Long-term in Vivo clearance of gadolinium-based AGuIX nanoparticles and their biocompatibility after systemic injection

ACS Nano

Volumn 9, Issue 3, 2015, Pages 2477-2488

  Sancey, Lucie ^a   Kotb, Shady ^a   Truillet, Charles ^a   Appaix, Florence ^b   Marais, Arthur ^a   Thomas, Eloïse ^a   Van Der Sanden, Boudewijn ^b   Klein, Jean Philippe ^c   Laurent, Blandine ^c   Cottier, Michèle ^c   Antoine, Rodolphe ^a   Dugourd, Philippe ^a   Panczer, Gérard ^a   Lux, François ^a   Perriat, Pascal ^d   Motto Ros, Vincent ^a   Tillement, Olivier ^a  

^a UNIVERSITÉ LYON 1   (France)

^b GRENOBLE INSTITUT DES NEUROSCIENCES   (France)

^c Jean Monnet University   (France)

^d CNRS   (France)

Author keywords

gadolinium; laser induced breakdown spectroscopy; nanoparticle; renal function; theranostic; toxicity; two photon microscopy

Indexed keywords

BIOCOMPATIBILITY; ELECTRODEPOSITION; ELECTROSPRAY IONIZATION; GADOLINIUM; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; INDUCTIVELY COUPLED PLASMA; LASER INDUCED BREAKDOWN SPECTROSCOPY; MASS SPECTROMETRY; NANOPARTICLES; PHOTOIONIZATION; PHOTONS; SYNTHESIS (CHEMICAL); THERANOSTICS; TOXICITY; X RAYS;

COMPLEMENTARY METHODS; ELECTROSPRAY IONIZATION MASS SPECTROMETRY; INDUCTIVELY COUPLED PLASMA-OPTICAL EMISSION SPECTROMETRY; INFORMATION CONCERNING; LASERINDUCED BREAKDOWN SPECTROSCOPY (LIBS); RENAL FUNCTIONS; THERANOSTIC; TWO PHOTON MICROSCOPY;

OPTICAL EMISSION SPECTROSCOPY;

BIOMATERIAL; CONTRAST MEDIUM; GADOLINIUM; METAL NANOPARTICLE;

ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG EFFECTS; HUMAN; INJECTION; KIDNEY CORTEX; KINETICS; METABOLISM; MOUSE; SAFETY; TRANSPORT AT THE CELLULAR LEVEL; X RAY;

ANIMALS; BIOCOMPATIBLE MATERIALS; BIOLOGICAL TRANSPORT; CONTRAST MEDIA; GADOLINIUM; HUMANS; INJECTIONS; KIDNEY CORTEX; KINETICS; METAL NANOPARTICLES; MICE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; SAFETY; X-RAYS;

EID: 84925667150     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.5b00552     Document Type: Article

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