Development of a new DNA vaccine based on mycobacterial ESAT-6 antigen delivered by recombinant invasive Lactococcus lactis FnBPA+

Applied Microbiology and Biotechnology

Volumn 99, Issue 4, 2015, Pages 1817-1826

  Pereira, Vanessa Bastos ^a   Saraiva, Tessália Diniz Luerce ^a   Souza, Bianca Mendes ^a   Zurita Turk, Meritxell ^a   Azevedo, Marcela Santiago Pacheco ^a   De Castro, Camila Prósperi ^a   Mancha Agresti, Pamela ^a   dos Santos, Janete Soares Coelho ^b   Santos, Ana Cristina Gomes ^a   Faria, Ana Maria Caetano ^a   Leclercq, Sophie ^b   Azevedo, Vasco ^a   Miyoshi, Anderson ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b FUNDAÇÃO EZEQUIEL DIAS   (Brazil)

Author keywords

DNA delivery system; ESAT 6; Intestinal mucosa; Lactococcus lactis; Tuberculosis

Indexed keywords

ANTIGENS; BACTERIA; CLONING; DNA; DRUG THERAPY; GENES; LACTIC ACID; MAMMALS; RECOMBINANT PROTEINS;

DNA DELIVERY SYSTEM; ESAT-6; INTESTINAL MUCOSA; LACTOCOCCUS LACTIS; TUBERCULOSIS;

VACCINES;

BACTERIAL PROTEIN; BCG VACCINE; DNA VACCINE; EARLY SECRETORY ANTIGENIC TARGET 6; FIBRONECTIN BINDING PROTEIN; FIBRONECTIN BINDING PROTEIN A; GAMMA INTERFERON; SECRETORY IMMUNOGLOBULIN; UNCLASSIFIED DRUG; BACTERIAL ANTIGEN; DRUG CARRIER; ESAT-6 PROTEIN, MYCOBACTERIUM TUBERCULOSIS; RECOMBINANT VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIUM CARRIER; BCG VACCINATION; CELLULAR IMMUNITY; COLON; CONTROLLED STUDY; DNA IMMUNIZATION; EXPRESSION VECTOR; FECES; FEMALE; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOGLOBULIN PRODUCTION; INTERFERON PRODUCTION; LACTOCOCCUS LACTIS; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; SPLEEN CELL; TH1 CELL; TUBERCULOSIS; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; GENETICS; IMMUNOLOGY; ISOLATION AND PURIFICATION; MOLECULAR CLONING; MONONUCLEAR CELL; PLASMID; SECRETION (PROCESS); SPLEEN;

ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CLONING, MOLECULAR; COLON; DRUG CARRIERS; FECES; IMMUNOGLOBULIN A, SECRETORY; INTERFERON-GAMMA; LACTOCOCCUS LACTIS; LEUKOCYTES, MONONUCLEAR; MICE, INBRED BALB C; MYCOBACTERIUM TUBERCULOSIS; PLASMIDS; SPLEEN; TUBERCULOSIS VACCINES; VACCINES, DNA; VACCINES, SYNTHETIC;

EID: 84925521386     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-014-6285-3     Document Type: Article

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