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Volumn 291, Issue 5, 2015, Pages 1181-1186

Evaluation of ovarian function and metabolic factors in women affected by polycystic ovary syndrome after treatment with d-Chiro-Inositol

Author keywords

D Chiro Inositol; Metabolic factors; Ovarian function; Polycystic Ovary Syndrome

Indexed keywords

ANDROSTENEDIONE; DEXTRO CHIRO INOSITOL; FOLIC ACID; FOLLITROPIN; GLUCOSE; INOSITOL DERIVATIVE; INSULIN; LUTEINIZING HORMONE; PRASTERONE SULFATE; PROLACTIN; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE; UNCLASSIFIED DRUG; GLUCOSE BLOOD LEVEL; INOSITOL; VITAMIN B COMPLEX;

EID: 84925534174     PISSN: 09320067     EISSN: 14320711     Source Type: Journal    
DOI: 10.1007/s00404-014-3552-6     Document Type: Article
Times cited : (69)

References (56)
  • 1
    • 0346725827 scopus 로고    scopus 로고
    • Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome
    • Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group (2004) Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril 81:19–25
    • (2004) Fertil Steril , vol.81 , pp. 19-25
    • Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group1
  • 2
    • 2942642477 scopus 로고    scopus 로고
    • The prevalence and features of the polycystic ovary syndrome in an unselected population
    • COI: 1:CAS:528:DC%2BD2cXmtlGqurs%3D, PID: 15181052
    • Azziz R, Woods KS, Reyna R, Key TJ, Knochenhauer ES, Yildiz BO (2004) The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab 89:2745–2749
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 2745-2749
    • Azziz, R.1    Woods, K.S.2    Reyna, R.3    Key, T.J.4    Knochenhauer, E.S.5    Yildiz, B.O.6
  • 3
    • 34548039205 scopus 로고    scopus 로고
    • Polycystic ovary syndrome
    • COI: 1:CAS:528:DC%2BD2sXpsFWrtrk%3D, PID: 17720020
    • Norman RJ, Dewailly D, Legro RS, Hickey TE (2007) Polycystic ovary syndrome. Lancet 370:685–697
    • (2007) Lancet , vol.370 , pp. 685-697
    • Norman, R.J.1    Dewailly, D.2    Legro, R.S.3    Hickey, T.E.4
  • 4
    • 0022351373 scopus 로고
    • Ovulatory disorders in women with polycystic ovary syndrome
    • COI: 1:STN:280:DyaL28%2FlsVehuw%3D%3D, PID: 3933879
    • Franks S, Adams J, Mason H, Polson D (1985) Ovulatory disorders in women with polycystic ovary syndrome. Clin Obstet Gynaecol 12:605–632
    • (1985) Clin Obstet Gynaecol , vol.12 , pp. 605-632
    • Franks, S.1    Adams, J.2    Mason, H.3    Polson, D.4
  • 5
    • 0032948363 scopus 로고    scopus 로고
    • Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: a prospective, controlled study in 254 affected women
    • COI: 1:CAS:528:DyaK1MXmslWltA%3D%3D, PID: 9920077
    • Legro RS, Kunselman AR, Dodson WC, Dunaif A (1999) Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: a prospective, controlled study in 254 affected women. J Clin Endocrinol Metab 84:165–169
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 165-169
    • Legro, R.S.1    Kunselman, A.R.2    Dodson, W.C.3    Dunaif, A.4
  • 6
    • 0029796476 scopus 로고    scopus 로고
    • Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome
    • COI: 1:CAS:528:DyaK28XlvVWktr0%3D, PID: 8687515
    • Nestler JE, Jakubowicz DJ (1996) Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome. N Engl J Med 335:617–623
    • (1996) N Engl J Med , vol.335 , pp. 617-623
    • Nestler, J.E.1    Jakubowicz, D.J.2
  • 7
    • 0030783316 scopus 로고    scopus 로고
