Human umbilical cord blood mesenchymal stem cell-derived PGE2 and TGF-β1 alleviate atopic dermatitis by reducing mast cell degranulation

Stem Cells

Volumn 33, Issue 4, 2015, Pages 1254-1266

  Kim, Hyung Sik ^a   Yun, Jun Won ^a,b   Shin, Tae Hoon ^a   Lee, Sung Hoon ^a   Lee, Byung Chul ^a   Yu, Kyung Rok ^a   Seo, Yoojin ^a   Lee, Seunghee ^a   Kang, Tae Wook ^a   Choi, Soon Won ^a   Seo, Kwang Won ^a   Kang, Kyung Sun ^a  

^a Seoul National University   (South Korea)

^b Seoul National University Hospital   (South Korea)

Author keywords

Atopic dermatitis; Immunomodulation; Mast cell degranulation; Mesenchymal stem cells; NOD2

Indexed keywords

BETA N ACETYLHEXOSAMINIDASE; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CYCLOOXYGENASE 2; INTERLEUKIN 4; PROSTAGLANDIN E2; STAT6 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATOPIC DERMATITIS; CELL ACTIVATION; CELL CONTACT; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DERMATOPHAGOIDES FARINAE; DISEASE SEVERITY; DOWN REGULATION; ENZYME ASSAY; HUMAN; HUMAN CELL; MAST CELL DEGRANULATION; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UMBILICAL CORD BLOOD; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DEGRANULATION; MAST CELL; MESENCHYMAL STROMA CELL; METABOLISM; PHYSIOLOGY; PROCEDURES; SUBCUTANEOUS DRUG ADMINISTRATION; TRANSPLANTATION; UMBILICAL VEIN ENDOTHELIAL CELL;

DERMATOPHAGOIDES FARINAE; MURINAE; MUS;

ANIMALS; CELL DEGRANULATION; CELLS, CULTURED; DERMATITIS, ATOPIC; DINOPROSTONE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INJECTIONS, SUBCUTANEOUS; MAST CELLS; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84925674675     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1913     Document Type: Article

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