메뉴 건너뛰기




Volumn 6, Issue 3, 2014, Pages 205-212

An in vivo and in vitro investigation of the effect of Aloe vera gel ethanolic extract using animal model with diabetic foot ulcer

Author keywords

Aloe vera; Ayurveda; ethanolic extract; hypoglycemia; streptozotocin

Indexed keywords

ALOE VERA EXTRACT; GLUCOSE; GLYCOSAMINOGLYCAN; INSULIN;

EID: 84925446783     PISSN: None     EISSN: 09757406     Source Type: Journal    
DOI: 10.4103/0975-7406.135248     Document Type: Article
Times cited : (34)

References (42)
  • 1
  • 2
    • 0031883730 scopus 로고    scopus 로고
    • Influence of Aloe vera on collagen characteristics in healing dermal wounds in rats
    • Chithra P, Sajithlal GB, Chandrakasan G. Influence of Aloe vera on collagen characteristics in healing dermal wounds in rats. Mol Cell Biochem 1998;181:71-6.
    • (1998) Mol Cell Biochem , vol.181 , pp. 71-76
    • Chithra, P.1    Sajithlal, G.B.2    Chandrakasan, G.3
  • 3
    • 0031975533 scopus 로고    scopus 로고
    • Influence of Aloe vera on the glycosaminoglycans in the matrix of healing dermal wounds in rats
    • Chithra P, Sajithlal GB, Chandrakasan G. Influence of Aloe vera on the glycosaminoglycans in the matrix of healing dermal wounds in rats. J Ethnopharmacol 1998;59:179-86.
    • (1998) J Ethnopharmacol , vol.59 , pp. 179-186
    • Chithra, P.1    Sajithlal, G.B.2    Chandrakasan, G.3
  • 4
    • 0036910412 scopus 로고    scopus 로고
    • Wound pathophysiology, infection and therapeutic options
    • Bowler PG. Wound pathophysiology, infection and therapeutic options. Ann Med 2002;34:419-27.
    • (2002) Ann Med , vol.34 , pp. 419-427
    • Bowler, P.G.1
  • 5
    • 34248225758 scopus 로고    scopus 로고
    • Cellular and molecular basis of wound healing in diabetes
    • Brem H, Tomic-Canic M. Cellular and molecular basis of wound healing in diabetes. J Clin Invest 2007;117:1219-22.
    • (2007) J Clin Invest , vol.117 , pp. 1219-1222
    • Brem, H.1    Tomic-Canic, M.2
  • 6
    • 1842423773 scopus 로고    scopus 로고
    • Hypoglycemic effect of Aloe vera gel on streptozotocin-induced diabetes in experimental rats
    • Rajasekaran S, Sivagnanam K, Ravi K, Subramanian S. Hypoglycemic effect of Aloe vera gel on streptozotocin-induced diabetes in experimental rats. J Med Food 2004;7:61-6.
    • (2004) J Med Food , vol.7 , pp. 61-66
    • Rajasekaran, S.1    Sivagnanam, K.2    Ravi, K.3    Subramanian, S.4
  • 7
    • 18044363640 scopus 로고    scopus 로고
    • Antioxidant effect of Aloe vera gel extract in streptozotocin-induced diabetic in experimental rats
    • Rajasekaran S, Sivagnanam K, Subramanian S. Antioxidant effect of Aloe vera gel extract in streptozotocin-induced diabetic in experimental rats. Pharmacol Rep 2005;57:90-6.
    • (2005) Pharmacol Rep , vol.57 , pp. 90-96
    • Rajasekaran, S.1    Sivagnanam, K.2    Subramanian, S.3
  • 9
    • 79952860374 scopus 로고    scopus 로고
    • Inhibition of aldehyde dehydrogenase 2 by oxidative stress is associated with cardiac dysfunction in diabetic rats
    • Wang J, Wang H, Hao P, Xue L, Wei S, Zhang Y, et al. Inhibition of aldehyde dehydrogenase 2 by oxidative stress is associated with cardiac dysfunction in diabetic rats. Mol Med 2011;17:172-9.
    • (2011) Mol Med , vol.17 , pp. 172-179
    • Wang, J.1    Wang, H.2    Hao, P.3    Xue, L.4    Wei, S.5    Zhang, Y.6
  • 10
    • 46749089039 scopus 로고    scopus 로고
    • An in vivo investigation of the wound-healing effect of two medicinal herbs using an animal model with foot
    • Lau TW, Sahota DS, Lau CH, Chan CM, Lam FC, Ho YY, et al. An in vivo investigation of the wound-healing effect of two medicinal herbs using an animal model with foot. Eur Surg Res 2008;41:15-23.
