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Volumn 6, Issue 8, 2015, Pages 5846-5859

CD133+ ovarian cancer stem-like cells promote non-stem cancer cell metastasis via CCL5 induced epithelial-mesenchymal transition

Author keywords

cancer stem like cells; Chemokine (C C motif) ligand 5; Epithelial mesenchymal transition; NF B; Non cancer stem like cells

Indexed keywords

CD133 ANTIGEN; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR5; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PYRROLIDINE DITHIOCARBAMATE; RANTES; CCL5 PROTEIN, HUMAN; CCL5 PROTEIN, MOUSE; GLYCOPROTEIN; LEUKOCYTE ANTIGEN; PEPTIDE; PROM1 PROTEIN, HUMAN; PROM1 PROTEIN, MOUSE;

EID: 84925584281     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3462     Document Type: Article
Times cited : (74)

References (54)
  • 2
    • 84873582060 scopus 로고    scopus 로고
    • Integrated analyses identify a master microRNA regulatory network for the mesenchymal subtype in serous ovarian cancer
    • Yang D, Sun Y, Hu L, Zheng H, Ji P, Pecot CV et al. Integrated analyses identify a master microRNA regulatory network for the mesenchymal subtype in serous ovarian cancer. Cancer cell. 2013;23:186-99.
    • (2013) Cancer cell , vol.23 , pp. 186-199
    • Yang, D.1    Sun, Y.2    Hu, L.3    Zheng, H.4    Ji, P.5    Pecot, C.V.6
  • 4
    • 84884354300 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells enhance stemness of cancer cells by inducing microRNA101 and suppressing the corepressor CtBP2
    • Cui TX, Kryczek I, Zhao L, Zhao E, Kuick R, Roh MH et al. Myeloid-derived suppressor cells enhance stemness of cancer cells by inducing microRNA101 and suppressing the corepressor CtBP2. Immunity. 2013; 39:611-21.
    • (2013) Immunity , vol.39 , pp. 611-621
    • Cui, T.X.1    Kryczek, I.2    Zhao, L.3    Zhao, E.4    Kuick, R.5    Roh, M.H.6
  • 5
    • 84881500995 scopus 로고    scopus 로고
    • Ovarian cancer stem cells are enriched in side population and aldehyde dehydrogenase bright overlapping population
    • Yasuda K, Torigoe T, Morita R, Kuroda T, Takahashi A, Matsuzaki J et al. Ovarian cancer stem cells are enriched in side population and aldehyde dehydrogenase bright overlapping population. PLoS One. 2013; 8:e68187.
    • (2013) PLoS One , vol.8
    • Yasuda, K.1    Torigoe, T.2    Morita, R.3    Kuroda, T.4    Takahashi, A.5    Matsuzaki, J.6
  • 7
    • 79957917044 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase in combination with CD133 defines angiogenic ovarian cancer stem cells that portend poor patient survival
    • Silva IA, Bai S, McLean K, Yang K, Griffith K, Thomas D et al. Aldehyde dehydrogenase in combination with CD133 defines angiogenic ovarian cancer stem cells that portend poor patient survival. Cancer Res. 2011; 71:3991-01.
    • (2011) Cancer Res , vol.71 , pp. 3991-4001
    • Silva, I.A.1    Bai, S.2    McLean, K.3    Yang, K.4    Griffith, K.5    Thomas, D.6
  • 9
    • 49249091523 scopus 로고    scopus 로고
    • Identification and characterization of ovarian cancer-initiating cells from primary human tumors
    • Zhang S, Balch C, Chan MW, Lai HC, Matei D, Schilder JM et al. Identification and characterization of ovarian cancer-initiating cells from primary human tumors. Cancer Res. 2008; 68:4311-20.
    • (2008) Cancer Res , vol.68 , pp. 4311-4320
    • Zhang, S.1    Balch, C.2    Chan, M.W.3    Lai, H.C.4    Matei, D.5    Schilder, J.M.6
  • 10
    • 77952240931 scopus 로고    scopus 로고
    • CD24+ cells from hierarchically organized ovarian cancer are enriched in cancer stem cells
    • Gao MQ, Choi YP, Kang S, Youn JH, Cho NH. CD24+ cells from hierarchically organized ovarian cancer are enriched in cancer stem cells. Oncogene. 2010; 29:2672-80.
