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Volumn 32, Issue 10, 2014, Pages 1945-1958

A systematic review of calciumchannel blocker use and cognitive decline/dementia in the elderly

Author keywords

Aged; Alzheimer's disease; Calcium channel blockers; Cognitive disorders; Dementia

Indexed keywords

ANTIHYPERTENSIVE AGENT; CALCIUM CHANNEL BLOCKING AGENT;

EID: 84925826912     PISSN: 02636352     EISSN: 14735598     Source Type: Journal    
DOI: 10.1097/HJH.0000000000000273     Document Type: Review
Times cited : (46)

References (55)
  • 2
    • 67649803272 scopus 로고    scopus 로고
    • The effect of age on the association between blood pressure and cognitive function later in life
    • Euser S, Bemmel T, Schram M, Gussekloo J, Hofman A, Westendorp R, Breteler M. The effect of age on the association between blood pressure and cognitive function later in life. JAGS 2009; 57:1223-1237.
    • (2009) JAGS , vol.57 , pp. 1223-1237
    • Euser, S.1    Bemmel, T.2    Schram, M.3    Gussekloo, J.4    Hofman, A.5    Westendorp, R.6    Breteler, M.7
  • 3
    • 60949108829 scopus 로고    scopus 로고
    • Blood pressure and the risk for dementia-a double edged sword
    • Kennelly S, Lawlor B, Kenny R. Blood pressure and the risk for dementia-a double edged sword. Ageing Res Rev 2009; 8:61-70.
    • (2009) Ageing Res Rev , vol.8 , pp. 61-70
    • Kennelly, S.1    Lawlor, B.2    Kenny, R.3
  • 5
    • 84855967078 scopus 로고    scopus 로고
    • Immediate and late benefits of treating very elderly people with hypertension: Results from active treatment extension to hypertension in the very elderly randomised controlled trial
    • Beckett N, Peters R, Tuomilehto J, Swift C, Sever P, Potter J, et al. Immediate and late benefits of treating very elderly people with hypertension: results from active treatment extension to hypertension in the very elderly randomised controlled trial. BMJ 2012; 344:d7541.
    • (2012) BMJ , vol.344 , pp. d7541
    • Beckett, N.1    Peters, R.2    Tuomilehto, J.3    Swift, C.4    Sever, P.5    Potter, J.6
  • 6
    • 0032779103 scopus 로고    scopus 로고
    • Cognitive decline in individuals with high blood pressure: A longitudinal study in the elderly
    • For the EVA study group
    • Tzourio C, Dufouil C, Ducimetiére P, Alpérovitch A, for the EVA study group. Cognitive decline in individuals with high blood pressure: a longitudinal study in the elderly. Neurology 1999; 53:1948-1952.
    • (1999) Neurology , vol.53 , pp. 1948-1952
    • Tzourio, C.1    Dufouil, C.2    Ducimetiére, P.3    Alpérovitch, A.4
  • 8
    • 0029617996 scopus 로고
    • The association between midlife blood pressure levels and late-life cognitive function
    • Launer L, Masaki K, Petrovitch H, Foley D, Havlik R. The association between midlife blood pressure levels and late-life cognitive function. JAMA 1995; 274:1846-1851.
    • (1995) JAMA , vol.274 , pp. 1846-1851
    • Launer, L.1    Masaki, K.2    Petrovitch, H.3    Foley, D.4    Havlik, R.5
  • 9
    • 0027453765 scopus 로고
    • Untreated blood pressure level is inversely related to cognitive functioning: The Framingham study
    • Elias M, Wolf P, D'Agostino R, Cobb J, White L. Untreated blood pressure level is inversely related to cognitive functioning: the Framingham study. Am J Epidemiol 1993; 138:353-364.
    • (1993) Am J Epidemiol , vol.138 , pp. 353-364
    • Elias, M.1    Wolf, P.2    D'agostino, R.3    Cobb, J.4    White, L.5
  • 10
    • 0031951913 scopus 로고    scopus 로고
    • Hypertension is related to cognitive impairment. A 20-year follow-up of 999 men
    • Kilander L, Nyman H, Boberg M, Hansson L, Lithell H. Hypertension is related to cognitive impairment. A 20-year follow-up of 999 men. Hypertension 1998; 31:780-786.
