Linking Genetics of Brain Changes to Alzheimer's Disease: Sparse Whole Genome Association Scan of Regional MRI Volumes in the ADNI and AddNeuroMed Cohorts

Journal of Alzheimer's Disease

Volumn 45, Issue 3, 2015, Pages 851-864

  Khondoker, Mizanur ^a,b   Newhouse, Stephen ^a,b   Westman, Eric ^a,d   Muehlboeck, J Sebastian ^a,d   Mecocci, Patrizia ^e   Vellas, Bruno ^f   Tsolaki, Magda ^f   Kłoszewska, Iwona ^g   Soininen, Hilkka ^h   Lovestone, Simon ⁱ   Dobson, Richard ^a,c   Simmons, Andrew ^a,c  

^a King's College London   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c Leicester NIHR Biomedical Research Unit in Cardiovascular Disease   (United Kingdom)

^d KAROLINSKA INSTITUTE   (Sweden)

^e UNIVERSITY OF PERUGIA   (Italy)

^f UNIVERSITÉ DE TOULOUSE   (France)

^g MEDICAL UNIVERSITY OF LODZ   (Poland)

^h KUOPIO UNIVERSITY HOSPITAL   (Finland)

ⁱ UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Alzheimer's disease; genome wide association study; imaging quantitative trait loci; magnetic resonance imaging; mild cognitive impairment

Indexed keywords

JUNCTIONAL ADHESION MOLECULE B; PROTEIN HOMER 2; CARRIER PROTEIN; CELL ADHESION MOLECULE; CELL CYCLE PROTEIN; EOMES PROTEIN, HUMAN; JAM2 PROTEIN, HUMAN; NUCLEAR PROTEIN; PROTEIN HOMER; PROTEIN TYROSINE KINASE; T BOX TRANSCRIPTION FACTOR; WEE1 PROTEIN, HUMAN;

AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; BRAIN REGION; CHROMOSOME 15; CHROMOSOME 19; CHROMOSOME NUMBER; CONTROLLED STUDY; DISEASE ASSOCIATION; ENTORHINAL CORTEX; EOMES GENE; FEMALE; GENE; GENETIC ASSOCIATION; GENETIC MARKER; GENETIC SUSCEPTIBILITY; HIPPOCAMPUS; HUMAN; MAJOR CLINICAL STUDY; MALE; MINI MENTAL STATE EXAMINATION; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; THALAMUS; WEE1 GENE; BRAIN; COHORT ANALYSIS; GENETICS; PATHOLOGY; SEX DIFFERENCE; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; BRAIN; CARRIER PROTEINS; CELL ADHESION MOLECULES; CELL CYCLE PROTEINS; COHORT STUDIES; FEMALE; GENETIC ASSOCIATION STUDIES; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NUCLEAR PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN-TYROSINE KINASES; QUANTITATIVE TRAIT LOCI; SEX FACTORS; T-BOX DOMAIN PROTEINS;

EID: 84925718534     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-142214     Document Type: Article

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