    • (2010) Oncogene , vol.29 , pp. 2672-2680
    • Gao, M.Q.1    Choi, Y.P.2    Kang, S.3    Youn, J.H.4    Cho, N.H.5
  • 11
    • 33746625091 scopus 로고    scopus 로고
    • Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness
    • Szotek PP, Pieretti-Vanmarcke R, Masiakos PT, Dinulescu DM, Connolly D, Foster R et al. Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness. Proc Natl Acad Sci USA. 2006;103:11154-9.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 11154-11159
    • Szotek, P.P.1    Pieretti-Vanmarcke, R.2    Masiakos, P.T.3    Dinulescu, D.M.4    Connolly, D.5    Foster, R.6
  • 12
    • 48649101859 scopus 로고    scopus 로고
    • The side population of ovarian cancer cells is a primary target of IFN-alpha antitumor effects
    • Moserle L, Indraccolo S, Ghisi M, Frasson C, Fortunato E, Canevari S et al. The side population of ovarian cancer cells is a primary target of IFN-alpha antitumor effects. Cancer Res. 2008; 68:5658-68.
    • (2008) Cancer Res , vol.68 , pp. 5658-5668
    • Moserle, L.1    Indraccolo, S.2    Ghisi, M.3    Frasson, C.4    Fortunato, E.5    Canevari, S.6
  • 13
    • 58249095085 scopus 로고    scopus 로고
    • Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells
    • Baba T, Convery PA, Matsumura N, Whitaker RS, Kondoh E, Perry T et al. Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells. Oncogene. 2009; 28: 209-18.
    • (2009) Oncogene , vol.28 , pp. 209-218
    • Baba, T.1    Convery, P.A.2    Matsumura, N.3    Whitaker, R.S.4    Kondoh, E.5    Perry, T.6
  • 14
    • 84866640259 scopus 로고    scopus 로고
    • Autocrine CCL5 signaling promotes invasion and migration of CD133+ ovarian cancer stem-like cells via NF-kappaB-mediated MMP-9 upregulation
    • Long H, Xie R, Xiang T, Zhao Z, Lin S, Liang Z et al. Autocrine CCL5 signaling promotes invasion and migration of CD133+ ovarian cancer stem-like cells via NF-kappaB-mediated MMP-9 upregulation. Stem cells. 2012;30:2309-19.
    • (2012) Stem cells , vol.30 , pp. 2309-2319
    • Long, H.1    Xie, R.2    Xiang, T.3    Zhao, Z.4    Lin, S.5    Liang, Z.6
  • 15
    • 84879996033 scopus 로고    scopus 로고
    • MicroRNA-200c overexpression inhibits tumorigenicity and metastasis of CD117+CD44+ ovarian cancer stem cells by regulating epithelial-mesenchymal transition
    • Chen D, Zhang Y, Wang J, Chen J, Yang C, Cai K et al. MicroRNA-200c overexpression inhibits tumorigenicity and metastasis of CD117+CD44+ ovarian cancer stem cells by regulating epithelial-mesenchymal transition. J Ovarian Res. 2013; 6:50.
    • (2013) J Ovarian Res , vol.6 , pp. 50
    • Chen, D.1    Zhang, Y.2    Wang, J.3    Chen, J.4    Yang, C.5    Cai, K.6
  • 16
    • 79958265710 scopus 로고    scopus 로고
    • Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast
    • Scheel C, Eaton EN, Li SH, Chaffer CL, Reinhardt F, Kah KJ et al. Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell. 2011; 145:926-40.
    • (2011) Cell , vol.145 , pp. 926-940
    • Scheel, C.1    Eaton, E.N.2    Li, S.H.3    Chaffer, C.L.4    Reinhardt, F.5    Kah, K.J.6
  • 17
    • 79955954699 scopus 로고    scopus 로고
    • An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition
    • Gregory PA, Bracken CP, Smith E, Bert AG, Wright JA, Roslan S et al. An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol Biol Cell. 2011; 22:1686-98.
    • (2011) Mol Biol Cell , vol.22 , pp. 1686-1698
    • Gregory, P.A.1    Bracken, C.P.2    Smith, E.3    Bert, A.G.4    Wright, J.A.5    Roslan, S.6
  • 18
    • 84885079983 scopus 로고    scopus 로고
    • FGFR4 promotes stroma-induced epithelial-to-mesenchymal transition in colorectal cancer
    • Liu R, Li J, Xie K, Zhang T, Lei Y, Chen Y et al. FGFR4 promotes stroma-induced epithelial-to-mesenchymal transition in colorectal cancer. Cancer Res. 2013;73:5926-35.