    • (2008) Eur Surg Res , vol.41 , pp. 15-23
    • Lau, T.W.1    Sahota, D.S.2    Lau, C.H.3    Chan, C.M.4    Lam, F.C.5    Ho, Y.Y.6
  • 11
    • 3342971369 scopus 로고    scopus 로고
    • The DEPA scoring system and its correlation with the healing rate of diabetic foot ulcers
    • Younes NA, Albsoul AM. The DEPA scoring system and its correlation with the healing rate of diabetic foot ulcers. J Foot Ankle Surg 2004;43:209-13.
    • (2004) J Foot Ankle Surg , vol.43 , pp. 209-213
    • Younes, N.A.1    Albsoul, A.M.2
  • 12
    • 0034662444 scopus 로고    scopus 로고
    • Evaluation of in-vivo wound healing activity of Hypericum patulum (Family: Hypericaceae) leaf extract on different wound model in rats
    • Mukherjee PK, Verpoorte R, Suresh B. Evaluation of in-vivo wound healing activity of Hypericum patulum (Family: Hypericaceae) leaf extract on different wound model in rats. J Ethnopharmacol 2000;70:315-21.
    • (2000) J Ethnopharmacol , vol.70 , pp. 315-321
    • Mukherjee, P.K.1    Verpoorte, R.2    Suresh, B.3
  • 13
    • 0018895979 scopus 로고
    • Quantitative microanalysis of synovial fluid and articular cartilage glycosaminoglycans
    • Smith RL, Gilkerson E, Kohatsu N, Merchant T, Schurman DJ. Quantitative microanalysis of synovial fluid and articular cartilage glycosaminoglycans. Anal Biochem 1980;103:191-200.
    • (1980) Anal Biochem , vol.103 , pp. 191-200
    • Smith, R.L.1    Gilkerson, E.2    Kohatsu, N.3    Merchant, T.4    Schurman, D.J.5
  • 14
    • 6544229829 scopus 로고
    • A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid
    • Burton K. A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem J 1956;62:315-23.
    • (1956) Biochem J , vol.62 , pp. 315-323
    • Burton, K.1
  • 15
    • 77049235240 scopus 로고
    • The relation between the synthesis of deoxyribonucleic acid and the synthesis of protein in the multiplication of bacteriophage T2
    • Burton K. The relation between the synthesis of deoxyribonucleic acid and the synthesis of protein in the multiplication of bacteriophage T2. Biochem J 1955;61:473-83.
    • (1955) Biochem J , vol.61 , pp. 473-483
    • Burton, K.1
  • 16
    • 0025234740 scopus 로고
    • Effect of Aloes on blood glucose levels in normal and alloxan diabetic mice
    • Ajabnoor MA. Effect of Aloes on blood glucose levels in normal and alloxan diabetic mice. J Ethnopharmacol 1990;28:215-20.
    • (1990) J Ethnopharmacol , vol.28 , pp. 215-220
    • Ajabnoor, M.A.1
  • 17
    • 67650568107 scopus 로고    scopus 로고
    • Hypoglycemic and hypolipidemic effects of processed A vera gel in a mouse model of non-insulin-dependent diabetes mellitus
    • Kim K, Kim H, Kwon J, Lee S, Kong H, Im SA, et al. Hypoglycemic and hypolipidemic effects of processed A. vera gel in a mouse model of non-insulin-dependent diabetes mellitus. Phytomedicine 2009;16:856-63.
    • (2009) Phytomedicine , vol.16 , pp. 856-863
    • Kim, K.1    Kim, H.2    Kwon, J.3    Lee, S.4    Kong, H.5    Im, S.A.6
  • 18
    • 33646806070 scopus 로고    scopus 로고
    • An evaluation of the biological and toxicological properties of A barbadensis (Miller), A vera
    • Boudreau MD, Beland FA. An Evaluation of the biological and toxicological properties of A. barbadensis (Miller), A. vera. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 2006;24:103-54.
    • (2006) J Environ Sci Health C Environ Carcinog Ecotoxicol Rev , vol.24 , pp. 103-154
    • Boudreau, M.D.1    Beland, F.A.2
  • 19
    • 0027077867 scopus 로고
    • Glucose and glucose analogs modulate collagen metabolism