    • Lean women with polycystic ovary syndrome respond to insulin reduction with decreases in ovarian P450c17 alpha activity and serum androgens
    • COI: 1:CAS:528:DyaK2sXnvFyktLw%3D, PID: 9398716
    • Nestler JE, Jakubowicz DJ (1997) Lean women with polycystic ovary syndrome respond to insulin reduction with decreases in ovarian P450c17 alpha activity and serum androgens. J Clin Endocrinol Metab 82:4075–4079
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 4075-4079
    • Nestler, J.E.1    Jakubowicz, D.J.2
  • 8
    • 0024361382 scopus 로고
    • Polycystic ovary syndrome. A changing perspective
    • COI: 1:CAS:528:DyaL1MXltFaru7c%3D
    • Franks S (1989) Polycystic ovary syndrome. A changing perspective. Clin Endocrinol (Oxf) 31:87–120
    • (1989) Clin Endocrinol (Oxf) , vol.31 , pp. 87-120
    • Franks, S.1
  • 9
    • 0030228354 scopus 로고    scopus 로고
    • Influence of androgenicity on adipocytes and precursor cells in female rats
    • COI: 1:CAS:528:DyaK28XmtF2qtL0%3D, PID: 8885211
    • James RG, Krakower GR, Kissebah AH (1996) Influence of androgenicity on adipocytes and precursor cells in female rats. Obes Res 4:463–470
    • (1996) Obes Res , vol.4 , pp. 463-470
    • James, R.G.1    Krakower, G.R.2    Kissebah, A.H.3
  • 10
    • 38549123824 scopus 로고    scopus 로고
    • Androgens and insulin–two key players in polycystic ovary syndrome. Recent concepts in the pathophysiology and genetics of polycystic ovary syndrome
    • PID: 18209494
    • Schuring AN, Schulte N, Sonntag B, Kiesel L (2008) Androgens and insulin–two key players in polycystic ovary syndrome. Recent concepts in the pathophysiology and genetics of polycystic ovary syndrome. Gynakol Geburtshilfliche Rundsch 48:9–15
    • (2008) Gynakol Geburtshilfliche Rundsch , vol.48 , pp. 9-15
    • Schuring, A.N.1    Schulte, N.2    Sonntag, B.3    Kiesel, L.4
  • 11
    • 0023905126 scopus 로고
    • Serum inhibin levels in polycystic ovary syndrome: basal levels and response to luteinizing hormone-releasing hormone agonist and exogenous gonadotropin administration
    • COI: 1:STN:280:DyaL1c7lsVSnsw%3D%3D, PID: 3126215
    • Buckler HM, McLachlan RI, MacLachlan VB, Healy DL, Burger HG (1988) Serum inhibin levels in polycystic ovary syndrome: basal levels and response to luteinizing hormone-releasing hormone agonist and exogenous gonadotropin administration. J Clin Endocrinol Metab 66:798–803
    • (1988) J Clin Endocrinol Metab , vol.66 , pp. 798-803
    • Buckler, H.M.1    McLachlan, R.I.2    MacLachlan, V.B.3    Healy, D.L.4    Burger, H.G.5
  • 12
    • 0023625387 scopus 로고
    • Use of LHRH agonists in the treatment of anovulation in women with polycystic ovary syndrome
    • COI: 1:STN:280:DyaL1c3pslGitQ%3D%3D, PID: 3136067
    • Franks S, Sagle M, Mason HD, Kiddy D (1987) Use of LHRH agonists in the treatment of anovulation in women with polycystic ovary syndrome. Horm Res 28:164–168
    • (1987) Horm Res , vol.28 , pp. 164-168
    • Franks, S.1    Sagle, M.2    Mason, H.D.3    Kiddy, D.4
  • 13
    • 0018906734 scopus 로고
    • Correlation of hyperandrogenism with hyperinsulinism in polycystic ovarian disease
    • COI: 1:STN:280:DyaL3c%2Fnt1eltA%3D%3D, PID: 7350174
    • Burghen GA, Givens JR, Kitabchi AE (1980) Correlation of hyperandrogenism with hyperinsulinism in polycystic ovarian disease. J Clin Endocrinol Metab 50:113–116
    • (1980) J Clin Endocrinol Metab , vol.50 , pp. 113-116
    • Burghen, G.A.1    Givens, J.R.2    Kitabchi, A.E.3
  • 14
    • 0041402647 scopus 로고    scopus 로고