    • (2013) Cancer Res , vol.73 , pp. 5926-5935
    • Liu, R.1    Li, J.2    Xie, K.3    Zhang, T.4    Lei, Y.5    Chen, Y.6
  • 19
    • 84893005680 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and migration of prostate cancer stem cells is driven by cancer-associated fibroblasts in an HIF-1α/β-catenin-dependent pathway
    • Luo Y, Lan L, Jiang YG, Zhao JH, Li MC, Wei NB et al. Epithelial-mesenchymal transition and migration of prostate cancer stem cells is driven by cancer-associated fibroblasts in an HIF-1α/β-catenin-dependent pathway. Mol Cells. 2013; 36:138-44.
    • (2013) Mol Cells , vol.36 , pp. 138-144
    • Luo, Y.1    Lan, L.2    Jiang, Y.G.3    Zhao, J.H.4    Li, M.C.5    Wei, N.B.6
  • 20
    • 84862823626 scopus 로고    scopus 로고
    • Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors
    • Bonde AK, Tischler V, Kumar S, Soltermann A, Schwendener RA. Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors. BMC Cancer. 2012;12:35.
    • (2012) BMC Cancer , vol.12 , pp. 35
    • Bonde, A.K.1    Tischler, V.2    Kumar, S.3    Soltermann, A.4    Schwendener, R.A.5
  • 21
    • 84869875206 scopus 로고    scopus 로고
    • IL-1β promotes stemness and invasiveness of colon cancer cells through Zeb1 activation
    • Yijing Li, Lei Wang, Loretta Pappan, Amy Galliher-Beckley and Jishu Shi. IL-1β promotes stemness and invasiveness of colon cancer cells through Zeb1 activation. Mol Cancer. 2012; 11: 87
    • (2012) Mol Cancer , vol.11 , pp. 87
    • Li, Y.1    Wang, L.2    Pappan, L.3    Galliher-Beckley, A.4    Shi, J.5
  • 22
    • 79960952144 scopus 로고    scopus 로고
    • IL-8 signaling plays a critical role in the epithelial-mesenchymal transition of human carcinoma cells
    • Fernando RI, Castillo MD, Litzinger M, Hamilton DH, Palena C. IL-8 signaling plays a critical role in the epithelial-mesenchymal transition of human carcinoma cells. Cancer Res. 2011; 71: 5296-306.
    • (2011) Cancer Res , vol.71 , pp. 5296-5306
    • Fernando, R.I.1    Castillo, M.D.2    Litzinger, M.3    Hamilton, D.H.4    Palena, C.5
  • 23
    • 34347330516 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition induced by the stromal cell-derived factor-1/CXCR4 system in oral squamous cell carcinoma cells
    • Onoue T, Uchida D, Begum NM, Tomizuka Y, Yoshida H, Sato M. Epithelial-mesenchymal transition induced by the stromal cell-derived factor-1/CXCR4 system in oral squamous cell carcinoma cells. Int J Oncol. 2006;29:1133-8.
    • (2006) Int J Oncol , vol.29 , pp. 1133-1138
    • Onoue, T.1    Uchida, D.2    Begum, N.M.3    Tomizuka, Y.4    Yoshida, H.5    Sato, M.6
  • 24
    • 34948896045 scopus 로고    scopus 로고
    • Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
    • Karnoub AE, Dash AB, Vo AP, Sullivan A, Brooks MW, Bell GW et al. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature. 2007;449:557-63.
    • (2007) Nature , vol.449 , pp. 557-563
    • Karnoub, A.E.1    Dash, A.B.2    Vo, A.P.3    Sullivan, A.4    Brooks, M.W.5    Bell, G.W.6
  • 25
    • 69049098045 scopus 로고    scopus 로고
    • Tissue resident stem cells produce CCL5 under the influence of cancer cells and thereby promote breast cancer cell invasion
    • Pinilla S, Alt E, Abdul Khalek FJ, Jotzu C, Muehlberg F, Beckmann C et al. Tissue resident stem cells produce CCL5 under the influence of cancer cells and thereby promote breast cancer cell invasion. Cancer letters. 2009;284:80-5.
    • (2009) Cancer letters , vol.284 , pp. 80-85
    • Pinilla, S.1    Alt, E.2    Abdul Khalek, F.J.3    Jotzu, C.4    Muehlberg, F.5    Beckmann, C.6
  • 26
    • 84871528926 scopus 로고    scopus 로고
    • MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer
    • Mitra AK, Zillhardt M, Hua Y, Tiwari P, Murmann AE, Peter ME et al. MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer. Cancer Discov. 2012; 2:1100-8.
