-
2
-
-
33744730025
-
Personalized medicine and development of targeted therapies: The upcoming challenge for diagnostic molecular pathology. A review
-
Dietel M, Sers C. Personalized medicine and development of targeted therapies: the upcoming challenge for diagnostic molecular pathology. A review. Virchows Arch 2006;448:744-755.
-
(2006)
Virchows Arch
, vol.448
, pp. 744-755
-
-
Dietel, M.1
Sers, C.2
-
3
-
-
77954827460
-
The path to personalized medicine
-
Hamburg MA, Collins FS. The path to personalized medicine. N Engl J Med 2010;363:301-304.
-
(2010)
N Engl J Med
, vol.363
, pp. 301-304
-
-
Hamburg, M.A.1
Collins, F.S.2
-
4
-
-
34547638047
-
Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
-
Soda M, Choi YL, Enomoto M, et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 2007;448:561-566.
-
(2007)
Nature
, vol.448
, pp. 561-566
-
-
Soda, M.1
Choi, Y.L.2
Enomoto, M.3
-
5
-
-
70349336416
-
Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK
-
Shaw AT, Yeap BY, Mino-Kenudson M, et al. Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK. J Clin Oncol 2009;27:4247-4253.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4247-4253
-
-
Shaw, A.T.1
Yeap, B.Y.2
Mino-Kenudson, M.3
-
6
-
-
80053386829
-
Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: A retrospective analysis
-
Shaw AT, Yeap BY, Solomon BJ, et al. Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis. Lancet Oncol 2011;12:1004-1012.
-
(2011)
Lancet Oncol
, vol.12
, pp. 1004-1012
-
-
Shaw, A.T.1
Yeap, B.Y.2
Solomon, B.J.3
-
7
-
-
79960218807
-
Genotype-driven therapies for non-small cell lung cancer: Focus on EGFR, KRAS and ALK gene abnormalities
-
Gaughan EM, Costa DB. Genotype-driven therapies for non-small cell lung cancer: focus on EGFR, KRAS and ALK gene abnormalities. Ther Adv Med Oncol 2011;3:113-125.
-
(2011)
Ther Adv Med Oncol
, vol.3
, pp. 113-125
-
-
Gaughan, E.M.1
Costa, D.B.2
-
8
-
-
78651339071
-
EGFR mutation detection in NSCLC-assessment of diagnostic application and recommendations of the German Panel for Mutation Testing in NSCLC
-
Penzel R, Sers C, Chen Y, et al. EGFR mutation detection in NSCLC-assessment of diagnostic application and recommendations of the German Panel for Mutation Testing in NSCLC. Virchows Arch 2011;458:95-98.
-
(2011)
Virchows Arch
, vol.458
, pp. 95-98
-
-
Penzel, R.1
Sers, C.2
Chen, Y.3
-
9
-
-
77958185649
-
Consensus for EGFR mutation testing in non-small cell lung cancer: Results from a European workshop
-
Pirker R, Herth FJ, Kerr KM, et al. Consensus for EGFR mutation testing in non-small cell lung cancer: results from a European workshop: J Thorac Oncol 2010;5:1706-1713.
-
(2010)
J Thorac Oncol
, vol.5
, pp. 1706-1713
-
-
Pirker, R.1
Herth, F.J.2
Kerr, K.M.3
-
10
-
-
84867395679
-
Consensus statement on testing for EML4-ALK in non-small-cell carcinomas of the lung
-
Thunnissen E, Bubendorf L, Dietel M, et al. Consensus statement on testing for EML4-ALK in non-small-cell carcinomas of the lung. Virch Arch 2012;461:245-257.
-
(2012)
Virch Arch
, vol.461
, pp. 245-257
-
-
Thunnissen, E.1
Bubendorf, L.2
Dietel, M.3
-
11
-
-
84879888405
-
Anaplastic lymphoma kinase (ALK) gene rearrangement in non-small cell lung cancer (NSCLC): Results of a multi-centre ALK-testing
-
V Laffert M, Warth A, Penzel R, et al. Anaplastic lymphoma kinase (ALK) gene rearrangement in non-small cell lung cancer (NSCLC): results of a multi-centre ALK-testing. Lung Cancer 2013;81:200-206.