    • (1998) Hypertension , vol.31 , pp. 780-786
    • Kilander, L.1    Nyman, H.2    Boberg, M.3    Hansson, L.4    Lithell, H.5
  • 11
    • 46949106968 scopus 로고    scopus 로고
    • Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): A double-blind, placebo-controlled trial
    • Peters R, Beckett N, Forette F, Tuomilehto J, Clarke R, Ritchie C, et al. Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo-controlled trial. Lancet Neurol 2008; 7:683-689.
    • (2008) Lancet Neurol , vol.7 , pp. 683-689
    • Peters, R.1    Beckett, N.2    Forette, F.3    Tuomilehto, J.4    Clarke, R.5    Ritchie, C.6
  • 12
    • 14844291328 scopus 로고    scopus 로고
    • Does blood pressure lowering treatment prevent dementia or cognitive decline in patients with cardiovascular and cerebrovascular disease?
    • Feigin V, Ratnasabapathy Y, Anderson C. Does blood pressure lowering treatment prevent dementia or cognitive decline in patients with cardiovascular and cerebrovascular disease? J Neurol Sci 2005; 229:151-155.
    • (2005) J Neurol Sci , vol.229 , pp. 151-155
    • Feigin, V.1    Ratnasabapathy, Y.2    Anderson, C.3
  • 13
    • 74949089743 scopus 로고    scopus 로고
    • Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive decline and dementia
    • McGuiness B, Todd S, Passmore P, Bullok R. Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive decline and dementia. Cochrane Database Syst Rev 2009; CD004034.
    • (2009) Cochrane Database Syst Rev , pp. CD004034
    • McGuiness, B.1    Todd, S.2    Passmore, P.3    Bullok, R.4
  • 14
    • 71749121407 scopus 로고    scopus 로고
    • Does use of antihypertensive drugs affect the incidence or progression of dementia? A systematic review
    • Shah K, Qureshi S, Johnson M, Parikh N, Schulz P, Kunik M. Does use of antihypertensive drugs affect the incidence or progression of dementia? A systematic review. Am J Geriatr Pharmacother 2009; 7:v250-v261.
    • (2009) Am J Geriatr Pharmacother , vol.7 , pp. v250-v261
    • Shah, K.1    Qureshi, S.2    Johnson, M.3    Parikh, N.4    Schulz, P.5    Kunik, M.6
  • 15
    • 70349441095 scopus 로고    scopus 로고
    • Prevention of dementia by antihypertensive drugs: How AT1-receptor-blockers and dihydropyridines better prevent dementia in hypertensive patients than thiazides and ACE-inhibitors
    • Fournier A, Oprisiu-Fournier R, Serot J, Godefroy O, Achard J, Faure S, et al. Prevention of dementia by antihypertensive drugs: how AT1-receptor-blockers and dihydropyridines better prevent dementia in hypertensive patients than thiazides and ACE-inhibitors. Expert Rev Neurother 2009; 9:1413-1431.
    • (2009) Expert Rev Neurother , vol.9 , pp. 1413-1431
    • Fournier, A.1    Oprisiu-Fournier, R.2    Serot, J.3    Godefroy, O.4    Achard, J.5    Faure, S.6
  • 16
    • 0032564132 scopus 로고    scopus 로고
    • Prevention of dementia in a randomised double-blind placebocontrolled systolic hypertension in Europe (SYST-EUR) trial
    • Forette F, Seux M, Staessen J, Thijs L, Birkenhäger W, Babarskiene MR, et al. Prevention of dementia in a randomised double-blind placebocontrolled systolic hypertension in Europe (SYST-EUR) trial. Lancet 1998; 352:1347-1351.
    • (1998) Lancet , vol.352 , pp. 1347-1351
    • Forette, F.1    Seux, M.2    Staessen, J.3    Thijs, L.4    Birkenhäger, W.5    Babarskiene, M.R.6
  • 17
    • 0037078312 scopus 로고    scopus 로고
    • The prevention of dementia with antihypertensive treatment
    • Systolic hypertension in Europe investigators
    • Forette F, Seux M, Staessen J, Thijs L, Babarskiene M, Babeanu S, et al. Systolic hypertension in Europe investigators. The prevention of dementia with antihypertensive treatment. Arch Int Med 2002; 162: 2046-2052.
    • (2002) Arch Int Med , vol.162 , pp. 2046-2052
    • Forette, F.1    Seux, M.2    Staessen, J.3    Thijs, L.4    Babarskiene, M.5    Babeanu, S.6
  • 18
    • 0033034786 scopus 로고    scopus 로고
    • Inhibition of excessive neuronal apoptosis by the calcium antagonist amlodipine and antioxidents in cerebellar granule cells
    • Mason R, Leeds P, Jacob R, Hough C, Zhang K, Mason P, et al. Inhibition of excessive neuronal apoptosis by the calcium antagonist amlodipine and antioxidents in cerebellar granule cells. J Neurochem 1999; 72:1448-1456.
