메뉴 건너뛰기




Volumn 85, Issue 4, 2015, Pages 742-754

Spatiotemporal 16p11.2 Protein Network Implicates Cortical Late Mid-Fetal Brain Development and KCTD13-Cul3-RhoA Pathway in Psychiatric Diseases

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CULIN 3; KCTD10 PROTEIN; KCTD13 PROTEIN; NERVE GROWTH FACTOR RECEPTOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG; CUL3 PROTEIN, HUMAN; CULLIN; KCTD13 PROTEIN, HUMAN; NUCLEAR PROTEIN;

EID: 84925451823     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2015.01.010     Document Type: Article
Times cited : (120)

References (64)
  • 3
    • 57849117430 scopus 로고    scopus 로고
    • Rac1 deficiency in the forebrain results in neural progenitor reduction and microcephaly
    • Chen L., Melendez J., Campbell K., Kuan C.Y., Zheng Y. Rac1 deficiency in the forebrain results in neural progenitor reduction and microcephaly. Dev. Biol. 2009, 325:162-170.
    • (2009) Dev. Biol. , vol.325 , pp. 162-170
    • Chen, L.1    Melendez, J.2    Campbell, K.3    Kuan, C.Y.4    Zheng, Y.5
  • 4
    • 70349168448 scopus 로고    scopus 로고
    • Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement
    • Chen Y., Yang Z., Meng M., Zhao Y., Dong N., Yan H., Liu L., Ding M., Peng H.B., Shao F. Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement. Mol. Cell 2009, 35:841-855.
    • (2009) Mol. Cell , vol.35 , pp. 841-855
    • Chen, Y.1    Yang, Z.2    Meng, M.3    Zhao, Y.4    Dong, N.5    Yan, H.6    Liu, L.7    Ding, M.8    Peng, H.B.9    Shao, F.10
  • 5
    • 51649107017 scopus 로고    scopus 로고
    • Rare chromosomal deletions and duplications increase risk of schizophrenia
    • International Schizophrenia Consortium
    • Consortium I.S. Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature 2008, 455:237-241. International Schizophrenia Consortium.
    • (2008) Nature , vol.455 , pp. 237-241
    • Consortium, I.S.1
  • 8
    • 13244284551 scopus 로고    scopus 로고
    • Dynamic complex formation during the yeast cell cycle
    • de Lichtenberg U., Jensen L.J., Brunak S., Bork P. Dynamic complex formation during the yeast cell cycle. Science 2005, 307:724-727.
    • (2005) Science , vol.307 , pp. 724-727
    • de Lichtenberg, U.1    Jensen, L.J.2    Brunak, S.3    Bork, P.4
  • 10
    • 0035733690 scopus 로고    scopus 로고
    • Correlation between transcriptome and interactome mapping data from Saccharomyces cerevisiae
    • Ge H., Liu Z., Church G.M., Vidal M. Correlation between transcriptome and interactome mapping data from Saccharomyces cerevisiae. Nat. Genet. 2001, 29:482-486.
    • (2001) Nat. Genet. , vol.29 , pp. 482-486
    • Ge, H.1    Liu, Z.2    Church, G.M.3    Vidal, M.4
  • 11
    • 84883269669 scopus 로고    scopus 로고
    • The emerging family of CULLIN3-RING ubiquitin ligases (CRL3s): cellular functions and disease implications
    • Genschik P., Sumara I., Lechner E. The emerging family of CULLIN3-RING ubiquitin ligases (CRL3s): cellular functions and disease implications. EMBO J. 2013, 32:2307-2320.
    • (2013) EMBO J. , vol.32 , pp. 2307-2320
    • Genschik, P.1    Sumara, I.2    Lechner, E.3
  • 12
    • 79958035893 scopus 로고    scopus 로고
    • Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses
    • Gilman S.R., Iossifov I., Levy D., Ronemus M., Wigler M., Vitkup D. Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses. Neuron 2011, 70:898-907.