    • (2012) Cancer Discov , vol.2 , pp. 1100-1108
    • Mitra, A.K.1    Zillhardt, M.2    Hua, Y.3    Tiwari, P.4    Murmann, A.E.5    Peter, M.E.6
  • 27
    • 84874646861 scopus 로고    scopus 로고
    • A novel role of hematopoietic CCL5 in promoting triple-negative mammary tumor progression by regulating generation of myeloid-derived suppressor cells
    • Zhang Y, Lv D, Kim HJ, Kurt RA, Bu W, Li Y et al. A novel role of hematopoietic CCL5 in promoting triple-negative mammary tumor progression by regulating generation of myeloid-derived suppressor cells. Cell Res. 2013;23:394-408.
    • (2013) Cell Res , vol.23 , pp. 394-408
    • Zhang, Y.1    Lv, D.2    Kim, H.J.3    Kurt, R.A.4    Bu, W.5    Li, Y.6
  • 28
    • 84871127292 scopus 로고    scopus 로고
    • Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth
    • Schlecker E, Stojanovic A, Eisen C, Quack C, Falk CS, Umansky V et al. Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth. Journal of immunology. 2012;189:5602-11.
    • (2012) Journal of immunology , vol.189 , pp. 5602-5611
    • Schlecker, E.1    Stojanovic, A.2    Eisen, C.3    Quack, C.4    Falk, C.S.5    Umansky, V.6
  • 29
    • 80051703591 scopus 로고    scopus 로고
    • Maximal T cell-mediated antitumor responses rely upon CCR5 expression in both CD4(+) and CD8(+) T cells
    • Gonzalez-Martin A, Gomez L, Lustgarten J, Mira E, Manes S. Maximal T cell-mediated antitumor responses rely upon CCR5 expression in both CD4(+) and CD8(+) T cells. Cancer research. 2011;71:5455-66.
    • (2011) Cancer research , vol.71 , pp. 5455-5466
    • Gonzalez-Martin, A.1    Gomez, L.2    Lustgarten, J.3    Mira, E.4    Manes, S.5
  • 30
    • 11244321518 scopus 로고    scopus 로고
    • Up-regulation of CC chemokine, CCL3L1, and receptors, CCR3, CCR5 in human glioblastoma that promotes cell growth
    • Kouno J, Nagai H, Nagahata T, Onda M, Yamaguchi H, Adachi K et al. Up-regulation of CC chemokine, CCL3L1, and receptors, CCR3, CCR5 in human glioblastoma that promotes cell growth. Journal of neuro-oncology. 2004;70:301-7.
    • (2004) Journal of neuro-oncology , vol.70 , pp. 301-307
    • Kouno, J.1    Nagai, H.2    Nagahata, T.3    Onda, M.4    Yamaguchi, H.5    Adachi, K.6
  • 31
    • 84863280130 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition induced by TNF-alpha requires NF-kappaB-mediated transcriptional upregulation of Twist1
    • Li CW, Xia W, Huo L, Lim SO, Wu Y, Hsu JL et al. Epithelial-mesenchymal transition induced by TNF-alpha requires NF-kappaB-mediated transcriptional upregulation of Twist1. Cancer research. 2012;72:1290-300.
    • (2012) Cancer research , vol.72 , pp. 1290-1300
    • Li, C.W.1    Xia, W.2    Huo, L.3    Lim, S.O.4    Wu, Y.5    Hsu, J.L.6
  • 32
    • 76549111028 scopus 로고    scopus 로고
    • NF-kappaB-dependent plasticity of the epithelial to mesenchymal transition induced by Von Hippel-Lindau inactivation in renal cell carcinomas
    • Pantuck AJ, An J, Liu H, Rettig MB. NF-kappaB-dependent plasticity of the epithelial to mesenchymal transition induced by Von Hippel-Lindau inactivation in renal cell carcinomas. Cancer research. 2010;70:752-61.
    • (2010) Cancer research , vol.70 , pp. 752-761
    • Pantuck, A.J.1    An, J.2    Liu, H.3    Rettig, M.B.4
  • 33
    • 84874646861 scopus 로고    scopus 로고
    • A novel role of hematopoietic CCL5 in promoting triple-negative mammary tumor progression by regulating generation of myeloid-derived suppressor cells
    • Zhang Y, Lv D, Kim HJ, Kurt RA, Bu W, Li Y et al. A novel role of hematopoietic CCL5 in promoting triple-negative mammary tumor progression by regulating generation of myeloid-derived suppressor cells. Cell research. 2013;23:394-408.