    • (1999) J Neurochem , vol.72 , pp. 1448-1456
    • Mason, R.1    Leeds, P.2    Jacob, R.3    Hough, C.4    Zhang, K.5    Mason, P.6
  • 19
    • 56549130363 scopus 로고    scopus 로고
    • Nimodipine and its use in cerebrovascular disease: Evidence from recent preclinical and controlled clinical trials
    • Tomassioni D, Lanari A, Silvestrelli G, Traini E, Amenta F. Nimodipine and its use in cerebrovascular disease: evidence from recent preclinical and controlled clinical trials. Clin Exp Hypertens 2008; 30:744-766.
    • (2008) Clin Exp Hypertens , vol.30 , pp. 744-766
    • Tomassioni, D.1    Lanari, A.2    Silvestrelli, G.3    Traini, E.4    Amenta, F.5
  • 20
    • 37549044212 scopus 로고    scopus 로고
    • Use of calcium antagonists and cognitive decline in old age. The Leiden 85-plus study
    • Trompet S, Westendorp R, Kamper A, Craen A. Use of calcium antagonists and cognitive decline in old age. The Leiden 85-plus study. Neurobiol Aging 2008; 29:306-308.
    • (2008) Neurobiol Aging , vol.29 , pp. 306-308
    • Trompet, S.1    Westendorp, R.2    Kamper, A.3    Craen, A.4
  • 21
    • 77955013561 scopus 로고    scopus 로고
    • Cognitive functioning and antihypertensive treatment in the elderly: A 6-year follow-up study
    • Paran E, Anson O, Lowenthal D. Cognitive functioning and antihypertensive treatment in the elderly: a 6-year follow-up study. Am J Ther 2010; 17:358-364.
    • (2010) Am J Ther , vol.17 , pp. 358-364
    • Paran, E.1    Anson, O.2    Lowenthal, D.3
  • 22
    • 0033533468 scopus 로고    scopus 로고
    • Calcium-channel blockers and cognitive function in elderly people: Results from the Canadian study of health and aging
    • Maxwell C, Hogan D, Ebly E. Calcium-channel blockers and cognitive function in elderly people: results from the Canadian study of health and aging. CMAJ 1999; 161:501-506.
    • (1999) CMAJ , vol.161 , pp. 501-506
    • Maxwell, C.1    Hogan, D.2    Ebly, E.3
  • 23
    • 70449851433 scopus 로고    scopus 로고
    • Reappraisal of European guidelines on hypertension management: A European Society of Hypertension Task Force document
    • Mancia G, Laurent S, Agabiti-Rosei E, Ambrosioni E, Burnier M, Caulfield M, et al. Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document. J Hypertens 2009; 27:2121-2158.
    • (2009) J Hypertens , vol.27 , pp. 2121-2158
    • Mancia, G.1    Laurent, S.2    Agabiti-Rosei, E.3    Ambrosioni, E.4    Burnier, M.5    Caulfield, M.6
  • 24
    • 84899658037 scopus 로고    scopus 로고
    • The 2014 Canadian hypertension education rrogram recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension
    • Dasgupta K, Quinn R, Zamke K, Rabi D, Ravani P, Daskalopoulou S, et al. The 2014 Canadian hypertension education rrogram recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension. Can J Cardiol 2014; 30:485-501.
    • (2014) Can J Cardiol , vol.30 , pp. 485-501
    • Dasgupta, K.1    Quinn, R.2    Zamke, K.3    Rabi, D.4    Ravani, P.5    Daskalopoulou, S.6
  • 25
    • 77952304034 scopus 로고    scopus 로고
    • The japanese society of hypertension committee. The Japanese society of hypertension guidelines for the management of hypertension (JSH 2009)
    • Ogihara T, Kikuchi K, Matsuoka H, Fujita T, Higaki J, Horiuchi M, et al., The Japanese Society of Hypertension Committee. The Japanese society of hypertension guidelines for the management of hypertension (JSH 2009). Hypertens Res 2009; 32:3-107.
