Impaired respiratory function in MELAS-induced pluripotent stem cells with high heteroplasmy levels

FEBS Open Bio

Volumn 5, Issue , 2015, Pages 219-225

  Kodaira, Masaki ^a   Hatakeyama, Hideyuki ^b,c   Yuasa, Shinsuke ^a   Seki, Tomohisa ^a   Egashira, Toru ^a   Tohyama, Shugo ^a   Kuroda, Yusuke ^a   Tanaka, Atsushi ^a   Okata, Shinichiro ^a   Hashimoto, Hisayuki ^a   Kusumoto, Dai ^a   Kunitomi, Akira ^a   Takei, Makoto ^a   Kashimura, Shin ^a   Suzuki, Tomoyuki ^a   Yozu, Gakuto ^a   Shimojima, Masaya ^a   Motoda, Chikaaki ^a   Hayashiji, Nozomi ^a   Saito, Yuki ^a   Goto, Yu ichi ^b,c   Fukuda, Keiichi ^a   more..

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Disease modeling; IPS cell; MELAS; Mitochondrial disease

Indexed keywords

MITOCHONDRIAL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; COPY NUMBER VARIATION; ENZYME ACTIVITY; ENZYME DEFECT; FIBROBLAST; HETEROPLASMY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MELAS SYNDROME; MITOCHONDRIAL RESPIRATION; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; RESPIRATORY FUNCTION DISORDER; SKIN BIOPSY; TERATOMA;

EID: 84925695495     PISSN: None     EISSN: 22115463     Source Type: Journal    
DOI: 10.1016/j.fob.2015.03.008     Document Type: Article

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