptosis via mitochondrial pathway in rats. Shock 37(2):183-190, 2012.
31. Datta G, Fuller BJ, Davidson BR: Molecular mechanisms of liver ischemia reper-fusion injury: insights from transgenic knockout models. World J Gastroenterol 19(11):1683-1698, 2013.
32. Klune JR, Tsung A: Molecular biology of liver ischemia/reperfusion injury: established mechanisms and recent advancements. Surg Clin North Am 90(4): 665-677, 2010.
33. Lu B, Wang C, Wang M, Li W, Chen F, Tracey KJ, Wang H: Molecular mechanism and therapeutic modulation of high mobility group box 1 release and action: an updated review. Expert Rev Clin Immunol 10(6):713-727, 2014.
34. Andersson U, Tracey KJ: HMGB1 is a therapeutic target for sterile inflammation and infection. Annu Rev Immunol 29:139-162, 2011.
35. Tsung A, Sahai R, Tanaka H, Nakao A, Fink MP, Lotze MT, Yang H, Li J, Tracey KJ, Geller DA, et al.: The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion. J Exp Med 201(7):1135-1143, 2005.