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Volumn 2015, Issue , 2015, Pages

Gremlin, a bone morphogenetic protein antagonist, is a crucial angiogenic factor in pituitary adenoma

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENIC FACTOR; BONE MORPHOGENETIC PROTEIN ANTAGONIST; CD34 ANTIGEN; GLYCOPROTEIN; GREMLIN; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

EID: 84925430972     PISSN: 16878337     EISSN: 16878345     Source Type: Journal    
DOI: 10.1155/2015/834137     Document Type: Article
Times cited : (10)

References (38)
  • 1
    • 84857731623 scopus 로고    scopus 로고
    • Imaging in the age ofmolecular medicine:monitoring of anti-angiogenic treatments
    • W. Lederle, M. Palmowski, and F. Kiessling, "Imaging in the age ofmolecular medicine:monitoring of anti-angiogenic treatments, " Current Pharmaceutical Biotechnology, vol. 13, no. 4, pp. 595-608, 2012.
    • (2012) Current Pharmaceutical Biotechnology , vol.13 , Issue.4 , pp. 595-608
    • Lederle, W.1    Palmowski, M.2    Kiessling, F.3
  • 2
    • 84855669275 scopus 로고    scopus 로고
    • Novel therapeutic approaches for targeting tumor angiogenesis
    • A. G. Linkous and E. M. Yazlovitskaya, "Novel therapeutic approaches for targeting tumor angiogenesis, " Anticancer Research, vol. 32, no. 1, pp. 1-12, 2012.
    • (2012) Anticancer Research , vol.32 , Issue.1 , pp. 1-12
    • Linkous, A.G.1    Yazlovitskaya, E.M.2
  • 3
    • 84866295392 scopus 로고    scopus 로고
    • Curcumin suppresses HIF1A synthesis and VEGFA release in pituitary adenomas
    • B. Shan, C. Schaaf, A. Schmidt et al. , "Curcumin suppresses HIF1A synthesis and VEGFA release in pituitary adenomas, " Journal of Endocrinology, vol. 214, no. 3, pp. 389-398, 2012.
    • (2012) Journal of Endocrinology , vol.214 , Issue.3 , pp. 389-398
    • Shan, B.1    Schaaf, C.2    Schmidt, A.3
  • 4
    • 84863369192 scopus 로고    scopus 로고
    • Erythropoietin promotes the growth of pituitary adenomas by enhancing angiogenesis
    • J. Yang, Z. Xiao, T. Li, X. Gu, and B. Fan, "Erythropoietin promotes the growth of pituitary adenomas by enhancing angiogenesis, " International Journal of Oncology, vol. 40, no. 4, pp. 1230-1237, 2012.
    • (2012) International Journal of Oncology , vol.40 , Issue.4 , pp. 1230-1237
    • Yang, J.1    Xiao, Z.2    Li, T.3    Gu, X.4    Fan, B.5
  • 5
    • 84855185784 scopus 로고    scopus 로고
    • Reduced expression of tissue factor pathway inhibitor-2 contributes to apoptosis and angiogenesis in cervical cancer
    • article 1
    • Q. Zhang, Y. Zhang, S. Z. Wang et al. , "Reduced expression of tissue factor pathway inhibitor-2 contributes to apoptosis and angiogenesis in cervical cancer, " Journal of Experimental and Clinical Cancer Research, vol. 31, no. 1, article 1, 2012.
    • (2012) Journal of Experimental and Clinical Cancer Research , vol.31 , Issue.1
    • Zhang, Q.1    Zhang, Y.2    Wang, S.Z.3
  • 6
    • 84863031064 scopus 로고    scopus 로고
    • A study of the suppressive effect on human pancreatic adenocarcinoma cell proliferation and angiogenesis by stable plasmid-based siRNA silencing of c-Src gene expression
    • X. Zhao, D. C. Li, H. Zhao et al. , "A study of the suppressive effect on human pancreatic adenocarcinoma cell proliferation and angiogenesis by stable plasmid-based siRNA silencing of c-Src gene expression, " Oncology Reports, vol. 27, no. 3, pp. 628-636, 2012.