    • (2009) Hypertens Res , vol.32 , pp. 3-107
    • Ogihara, T.1    Kikuchi, K.2    Matsuoka, H.3    Fujita, T.4    Higaki, J.5    Horiuchi, M.6
  • 26
    • 77958128138 scopus 로고    scopus 로고
    • 2010 guidelines of the Taiwan Society of Cardiology for the management of hypertension
    • Chiang C, Wang T, Li Y, Lin T, Chien K, Yeh H, et al. 2010 guidelines of the Taiwan Society of Cardiology for the management of hypertension. J Formos Med Assoc 2010; 109:740-773.
    • (2010) J Formos Med Assoc , vol.109 , pp. 740-773
    • Chiang, C.1    Wang, T.2    Li, Y.3    Lin, T.4    Chien, K.5    Yeh, H.6
  • 27
    • 84862652155 scopus 로고    scopus 로고
    • 2010 Chinese guidelines for the management of hypertension
    • Liu L. 2010 Chinese guidelines for the management of hypertension. Chin J Cardiol 2011; 39:579-616.
    • (2011) Chin J Cardiol , vol.39 , pp. 579-616
    • Liu, L.1
  • 29
    • 84255169913 scopus 로고    scopus 로고
    • South African hypertension guideline 2011
    • Seedat Y, Rayner B. South African Hypertension Guideline 2011. S Afr Med 2012; 102:57-84.
    • (2012) S Afr Med , vol.102 , pp. 57-84
    • Seedat, Y.1    Rayner, B.2
  • 30
    • 79955827214 scopus 로고    scopus 로고
    • ACCF/AHA 2011 expert consensus document on hypertension in the elderly
    • American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents, American Academy of Neurology, American Geriatrics Society, American Society for Preventive Cardiology, American Society of Hypertension, American Society of Nephrology, Association of Black Cardiologists, European Society of Hypertension
    • American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents, American Academy of Neurology, American Geriatrics Society, American Society for Preventive Cardiology, American Society of Hypertension, American Society of Nephrology, Association of Black Cardiologists, European Society of Hypertension. ACCF/AHA 2011 expert consensus document on hypertension in the elderly. J Am Coll Cardiol 2011; 57:2037-2114.
    • (2011) J Am Coll Cardiol , vol.57 , pp. 2037-2114
  • 31
    • 78651250474 scopus 로고    scopus 로고
    • Hypertension Clinical management of primary hypertension in adults, UK. [Accessed 20 June 2014]
    • Hypertension Clinical management of primary hypertension in adults. National Institute of Health and Clinical Excellence. UK. http:// www.nice.org.uk/nicemedia/live/13561/56008.pdf. [Accessed 20 June 2014]
    • National Institute of Health and Clinical Excellence
  • 33
    • 74949089743 scopus 로고    scopus 로고
    • Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia
    • McGuinness B, Todd S, Passmore P, Bullock R. Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia. Cochrane Database Syst Rev 2009;CD004034.
    • (2009) Cochrane Database Syst Rev , pp. CD004034
    • McGuinness, B.1    Todd, S.2    Passmore, P.3    Bullock, R.4
  • 36
    • 84859001212 scopus 로고    scopus 로고
    • The Cochrane Collaboration's tool for assessing risk of bias in randomised trials
    • Cochrane bias methods group. Cochrane statistical methods group
    • Higgins J, Altman D, Gøtzsche P, Jüni P, Moher D, Oxman A, et al. Cochrane Bias Methods Group, Cochrane Statistical Methods Group. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ 2011; 343:d5928.
    • (2011) BMJ , vol.343 , pp. d5928
    • Higgins, J.1    Altman, D.2    Gøtzsche, P.3    Jüni, P.4    Moher, D.5    Oxman, A.6
  • 38
    • 10044293958 scopus 로고    scopus 로고
    • Calcium channel blockers and risk of AD: The Baltimore Longitudinal Study of Aging
    • Yasar S, Corrada M, Brookmeyer R, Kawas C. Calcium channel blockers and risk of AD: the Baltimore Longitudinal Study of Aging. Neurobiol Aging 2005; 26:157-163.
    • (2005) Neurobiol Aging , vol.26 , pp. 157-163
    • Yasar, S.1    Corrada, M.2    Brookmeyer, R.3    Kawas, C.4
  • 39
    • 66149154667 scopus 로고    scopus 로고
    • Duration of antihypertensive drug us and risk of dementia
    • Haag M, Hofman A, Koudstaal P, Breteler M, Stricker B. Duration of antihypertensive drug us and risk of dementia. Neurol 2009; 72:1727-1734.