    • Androgen excess is the key element in polycystic ovary syndrome
    • PID: 12909479
    • Azziz R (2003) Androgen excess is the key element in polycystic ovary syndrome. Fertil Steril 80:252–254
    • (2003) Fertil Steril , vol.80 , pp. 252-254
    • Azziz, R.1
  • 15
    • 34848839212 scopus 로고    scopus 로고
    • Role of insulin in the hyperandrogenemia of lean women with polycystic ovary syndrome and normal insulin sensitivity
    • COI: 1:CAS:528:DC%2BD2sXhtlSltLrO, PID: 17559844
    • Baillargeon JP, Carpentier A (2007) Role of insulin in the hyperandrogenemia of lean women with polycystic ovary syndrome and normal insulin sensitivity. Fertil Steril 88:886–893
    • (2007) Fertil Steril , vol.88 , pp. 886-893
    • Baillargeon, J.P.1    Carpentier, A.2
  • 16
  • 17
    • 30344440819 scopus 로고    scopus 로고
    • Reactive oxygen species-induced oxidative stress in the development of insulin resistance and hyperandrogenism in polycystic ovary syndrome
    • PID: 16249279
    • González F, Rote NS, Minium J, Kirwan JP (2006) Reactive oxygen species-induced oxidative stress in the development of insulin resistance and hyperandrogenism in polycystic ovary syndrome. J Clin Endocrinol Metab 91:336–340
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 336-340
    • González, F.1    Rote, N.S.2    Minium, J.3    Kirwan, J.P.4
  • 18
    • 0032937815 scopus 로고    scopus 로고
    • Effect of troglitazone on endocrine and ovulatory performance in women with insulin resistance-related polycystic ovary syndrome
    • COI: 1:STN:280:DyaK1M7ktV2gtw%3D%3D, PID: 9988406
    • Hasegawa I, Murakawa H, Suzuki M, Yamamoto Y, Kurabayashi T, Tanaka K (1999) Effect of troglitazone on endocrine and ovulatory performance in women with insulin resistance-related polycystic ovary syndrome. Fertil Steril 71:323–327
    • (1999) Fertil Steril , vol.71 , pp. 323-327
    • Hasegawa, I.1    Murakawa, H.2    Suzuki, M.3    Yamamoto, Y.4    Kurabayashi, T.5    Tanaka, K.6
  • 19
    • 0033614480 scopus 로고    scopus 로고
    • Ovulatory and metabolic effects of d-chiro-inositol in the polycystic ovary syndrome
    • COI: 1:CAS:528:DyaK1MXjtVWqt7c%3D, PID: 10219066
    • Nestler JE, Jakubowicz DJ, Reamer P, Gunn RD, Allan G (1999) Ovulatory and metabolic effects of d-chiro-inositol in the polycystic ovary syndrome. N Engl J Med 340:1314–1320
    • (1999) N Engl J Med , vol.340 , pp. 1314-1320
    • Nestler, J.E.1    Jakubowicz, D.J.2    Reamer, P.3    Gunn, R.D.4    Allan, G.5
  • 20
    • 2442639184 scopus 로고    scopus 로고
    • Effects of inositol on ovarian function and metabolic factors in women with PCOS: a randomized double blind placebo-controlled trial
    • COI: 1:STN:280:DC%2BD2czgsVWisw%3D%3D, PID: 15206484
    • Gerli S, Mignosa M, Di Renzo GC (2003) Effects of inositol on ovarian function and metabolic factors in women with PCOS: a randomized double blind placebo-controlled trial. Eur Rev Med Pharmacol Sci 7:151–159
    • (2003) Eur Rev Med Pharmacol Sci , vol.7 , pp. 151-159
    • Gerli, S.1    Mignosa, M.2    Di Renzo, G.C.3
  • 21
    • 0034886493 scopus 로고    scopus 로고
    • Effects of metformin on ovulation rate, hormonal and metabolic profiles in women with clomiphene-resistant polycystic ovaries: a randomized, double-blinded placebo-controlled trial
    • COI: 1:CAS:528:DC%2BD3MXmslWls7w%3D, PID: 11473953