-
(2013)
Lung Cancer
, vol.81
, pp. 200-206
-
-
V Laffert, M.1
Warth, A.2
Penzel, R.3
-
12
-
-
78349237453
-
Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment
-
Camidge DR, Kono SA, Flacco A, et al. Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment. Clin Cancer Res 2010;16:5581-5590.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 5581-5590
-
-
Camidge, D.R.1
Kono, S.A.2
Flacco, A.3
-
13
-
-
84860500563
-
Clinicopathologic implication of ALK rearrangement in surgically resected lung cancer: A proposal of diagnostic algorithm for ALK-rearranged adenocarcinoma
-
Paik JH, Choi CM, Kim H, et al. Clinicopathologic implication of ALK rearrangement in surgically resected lung cancer: a proposal of diagnostic algorithm for ALK-rearranged adenocarcinoma. Lung Cancer 2012;76:403-409.
-
(2012)
Lung Cancer
, vol.76
, pp. 403-409
-
-
Paik, J.H.1
Choi, C.M.2
Kim, H.3
-
14
-
-
80051784751
-
Detection of ALK gene rearrangement in non-small cell lung cancer: A comparison of fluorescence in situ hybridization and chromogenic in situ hybridization with correlation of ALK protein expression
-
Kim H, Yoo SB, Choe JY, et al. Detection of ALK gene rearrangement in non-small cell lung cancer: a comparison of fluorescence in situ hybridization and chromogenic in situ hybridization with correlation of ALK protein expression. J Thorac Oncol 2011;6:1359-1366.
-
(2011)
J Thorac Oncol
, vol.6
, pp. 1359-1366
-
-
Kim, H.1
Yoo, S.B.2
Choe, J.Y.3
-
15
-
-
85028169371
-
-
Detection of Anaplastic Lymphoma Kinase (ALK) gene rearrangement in Non-Small Cell Lung Cancer (NSCLC): A glance at "borderline" cases Poster was presented at the Poster-ID: 1195P
-
von Laffert M, Berg E, Lenze D, et al. Detection of Anaplastic Lymphoma Kinase (ALK) gene rearrangement in Non-Small Cell Lung Cancer (NSCLC): a glance at "borderline" cases. Poster was presented at the ECCO/ESMO 2012 in Vienna, Poster-ID: 1195P.
-
ECCO/ESMO 2012 in Vienna
-
-
Von Laffert, M.1
Berg, E.2
Lenze, D.3
-
16
-
-
80053043565
-
Bright-field dual-color chromogenic in situ hybridization for diagnosing echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase-positive lung adenocarcinomas
-
Yoshida A, Tsuta K, Nitta H, et al. Bright-field dual-color chromogenic in situ hybridization for diagnosing echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase-positive lung adenocarcinomas. J Thorac Oncol 2011;6:1677-1686.
-
(2011)
J Thorac Oncol
, vol.6
, pp. 1677-1686
-
-
Yoshida, A.1
Tsuta, K.2
Nitta, H.3
-
17
-
-
84857781304
-
Dual IHC and FISH testing for ALK gene rearrangement in lung adenocarcinomas in a routine practice: A French study
-
McLeer-Florin A, Moro-Sibilot D, Melis A, et al. Dual IHC and FISH testing for ALK gene rearrangement in lung adenocarcinomas in a routine practice: a French study. J Thorac Oncol 2012;7:348-354.
-
(2012)
J Thorac Oncol
, vol.7
, pp. 348-354
-
-
McLeer-Florin, A.1
Moro-Sibilot, D.2
Melis, A.3
-
18
-
-
65249095599
-
The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS
-
Wong DW, Leung EL, So KK, et al. The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS. Cancer 2009;115:1723-1733.
-
(2009)
Cancer
, vol.115
, pp. 1723-1733
-
-
Wong, D.W.1
Leung, E.L.2
So, K.K.3
-
19
-
-
77953291664
-
The biology and treatment of EML4-ALK non-small cell lung cancer
-
Sasaki T, Rodig SJ, Chirieac LR, et al. The biology and treatment of EML4-ALK non-small cell lung cancer. Eur J Cancer 2010;46:1773-1780.