    • (2009) Neurol , vol.72 , pp. 1727-1734
    • Haag, M.1    Hofman, A.2    Koudstaal, P.3    Breteler, M.4    Stricker, B.5
  • 40
    • 0037078284 scopus 로고    scopus 로고
    • Preservation of cognitive function with antihypertensive medications
    • Murray M, Lane K, Gao S, Evans R, Unverzagt F, Hall K, et al. Preservation of cognitive function with antihypertensive medications. Arch Int Med 2002; 162:2090-2096.
    • (2002) Arch Int Med , vol.162 , pp. 2090-2096
    • Murray, M.1    Lane, K.2    Gao, S.3    Evans, R.4    Unverzagt, F.5    Hall, K.6
  • 41
    • 84884628143 scopus 로고    scopus 로고
    • Antihypertensive drugs decrease risk of Alzheimer's disease: Ginkgo Evaluation on Memory Study
    • Yasar S, Xia J, Yao W, Furberg C, Xue Q, Mercado C, et al. Antihypertensive drugs decrease risk of Alzheimer's disease: Ginkgo Evaluation on Memory Study. Neurol 2013; 81:896-903.
    • (2013) Neurol , vol.81 , pp. 896-903
    • Yasar, S.1    Xia, J.2    Yao, W.3    Furberg, C.4    Xue, Q.5    Mercado, C.6
  • 42
    • 84884663826 scopus 로고    scopus 로고
    • Antihypertensive medication use and risk of cognitive impairment. The honolulu-asia aging study
    • Gelber R, Ross G, Petrovitch H, Masaki K, Launer L, White L. Antihypertensive medication use and risk of cognitive impairment. The Honolulu-Asia Aging Study. Neurol 2013; 81:1-8.
    • (2013) Neurol , vol.81 , pp. 1-8
    • Gelber, R.1    Ross, G.2    Petrovitch, H.3    Masaki, K.4    Launer, L.5    White, L.6
  • 43
    • 0033959061 scopus 로고    scopus 로고
    • On behalf of the NICS-EH study Group. Effect of long-term treatment with antihypertensive drugs on quality of life of elderly patients with hypertension: A double-blind comparative study between a calcium antagonist and a diuretic
    • Ogihara T, Kuramoto K. On behalf of the NICS-EH Study Group. Effect of long-term treatment with antihypertensive drugs on quality of life of elderly patients with hypertension: a double-blind comparative study between a calcium antagonist and a diuretic. Hypertens Res 2000; 23:33-37.
    • (2000) Hypertens Res , vol.23 , pp. 33-37
    • Ogihara, T.1    Kuramoto, K.2
  • 44
    • 20444427156 scopus 로고    scopus 로고
    • Morbidity and mortality after stroke, eprosartin compared with nitrendipine for secondary prevention: Principal results of a prospective randomised controlled study
    • Schrader J, Lüders S, Kulschewski A, Hammersen F, Plate K, Berger J, et al. Morbidity and mortality after stroke, eprosartin compared with nitrendipine for secondary prevention: principal results of a prospective randomised controlled study. Stroke 2005; 36:1218-1224.
    • (2005) Stroke , vol.36 , pp. 1218-1224
    • Schrader, J.1    Lüders, S.2    Kulschewski, A.3    Hammersen, F.4    Plate, K.5    Berger, J.6
  • 45
    • 14644411053 scopus 로고    scopus 로고
    • Crosssectional and longitudinal association between antihypertensive medications and cognitive impairment in an elderly population
    • Hajar I, Catoe H, Sixta S, Boland R, Johnson D, Hirth V, et al. Crosssectional and longitudinal association between antihypertensive medications and cognitive impairment in an elderly population. J Gerontol Med Sci 2005; 60A:67-73.
    • (2005) J Gerontol Med Sci , vol.60 A , pp. 67-73
    • Hajar, I.1    Catoe, H.2    Sixta, S.3    Boland, R.4    Johnson, D.5    Hirth, V.6
  • 46
    • 84877578318 scopus 로고    scopus 로고
    • Combination of antihypertensive therapy in the elderly, multicenter investigation (CAMUI) trial: Results after 1 year
    • Sato N, Saijo Y, Sasagawa Y, Morimoto H, Takeuchi T, Sano H, et al. Combination of antihypertensive therapy in the elderly, multicenter investigation (CAMUI) trial: results after 1 year. J Hypertens 2013; 31:1245-1255.