    • Ng EH, Wat NM, Ho PC (2001) Effects of metformin on ovulation rate, hormonal and metabolic profiles in women with clomiphene-resistant polycystic ovaries: a randomized, double-blinded placebo-controlled trial. Hum Reprod 16:1625–1631
    • (2001) Hum Reprod , vol.16 , pp. 1625-1631
    • Ng, E.H.1    Wat, N.M.2    Ho, P.C.3
  • 23
    • 0028025883 scopus 로고
    • Multiple pathways in insulin signaling—fitting the covalent and allosteric puzzle pieces together
    • COI: 1:CAS:528:DyaK2cXkvF2qsb0%3D
    • Larner J (1994) Multiple pathways in insulin signaling—fitting the covalent and allosteric puzzle pieces together. Endocr J 2:167–171
    • (1994) Endocr J , vol.2 , pp. 167-171
    • Larner, J.1
  • 24
    • 84922185299 scopus 로고    scopus 로고
    • The rationale of the myo-inositol and d-chiro-inositol combined treatment for polycystic ovary syndrome
    • COI: 1:CAS:528:DC%2BC2cXhsFWjs73F, PID: 25042908
    • Dinicola S, Chiu TT, Unfer V, Carlomagno G, Bizzarri M (2014) The rationale of the myo-inositol and d-chiro-inositol combined treatment for polycystic ovary syndrome. J Clin Pharmacol 54:1079–1092
    • (2014) J Clin Pharmacol , vol.54 , pp. 1079-1092
    • Dinicola, S.1    Chiu, T.T.2    Unfer, V.3    Carlomagno, G.4    Bizzarri, M.5
  • 25
    • 0036401974 scopus 로고    scopus 로고
    • d-chiro-inositol–its functional role in insulin action and its deficit in insulin resistance
    • PID: 11900279
    • Larner J (2002) d-chiro-inositol–its functional role in insulin action and its deficit in insulin resistance. Int J Exp Diabetes Res 3:47–60
    • (2002) Int J Exp Diabetes Res , vol.3 , pp. 47-60
    • Larner, J.1
  • 26
    • 84906264515 scopus 로고    scopus 로고
    • Updates on the myo-inositol plus d-chiro-inositol combined therapy in polycystic ovary syndrome
    • COI: 1:CAS:528:DC%2BC2cXhtlequ7vJ, PID: 24898153
    • Unfer V, Porcaro G (2014) Updates on the myo-inositol plus d-chiro-inositol combined therapy in polycystic ovary syndrome. Expert Rev Clin Pharmacol 7:623–631
    • (2014) Expert Rev Clin Pharmacol , vol.7 , pp. 623-631
    • Unfer, V.1    Porcaro, G.2
  • 28
    • 84883203705 scopus 로고    scopus 로고
    • Endocrine and clinical effects of myo-inositol administration in polycystic ovary syndrome. A randomized study
    • COI: 1:CAS:528:DC%2BC3sXjvVeht7Y%3D, PID: 23336594
    • Artini PG, Di Berardino OM, Papini F, Genazzani AD, Simi G, Ruggiero M, Cela V (2013) Endocrine and clinical effects of myo-inositol administration in polycystic ovary syndrome. A randomized study. Gynecol Endocrinol 29:375–379
    • (2013) Gynecol Endocrinol , vol.29 , pp. 375-379
    • Artini, P.G.1    Di Berardino, O.M.2    Papini, F.3    Genazzani, A.D.4    Simi, G.5    Ruggiero, M.6    Cela, V.7
  • 29
    • 84864394223 scopus 로고    scopus 로고
    • Assessment of the modification of the clinical, endocrinal and metabolical profile of patients with PCOS syndrome treated with myo-inositol
    • COI: 1:STN:280:DC%2BC38fpt1Sqsw%3D%3D, PID: 22635019
    • Venturella R, Mocciaro R, De Trana E, D’Alessandro P, Morelli M, Zullo F (2012) Assessment of the modification of the clinical, endocrinal and metabolical profile of patients with PCOS syndrome treated with myo-inositol. Minerva Ginecol 64:239–243
    • (2012) Minerva Ginecol , vol.64 , pp. 239-243
    • Venturella, R.1    Mocciaro, R.2    De Trana, E.3    D’Alessandro, P.4    Morelli, M.5    Zullo, F.6
  • 31
    • 84857562131 scopus 로고    scopus 로고
    • Effects of myo-inositol in women with PCOS: a systematic review of randomized controlled trials