    • (2011) Neuron , vol.70 , pp. 898-907
    • Gilman, S.R.1    Iossifov, I.2    Levy, D.3    Ronemus, M.4    Wigler, M.5    Vitkup, D.6
  • 15
    • 79955735275 scopus 로고    scopus 로고
    • The role of Rho GTPase proteins in CNS neuronal migration
    • Govek E.E., Hatten M.E., Van Aelst L. The role of Rho GTPase proteins in CNS neuronal migration. Dev. Neurobiol. 2011, 71:528-553.
    • (2011) Dev. Neurobiol. , vol.71 , pp. 528-553
    • Govek, E.E.1    Hatten, M.E.2    Van Aelst, L.3
  • 16
    • 0035445792 scopus 로고    scopus 로고
    • A relationship between gene expression and protein interactions on the proteome scale: analysis of the bacteriophage T7 and the yeast Saccharomyces cerevisiae
    • Grigoriev A. A relationship between gene expression and protein interactions on the proteome scale: analysis of the bacteriophage T7 and the yeast Saccharomyces cerevisiae. Nucleic Acids Res. 2001, 29:3513-3519.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 3513-3519
    • Grigoriev, A.1
  • 17
    • 84881193129 scopus 로고    scopus 로고
    • Spatial and temporal mapping of de novo mutations in schizophrenia to a fetal prefrontal cortical network
    • Consortium on the Genetics of Schizophrenia (COGS), PAARTNERS Study GroupPAARTNERS Study Group
    • Gulsuner S., Walsh T., Watts A.C., Lee M.K., Thornton A.M., Casadei S., Rippey C., Shahin H., Nimgaonkar V.L., Go R.C., et al. Spatial and temporal mapping of de novo mutations in schizophrenia to a fetal prefrontal cortical network. Cell 2013, 154:518-529. Consortium on the Genetics of Schizophrenia (COGS), PAARTNERS Study GroupPAARTNERS Study Group.
    • (2013) Cell , vol.154 , pp. 518-529
    • Gulsuner, S.1    Walsh, T.2    Watts, A.C.3    Lee, M.K.4    Thornton, A.M.5    Casadei, S.6    Rippey, C.7    Shahin, H.8    Nimgaonkar, V.L.9    Go, R.C.10
  • 19
    • 0035834008 scopus 로고    scopus 로고
    • A tumor necrosis factor alpha- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase delta and proliferating cell nuclear antigen
    • He H., Tan C.K., Downey K.M., So A.G. A tumor necrosis factor alpha- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase delta and proliferating cell nuclear antigen. Proc. Natl. Acad. Sci. USA 2001, 98:11979-11984.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 11979-11984
    • He, H.1    Tan, C.K.2    Downey, K.M.3    So, A.G.4
  • 22
    • 0036141992 scopus 로고    scopus 로고
    • Relating whole-genome expression data with protein-protein interactions
    • Jansen R., Greenbaum D., Gerstein M. Relating whole-genome expression data with protein-protein interactions. Genome Res. 2002, 12:37-46.
    • (2002) Genome Res. , vol.12 , pp. 37-46
    • Jansen, R.1    Greenbaum, D.2    Gerstein, M.3
  • 24
    • 64549147485 scopus 로고    scopus 로고
    • Support for the involvement of large copy number variants in the pathogenesis of schizophrenia
    • International Schizophrenia Consortium, Wellcome Trust Case Control ConsortiumWellcome Trust Case Control Consortium
    • Kirov G., Grozeva D., Norton N., Ivanov D., Mantripragada K.K., Holmans P., Craddock N., Owen M.J., O'Donovan M.C. Support for the involvement of large copy number variants in the pathogenesis of schizophrenia. Hum. Mol. Genet. 2009, 18:1497-1503. International Schizophrenia Consortium, Wellcome Trust Case Control ConsortiumWellcome Trust Case Control Consortium.