    • Lien YH, Tseng MM, Stern R. Glucose and glucose analogs modulate collagen metabolism. Exp Mol Pathol 1992;57:215-21.
    • (1992) Exp Mol Pathol , vol.57 , pp. 215-221
    • Lien, Y.H.1    Tseng, M.M.2    Stern, R.3
  • 21
    • 84961015525 scopus 로고
    • Chemical and histochemical sequences in the normal healing wounds
    • Dunphy JE, Udupa KN. Chemical and histochemical sequences in the normal healing wounds. N Engl J Med 1955;253:847-51.
    • (1955) N Engl J Med , vol.253 , pp. 847-851
    • Dunphy, J.E.1    Udupa, K.N.2
  • 22
    • 0033797433 scopus 로고    scopus 로고
    • The wound healing properties of Channa striatus-cetrimide cream-wound contraction and glycosaminoglycan measurement
    • Baie SH, Sheikh KA. The wound healing properties of Channa striatus-cetrimide cream-wound contraction and glycosaminoglycan measurement. J Ethnopharmacol 2000;73:15-30.
    • (2000) J Ethnopharmacol , vol.73 , pp. 15-30
    • Baie, S.H.1    Sheikh, K.A.2
  • 24
    • 0032744713 scopus 로고    scopus 로고
    • Aloe vera leaf gel: A review update
    • Reynolds T, Dweck AC. Aloe vera leaf gel: A review update. J Ethnopharmacol 1999;68:3-37.
    • (1999) J Ethnopharmacol , vol.68 , pp. 3-37
    • Reynolds, T.1    Dweck, A.C.2
  • 25
    • 0022383559 scopus 로고
    • Thromboxane inhibitors for the prevention of progressive dermal ischemia due to the thermal injury
    • Heggers JP, Robson MC, Zachary LS. Thromboxane inhibitors for the prevention of progressive dermal ischemia due to the thermal injury. J Burn Care Rehabil 1985;6:466-8.
    • (1985) J Burn Care Rehabil , vol.6 , pp. 466-468
    • Heggers, J.P.1    Robson, M.C.2    Zachary, L.S.3
  • 26
    • 0029016614 scopus 로고
    • Treatment of experimental frostbite with pentoxifylline and A1 vera cream
    • Miller MB, Koltai PJ. Treatment of experimental frostbite with pentoxifylline and A. vera cream. Arch Otolaryngol Head Neck Surg 1995;121:678-80.
    • (1995) Arch Otolaryngol Head Neck Surg , vol.121 , pp. 678-680
    • Miller, M.B.1    Koltai, P.J.2
  • 28
    • 0023954103 scopus 로고
    • Aloe vera. A natural approach for treating wounds, edema, and pain in diabetes
    • Davis RH, Leitner MG, Russo JM. Aloe vera. A natural approach for treating wounds, edema, and pain in diabetes. J Am Podiatr Med Assoc 1988;78:60-8.
    • (1988) J Am Podiatr Med Assoc , vol.78 , pp. 60-68
    • Davis, R.H.1    Leitner, M.G.2    Russo, J.M.3
  • 29
    • 0025038171 scopus 로고
    • Stimulation of collagen synthesis in fibroblast cultures by a triterpene extracted from Centella asiatica
    • Maquart FX, Bellon G, Gillery P, Wegrowski Y, Borel JP. Stimulation of collagen synthesis in fibroblast cultures by a triterpene extracted from Centella asiatica. Connect Tissue Res 1990;24:107-20.
    • (1990) Connect Tissue Res , vol.24 , pp. 107-120
    • Maquart, F.X.1    Bellon, G.2    Gillery, P.3    Wegrowski, Y.4    Borel, J.P.5
  • 30
    • 0029799760 scopus 로고    scopus 로고
    • Effects of Centella asiatica extract on dermal wound healing in rats
    • Suguna L, Sivakumar P, Chandrakasan G. Effects of Centella asiatica extract on dermal wound healing in rats. Indian J Exp Biol 1996;34:1208-11.
    • (1996) Indian J Exp Biol , vol.34 , pp. 1208-1211
    • Suguna, L.1    Sivakumar, P.2    Chandrakasan, G.3
  • 31
    • 0028835878 scopus 로고
    • Antidiabetic plants and their active constituents
    • Marles JR, Farnsworth NR. Antidiabetic plants and their active constituents. Phytomedicine 1995;2:123-89.
    • (1995) Phytomedicine , vol.2 , pp. 123-189
    • Marles, J.R.1    Farnsworth, N.R.2
  • 32
    • 84865076949 scopus 로고    scopus 로고
