Parental psychopathology and treatment outcome for anxious youth: Roles of family functioning and caregiver strain

Journal of Consulting and Clinical Psychology

Volumn 83, Issue 1, 2015, Pages 213-224

  Schleider, Jessica L ^a   Ginsburg, Golda S ^b   Keeton, Courtney P ^b   Weisz, John R ^a   Birmaher, Boris ^c   Kendall, Phillip C ^d   Piacentini, John ^e   Sherrill, Joel ^f   Walkup, John T ^g  

^a HARVARD UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^d TEMPLE UNIVERSITY   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^g NEW YORK PRESBYTERIAN HOSPITAL   (United States)

Author keywords

Family functioning; Mediation; Parental psychopathology; Youth anxiety treatment

Indexed keywords

PLACEBO; SERTRALINE; ANTIDEPRESSANT AGENT;

ADOLESCENT; ANXIETY ASSESSMENT; ANXIETY DISORDER; ARTICLE; CAREGIVER BURDEN; CHILD; CLINICAL GLOBAL IMPRESSION SCALE; COGNITIVE THERAPY; CONTROLLED STUDY; DISEASE SEVERITY; FAMILIAL DISEASE; FAMILY FUNCTIONING; FEMALE; GENERALIZED ANXIETY DISORDER; HUMAN; MAJOR CLINICAL STUDY; MALE; PARENT; RANDOMIZED CONTROLLED TRIAL; SELF REPORT; SEPARATION ANXIETY; SOCIAL PHOBIA; TREATMENT DURATION; TREATMENT OUTCOME; TREATMENT RESPONSE; ANIMAL; ANXIETY DISORDERS; CAREGIVER; CHILD OF IMPAIRED PARENTS; COMPLICATION; FAMILY; MENTAL DISEASE; MENTAL STRESS; PROCEDURES; PSYCHOLOGY; STATISTICS AND NUMERICAL DATA;

ADOLESCENT; ANIMALS; ANTIDEPRESSIVE AGENTS; ANXIETY DISORDERS; CAREGIVERS; CHILD; CHILD OF IMPAIRED PARENTS; COGNITIVE THERAPY; FAMILY; FEMALE; HUMANS; MALE; MENTAL DISORDERS; PARENTS; SELF REPORT; SERTRALINE; STRESS, PSYCHOLOGICAL; TREATMENT OUTCOME;

EID: 84925702744     PISSN: 0022006X     EISSN: 19392117     Source Type: Journal    
DOI: 10.1037/a0037935     Document Type: Article

References (74)