-
(2010)
Eur J Cancer
, vol.46
, pp. 1773-1780
-
-
Sasaki, T.1
Rodig, S.J.2
Chirieac, L.R.3
-
20
-
-
79951774364
-
Correlation of IHC and FISH for ALK gene rearrangement in non-small cell lung carcinoma: IHC score algorithm for FISH
-
Yi ES, Boland JM, Maleszewski JJ, et al. Correlation of IHC and FISH for ALK gene rearrangement in non-small cell lung carcinoma: IHC score algorithm for FISH. J Thorac Oncol 2011;6:459-465.
-
(2011)
J Thorac Oncol
, vol.6
, pp. 459-465
-
-
Yi, E.S.1
Boland, J.M.2
Maleszewski, J.J.3
-
21
-
-
84870703622
-
Role of fluorescence in situ hybridization in lung cancer cytology
-
Savic S, Bubendorf L. Role of fluorescence in situ hybridization in lung cancer cytology. Acta Cytol 2012;56:611-621.
-
(2012)
Acta Cytol
, vol.56
, pp. 611-621
-
-
Savic, S.1
Bubendorf, L.2
-
22
-
-
84864439345
-
Why technical aspects rather than biology explain cellular heterogeneity in ALK-positive non-small cell lung cancer
-
McLeer-Florin A, Lantuéjoul S. Why technical aspects rather than biology explain cellular heterogeneity in ALK-positive non-small cell lung cancer. J Thorac Dis 2012;4:240-241.
-
(2012)
J Thorac Dis
, vol.4
, pp. 240-241
-
-
McLeer-Florin, A.1
Lantuéjoul, S.2
-
23
-
-
84887075100
-
Chromogenic in situ hybridization is a reliable assay for detection of ALK rearrangements in adenocarcinomas of the lung
-
Schildhaus HU, Deml KF, Schmitz K, et al. Chromogenic in situ hybridization is a reliable assay for detection of ALK rearrangements in adenocarcinomas of the lung. Mod Pathol 2013;26:1468-1477.
-
(2013)
Mod Pathol
, vol.26
, pp. 1468-1477
-
-
Schildhaus, H.U.1
Deml, K.F.2
Schmitz, K.3
-
24
-
-
84880921897
-
Round robin test for detection of genomic aberrations in non-Hodgkin lymphoma by in situ hybridization
-
Barth TF, Floßbach L, Bernd HW, et al. [Round robin test for detection of genomic aberrations in non-Hodgkin lymphoma by in situ hybridization]. Pathologe 2013;34:329-334.
-
(2013)
Pathologe
, vol.34
, pp. 329-334
-
-
Barth, T.F.1
Floßbach, L.2
Bernd, H.W.3
-
25
-
-
84864432794
-
Correlations between the percentage of tumor cells showing an anaplastic lymphoma kinase (ALK) gene rearrangement, ALK signal copy number, and response to crizotinib therapy in ALK fluorescence in situ hybridization-positive nonsmall cell lung cancer
-
Camidge DR, Theodoro M, Maxson DA, et al. Correlations between the percentage of tumor cells showing an anaplastic lymphoma kinase (ALK) gene rearrangement, ALK signal copy number, and response to crizotinib therapy in ALK fluorescence in situ hybridization-positive nonsmall cell lung cancer. Cancer 2012;118:4486-4494.
-
(2012)
Cancer
, vol.118
, pp. 4486-4494
-
-
Camidge, D.R.1
Theodoro, M.2
Maxson, D.A.3
-
26
-
-
79951761225
-
Finding ALK-positive lung cancer: What are we really looking for?
-
Camidge DR, Hirsch FR, Varella-Garcia M, et al. Finding ALK-positive lung cancer: what are we really looking for? J Thorac Oncol 2011;6:411-413.
-
(2011)
J Thorac Oncol
, vol.6
, pp. 411-413
-
-
Camidge, D.R.1
Hirsch, F.R.2
Varella-Garcia, M.3
-
27
-
-
79952011545
-
Is FISH floating or still swimming in the lung cancer ocean?
-
Cappuzzo F, Camidge DR, Varella-Garcia M. Is FISH floating or still swimming in the lung cancer ocean? Ann Oncol 2011;22:493-499.