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 1497-1503
    • Kirov, G.1    Grozeva, D.2    Norton, N.3    Ivanov, D.4    Mantripragada, K.K.5    Holmans, P.6    Craddock, N.7    Owen, M.J.8    O'Donovan, M.C.9
  • 25
    • 84908529852 scopus 로고    scopus 로고
    • Decoding neuroproteomics: integrating the genome, translatome and functional anatomy
    • Kitchen R.R., Rozowsky J.S., Gerstein M.B., Nairn A.C. Decoding neuroproteomics: integrating the genome, translatome and functional anatomy. Nat. Neurosci. 2014, 17:1491-1499.
    • (2014) Nat. Neurosci. , vol.17 , pp. 1491-1499
    • Kitchen, R.R.1    Rozowsky, J.S.2    Gerstein, M.B.3    Nairn, A.C.4
  • 30
    • 84863988574 scopus 로고    scopus 로고
    • Genome-wide transcriptome profiling reveals the functional impact of rare de novo and recurrent CNVs in autism spectrum disorders
    • Luo R., Sanders S.J., Tian Y., Voineagu I., Huang N., Chu S.H., Klei L., Cai C., Ou J., Lowe J.K., et al. Genome-wide transcriptome profiling reveals the functional impact of rare de novo and recurrent CNVs in autism spectrum disorders. Am. J. Hum. Genet. 2012, 91:38-55.
    • (2012) Am. J. Hum. Genet. , vol.91 , pp. 38-55
    • Luo, R.1    Sanders, S.J.2    Tian, Y.3    Voineagu, I.4    Huang, N.5    Chu, S.H.6    Klei, L.7    Cai, C.8    Ou, J.9    Lowe, J.K.10
  • 31
    • 4644326931 scopus 로고    scopus 로고
    • Genomic analysis of regulatory network dynamics reveals large topological changes
    • Luscombe N.M., Babu M.M., Yu H., Snyder M., Teichmann S.A., Gerstein M. Genomic analysis of regulatory network dynamics reveals large topological changes. Nature 2004, 431:308-312.
    • (2004) Nature , vol.431 , pp. 308-312
    • Luscombe, N.M.1    Babu, M.M.2    Yu, H.3    Snyder, M.4    Teichmann, S.A.5    Gerstein, M.6
  • 32
    • 84858434210 scopus 로고    scopus 로고
    • CNVs: harbingers of a rare variant revolution in psychiatric genetics
    • Malhotra D., Sebat J. CNVs: harbingers of a rare variant revolution in psychiatric genetics. Cell 2012, 148:1223-1241.
    • (2012) Cell , vol.148 , pp. 1223-1241
    • Malhotra, D.1    Sebat, J.2
  • 36
    • 70449724778 scopus 로고    scopus 로고
    • Copy-number variants in neurodevelopmental disorders: promises and challenges
    • Merikangas A.K., Corvin A.P., Gallagher L. Copy-number variants in neurodevelopmental disorders: promises and challenges. Trends Genet. 2009, 25:536-544.
    • (2009) Trends Genet. , vol.25 , pp. 536-544
    • Merikangas, A.K.1    Corvin, A.P.2    Gallagher, L.3
  • 40
    • 84893798071 scopus 로고    scopus 로고
    • Reciprocal duplication of the Williams-Beuren syndrome deletion on chromosome 7q11.23 is associated with schizophrenia
    • Molecular Genetics of Schizophrenia Consortium
    • Mulle J.G., Pulver A.E., McGrath J.A., Wolyniec P.S., Dodd A.F., Cutler D.J., Sebat J., Malhotra D., Nestadt G., Conrad D.F., et al. Reciprocal duplication of the Williams-Beuren syndrome deletion on chromosome 7q11.23 is associated with schizophrenia. Biol. Psychiatry 2014, 75:371-377. Molecular Genetics of Schizophrenia Consortium.
