메뉴 건너뛰기




Volumn 44, Issue 2, 2015, Pages 302-310

The potential role of the glycoprotein osteoactivin/glycoprotein nonmetastatic melanoma protein b in pancreatic cancer

Author keywords

Apoptosis; GPNMB osteoactivin; Invasion; Pancreatic ductal adenocarcinoma; Proliferation

Indexed keywords

BROXURIDINE; FLUORESCEIN ISOTHIOCYANATE; GLYCOPROTEIN; GLYCOPROTEIN NONMETASTATIC MELANOMA PROTEIN B; LIPOCORTIN 5; MEMBRANE PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG; GPNMB PROTEIN, HUMAN;

EID: 84925848523     PISSN: 08853177     EISSN: 15364828     Source Type: Journal    
DOI: 10.1097/MPA.0000000000000250     Document Type: Article
Times cited : (11)

References (42)
  • 3
    • 77955715149 scopus 로고    scopus 로고
    • Treatment of pancreatic cancer with epidermal growth factor receptor-targeted therapy
    • Faller BA, Burtness B. Treatment of pancreatic cancer with epidermal growth factor receptor-targeted therapy. Biologics. 2009; 3: 419-428.
    • (2009) Biologics. , vol.3 , pp. 419-428
    • Faller, B.A.1    Burtness, B.2
  • 5
    • 34249933404 scopus 로고    scopus 로고
    • Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group
    • Moore MJ, Goldstein D, Hamm J, et al. Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J ClinOncol. 2007; 25: 1960-1966.
    • (2007) J ClinOncol. , vol.25 , pp. 1960-1966
    • Moore, M.J.1    Goldstein, D.2    Hamm, J.3
  • 6
    • 0028927442 scopus 로고
    • Nmb, a novel gene, is expressed in low-metastatic human melanoma cell lines and xenografts
    • Weterman MA, Ajubi N, van Dinter IM, et al. nmb, a novel gene, is expressed in low-metastatic human melanoma cell lines and xenografts. Int J Cancer. 1995; 60: 73-81.
    • (1995) Int J Cancer. , vol.60 , pp. 73-81
    • Weterman, M.A.1    Ajubi, N.2    Van Dinter, I.M.3
  • 7
    • 77957809884 scopus 로고    scopus 로고
    • ADAM10 releases a soluble form of the GPNMB/osteoactivin extracellular domain with angiogenic properties
    • Rose AA, Annis MG, Dong Z, et al. ADAM10 releases a soluble form of the GPNMB/osteoactivin extracellular domain with angiogenic properties. PLoS One. 2010; 5: e12093.
    • (2010) PLoS One. , vol.5 , pp. e12093
    • Rose, A.A.1    Annis, M.G.2    Dong, Z.3
  • 8
    • 77955021117 scopus 로고    scopus 로고
    • DC-HIL/glycoprotein Nmb promotes growth of melanoma in mice by inhibiting the activation of tumor-reactive T cells
    • Tomihari M, Chung JS, Akiyoshi H, et al. DC-HIL/glycoprotein Nmb promotes growth of melanoma in mice by inhibiting the activation of tumor-reactive T cells. Cancer Res. 2010; 70: 5778-5787.
    • (2010) Cancer Res. , vol.70 , pp. 5778-5787
    • Tomihari, M.1    Chung, J.S.2    Akiyoshi, H.3
  • 9
    • 33644747384 scopus 로고    scopus 로고
    • CR011, a fully human monoclonal antibody-auristatin e conjugate, for the treatment of melanoma
    • Tse KF, Jeffers M, Pollack VA, et al. CR011, a fully human monoclonal antibody-auristatin E conjugate, for the treatment of melanoma. Clin Cancer Res. 2006; 12: 1373-1382.
    • (2006) Clin Cancer Res. , vol.12 , pp. 1373-1382
    • Tse, K.F.1    Jeffers, M.2    Pollack, V.A.3
  • 10
    • 77952237462 scopus 로고    scopus 로고
    • GPNMB expression in uveal melanoma: A potential for targeted therapy
    • Williams MD, Esmaeli B, Soheili A, et al. GPNMB expression in uveal melanoma: a potential for targeted therapy. Melanoma Res. 2010; 20: 184-190.