1. American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed., text rev.). Washington, DC: Author.
2. Angold, A., Messer, S. C., Stangl, D., Farmer, E. M., Costello, E. J., & Burns, B. J. (1998). Perceived parental burden and service use for child and adolescent psychiatric disorders. American Journal of Public Health, 88, 75-80. doi:10.2105/AJPH.88.1.75
3. Barrett, P. M., Fox, T., & Farrell, L. J. (2005). Parent- child interactions with anxious children and with their siblings: An observational study. Behaviour Change, 22, 220-235. doi:10.1375/bech.22.4.220
4. Berman, S. L., Weems, C. F., Silverman, W. K., & Kurtines, W. M. (2000). Predictors of outcome in exposure-based and cognitive and behavioral treatments for phobic and anxiety disorders in children. Behavior Therapy, 31, 713-731. doi:10.1016/S0005-7894(00)80040-4
5. Birmaher, B., Axelson, D. A., Monk, K., Kalas, C., Clark, D. B., Ehmann, M., . . . Brent, D. A. (2003). Fluoxetine for the treatment of childhood anxiety disorders. Journal of the American Academy of Child & Adolescent Psychiatry, 42, 415- 423. doi:10.1097/01.CHI.0000037049.04952.9F
6. Birmaher, B., Brent, D., Chiappetta, L., Bridge, J., Monga, S., & Baugher, M. (1999). Psychometric properties of the Screen for Child Anxiety Related Emotional Disorders (SCARED): A replication study. Journal of the American Academy of Child & Adolescent Psychiatry, 38, 1230-1236. doi:10.1097/00004583-199910000-00011
7. Birmaher, B., Khetarpal, S., Brent, D., Cully, M., Balach, L., Kaufman, J., & Neer, S. M. (1997). The Screen for Child Anxiety Related Emotional Disorders (SCARED): Scale construction and psychometric characteristics. Journal of the American Academy of Child & Adolescent Psychiatry, 36, 545-553. doi:10.1097/00004583-199704000-00018
8. Bloomquist, M. L., & Harris, W. G. (1984). Measuring family functioning with the MMPI: A reliability and concurrent validity study of three MMPI scales. Journal of Clinical Psychology, 40, 1209-1214. doi: 10.1002/1097-4679(198409)40:5-1209::AID-JCLP2270400515-3.0.CO;2-S
9. Boulet, J., & Boss, M. W. (1991). Reliability and validity of the Brief Symptom Inventory. Psychological Assessment, 3, 433- 437. doi: 10.1037/1040-3590.3.3.433
10. Clausen, J. A., & Yarrow, M. R. (1955). Mental illness and the family. Journal of Social Issues, 11, 3-5. doi:10.1111/j.1540-4560.1955.tb00338.x
11. Cobham, V. E., Dadds, M. R., & Spence, S. H. (1998). The role of parental anxiety in the treatment of childhood anxiety. Journal of Consulting and Clinical Psychology, 66, 893-905. doi:10.1037/0022-006X.66.6.893
12. Compton, S. N., March, J. S., Brent, D., Albano, A., Weersing, V. R., & Curry, J. (2004). Cognitive-behavioral psychotherapy for anxiety and depressive disorders in children and adolescents: An evidence-based medicine review. Journal of the American Academy of Child & Adolescent Psychiatry, 43, 930-959. doi:10.1097/01.chi.0000127589.57468.bf
13. Compton, S. N., Peris, T. S., Almirall, D., Birmaher, B., Sherrill, J., Kendall, P. C., . . . Albano, A. M. (2014). Predictors and moderators of treatment response in childhood anxiety disorders: Results from the CAMS trial. Journal of Consulting and Clinical Psychology, 82, 212-224. doi:10.1037/a0035458
14. Compton, S. N., Walkup, J. T., Albano, A. M., Piacentini, J. C., Birmaher, B., Sherrill, J. T., . . . March, J. S. (2010). Child/Adolescent Anxiety Multimodal Study (CAMS): Rationale, design, and methods. Child and Adolescent Psychiatry and Mental Health, 4, 1-8. doi:10.1186/1753-2000-4-1
15. Costello, E. J., Egger, H., & Angold, A. (2005). 10-year research update review: The epidemiology of child and adolescent psychiatric disorders: I. Methods and public health burden. Journal of the American Academy of Child & Adolescent Psychiatry, 44, 972-986. doi:10.1097/01.chi.0000172552.41596.6f
16. Crawford, A. M., & Manassis, K. (2001). Familial predictors of treatment outcome in childhood anxiety disorders. Journal of the American Academy of Child & Adolescent Psychiatry, 40, 1182-1189. doi:10.1097/00004583-200110000-00012
17. Cummings, E. M., Keller, P. S., & Davies, P. T. (2005). Towards a family process model of maternal and paternal depressive symptoms: Exploring multiple relations with child and family functioning. Journal of Child Psychology and Psychiatry, 46, 479-489. doi:10.1111/j.1469-7610.2004.00368.x