    • COI: 1:CAS:528:DC%2BC38XptlyltbY%3D, PID: 22296306
    • Unfer V, Carlomagno G, Dante G, Facchinetti F (2012) Effects of myo-inositol in women with PCOS: a systematic review of randomized controlled trials. Gynecol Endocrinol 28:509–515
    • (2012) Gynecol Endocrinol , vol.28 , pp. 509-515
    • Unfer, V.1    Carlomagno, G.2    Dante, G.3    Facchinetti, F.4
  • 32
    • 84891812104 scopus 로고    scopus 로고
    • Inositol: effects on oocyte quality in patients undergoing ICSI. An open study
    • COI: 1:STN:280:DC%2BC2c3jt1SktA%3D%3D, PID: 24302192
    • Brusco GF, Mariani M (2013) Inositol: effects on oocyte quality in patients undergoing ICSI. An open study. Eur Rev Med Pharmacol Sci 17:3095–3102
    • (2013) Eur Rev Med Pharmacol Sci , vol.17 , pp. 3095-3102
    • Brusco, G.F.1    Mariani, M.2
  • 33
    • 84925495938 scopus 로고    scopus 로고
    • Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance
    • Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD (2014) Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 26:1–5
    • (2014) Gynecol Endocrinol , vol.26 , pp. 1-5
    • Kamenov, Z.1    Kolarov, G.2    Gateva, A.3    Carlomagno, G.4    Genazzani, A.D.5
  • 34
    • 84889081839 scopus 로고    scopus 로고
    • The combined therapy myo-inositol plus d-chiro-inositol, rather than d-chiro-inositol, is able to improve IVF outcomes: results from a randomized controlled trial
    • COI: 1:CAS:528:DC%2BC3sXhslCls7jP, PID: 23708322
    • Colazingari S, Treglia M, Najjar R, Bevilacqua A (2013) The combined therapy myo-inositol plus d-chiro-inositol, rather than d-chiro-inositol, is able to improve IVF outcomes: results from a randomized controlled trial. Arch Gynecol Obstet 288:1405–1411
    • (2013) Arch Gynecol Obstet , vol.288 , pp. 1405-1411
    • Colazingari, S.1    Treglia, M.2    Najjar, R.3    Bevilacqua, A.4
  • 36
    • 84875424582 scopus 로고    scopus 로고
    • myo-Inositol supplementation and onset of gestational diabetes mellitus in pregnant women with a family history of type 2 diabetes: a prospective, randomized, placebo-controlled study
    • PID: 23340885
    • D’Anna R, Scilipoti A, Giordano D, Caruso C, Cannata ML, Interdonato ML, Corrado F, Di Benedetto A (2013) myo-Inositol supplementation and onset of gestational diabetes mellitus in pregnant women with a family history of type 2 diabetes: a prospective, randomized, placebo-controlled study. Diabetes Care 36:854–857
    • (2013) Diabetes Care , vol.36 , pp. 854-857
    • D’Anna, R.1    Scilipoti, A.2    Giordano, D.3    Caruso, C.4    Cannata, M.L.5    Interdonato, M.L.6    Corrado, F.7    Di Benedetto, A.8
  • 37
    • 84878944881 scopus 로고    scopus 로고
    • Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial
    • COI: 1:CAS:528:DC%2BC3sXptFCgtr0%3D, PID: 23327487
    • Matarrelli B, Vitacolonna E, D’Angelo M, Pavone G, Mattei PA, Liberati M, Celentano C (2013) Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 26:967–972
    • (2013) J Matern Fetal Neonatal Med , vol.26 , pp. 967-972
    • Matarrelli, B.1    Vitacolonna, E.2    D’Angelo, M.3    Pavone, G.4    Mattei, P.A.5    Liberati, M.6    Celentano, C.7
  • 39
    • 79960258634 scopus 로고    scopus 로고
    • The effect of myoinositol supplementation on insulin resistance in patients with gestational diabetes
    • COI: 1:CAS:528:DC%2BC3MXhtV2hs7%2FO, PID: 21414183
    • Corrado F, D’Anna R, Di Vieste G, Giordano D, Pintaudi B, Santamaria A, Di Benedetto A (2011) The effect of myoinositol supplementation on insulin resistance in patients with gestational diabetes. Diabet Med 28:972–975