    • (2010) Melanoma Res. , vol.20 , pp. 184-190
    • Williams, M.D.1    Esmaeli, B.2    Soheili, A.3
  • 11
    • 33646230317 scopus 로고    scopus 로고
    • Glycoprotein nonmetastatic melanoma protein B, a potential molecular therapeutic target in patients with glioblastoma multiforme
    • Kuan CT, Wakiya K, Dowell JM, et al. Glycoprotein nonmetastatic melanoma protein B, a potential molecular therapeutic target in patients with glioblastoma multiforme. Clin Cancer Res. 2006; 12: 1970-1982.
    • (2006) Clin Cancer Res. , vol.12 , pp. 1970-1982
    • Kuan, C.T.1    Wakiya, K.2    Dowell, J.M.3
  • 12
    • 0242690379 scopus 로고    scopus 로고
    • Osteoactivin expressed during cirrhosis development in rats fed a choline-deficient, L-amino acid-defined diet, accelerates motility of hepatoma cells
    • Onaga M, Ido A, Hasuike S, et al. Osteoactivin expressed during cirrhosis development in rats fed a choline-deficient, L-amino acid-defined diet, accelerates motility of hepatoma cells. J Hepatol. 2003; 39: 779-785.
    • (2003) J Hepatol. , vol.39 , pp. 779-785
    • Onaga, M.1    Ido, A.2    Hasuike, S.3
  • 13
    • 84879639061 scopus 로고    scopus 로고
    • Upregulation of glycoprotein nonmetastaticB by colony-stimulating factor-1 and epithelial cell adhesion molecule in hepatocellular carcinoma cells
    • Tian F, Liu C, Wu Q, et al.Upregulation of glycoprotein nonmetastaticB by colony-stimulating factor-1 and epithelial cell adhesion molecule in hepatocellular carcinoma cells. Oncol Res. 2013; 20: 341-350.
    • (2013) Oncol Res. , vol.20 , pp. 341-350
    • Tian, F.1    Liu, C.2    Wu, Q.3
  • 14
    • 84905321759 scopus 로고    scopus 로고
    • Novel genes associated with colorectal cancer are revealed by high resolution cytogenetic analysis in a patient specific manner
    • Eldai H, Periyasamy S, Al Qarni S, et al. Novel genes associated with colorectal cancer are revealed by high resolution cytogenetic analysis in a patient specific manner. PLoS One. 2013; 8: e76251.
    • (2013) PLoS One. , vol.8 , pp. e76251
    • Eldai, H.1    Periyasamy, S.2    Al Qarni, S.3
  • 15
    • 84880109599 scopus 로고    scopus 로고
    • Glycoprotein non-metastatic b (GPNMB): Ametastaticmediator and emerging therapeutic target in cancer
    • Maric G, Rose AA, Annis MG, et al. Glycoprotein non-metastatic b (GPNMB): ametastaticmediator and emerging therapeutic target in cancer. Onco Targets Ther. 2013; 6: 839-852.
    • (2013) Onco Targets Ther. , vol.6 , pp. 839-852
    • Maric, G.1    Rose, A.A.2    Annis, M.G.3
  • 16
    • 77950670628 scopus 로고    scopus 로고
    • Glycoprotein nonmetastatic B is an independent prognostic indicator of recurrence and a novel therapeutic target in breast cancer
    • Rose AA, Grosset AA, Dong Z, et al. Glycoprotein nonmetastatic B is an independent prognostic indicator of recurrence and a novel therapeutic target in breast cancer. Clin Cancer Res. 2010; 16: 2147-2156.
    • (2010) Clin Cancer Res. , vol.16 , pp. 2147-2156
    • Rose, A.A.1    Grosset, A.A.2    Dong, Z.3
  • 17
    • 77950670628 scopus 로고    scopus 로고
    • Glycoprotein nonmetastatic B is an independent prognostic indicator of recurrence and a novel therapeutic target in breast cancer
    • Rose AAN, Grosset AA, Dong ZF, et al. Glycoprotein nonmetastatic B is an independent prognostic indicator of recurrence and a novel therapeutic target in breast cancer. Clin Cancer Res. 2010; 16: 2147-2156.