18. Dawson, D. (1991). Family structure and children's health and well-being: Data from the 1988 National Health Interview Survey on Child Health. Journal of Marriage and the Family, 53, 573-584. doi:10.2307/352734
19. Derogatis, L. R. (1977). The SCL-90-R Manual I: Scoring, administration and procedures for the SCL-90. Baltimore, MD: Clinical Psychometric Research.
20. Derogatis, L. R. (1993). The Brief Symptom Inventory (BSI): Administration, scoring, and procedure manual (4th ed.). Minneapolis, MN: National Computer Systems.
21. Derogatis, L. R., & Melisaratos, N. (1983). The Brief Symptom Inventory: An introductory report. Psychological Medicine, 13, 595-605. doi: 10.1017/S0033291700048017
22. Fisher, G., Benson, P., & Tessler, R. (1990). Family response to mental illness: Developments since deinstitutionalization. In J. R. Greenley (Ed.), Research in community and mental health (Vol. 6, pp. 203-236). Greenwich, CT: JAI Press.
23. Ginsburg, G. S., Keeton, C. P., Drazdowski, T. K., & Riddle, M. A. (2011). The utility of clinicians ratings of anxiety using the Pediatric Anxiety Rating Scale (PARS). Child & Youth Care Forum, 40, 93-105. doi: 10.1007/s10566-010-9125-3
24. Ginsburg, G. S., Kendall, P. C., Sakolsky, D., Compton, S. N., Piacentini, J., Albano, A. M., . . . March, J. (2011). Remission after acute treatment in children and adolescents with anxiety disorders: Findings from the CAMS. Journal of Consulting and Clinical Psychology, 79, 806-813. doi:10.1037/a0025933
25. Ginsburg, G. S., Siqueland, L., Masia-Warner, C., & Hedtke, K. A. (2004). Anxiety disorders in children: Family matters. Cognitive and Behavioral Practice, 11, 408-412. doi:10.1016/S1077-7229(04)80005-1
26. Grad, J., & Sainsbury, P. (1968). The effects that patients have on their family in a community care and control psychiatric service: A two-year follow-up. British Journal of Psychiatry, 114, 265-278. doi:10.1192/bjp.114.508.265
27. Guy, W. (1976). The Clinical Global Impressions. In W. Guy (Ed.), ECDEU assessment manual for psychopharmacology-Revised (pp. 218-222). Rockville, MD: National Institute of Mental Health.
28. Hollingshead, A. B. (1971). Commentary on "The indiscriminate state of social class measurement." Social Forces, 49, 563-567. doi:10.1093/sf/49.4.563
29. Hughes, A. A., Hedtke, K. A., & Kendall, P. C. (2008). Family functioning in families of children with anxiety disorders. Journal of Family Psychology, 22, 325-328. doi:10.1037/0893-3200.22.2.325
30. Jackson, A. P., & Huang, C. C. (2000). Parenting stress and behavior among single mothers of preschoolers: The mediating role of selfefficacy. Journal of Social Service Research, 26, 29-42. doi:10.1300/J079v26n04-02
31. Jacob, T. (1995). The role of the time frame in the assessment of family functioning. Journal of Marital and Family Therapy, 21, 281-288. doi:10.1111/j.1752-0606.1995.tb00162.x
32. Keeton, C. P., Ginsburg, G. S., Drake, K. L., Sakolsky, D., Kendall, P. C., Birmaher, B., Albano, A. M., . . . Walkup, J. T. (2013). Benefits of child-focused anxiety treatments for parents and family functioning. Depression and Anxiety, 8, 865-872. doi:10.1002/da.22055
33. Kendall, P. C. (1994). Treating anxiety disorders in children: Results of a randomized clinical trial. Journal of Consulting and Clinical Psychology, 62, 200-210. doi:10.1037/0022-006X.62.1.100
34. Kendall, P. C., Choudhury, M., Hudson, J., & Webb, A. (2002). "The C.A.T. Project" manual for the cognitive-behavioral treatment of anxious adolescents. Ardmore, PA: Workbook.
35. Kendall, P. C., Compton, S. N., Walkup, J. T., Birmaher, B., Albano, A. M., Sherrill, J., . . . Piacentini, J. (2010). Clinical characteristics of anxiety disordered youth. Journal of Anxiety Disorders, 24, 360-365. doi:10.1016/j.janxdis.2010.01.009
36. Kendall, P. C., & Hedtke, K. A. (2006). Cognitive-behavioral therapy for anxious children: Therapist manual (3rd ed.). Ardmore, PA: Workbook.
37. Khanna, M. S., & Kendall, P. C. (2009). Exploring the role of parent training in the cognitive behavioral treatment of anxiety disorders in youth. Journal of Consulting and Clinical Psychology, 77, 981-986. doi:10.1037/a0016920