    • (2012) Oncology Reports , vol.27 , Issue.3 , pp. 628-636
    • Zhao, X.1    Li, D.C.2    Zhao, H.3
  • 7
    • 84860295704 scopus 로고    scopus 로고
    • Norcantharidin: A potential antiangiogenic agent for gallbladder cancers in vitro and in vivo
    • J. T. Zhang, Y. Z. Fan, C. Q. Chen, Z. M. Zhao, and W. Sun, "Norcantharidin: a potential antiangiogenic agent for gallbladder cancers in vitro and in vivo, " International Journal of Oncology, vol. 40, no. 5, pp. 1501-1514, 2012.
    • (2012) International Journal of Oncology , vol.40 , Issue.5 , pp. 1501-1514
    • Zhang, J.T.1    Fan, Y.Z.2    Chen, C.Q.3    Zhao, Z.M.4    Sun, W.5
  • 8
    • 42049112971 scopus 로고    scopus 로고
    • Immunohistochemical analysis of VEGF-C/VEGFR-3 system and lymphatic vessel extent in normal and adenomatous human pituitary tissues
    • C. Onofri, M. Losa, E. Uhl, G. K. Stalla, and U. Renner, "Immunohistochemical analysis of VEGF-C/VEGFR-3 system and lymphatic vessel extent in normal and adenomatous human pituitary tissues, " Experimental and Clinical Endocrinology and Diabetes, vol. 116, no. 3, pp. 152-157, 2008.
    • (2008) Experimental and Clinical Endocrinology and Diabetes , vol.116 , Issue.3 , pp. 152-157
    • Onofri, C.1    Losa, M.2    Uhl, E.3    Stalla, G.K.4    Renner, U.5
  • 9
    • 33751036065 scopus 로고    scopus 로고
    • Localization of vascular endothelial growth factor (VEGF) receptors in normal and adenomatous pituitaries: Detection of a non-endothelial function of VEGF in pituitary tumours
    • C. Onofri, M. Theodoropoulou, M. Losa et al. , "Localization of vascular endothelial growth factor (VEGF) receptors in normal and adenomatous pituitaries: detection of a non-endothelial function of VEGF in pituitary tumours, " Journal of Endocrinology, vol. 191, no. 1, pp. 249-261, 2006.
    • (2006) Journal of Endocrinology , vol.191 , Issue.1 , pp. 249-261
    • Onofri, C.1    Theodoropoulou, M.2    Losa, M.3
  • 10
    • 16644378875 scopus 로고    scopus 로고
    • Regulation of VEGF-A, VEGFR-I, thrombospondin-1,-2, and-3 expression in a human pituitary cell line (HP75) by TGFβ1, bFGF, and EGF
    • H. Horiguchi, L. Jin, K. H. Ruebel, B. W. Scheithauer, and R. V. Lloyd, "Regulation of VEGF-A, VEGFR-I, thrombospondin-1,-2, and-3 expression in a human pituitary cell line (HP75) by TGFβ1, bFGF, and EGF, " Endocrine, vol. 24, no. 2, pp. 141-146, 2004.
    • (2004) Endocrine , vol.24 , Issue.2 , pp. 141-146
    • Horiguchi, H.1    Jin, L.2    Ruebel, K.H.3    Scheithauer, B.W.4    Lloyd, R.V.5
  • 11
    • 34249823374 scopus 로고    scopus 로고
    • Pasireotide, amultiple somatostatin receptor subtypes ligand, reduces cell viability in non-functioning pituitary adenomas by inhibiting vascular endothelial growth factor secretion
    • M. C. Zatelli, D. Piccin, C. Vignali et al. , "Pasireotide, amultiple somatostatin receptor subtypes ligand, reduces cell viability in non-functioning pituitary adenomas by inhibiting vascular endothelial growth factor secretion, " Endocrine-Related Cancer, vol. 14, no. 1, pp. 91-102, 2007.