    • (2010) Clin Cancer Res. , vol.16 , pp. 2147-2156
    • Aan, R.1    Grosset, A.A.2    Dong, Z.F.3
  • 18
    • 43649099521 scopus 로고    scopus 로고
    • Pharmacologically enhanced expression of GPNMB increases the sensitivity of melanoma cells to the CR011-vcMMAE antibody-drug conjugate
    • Qian XZ, Mills E, Torgov M, et al. Pharmacologically enhanced expression of GPNMB increases the sensitivity of melanoma cells to the CR011-vcMMAE antibody-drug conjugate. Mol Oncol. 2008; 2: 81-93.
    • (2008) Mol Oncol. , vol.2 , pp. 81-93
    • Qian, X.Z.1    Mills, E.2    Torgov, M.3
  • 19
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001; 29: e45.
    • (2001) Nucleic Acids Res. , vol.29 , pp. e45
    • Pfaffl, M.W.1
  • 20
    • 84880869807 scopus 로고    scopus 로고
    • The complexity of NF-kappaB signaling in inflammation and cancer
    • Hoesel B, Schmid JA. The complexity of NF-kappaB signaling in inflammation and cancer. Mol Cancer. 2013; 12: 86.
    • (2013) Mol Cancer. , vol.12 , pp. 86
    • Hoesel, B.1    Schmid, J.A.2
  • 21
    • 84920035203 scopus 로고    scopus 로고
    • Role of WWOX and NF-kappaB in lung cancer progression
    • Chen S-J, Huang S-S, Chang N-S. Role of WWOX and NF-kappaB in lung cancer progression. Transl Respir Med. 2013; 1(1): 15.
    • (2013) Transl Respir Med. , vol.1 , Issue.1 , pp. 15
    • Chen, S.-J.1    Huang, S.-S.2    Chang, N.-S.3
  • 22
    • 85039888256 scopus 로고    scopus 로고
    • Effect of GPNMB on proliferation, apoptosis and invasion of human hepatoma cells
    • Zhang CY, Xie X, Zhang CX. Effect of GPNMB on proliferation, apoptosis and invasion of human hepatoma cells. Chin J Pathophysiol. 2013; 29: 1441-1446.
    • (2013) Chin J Pathophysiol. , vol.29 , pp. 1441-1446
    • Zhang, C.Y.1    Xie, X.2    Zhang, C.X.3
  • 23
    • 84872480731 scopus 로고    scopus 로고
    • C-FLIP, a master anti-apoptotic regulator
    • Safa AR. c-FLIP, a master anti-apoptotic regulator. Exp Oncol. 2012; 34: 176-184.
    • (2012) Exp Oncol. , vol.34 , pp. 176-184
    • Safa, A.R.1
  • 24
    • 40449136380 scopus 로고    scopus 로고
    • Targeting IAP (inhibitor of apoptosis) proteins for therapeutic intervention in tumors
    • Vucic D. Targeting IAP (inhibitor of apoptosis) proteins for therapeutic intervention in tumors. Curr Cancer Drug Targets. 2008; 8: 110-117.
    • (2008) Curr Cancer Drug Targets. , vol.8 , pp. 110-117
    • Vucic, D.1
  • 25
    • 79952708318 scopus 로고    scopus 로고
    • Caspase-8 and bid: Caught in the act between death receptors and mitochondria
    • Kantari C, Walczak H. Caspase-8 and bid: caught in the act between death receptors and mitochondria. Biochim Biophys Acta. 2011; 1813: 558-563.
    • (2011) Biochim Biophys Acta. , vol.1813 , pp. 558-563
    • Kantari, C.1    Walczak, H.2
  • 26
    • 84856698334 scopus 로고    scopus 로고
    • BCL2A1: The underdog in the BCL2 family
    • Vogler M. BCL2A1: the underdog in the BCL2 family. Cell Death Differ. 2012; 19: 67-74.
    • (2012) Cell Death Differ. , vol.19 , pp. 67-74
    • Vogler, M.1
  • 27
    • 0038521296 scopus 로고    scopus 로고
    • Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model
    • Rich JN, Shi Q, Hjelmeland M, et al. Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model. J Biol Chem. 2003; 278: 15951-15957.
