Toward the establishment of standardized in vitro tests for lipid-based formulations. 5. lipolysis of representative formulations by gastric lipase

Pharmaceutical Research

Volumn 32, Issue 4, 2015, Pages 1279-1287

  Bakala N'Goma, Jean Claude ^a   Williams, Hywel D ^b   Sassene, Philip J ^c   Kleberg, Karen ^c   Calderone, Marilyn ^d   Jannin, Vincent ^e   Igonin, Annabel ^f   Partheil, Anette ^g   Marchaud, Delphine ^e   Jule, Eduardo ^f   Vertommen, Jan ^f   Maio, Mario ^h   Blundell, Ross ^d   Benameur, Hassan ^f   Müllertz, Anette ^c   Pouton, Colin W ^b   Porter, Christopher J H ^b   Carrière, Frédéric ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

^b MONASH UNIVERSITY   (Australia)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d SANOFI   (France)

^e GATTEFOSSÉ SAS   (France)

^f CAPSUGEL   (France)

^g MERCK KGAA   (Germany)

^h Zambon Pharma SpA   (Italy)

Author keywords

digestion; drug delivery; lipid formulation; lipolysis; stomach

Indexed keywords

CREMOPHOR; FATTY ACID; RECOMBINANT ENZYME; SURFACTANT; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; DRUG; PANCREATIN; RECOMBINANT PROTEIN;

ARTICLE; DIGESTION; DRUG FORMULATION; ENZYME ACTIVITY; ENZYME INHIBITION; IN VITRO STUDY; IONIZATION; LIPID BASED FORMULATION; LIPID METABOLISM; LIPOLYSIS; NONHUMAN; PH; PRIORITY JOURNAL; SMALL INTESTINE; STANDARDIZATION; TITRIMETRY; ANIMAL; CHEMISTRY; DOG; ENZYMOLOGY; HYDROLYSIS; MEDICINAL CHEMISTRY; METABOLISM; PROCEDURES; STANDARDS; STOMACH;

ANIMALS; CHEMISTRY, PHARMACEUTICAL; DIGESTION; DOGS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; LIPASE; LIPOLYSIS; PANCREATIN; PHARMACEUTICAL PREPARATIONS; RECOMBINANT PROTEINS; STOMACH; TRIGLYCERIDES;

EID: 84925488688     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-014-1532-y     Document Type: Article

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