    • (2007) Endocrine-Related Cancer , vol.14 , Issue.1 , pp. 91-102
    • Zatelli, M.C.1    Piccin, D.2    Vignali, C.3
  • 12
    • 34447109798 scopus 로고    scopus 로고
    • The pituitary tumor-transforming gene promotes angiogenesis in a mouse model of follicular thyroid cancer
    • C. S. Kim, H. Ying, M. C. Willingham, and S. Y. Cheng, "The pituitary tumor-transforming gene promotes angiogenesis in a mouse model of follicular thyroid cancer, " Carcinogenesis, vol. 28, no. 5, pp. 932-939, 2007.
    • (2007) Carcinogenesis , vol.28 , Issue.5 , pp. 932-939
    • Kim, C.S.1    Ying, H.2    Willingham, M.C.3    Cheng, S.Y.4
  • 13
    • 33751540132 scopus 로고    scopus 로고
    • Pituitary tumor transforming gene (PTTG) stimulates thyroid cell proliferation via a vascular endothelial growth factor/kinase insert domain receptor/ inhibitor of DNA binding-3 autocrine pathway
    • D. S. Kim, J. A. Franklyn, K. Boelaert, M. C. Eggo, J. C. Watkinson, and C. J. McCabe, "Pituitary tumor transforming gene (PTTG) stimulates thyroid cell proliferation via a vascular endothelial growth factor/kinase insert domain receptor/ inhibitor of DNA binding-3 autocrine pathway, " Journal of Clinical Endocrinology andMetabolism, vol. 91, no. 11, pp. 4603-4611, 2006.
    • (2006) Journal of Clinical Endocrinology AndMetabolism , vol.91 , Issue.11 , pp. 4603-4611
    • Kim, D.S.1    Franklyn, J.A.2    Boelaert, K.3    Eggo, M.C.4    Watkinson, J.C.5    McCabe, C.J.6
  • 14
    • 33644828755 scopus 로고    scopus 로고
    • Pituitary tumortransforming gene regulates multiple downstream angiogenic genes in thyroid cancer
    • D. S. Kim, J. A. Franklyn, A. L. Stratford et al. , "Pituitary tumortransforming gene regulates multiple downstream angiogenic genes in thyroid cancer, " The Journal of Clinical Endocrinology andMetabolism, vol. 91, no. 3, pp. 1119-1128, 2006.
    • (2006) The Journal of Clinical Endocrinology AndMetabolism , vol.91 , Issue.3 , pp. 1119-1128
    • Kim, D.S.1    Franklyn, J.A.2    Stratford, A.L.3
  • 15
    • 33746840099 scopus 로고    scopus 로고
    • Microvascular density and vascular endothelial growth factor have little correlation with prognosis of craniopharyngioma
    • J. Xu, S. Zhang, C. You, X. Wang, and Q. Zhou, "Microvascular density and vascular endothelial growth factor have little correlation with prognosis of craniopharyngioma, " Surgical Neurology, vol. 66, supplement 1, pp. S30-S34, 2006.
    • (2006) Surgical Neurology , vol.66 , pp. S30-S34
    • Xu, J.1    Zhang, S.2    You, C.3    Wang, X.4    Zhou, Q.5
  • 16
    • 33847402760 scopus 로고    scopus 로고
    • Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factor
    • H. Stabile, S. Mitola, E. Moroni et al. , "Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factor, " Blood, vol. 109, no. 5, pp. 1834-1840, 2007.
    • (2007) Blood , vol.109 , Issue.5 , pp. 1834-1840
    • Stabile, H.1    Mitola, S.2    Moroni, E.3
  • 17
    • 84871613076 scopus 로고    scopus 로고
    • Involvement of alpha(v)beta (3) integrin in gremlin-induced angiogenesi
    • C. Ravelli, S. Mitola, M. Corsini, and M. Presta, "Involvement of alpha(v)beta (3) integrin in gremlin-induced angiogenesi, " Angiogenesis, vol. 16, no. 1, pp. 235-243, 2013.
    • (2013) Angiogenesis , vol.16 , Issue.1 , pp. 235-243
    • Ravelli, C.1    Mitola, S.2    Corsini, M.3    Presta, M.4
  • 18
    • 78149347762 scopus 로고    scopus 로고
    • Gremlin: Vexing VEGF receptor agonist
    • L. Claesson-Welsh, "Gremlin: vexing VEGF receptor agonist, " Blood, vol. 116, no. 18, pp. 3386-3387, 2010.