    • (2003) J Biol Chem. , vol.278 , pp. 15951-15957
    • Rich, J.N.1    Shi, Q.2    Hjelmeland, M.3
  • 28
    • 84896494492 scopus 로고    scopus 로고
    • GPNMB/OA protein increases the invasiveness of human metastatic prostate cancer cell lines DU145 and PC3 through MMP-2 and MMP-9 activity
    • Fiorentini C, Bodei S, Bedussi F, et al. GPNMB/OA protein increases the invasiveness of human metastatic prostate cancer cell lines DU145 and PC3 through MMP-2 and MMP-9 activity. Exp Cell Res. 2014; 323: 100-111.
    • (2014) Exp Cell Res. , vol.323 , pp. 100-111
    • Fiorentini, C.1    Bodei, S.2    Bedussi, F.3
  • 29
    • 36849076668 scopus 로고    scopus 로고
    • Osteoactivin fragments produced by ectodomain shedding induce MMP-3 expression via ERK pathway in mouse NIH-3 T3 fibroblasts
    • Furochi H, Tamura S, MameokaM, et al. Osteoactivin fragments produced by ectodomain shedding induce MMP-3 expression via ERK pathway in mouse NIH-3 T3 fibroblasts. FEBS Lett. 2007; 581: 5743-5750.
    • (2007) FEBS Lett. , vol.581 , pp. 5743-5750
    • Furochi, H.1    Mameokam, T.S.2
  • 30
    • 0030744988 scopus 로고    scopus 로고
    • Identification of promoter activity and differential expression of transcripts encoding the murine stromelysin-1 gene in renal cells
    • Yee J, Kuncio GS, Bhandari B, et al. Identification of promoter activity and differential expression of transcripts encoding the murine stromelysin-1 gene in renal cells. Kidney Int. 1997; 52: 120-129.
    • (1997) Kidney Int. , vol.52 , pp. 120-129
    • Yee, J.1    Kuncio, G.S.2    Bhandari, B.3
  • 31
    • 33846048058 scopus 로고    scopus 로고
    • Transcription factors control invasion: AP-1 the first among equals
    • Ozanne BW, Spence HJ, McGarry LC, et al. Transcription factors control invasion: AP-1 the first among equals. Oncogene. 2007; 26: 1-10.
    • (2007) Oncogene. , vol.26 , pp. 1-10
    • Ozanne, B.W.1    Spence, H.J.2    McGarry, L.C.3
  • 32
    • 0032943591 scopus 로고    scopus 로고
    • The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells
    • Wang WX, Abbruzzese JL, Evans DB, et al. The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells. Clin Cancer Res. 1999; 5: 119-127.
    • (1999) Clin Cancer Res. , vol.5 , pp. 119-127
    • Wang, W.X.1    Abbruzzese, J.L.2    Evans, D.B.3
  • 33
    • 1842850737 scopus 로고    scopus 로고
    • Increased expression of NF-kappa B subunits in human pancreatic cancer cells
    • Chandler NM, Canete JJ, Callery MP. Increased expression of NF-kappa B subunits in human pancreatic cancer cells. J Surg Res. 2004; 118: 9-14.
    • (2004) J Surg Res. , vol.118 , pp. 9-14
    • Chandler, N.M.1    Canete, J.J.2    Callery, M.P.3
  • 34
    • 0037780982 scopus 로고    scopus 로고
    • Mitogenic and antiapoptotic role of constitutive NF-kappaB/Rel activity in pancreatic cancer
    • Liptay S, Weber CK, Ludwig L, et al. Mitogenic and antiapoptotic role of constitutive NF-kappaB/Rel activity in pancreatic cancer. Int J Cancer. 2003; 105: 735-746.
    • (2003) Int J Cancer. , vol.105 , pp. 735-746
    • Liptay, S.1    Weber, C.K.2    Ludwig, L.3
  • 35
    • 0346993732 scopus 로고    scopus 로고
    • Identification and characterization of the genes encoding human and mouse osteoactivin
    • Owen TA, Smock SL, Prakash S, et al. Identification and characterization of the genes encoding human and mouse osteoactivin. Crit Rev Eukaryot Gene Expr. 2003; 13: 205-220.