    • (2011) Diabet Med , vol.28 , pp. 972-975
    • Corrado, F.1    D’Anna, R.2    Di Vieste, G.3    Giordano, D.4    Pintaudi, B.5    Santamaria, A.6    Di Benedetto, A.7
  • 40
    • 84894554207 scopus 로고    scopus 로고
    • Comparison between effects of myo-inositol and d-chiro-inositol on ovarian function and metabolic factors in women with PCOS
    • COI: 1:CAS:528:DC%2BC2cXjt1ams7g%3D, PID: 24351072
    • Pizzo A, Laganà AS, Barbaro L (2014) Comparison between effects of myo-inositol and d-chiro-inositol on ovarian function and metabolic factors in women with PCOS. Gynecol Endocrinol 30:205–208
    • (2014) Gynecol Endocrinol , vol.30 , pp. 205-208
    • Pizzo, A.1    Laganà, A.S.2    Barbaro, L.3
  • 41
    • 0037176512 scopus 로고    scopus 로고
    • Cohort studies: marching towards outcomes
    • PID: 11830217
    • Grimes DA, Schulz KF (2002) Cohort studies: marching towards outcomes. Lancet 359:341–345
    • (2002) Lancet , vol.359 , pp. 341-345
    • Grimes, D.A.1    Schulz, K.F.2
  • 42
    • 77952279621 scopus 로고    scopus 로고
    • CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials
    • PID: 20334632
    • Schulz KF, Altman DG, Moher D, CONSORT Group (2010) CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials. Trials 11:32
    • (2010) Trials , vol.11 , pp. 32
    • Schulz, K.F.1    Altman, D.G.2    Moher, D.3    CONSORT Group4
  • 45
    • 0019475222 scopus 로고
    • Medical implications of ultrasonically detected polycystic ovaries
    • COI: 1:STN:280:DyaL3M3hs1Sjtg%3D%3D, PID: 6787087
    • Swanson M, Sauerbrei EE, Cooperberg PL (1981) Medical implications of ultrasonically detected polycystic ovaries. J Clin Ultrasound 9:219–222
    • (1981) J Clin Ultrasound , vol.9 , pp. 219-222
    • Swanson, M.1    Sauerbrei, E.E.2    Cooperberg, P.L.3
  • 46
    • 84925498863 scopus 로고    scopus 로고
    • The menstrual cycle regularization following d-chiro-inositol treatment in PCOS women: a retrospective study
    • La Marca A, Grisendi V, Dondi G, Sighinolfi G, Cianci A (2014) The menstrual cycle regularization following d-chiro-inositol treatment in PCOS women: a retrospective study. Gynecol Endocrinol 30:1–5
    • (2014) Gynecol Endocrinol , vol.30 , pp. 1-5
    • La Marca, A.1    Grisendi, V.2    Dondi, G.3    Sighinolfi, G.4    Cianci, A.5
  • 47
    • 33749836234 scopus 로고    scopus 로고
    • Phosphoinositides in cell regulation and membrane dynamics
    • PID: 17035995
    • Di Paolo G, De Camilli P (2006) Phosphoinositides in cell regulation and membrane dynamics. Nature 443:651–657
    • (2006) Nature , vol.443 , pp. 651-657
    • Di Paolo, G.1    De Camilli, P.2
  • 48
    • 0014027508 scopus 로고
    • Biochemical studies on inositol. IX. d-Inositol 1-phosphate as intermediate in the biosynthesis of inositol from glucose 6-phosphate, and characteristics of two reactions in this biosynthesis
    • COI: 1:CAS:528:DyaF28XpsVynsQ%3D%3D, PID: 4287852
    • Chen IW, Charalampous CF (1966) Biochemical studies on inositol. IX. d-Inositol 1-phosphate as intermediate in the biosynthesis of inositol from glucose 6-phosphate, and characteristics of two reactions in this biosynthesis. J Biol Chem 241:2194–2199
    • (1966) J Biol Chem , vol.241 , pp. 2194-2199
    • Chen, I.W.1    Charalampous, C.F.2
  • 49
    • 84860902787 scopus 로고    scopus 로고
    • Does ovary need d-chiro-inositol?
