Influence of Aloe vera on the glycosaminoglycans in the matrix of healing dermal wounds in rats

Journal of Ethnopharmacology

Volumn 59, Issue 3, 1998, Pages 179-186

  Chithra, P ^a   Sajithlal, G B ^a   Chandrakasan, Gowri ^a  

^a CENTRAL LEATHER RESEARCH INSTITUTE   (India)

Author keywords

Aloe vera; Glycohydrolases; Glycosaminoglycans; Wound healing

Indexed keywords

ACETYLGLUCOSAMINIDASE; ALOE VERA EXTRACT; BETA GALACTOSIDASE; BETA GLUCOSIDASE; BETA GLUCURONIDASE; COLLAGEN; DERMATAN SULFATE; ELASTIN; GLYCOSAMINOGLYCAN; GLYCOSIDASE; HYALURONIC ACID; PROTEOGLYCAN; URONIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GRANULATION TISSUE; MALE; METABOLISM; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; SKIN INJURY; TOPICAL DRUG ADMINISTRATION; WOUND HEALING;

ACETYLGLUCOSAMINIDASE; ALOE; ANIMALS; EXTRACELLULAR MATRIX; GLUCURONIDASE; GLYCOSAMINOGLYCANS; MALE; PLANT EXTRACTS; PLANTS, MEDICINAL; RATS; RATS, WISTAR; SKIN; WOUND HEALING;

EID: 0031975533     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-8741(97)00112-8     Document Type: Article

References (33)