    • (2013) J Hypertens , vol.31 , pp. 1245-1255
    • Sato, N.1    Saijo, Y.2    Sasagawa, Y.3    Morimoto, H.4    Takeuchi, T.5    Sano, H.6
  • 47
    • 79956329625 scopus 로고    scopus 로고
    • Use of calcium channel blockers is associated with better cognitive performance in older hypertensive patients with subjective memory complaints
    • Watfa G, Rossignol P, Kearney-Schwartz A, Renaud F, Bracard S, Felblinger J, et al. Use of calcium channel blockers is associated with better cognitive performance in older hypertensive patients with subjective memory complaints. J Hypertens 2010; 28:2485-2493.
    • (2010) J Hypertens , vol.28 , pp. 2485-2493
    • Watfa, G.1    Rossignol, P.2    Kearney-Schwartz, A.3    Renaud, F.4    Bracard, S.5    Felblinger, J.6
  • 48
    • 68949085051 scopus 로고    scopus 로고
    • Antihypertensive agents and risk of Parkinson's disease, essential tremor and dementia: A population-based prospective study (NEDICES)
    • On behalf of the neurological disorders in central Spain (NEDICES) study group.
    • Louis E, Benito-León J, Bermejo-Pareja F. on behalf of the Neurological Disorders in Central Spain (NEDICES) study group. Antihypertensive agents and risk of Parkinson's disease, essential tremor and dementia: a population-based prospective study (NEDICES). Neuroepidemiology 2009; 33:286-292.
    • (2009) Neuroepidemiology , vol.33 , pp. 286-292
    • Louis, E.1    Benito-León, J.2    Bermejo-Pareja, F.3
  • 49
    • 0038669268 scopus 로고    scopus 로고
    • Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease
    • The PROGRESS Collaborative Group
    • The PROGRESS Collaborative Group. Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease. Arch Intern Med 2003; 163:1069-1075.
    • (2003) Arch Intern Med , vol.163 , pp. 1069-1075
  • 50
    • 0036046464 scopus 로고    scopus 로고
    • Nimodipine for primary degenerative, mixed and vascular dementia
    • Birks J, López-Arrieta J. Nimodipine for primary degenerative, mixed and vascular dementia. Cochrane Database Syst Rev 2002;CD000147.
    • (2002) Cochrane Database Syst Rev , pp. CD000147
    • Birks, J.1    López-Arrieta, J.2
  • 51
    • 79952860789 scopus 로고    scopus 로고
    • Selective antihypertensive dihydropyridines lower Aß accumulation by targeting both the production and the clearance of Aß across the bloodbrain barrier
    • Paris D, Bachmeier C, Patel N, Quadros A, Volmar C, Laporte V, et al. Selective antihypertensive dihydropyridines lower Aß accumulation by targeting both the production and the clearance of Aß across the bloodbrain barrier. Mol Med 2011; 17:149-162.
    • (2011) Mol Med , vol.17 , pp. 149-162
    • Paris, D.1    Bachmeier, C.2    Patel, N.3    Quadros, A.4    Volmar, C.5    Laporte, V.6
  • 52
    • 84879349584 scopus 로고    scopus 로고
    • Calcium channel blockers and dementia
    • Nimmrich V, Eckert A. Calcium channel blockers and dementia. Br J Pharmacol 2013; 169:1203-1210.
    • (2013) Br J Pharmacol , vol.169 , pp. 1203-1210
    • Nimmrich, V.1    Eckert, A.2
  • 53
  • 54
    • 0033847175 scopus 로고    scopus 로고
    • Sipatrigine (BW 619C89) is a neuroprotective agent and a sodium channel and calcium channel inhibitor
    • Hainsworth A, Stefani A, Calabresi P, Smith T, Leach M. Sipatrigine (BW 619C89) is a neuroprotective agent and a sodium channel and calcium channel inhibitor. CNS Drug Rev 2000; 6:111-134.
    • (2000) CNS Drug Rev , vol.6 , pp. 111-134
    • Hainsworth, A.1    Stefani, A.2    Calabresi, P.3    Smith, T.4    Leach, M.5
  • 55
    • 17144400513 scopus 로고    scopus 로고
    • Gabapentin-mediated effects on voltage-and ligand-gated currents
    • Stefani A, Hainsworth A. Gabapentin-mediated effects on voltage-and ligand-gated currents. Curr Neuropharmacol 2003; 1:237-244.
    • (2003) Curr Neuropharmacol , vol.1 , pp. 237-244
    • Stefani, A.1    Hainsworth, A.2


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