    • A systematic review of in vitro studies conducted on effect of herbal products on secretion of insulin from langerhans islets
    • Tabatabaei-Malazy O, Larijani B, Abdollahi M. A systematic review of in vitro studies conducted on effect of herbal products on secretion of insulin from langerhans islets. J Pharm Pharmaceut Sci 2012;15:447-66.
    • (2012) J Pharm Pharmaceut Sci , vol.15 , pp. 447-466
    • Tabatabaei-Malazy, O.1    Larijani, B.2    Abdollahi, M.3
  • 33
    • 1942424088 scopus 로고    scopus 로고
    • Natural Medicines used in traditional Chinese medicine system for therapy of diabetes mellitus
    • Li WL, Zheng HC, Bukru J, Dekimpe N. Natural Medicines used in traditional Chinese medicine system for therapy of diabetes mellitus. J Ethnopharmacol 2004;92:1-21.
    • (2004) J Ethnopharmacol , vol.92 , pp. 1-21
    • Li, W.L.1    Zheng, H.C.2    Bukru, J.3    Dekimpe, N.4
  • 34
    • 79955971369 scopus 로고    scopus 로고
    • Toxicological and hypoglycemic studies on the leaves of Cissampelos Mucronata (Menispermaceae) on blood glucose levels of streptozocin-induced diabetic wistar rats
    • Tanko Y, Yaro AH, Isa AI, Erima M, Saleh MI, Mohammed A. Toxicological and hypoglycemic studies on the leaves of Cissampelos Mucronata (Menispermaceae) on blood glucose levels of streptozocin-induced diabetic wistar rats. J Med Plants Res 2007;1:113-6.
    • (2007) J Med Plants Res , vol.1 , pp. 113-116
    • Tanko, Y.1    Yaro, A.H.2    Isa, A.I.3    Erima, M.4    Saleh, M.I.5    Mohammed, A.6
  • 35
    • 0029800729 scopus 로고    scopus 로고
    • Toxicological evaluation of fenugreek seeds: A long term feeding experiment in diabetic patients
    • Sherma RD, Sarkhar DK, Hazra MB. Toxicological evaluation of fenugreek seeds: A long term feeding experiment in diabetic patients. Phytother Res 2010;10:519-20.
    • (2010) Phytother Res , vol.10 , pp. 519-520
    • Sherma, R.D.1    Sarkhar, D.K.2    Hazra, M.B.3
  • 36
    • 80052776971 scopus 로고    scopus 로고
    • Antidiabetic activity of Crateva nurvala stem bark extracts in alloxan-induced diabetic rats
    • Sikarwar MS, Patil MB. Antidiabetic activity of Crateva nurvala stem bark extracts in alloxan-induced diabetic rats. J Pharm Bioallied Sci 2010;2:18-21.
    • (2010) J Pharm Bioallied Sci , vol.2 , pp. 18-21
    • Sikarwar, M.S.1    Patil, M.B.2
  • 37
    • 84861369320 scopus 로고    scopus 로고
    • Plants and natural compounds with antidiabetic action
    • Coman C, Rugina OD, Socaciu C. Plants and natural compounds with antidiabetic action. Not Bot Horti Agrobo 2012;40:314-25.
    • (2012) Not Bot Horti Agrobo , vol.40 , pp. 314-325
    • Coman, C.1    Rugina, O.D.2    Socaciu, C.3
  • 39
    • 77951229157 scopus 로고    scopus 로고
    • Antihyperglicemic antihyperlipidemic and antioxidant effects and the probable mechanisms of action of Ruta graveolens infusion and rutin in nicotinamide-streptozotocin-induced diabetic rats
    • Ahmed OM, Moneim AA, Yazid IA, Mahmoud AM. Antihyperglicemic antihyperlipidemic and antioxidant effects and the probable mechanisms of action of Ruta graveolens infusion and rutin in nicotinamide-streptozotocin-induced diabetic rats. Diabetologia Croatica 2010;39:15-35.
    • (2010) Diabetologia Croatica , vol.39 , pp. 15-35
    • Ahmed, O.M.1    Moneim, A.A.2    Yazid, I.A.3    Mahmoud, A.M.4
  • 40
    • 0014241763 scopus 로고
    • Acceleration of primay wound healing by insulin
    • Rosenthal SP. Acceleration of primay wound healing by insulin. Arch Surg 1968;96:53-5.
    • (1968) Arch Surg , vol.96 , pp. 53-55
    • Rosenthal, S.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.