1. Alison, M.R., 1992. The response to injury: Repair and regenerative responses. In: McGee, J.O'D., Isaacson, P.G., Wright, N.A. (Eds.), Oxford Textbook of Pathology, Vol. 1. Principles of Pathology. Oxford University Press, London.
2. Bitter T., Muir H.M. A modified uronic acid carbazole reaction. Analytical Biochemistry. 4:1962;330-334.
3. Breen M., Knepper P.A., Weinstein H.G., Blacik L.J., Lewandowski D.G., Baltrus B.M. Microanalysis of glycosaminoglycans. Analytical Biochemistry. 113:1981;416-422.
4. Conchie J., Gelman A. L, Levvy G.A. Inhibition of glycosidases by aldonolactones of corresponding configuration. The C-4 and C-6 specificity of β-glucosidase, β-galactosidase. Biochemical Journal. 103:1967;609-615.
5. d'Ardenne, A.J., 1992. Ground substance. In: McGee, J.O'D., Isaacson, P.G., Wright, N.A. (Eds.), Oxford Textbook of Pathology, Vol. 1. Principles of Pathology. Oxford University Press, London.
6. Davis R.H., Donato J.J.D., Hartman G.M., Haas R.C. Anti-inflammatory and wound healing activity of a growth substance in Aloe vera. Journal of the American Podiatric Medical Association. 84:1994;77-81.
7. De Palma R.L., Krummel T.M., Durham L.A., Michna B.A., Thomas B.L., Nelson J.M., Diegelmann R.F. Characterization and quantitation of wound matrix in the fetal rabbit. Matrix. 9:1989;224-231.
8. Dunphy J.E., Udupa K.N. Chemical and histochemical sequences in the normal healing of wounds. New England Journal of Medicine. 253:1955;847-851.
9. Fleischmajer R., Fischer L.W., McDonald E.D., Jacobs L., Perlisch J.S., Termine J. Decorin interacts with fibrillar collagen of embryonic and adult human skin. Journal of Structural Biology. 106:1991;82-90.
10. Forrester J.V., Lackie J.M. Effect of hyaluronic acid on neutrophil adhesion. Journal of Cell Science. 50:1981;329-344.
11. Forrester J.V., Wilkinson P.C. Inhibition of leukocyte locomotion by hyaluronic acid. Journal of Cell Science. 48:1981;315-331.
12. Gallo, R.L., Bernfield, M., 1996. Proteoglycans and their role in wound repair. In: Clark, R.A.F. (Ed.), The Molecular and Cellular Biology of Wound Repair, 2nd ed. Plenum, New York.
13. Grindlay D., Reynolds T. The Aloe vera phenomenon: A review of the properties and modern uses of the leaf parenchyma gel. Journal of Ethnopharmacology. 16:1986;117-151.
14. Heggars J.P., Pelley R.P., Robson M.C. Beneficial effects of Aloe in wound healing. Phytotherapy Research. 7:1993;S48-S52.
15. Kawai Y., Anno K. Mucopolysaccharide degrading enzymes from the liver of squid Ommastre phesloni I. Hyaluronidase. Biochimica et Biophysica Acta. 242:1971;428-436.
16. Kojima T., Shworak N.W., Rosenberg R.D. Molecular cloning and expression of two distinct cDNA-encoding heparan sulfate proteoglycan core proteins from a rat endothelial cell line. Journal of Biological Chemistry. 267:1992;4870-4877.
17. Knudson C.B., Toole B.P. Changes in the pericellular matrix during differentiation of limb bud mesoderm. Developmental Biology. 112:1985;308-318.
18. Levvy G.A., Kerr L.M.H., Campbell J.G. Beta glucuronidase and cell proliferation. Biochemical Journal. 42:1948;462-468.
19. Mast B.A., Diegelmann R.F., Krummel T.M., Cohen I.K. Hyaluronic acid modulates proliferation, collagen and protein synthesis in cultured fetal fibroblasts. Matrix. 13:1993;441-446.
20. Miller M.B., Koltai P.J. Treatment of experimental frostbite with pentoxifylline and Aloe vera cream. Archives of Otolaryngology, Head and Neck Surgery. 121:1995;678-680.
21. Moore J.C., Morris J.E. A simple automated colorimetric method for determination of N-acetyl-β-D-glucosaminidase. Annals of Clinical Biochemistry. 19:1982;157-159.
22. Okasala O., Salo T., Tammi R., Hakkinen L., Jalkanen M., Inki P., Larjava H. Expression of proteoglycans and hyaluronan during wound healing. Journal of Histochemistry and Cytochemistry. 43:1995;125-135.
23. Parkinson J.F., Koyama T., Bang N.Y., Preissner K.T. Thrombomoduline: An anticoagulant cell surface proteoglycan with physiologically relevant glycosaminoglycan moiety. Advances in Experimental Medicine and Biology. 313:1992;177-188.
24. Raekallio J. Enzyme histochemistry of wound healing. Progress in Histochemistry and Cytochemistry. 1:1970;51-52.
25. Raghow R. The role of extracellular matrix in postinflammatory wound healing and fibrosis. FASEB Journal. 8:1994;823-831.
26. Roberts D.B., Travis E.L. Acemannan-containing wound dressing gel reduces radiation-induced skin reactions in C3H mice. International Journal of Radiation Oncology Biology Physics. 32:1995;1047-1052.
27. Schiller S., Slover G., Dorfman A.A. A method for the separation of acid mucopolysaccharides: Its application to the isolation of heparin from the skin of rats. Journal of Biological Chemistry. 236:1961;983-987.
28. Scott J.E. Proteoglycan fibrillar collagen interactions. Biochemical Journal. 252:1988;313-323.
29. Smith R.L., Gilkerson E., Kohatsu N., Merchant T., Schurman D.J. Quantitative microanalysis of synovial fluid and articular cartilage glycosaminoglycans. Analytical Biochemistry. 103:1980;191-200.
30. Toole, B.P., 1976. Morphogenetic role of glycosaminoglycans (acid mucopolysaccharides) in brain and other tissues. In: Barondes, S.H. (Ed.), Neuronal Recognition. Plenum, New York, pp. 275-329.
31. Turley E.A. The role of cell-associated hyaluronan-binding protein in fibroblast behaviour. Ciba Foundation Symposium. 143:1989;121-133.
32. Underhill C.B., Toole B.P. Binding of hyaluronate to the surface of cultured cells. Cell Biology. 82:1979;475-484.
33. Weissman G. The role of lysosomes in inflammation and disease. Annual Review of Medicine. 18:1967;97-112.