-
(2011)
Ann Oncol
, vol.22
, pp. 493-499
-
-
Cappuzzo, F.1
Camidge, D.R.2
Varella-Garcia, M.3
-
28
-
-
34247894060
-
Guidance for fluorescence in situ hybridization testing in hematologic disorders
-
Wolff DJ, Bagg A, Cooley LD, et al.; Association for Molecular Pathology Clinical Practice Committee; American College of Medical Genetics Laboratory Quality Assurance Committee. Guidance for fluorescence in situ hybridization testing in hematologic disorders. J Mol Diagn 2007;9:134-143.
-
(2007)
J Mol Diagn
, vol.9
, pp. 134-143
-
-
Wolff, D.J.1
Bagg, A.2
Cooley, L.D.3
-
29
-
-
36248968768
-
Interphase FISH as a new tool in tumor pathology
-
Tibiletti MG. Interphase FISH as a new tool in tumor pathology. Cytogenet Genome Res 2007;118:229-236.
-
(2007)
Cytogenet Genome Res
, vol.118
, pp. 229-236
-
-
Tibiletti, M.G.1
-
30
-
-
34047170655
-
Fluorescent in situ hybridization on tissue microarrays: Challenges and solutions
-
Brown LA, Huntsman D. Fluorescent in situ hybridization on tissue microarrays: challenges and solutions. J Mol Histol 2007;38:151-157.
-
(2007)
J Mol Histol
, vol.38
, pp. 151-157
-
-
Brown, L.A.1
Huntsman, D.2
-
31
-
-
63949086127
-
KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer
-
Takeuchi K, Choi YL, Togashi Y, et al. KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer. Clin Cancer Res 2009;15:3143-3149.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3143-3149
-
-
Takeuchi, K.1
Choi, Y.L.2
Togashi, Y.3
-
32
-
-
77649091118
-
A novel, highly sensitive antibody allows for the routine detection of ALK-rearranged lung adenocarcinomas by standard immunohistochemistry
-
Mino-Kenudson M, Chirieac LR, Law K, et al. A novel, highly sensitive antibody allows for the routine detection of ALK-rearranged lung adenocarcinomas by standard immunohistochemistry. Clin Cancer Res 2010;16:1561-1571.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1561-1571
-
-
Mino-Kenudson, M.1
Chirieac, L.R.2
Law, K.3
-
33
-
-
84874023763
-
Combined use of ALK immunohistochemistry and FISH for optimal detection of ALK-rearranged lung adenocarcinomas
-
Sholl LM, Weremowicz S, Gray SW, et al. Combined use of ALK immunohistochemistry and FISH for optimal detection of ALK-rearranged lung adenocarcinomas. J Thorac Oncol 2013;8:322-328.
-
(2013)
J Thorac Oncol
, vol.8
, pp. 322-328
-
-
Sholl, L.M.1
Weremowicz, S.2
Gray, S.W.3
-
34
-
-
85028170131
-
External quality assessment for ALK immunohistochemistry testing in lung adenocarcinoma within the European Thoracic Oncology Platform Lungscape project
-
Presented at ESMO
-
Thunnissen E, Kerr KM, Bubendorf L, et al. External quality assessment for ALK immunohistochemistry testing in lung adenocarcinoma within the European Thoracic Oncology Platform Lungscape project. Ann Oncol 23(Suppl 9):ix80. Presented at ESMO 2012; Abstract 193P.
-
(2012)
Ann Oncol
, vol.23
, pp. ix80
-
-
Thunnissen, E.1
Kerr, K.M.2
Bubendorf, L.3
-
35
-
-
84880917013
-
Detection of ALK rearrangement by immunohistochemistry in lung adenocarcinoma and the identification of a novel EML4-ALK variant
-
To KF, Tong JH, Yeung KS, et al. Detection of ALK rearrangement by immunohistochemistry in lung adenocarcinoma and the identification of a novel EML4-ALK variant. J Thorac Oncol 2013;8:883-891.
-
(2013)
J Thorac Oncol
, vol.8
, pp. 883-891
-
-
To, K.F.1
Tong, J.H.2
Yeung, K.S.3
-
36
-
-
84880917028
-
Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: Guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology
-
Lindeman NI, Cagle PT, Beasley MB, et al. Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology. J Thorac Oncol 2013;8:823-859.
-
(2013)
J Thorac Oncol
, vol.8
, pp. 823-859
-
-
Lindeman, N.I.1
Cagle, P.T.2
Beasley, M.B.3
|