Hepatoprotective effect of fermented ginseng and its major constituent compound K in a rat model of paracetamol (acetaminophen)-induced liver injury

Journal of Pharmacy and Pharmacology

Volumn 67, Issue 4, 2015, Pages 565-572

  Igami, Kentaro ^a   Shimojo, Yosuke ^a   Ito, Hisatomi ^a   Miyazaki, Toshitsugu ^a   Kashiwada, Yoshiki ^b  

^a Nishi ku   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

acetaminophen; compound K; DNA microarray; fermented ginseng; JNK phosphorylation

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; FERMENTED GINSENG EXTRACT; FERMENTED RED GINSENG EXTRACT; GINSENG EXTRACT; GINSENOSIDE; GLUTATHIONE TRANSFERASE; PARACETAMOL; PROTOPANAXADIOL 20 O BETA DEXTRO GLUCOPYRANOSIDE; SILYMARIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; GINSENOSIDE M1; PLANT EXTRACT;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CHEMICAL COMPOSITION; CONTROLLED STUDY; DNA MICROARRAY; GENE EXPRESSION; HEPG2 CELL LINE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LIVER PROTECTION; MALE; NONHUMAN; PROTEIN PHOSPHORYLATION; RAT; SINGLE DRUG DOSE; TOXIC HEPATITIS; WESTERN BLOTTING; ANIMAL; BLOOD; DISEASE MODEL; DRUG EFFECTS; DRUG-INDUCED LIVER INJURY; ENZYMOLOGY; FERMENTATION; LIVER; METABOLISM; PANAX; PATHOLOGY; PHOSPHORYLATION; PHYTOTHERAPY; WISTAR RAT;

ACETAMINOPHEN; ANIMALS; ANTI-INFLAMMATORY AGENTS; DISEASE MODELS, ANIMAL; DRUG-INDUCED LIVER INJURY; FERMENTATION; GINSENOSIDES; HEP G2 CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER; MALE; PANAX; PHOSPHORYLATION; PHYTOTHERAPY; PLANT EXTRACTS; RATS, WISTAR;

EID: 84925802950     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/jphp.12342     Document Type: Article

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