38. Kovacs, M. (1978). Children's Depression Inventory (CDI). Unpublished manuscript, University of Pittsburgh.
39. Kreisman, D. E., & Joy, V. D. (1974). Family response to the mental illness of a relative: A review of the literature. Schizophrenia Bulletin, 1(10), 34-57.
40. Liber, J. M., van Widenfelt, B. M., Goedhart, A. W., Utens, E. M., van der Leeden, A. J., Markus, M. T., & Treffers, P. D. (2008). Parenting and parental anxiety and depression as predictors of treatment outcome for childhood anxiety disorders: Has the role of fathers been underestimated? Journal of Clinical Child and Adolescent Psychology, 37, 747-758. doi:10.1080/15374410802359692
41. Little, R. J. A., & Rubin, D. B. (2002). Statistical analysis with missing data (2nd ed.). New York, NY: Wiley.
42. MacKinnon, D. P. (2000). Contrasts in multiple mediator models. In J. S. Rose, L. Chassin, C. C. Presson, & S. J. Sherman (Eds.), Multivariate applications in substance use research: New methods for new questions (pp. 141-160). Mahwah, NJ: Erlbaum.
43. MacKinnon, D. P., Krull, J. L., & Lockwood, C. M. (2000). Equivalence of the mediation, confounding, and suppression effect. Prevention Science, 1, 173-181. doi:10.1023/A:1026595011371
44. Mallinckrodt, B., Abraham, W., Wei, M., & Russell, D. (2006). Advances in testing the statistical significance of mediation effects. Journal of Counseling Psychology, 53, 372-378. doi:10.1037/0022-0167.53.3.372
45. Manassis, K., Lee, T. C., Bennett, K., Zhao, X. Y., Mendlowitz, S., Duda, S., . . . Wood, J. J. (2014). Types of parental involvement in CBT with anxious youth: A preliminary meta-analysis. Journal of Consulting and Clinical Psychology. Advance online publication. doi:10.1037/a0036969
46. Montgomery, R. J., Gonyea, J. G., & Hooyman, N. R. (1985). Caregiving and the experience of subjective and objective burden. Family Relations, 34, 19-26. doi:10.2307/583753
47. Nomura, Y., Wickramaratne, P. J., Warner, V., Mufson, L., & Weissman, M. M. (2002). Family discord, parental depression, and psychopathology in offspring: Ten-year follow-up. Journal of the American Academy of Child & Adolescent Psychiatry, 41, 402-409. doi:10.1097/00004583-200204000-00012
48. Norbeck, J. S., Chaftez, L., Skodol-Wilson, H., & Weiss, S. J. (1991). Social support needs of family caregivers of psychiatric patients from three age groups. Nursing Research, 40, 208 -213. doi:10.1097/00006199-199107000-00005
49. Phares, V., Lopez, E., Fields, S., Kamboukos, D., & Duhig, A. M. (2005). Are fathers involved in pediatric psychology treatment and research? Journal of Pediatric Psychology, 30, 631-643. doi:10.1093/jpepsy/jsi050
50. Piacentini, J., Bennett, S., Compton, S. N., Kendall, P. C., Birmaher, B., Albano, A. M., . . . Walkup, J. (2014). 24- and 36-week outcomes for the Child/Adolescent Anxiety Multimodal Study (CAMS). Journal of the American Academy of Child & Adolescent Psychiatry, 53, 297-310. doi:10.1016/j.jaac.2013.11.010
51. Piacentini, J., Peris, T. S., Bergman, R. L., Chang, S., & Jaffer, M. (2007). Functional impairment in childhood OCD: Development and psychometrics properties of the Child Obsessive-Compulsive Impact Scale-Revised (COIS-R). Journal of Clinical Child and Adolescent Psychology, 36, 645-653. doi:10.1080/15374410701662790
52. Pilowsky, D. J., Wickramaratne, P., Talati, A., Tang, M., Hughes, C. W., Garber, J., . . . Weissman, M. M. (2008). Children of depressed mothers 1 year after the initiation of maternal treatment: Findings from the STAR-D-Child study. American Journal of Psychiatry, 165, 1136-1147. doi:10.1176/appi.ajp.2008.07081286
53. Platt, S. D. (1985). Measuring the burden of psychiatric illness on the family: An evaluation of some rating scales. Psychological Medicine, 15, 383-393. doi:10.1017/S0033291700023680
54. Preacher, K. J., & Hayes, A. F. (2008). Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models. Behavior Research Methods, 40, 879-891. doi:10.3758/BRM.40.3.879
55. The Research Units on Pedicatric Psychopharmacology Anxiety Study Group. (2002). The Pediatric Anxiety Rating Scale (PARS): Development and psychometric properties. Journal of the American Academy of Child & Adolescent Psychiatry, 41, 1061-1069. doi:10.1097/00004583-200209000-00006