    • (2013) Cell research , vol.23 , pp. 394-408
    • Zhang, Y.1    Lv, D.2    Kim, H.J.3    Kurt, R.A.4    Bu, W.5    Li, Y.6
  • 34
    • 65349092794 scopus 로고    scopus 로고
    • Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion
    • Wu Y, Deng J, Rychahou PG, Qiu S, Evers BM, Zhou BP. Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion. Cancer cell. 2009;15:416-28.
    • (2009) Cancer cell , vol.15 , pp. 416-428
    • Wu, Y.1    Deng, J.2    Rychahou, P.G.3    Qiu, S.4    Evers, B.M.5    Zhou, B.P.6
  • 37
    • 65249184461 scopus 로고    scopus 로고
    • CD133-expressing stem cells associated with ovarian metastases establish an endothelial hierarchy and contribute to tumor vasculature
    • Kusumbe AP, Mali AM, Bapat SA. CD133-expressing stem cells associated with ovarian metastases establish an endothelial hierarchy and contribute to tumor vasculature. Stem Cells. 2009 ;27:498-508
    • (2009) Stem Cells , vol.27 , pp. 498-508
    • Kusumbe, A.P.1    Mali, A.M.2    Bapat, S.A.3
  • 39
    • 84862832781 scopus 로고    scopus 로고
    • CCL5, CCR1 and CCR5 in murine glioblastoma: immune cell infiltration and survival rates are not dependent on individual expression of either CCR1 or CCR5
    • Pham K, Luo D, Liu C, Harrison JK. CCL5, CCR1 and CCR5 in murine glioblastoma: immune cell infiltration and survival rates are not dependent on individual expression of either CCR1 or CCR5. Journal of neuroimmunology. 2012;246:10-7.
    • (2012) Journal of neuroimmunology , vol.246 , pp. 10-17
    • Pham, K.1    Luo, D.2    Liu, C.3    Harrison, J.K.4
  • 40
    • 66149171486 scopus 로고    scopus 로고
    • Nuclear factor-kappaB-mediated transforming growth factor-beta-induced expression of vimentin is an independent predictor of biochemical recurrence after radical prostatectomy
    • Zhang Q, Helfand BT, Jang TL, Zhu LJ, Chen L, Yang XJ et al. Nuclear factor-kappaB-mediated transforming growth factor-beta-induced expression of vimentin is an independent predictor of biochemical recurrence after radical prostatectomy. Clinical cancer research. 2009;15:3557-67.
    • (2009) Clinical cancer research , vol.15 , pp. 3557-3567
    • Zhang, Q.1    Helfand, B.T.2    Jang, T.L.3    Zhu, L.J.4    Chen, L.5    Yang, X.J.6
  • 41
    • 79961006281 scopus 로고    scopus 로고
    • Human ovarian carcinoma-associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production
    • McLean K, Gong Y, Choi Y, Deng N, Yang K, Bai S et al. Human ovarian carcinoma-associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production. J Clin Invest. 2011; 121:3206-19.
    • (2011) J Clin Invest , vol.121 , pp. 3206-3219
    • McLean, K.1    Gong, Y.2    Choi, Y.3    Deng, N.4    Yang, K.5    Bai, S.6
  • 42
    • 79951852902 scopus 로고    scopus 로고
    • Ovarian cancer-associated fibroblasts contribute to epithelial ovarian carcinoma metastasis by promoting angiogenesis, lymphangiogenesis and tumor cell invasion
    • Zhang Y, Tang H, Cai J, Zhang T, Guo J, Feng D et al. Ovarian cancer-associated fibroblasts contribute to epithelial ovarian carcinoma metastasis by promoting angiogenesis, lymphangiogenesis and tumor cell invasion. Cancer Lett. 2011; 303:47-55.
    • (2011) Cancer Lett , vol.303 , pp. 47-55
    • Zhang, Y.1    Tang, H.2    Cai, J.3    Zhang, T.4    Guo, J.5    Feng, D.6
  • 43
    • 80255137100 scopus 로고    scopus 로고
    • Expression of aldehyde dehydrogenase and CD133 defines ovarian cancer stem cells
    • Kryczek I, Liu S, Roh M, Vatan L, Szeliga W, Wei S et al. Expression of aldehyde dehydrogenase and CD133 defines ovarian cancer stem cells. Int J Cancer. 2012;130:29-39.