    • (2014) Biol. Psychiatry , vol.75 , pp. 371-377
    • Mulle, J.G.1    Pulver, A.E.2    McGrath, J.A.3    Wolyniec, P.S.4    Dodd, A.F.5    Cutler, D.J.6    Sebat, J.7    Malhotra, D.8    Nestadt, G.9    Conrad, D.F.10
  • 43
    • 84889561601 scopus 로고    scopus 로고
    • Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism
    • Parikshak N.N., Luo R., Zhang A., Won H., Lowe J.K., Chandran V., Horvath S., Geschwind D.H. Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism. Cell 2013, 155:1008-1021.
    • (2013) Cell , vol.155 , pp. 1008-1021
    • Parikshak, N.N.1    Luo, R.2    Zhang, A.3    Won, H.4    Lowe, J.K.5    Chandran, V.6    Horvath, S.7    Geschwind, D.H.8
  • 50
    • 0842309161 scopus 로고    scopus 로고
    • Discovering molecular pathways from protein interaction and gene expression data
    • Segal E., Wang H., Koller D. Discovering molecular pathways from protein interaction and gene expression data. Bioinformatics 2003, 19(Suppl 1):i264-i271.
    • (2003) Bioinformatics , vol.19 , pp. i264-i271
    • Segal, E.1    Wang, H.2    Koller, D.3
  • 51
    • 84882455458 scopus 로고    scopus 로고
    • Single-cell sequencing-based technologies will revolutionize whole-organism science
    • Shapiro E., Biezuner T., Linnarsson S. Single-cell sequencing-based technologies will revolutionize whole-organism science. Nat. Rev. Genet. 2013, 14:618-630.
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 618-630
    • Shapiro, E.1    Biezuner, T.2    Linnarsson, S.3
  • 55
    • 84867247848 scopus 로고    scopus 로고
    • Intra-axonal translation of RhoA promotes axon growth inhibition by CSPG
    • Walker B.A., Ji S.J., Jaffrey S.R. Intra-axonal translation of RhoA promotes axon growth inhibition by CSPG. J.Neurosci. 2012, 32:14442-14447.
    • (2012) J.Neurosci. , vol.32 , pp. 14442-14447
    • Walker, B.A.1    Ji, S.J.2    Jaffrey, S.R.3
  • 57
    • 62649102889 scopus 로고    scopus 로고
    • KCTD10 interacts with proliferating cell nuclear antigen and its down-regulation could inhibit cell proliferation
    • Wang Y., Zheng Y., Luo F., Fan X., Chen J., Zhang C., Hui R. KCTD10 interacts with proliferating cell nuclear antigen and its down-regulation could inhibit cell proliferation. J.Cell. Biochem. 2009, 106:409-413.
    • (2009) J.Cell. Biochem. , vol.106 , pp. 409-413
    • Wang, Y.1    Zheng, Y.2    Luo, F.3    Fan, X.4    Chen, J.5    Zhang, C.6    Hui, R.7
  • 62
    • 38849119148 scopus 로고    scopus 로고
    • The PAR-6 polarity protein regulates dendritic spine morphogenesis through p190 RhoGAP and the Rho GTPase
    • Zhang H., Macara I.G. The PAR-6 polarity protein regulates dendritic spine morphogenesis through p190 RhoGAP and the Rho GTPase. Dev. Cell 2008, 14:216-226.
    • (2008) Dev. Cell , vol.14 , pp. 216-226
    • Zhang, H.1    Macara, I.G.2
  • 64
    • 40449087736 scopus 로고    scopus 로고
    • RhoA prevents apoptosis during zebrafish embryogenesis through activation of Mek/Erk pathway
    • Zhu S., Korzh V., Gong Z., Low B.C. RhoA prevents apoptosis during zebrafish embryogenesis through activation of Mek/Erk pathway. Oncogene 2008, 27:1580-1589.
    • (2008) Oncogene , vol.27 , pp. 1580-1589
    • Zhu, S.1    Korzh, V.2    Gong, Z.3    Low, B.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.