56. Reinhard, S. C., Gubman, G. D., Horwitz, A. V., & Minsky, S. (1994). Burden Assessment Scale for families of the seriously mentally ill. Evaluation and Program Planning, 17, 261-269. doi:10.1016/0149-7189(94)90004-3
57. Reyno, S. M., & McGrath, P. J. (2006). Predictors of parent training efficacy for child externalizing behavior problems: a meta-analytic review. Journal of Child Psychology and Psychiatry, 47, 99-111. doi: 10.1111/j.1469-7610.2005.01544.x
58. Rucker, D. D., Preacher, K. J., Tormala, Z. L., & Petty, R. E. (2011). Mediation analysis in social psychology: Current practices and new recommendations. Social and Personality Psychology Compass, 5, 359-371. doi:10.1111/j.1751-9004.2011.00355.x
59. Sarason, I. G., Johnson, J. H., & Siegel, J. M. (1978). Assessing the impact of life changes: Development of the Life Experiences Survey. Journal of Consulting and Clinical Psychology, 46, 932-946. doi:10.1037/0022-006X.46.5.932
60. Schleider, J. L., Vélez, C. E., Krause, E. D., & Gillham, J. (2014). Perceived psychological control and anxiety in early adolescents: The mediating role of attributional style. Cognitive Therapy and Research, 38, 71-81. doi:10.1007/s10608-013-9573-9
61. Siegel, J. M., Aneshensel, C. S., Taub, B., Cantwell, D. P., & Driscoll, A. K. (1998). Adolescent depressed mood in a multiethnic sample. Journal of Youth and Adolescence, 27, 413- 427. doi:10.1023/A:1022873601030
62. Silverman, W. K., Kurtines, W. M., Jaccard, J., & Pina, A. A. (2009). Directionality of change in youth anxiety treatment involving parents: An initial examination. Journal of Consulting and Clinical Psychology, 77, 474-485. doi:10.1037/a0015761
63. Silverman, W. K., Pina, A. A., & Viswesvaran, C. (2008). Evidence-based psychosocial treatments for phobic and anxiety disorders in children and adolescents. Journal of Clinical Child and Adolescent Clinical Psychology, 37, 105-130. doi:10.1080/15374410701817907
64. Skinner, H., Steinhauer, P., & Santa-Barbara, J. (1995). Family Assessment Measure-III manual. North Tonawanda, NY: Multi-Health Systems.
65. Skinner, H., Steinhauer, P., & Sitarenios, G. (2000). Family Assessment Measure (FAM) and Process Model of Family Functioning. Journal of Family Therapy, 22, 190-210. doi:10.1111/1467-6427.00146
66. Southam-Gerow, M. A., Kendall, P. C., & Weersing, V. R. (2001). Examining outcome variability: Correlates of treatment response in a child and adolescent anxiety clinic. Journal of Clinical Child Psychology, 30, 422-436. doi:10.1207/S15374424JCCP3003-13
67. Steinhauer, P. D. (1987) The family as a small group: The Process Model of Family Functioning. In T. Jacob (Ed.), Family interaction and psychopathology: Theories, methods, and findings (pp. 67-115). New York, NY: Plenum Press.
68. Steinhauer, P. D., Santa-Barbara, J., & Skinner, H. A. (1984). The Process Model of Family Functioning. Canadian Journal of Psychiatry, 29, 77-88. doi:10.1111/1467- 6427.00146
69. Tzelgov, J., & Henik, A. (1991). Suppression situations in psychological research: Definitions, implications, and applications. Psychological Bulletin, 109, 524-536. doi:10.1037/0033-2909.109.3.524
70. Victor, A. M., Bernat, D. H., Bernstein, G. A., & Layne, A. E. (2007). Effects of parent and family characteristics on treatment outcome of anxious children. Journal of Anxiety Disorders, 21, 835-848. doi: 10.1016/j.janxdis.2006.11.005
71. Walkup, J. T., Albano, A. M., Piacentini, J., Birmaher, B., Compton, S. N., Sherrill, J. T., . . . Kendall, P. C. (2008). Cognitive behavioral therapy, sertraline, or a combination in childhood anxiety. New England Journal of Medicine, 359, 2753-2766. doi:10.1056/NEJMoa0804633
72. Weisz, J. R., Ng, M. N., Rutt, C., Lau, N., & Masland, S. A. (2013). Psychotherapy for children and adolescents. In M. J. Lambert (Ed.), Bergin and Garfield's handbook of psychotherapy and behavior change (6th ed., pp. 541-586). New York, NY: Wiley.
73. Zaider, T. I., Heimberg, R. G., Fresco, D. M., Schneier, F. R., & Liebowitz, M. R. (2003). Evaluation of the Clinical Global Impression Scale among individuals with social anxiety disorder. Psychological Medicine, 33, 611-622. doi:10.1017/S0033291703007414
74. Zhao, X., Lynch, J. G., & Chen, Q. (2010). Reconsidering Baron and Kenny: Myths and truths about mediation analysis. Journal of Consumer Research, 37, 197-206. doi:10.1086/651257