    • (2012) Int J Cancer , vol.130 , pp. 29-39
    • Kryczek, I.1    Liu, S.2    Roh, M.3    Vatan, L.4    Szeliga, W.5    Wei, S.6
  • 44
    • 36849078711 scopus 로고    scopus 로고
    • let-7 regulates self renewal and tumorigenicity of breast cancer cells
    • Yu F, Yao H, Zhu P, Zhang X, Pan Q, Gong C et al. let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell. 2007;131:1109-23.
    • (2007) Cell , vol.131 , pp. 1109-1123
    • Yu, F.1    Yao, H.2    Zhu, P.3    Zhang, X.4    Pan, Q.5    Gong, C.6
  • 45
    • 77956178360 scopus 로고    scopus 로고
    • EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
    • Singh A, Settleman J. EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer. Oncogene. 2010;29:4741-51.
    • (2010) Oncogene , vol.29 , pp. 4741-4751
    • Singh, A.1    Settleman, J.2
  • 46
    • 79953689605 scopus 로고    scopus 로고
    • Cancer Stem Cells and Epithelial-to-Mesenchymal Transition (EMT)-Phenotypic Cells: Are They Cousins or Twins?
    • Kong D, Li Y, Wang Z, Sarkar FH. Cancer Stem Cells and Epithelial-to-Mesenchymal Transition (EMT)-Phenotypic Cells: Are They Cousins or Twins? Cancers. 2011;3:716-29.
    • (2011) Cancers , vol.3 , pp. 716-729
    • Kong, D.1    Li, Y.2    Wang, Z.3    Sarkar, F.H.4
  • 47
    • 84879983245 scopus 로고    scopus 로고
    • Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity
    • Chaffer CL, Marjanovic ND, Lee T, Bell G, Kleer CG, Reinhardt F et al. Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity. Cell. 2013;154:61-74.
    • (2013) Cell , vol.154 , pp. 61-74
    • Chaffer, C.L.1    Marjanovic, N.D.2    Lee, T.3    Bell, G.4    Kleer, C.G.5    Reinhardt, F.6
  • 48
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell. 2008;133:704-15.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.J.3    Eaton, E.N.4    Ayyanan, A.5    Zhou, A.Y.6
  • 50
    • 84863012785 scopus 로고    scopus 로고
    • CD146, an epithelial-mesenchymal transition inducer, is associated with triple-negative breast cancer
    • Zeng Q, Li W, Lu D, Wu Z, Duan H, Luo Y et al. CD146, an epithelial-mesenchymal transition inducer, is associated with triple-negative breast cancer. Proc Natl Acad Sci USA. 2012;109:1127-32.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 1127-1132
    • Zeng, Q.1    Li, W.2    Lu, D.3    Wu, Z.4    Duan, H.5    Luo, Y.6
  • 51
    • 84875320058 scopus 로고    scopus 로고
    • Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden
    • Abubaker K, Latifi A, Luwor R, Nazaretian S, Zhu H, Quinn MA et al. Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden. Mol Cancer. 2013; 12:24.
    • (2013) Mol Cancer , vol.12 , pp. 24
    • Abubaker, K.1    Latifi, A.2    Luwor, R.3    Nazaretian, S.4    Zhu, H.5    Quinn, M.A.6
  • 52
    • 84869379939 scopus 로고    scopus 로고
    • The role of cancer stem cells in breast cancer initiation and progression: potential cancer stem cell-directed therapies
    • Economopoulou P, Kaklamani VG, Siziopikou K. The role of cancer stem cells in breast cancer initiation and progression: potential cancer stem cell-directed therapies. The oncologist. 2012;17:1394-401.
    • (2012) The oncologist , vol.17 , pp. 1394-1401
    • Economopoulou, P.1    Kaklamani, V.G.2    Siziopikou, K.3
  • 54
    • 0033956798 scopus 로고    scopus 로고
    • Genetic and phenotypic changes associated with the acquisition of tumorigenicity in human bladder cancer
    • Gildea JJ, Golden WL, Harding MA, Theodorescu D. Genetic and phenotypic changes associated with the acquisition of tumorigenicity in human bladder cancer. Genes Chromosomes Cancer. 2000; 27:252-63.
    • (2000) Genes Chromosomes Cancer , vol.27 , pp. 252-263
    • Gildea, J.J.1    Golden, W.L.2    Harding, M.A.3    Theodorescu, D.4


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