    • COI: 1:CAS:528:DC%2BC3sXhtFanu7c%3D, PID: 22587479
    • Isabella R, Raffone E (2012) Does ovary need d-chiro-inositol? J Ovarian Res 5:14
    • (2012) J Ovarian Res , vol.5 , pp. 14
    • Isabella, R.1    Raffone, E.2
  • 50
    • 0027397521 scopus 로고
    • Chiroinositol deficiency and insulin resistance. III. Acute glycogenic and hypoglycemic effects of two inositol phosphoglycan insulin mediators in normal and streptozotocin-diabetic rats in vivo
    • COI: 1:CAS:528:DyaK3sXhtl2lsLg%3D, PID: 8425485
    • Huang LC, Fonteles MC, Houston DB, Zhang C, Larner J (1993) Chiroinositol deficiency and insulin resistance. III. Acute glycogenic and hypoglycemic effects of two inositol phosphoglycan insulin mediators in normal and streptozotocin-diabetic rats in vivo. Endocrinology 132:652–657
    • (1993) Endocrinology , vol.132 , pp. 652-657
    • Huang, L.C.1    Fonteles, M.C.2    Houston, D.B.3    Zhang, C.4    Larner, J.5
  • 51
    • 0027530657 scopus 로고
    • Chiroinositol deficiency and insulin resistance. I. Urinary excretion rate of chiroinositol is directly associated with insulin resistance in spontaneously diabetic rhesus monkeys
    • COI: 1:CAS:528:DyaK3sXhs1Kmsrc%3D, PID: 8425483
    • Ortmeyer HK, Bodkin NL, Lilley K, Larner J, Hansen BC (1993) Chiroinositol deficiency and insulin resistance. I. Urinary excretion rate of chiroinositol is directly associated with insulin resistance in spontaneously diabetic rhesus monkeys. Endocrinology 132:640–645
    • (1993) Endocrinology , vol.132 , pp. 640-645
    • Ortmeyer, H.K.1    Bodkin, N.L.2    Lilley, K.3    Larner, J.4    Hansen, B.C.5
  • 52
    • 0027253950 scopus 로고
    • Chiro-inositol deficiency and insulin resistance: a comparison of the chiro-inositol- and the myoinositol-containing insulin mediators isolated from urine, hemodialysate, and muscle of control and type II diabetic subjects
    • COI: 1:CAS:528:DyaK3sXltlKkt7w%3D, PID: 8392181
    • Asplin I, Galasko G, Larner J (1993) Chiro-inositol deficiency and insulin resistance: a comparison of the chiro-inositol- and the myoinositol-containing insulin mediators isolated from urine, hemodialysate, and muscle of control and type II diabetic subjects. Proc Natl Acad Sci USA 90:5924–5928
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5924-5928
    • Asplin, I.1    Galasko, G.2    Larner, J.3
  • 53
    • 0027530658 scopus 로고
    • Chiroinositol deficiency and insulin resistance. II. Acute effects of d-chiroinositol administration in streptozotocin-diabetic rats, normal rats given a glucose load, and spontaneously insulin resistant rhesus monkeys
    • COI: 1:CAS:528:DyaK3sXhtl2lsLs%3D, PID: 8425484
    • Ortmeyer HK, Huang LC, Zhang L, Hansen BC, Larner J (1993) Chiroinositol deficiency and insulin resistance. II. Acute effects of d-chiroinositol administration in streptozotocin-diabetic rats, normal rats given a glucose load, and spontaneously insulin resistant rhesus monkeys. Endocrinology 132:646–651
    • (1993) Endocrinology , vol.132 , pp. 646-651
    • Ortmeyer, H.K.1    Huang, L.C.2    Zhang, L.3    Hansen, B.C.4    Larner, J.5
  • 55
    • 0842312992 scopus 로고    scopus 로고
    • Metformin therapy increases insulin-stimulated release of d-chiro-inositol-containing inositolphosphoglycan mediator in women with polycystic ovary syndrome
    • COI: 1:CAS:528:DC%2BD2cXmvFCjtw%3D%3D, PID: 14715857
    • Baillargeon JP, Iuorno MJ, Jakubowicz DJ, Apridonidze T, He N, Nestler JE (2004) Metformin therapy increases insulin-stimulated release of d-chiro-inositol-containing inositolphosphoglycan mediator in women with polycystic ovary syndrome. J Clin Endocrinol Metab 89:242–249
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 242-249
    • Baillargeon, J.P.1    Iuorno, M.J.2    Jakubowicz, D.J.3    Apridonidze, T.4    He, N.5    Nestler, J.E.6


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