    • (2003) Crit Rev Eukaryot Gene Expr. , vol.13 , pp. 205-220
    • Owen, T.A.1    Smock, S.L.2    Prakash, S.3
  • 36
    • 34248226374 scopus 로고    scopus 로고
    • Gpnmb is induced in macrophages by IFN-gamma and lipopolysaccharide and acts as a feedback regulator of proinflammatory responses
    • Ripoll VM, Irvine KM, Ravasi T, et al. Gpnmb is induced in macrophages by IFN-gamma and lipopolysaccharide and acts as a feedback regulator of proinflammatory responses. J Immunol. 2007; 178: 6557-6566.
    • (2007) J Immunol. , vol.178 , pp. 6557-6566
    • Ripoll, V.M.1    Irvine, K.M.2    Ravasi, T.3
  • 37
    • 0037631651 scopus 로고    scopus 로고
    • MRNA expression of the murine glycoprotein (transmembrane) nmb (Gpnmb) gene is linked to the developing retinal pigment epithelium and iris
    • Bachner D, Schroder D, Gross G. mRNA expression of the murine glycoprotein (transmembrane) nmb (Gpnmb) gene is linked to the developing retinal pigment epithelium and iris. Brain Res Gene Expr Patterns. 2002; 1: 159-165.
    • (2002) Brain Res Gene Expr Patterns. , vol.1 , pp. 159-165
    • Bachner, D.1    Schroder, D.2    Gross, G.3
  • 38
    • 84863745351 scopus 로고    scopus 로고
    • Gpnmb/osteoactivin, an attractive target in cancer immunotherapy
    • Zhou LT, Liu FY, Li Y, et al. Gpnmb/osteoactivin, an attractive target in cancer immunotherapy. Neoplasma. 2012; 59: 1-5.
    • (2012) Neoplasma. , vol.59 , pp. 1-5
    • Zhou, L.T.1    Liu, F.Y.2    Li, Y.3
  • 39
    • 59349101632 scopus 로고    scopus 로고
    • A phase I/II study of CR011-vcMMAE, an antibody toxin conjugate drug, in patients with unresectable stage III/IV melanoma
    • Hwu P, Sznol M, Kluger H, et al. A phase I/II study of CR011-vcMMAE, an antibody toxin conjugate drug, in patients with unresectable stage III/IV melanoma. J Clin Oncol. 2008; 26: 9029.
    • (2008) J Clin Oncol. , vol.26 , pp. 9029
    • Hwu, P.1    Sznol, M.2    Kluger, H.3
  • 40
    • 77950819962 scopus 로고    scopus 로고
    • A phase (Ph) I/II study of CR011-VcMMAE, an antibody-drug conjugate, in patients (Pts) with locally advanced or metastatic breast cancer (MBC)
    • Burris H, Saleh M, Bendell J, et al. A phase (Ph) I/II study of CR011-VcMMAE, an antibody-drug conjugate, in patients (Pts) with locally advanced or metastatic breast cancer (MBC). Cancer Res. 2009; 69: 855s-855s.
    • (2009) Cancer Res. , vol.69 , pp. 855s-855s
    • Burris, H.1    Saleh, M.2    Bendell, J.3
  • 41
    • 77952239035 scopus 로고    scopus 로고
    • A phase I/II study of CR011-vcMMAE, an antibody-drug conjugate (ADC) targeting glycoprotein NMB (GPNMB) in patients (pts) with advanced melanoma
    • Hwu P, SznolM, Pavlick A, et al. A phase I/II study of CR011-vcMMAE, an antibody-drug conjugate (ADC) targeting glycoprotein NMB (GPNMB) in patients (pts) with advanced melanoma. J Clin Oncol. 2009; 27: 9032.
    • (2009) J Clin Oncol. , vol.27 , pp. 9032
    • Hwu, P.1    Sznolm Pavlick, A.2
  • 42
    • 75149134295 scopus 로고    scopus 로고
    • A phase I/II study of CR011-vcMMAE, an antibody-drug conjugate, in patients (pts) with locally advanced or metastatic breast cancer (MBC)
    • Peacock N, Saleh M, Bendell J, et al. A phase I/II study of CR011-vcMMAE, an antibody-drug conjugate, in patients (pts) with locally advanced or metastatic breast cancer (MBC). J Clin Oncol. 2009; 27: 1067.
    • (2009) J Clin Oncol. , vol.27 , pp. 1067
    • Peacock, N.1    Saleh, M.2    Bendell, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.