    • (2010) Blood , vol.116 , Issue.18 , pp. 3386-3387
    • Claesson-Welsh, L.1
  • 19
    • 84865725562 scopus 로고    scopus 로고
    • Role of nanomechanics in canonical and noncanonical pro-angiogenic ligand/VEGF receptor-2 activation
    • D. Maiolo, S. Mitola, D. Leali et al. , "Role of nanomechanics in canonical and noncanonical pro-angiogenic ligand/VEGF receptor-2 activation, " Journal of the American Chemical Society, vol. 134, no. 35, pp. 14573-14579, 2012.
    • (2012) Journal of the American Chemical Society , vol.134 , Issue.35 , pp. 14573-14579
    • Maiolo, D.1    Mitola, S.2    Leali, D.3
  • 20
    • 0346731134 scopus 로고    scopus 로고
    • Antagonists of Wnt and BMP signaling promote the formation of vertebrate head muscle
    • E. Tzahor, H. Kempf, R. C. Mootoosamy et al. , "Antagonists of Wnt and BMP signaling promote the formation of vertebrate head muscle, " Genes and Development, vol. 17, no. 24, pp. 3087-3099, 2003.
    • (2003) Genes and Development , vol.17 , Issue.24 , pp. 3087-3099
    • Tzahor, E.1    Kempf, H.2    Mootoosamy, R.C.3
  • 21
    • 84864749532 scopus 로고    scopus 로고
    • Gremlin is overexpressed in lung adenocarcinoma and increases cell growth and proliferation in normal lung cells
    • Article ID e42264
    • M. S. Mulvihill, Y.-W. Kwon, S. Lee et al. , "Gremlin is overexpressed in lung adenocarcinoma and increases cell growth and proliferation in normal lung cells, " PLoS ONE, vol. 7, no. 8, Article ID e42264, 2012.
    • (2012) PLoS ONE , vol.7 , Issue.8
    • Mulvihill, M.S.1    Kwon, Y.-W.2    Lee, S.3
  • 22
    • 84880693575 scopus 로고    scopus 로고
    • Antagonism and synergy between extracellular BMP modulators Tsg and BMPER balance blood vessel formation
    • J. Heinke, M. Juschkat, A. Charlet et al. , "Antagonism and synergy between extracellular BMP modulators Tsg and BMPER balance blood vessel formation, " Journal of Cell Science, vol. 126, no. 14, pp. 3082-3094, 2013.
    • (2013) Journal of Cell Science , vol.126 , Issue.14 , pp. 3082-3094
    • Heinke, J.1    Juschkat, M.2    Charlet, A.3
  • 23
    • 84872487704 scopus 로고    scopus 로고
    • Expression of gremlin 1 correlates with increased angiogenesis and progression-free survival in patients with pancreatic neuroendocrine tumors
    • M.-H. Chen, Y.-C. Yeh, Y.-M. Shyr et al. , "Expression of gremlin 1 correlates with increased angiogenesis and progression-free survival in patients with pancreatic neuroendocrine tumors, " Journal of Gastroenterology, vol. 48, no. 1, pp. 101-108, 2013.
    • (2013) Journal of Gastroenterology , vol.48 , Issue.1 , pp. 101-108
    • Chen, M.-H.1    Yeh, Y.-C.2    Shyr, Y.-M.3
  • 24
    • 12344262661 scopus 로고    scopus 로고
    • Skeletal overexpression of gremlin impairs bone formation and causes osteopenia
    • E. Gazzerro, R. C. Pereira, V. Jorgetti, S. Olson, A. N. Economides, and E. Canalis, "Skeletal overexpression of gremlin impairs bone formation and causes osteopenia, " Endocrinology, vol. 146, no. 2, pp. 655-665, 2005.
    • (2005) Endocrinology , vol.146 , Issue.2 , pp. 655-665
    • Gazzerro, E.1    Pereira, R.C.2    Jorgetti, V.3    Olson, S.4    Economides, A.N.5    Canalis, E.6
  • 25
    • 34447550603 scopus 로고    scopus 로고
    • Reduction of BMP4 activity by gremlin 1 enables ureteric bud outgrowth and GDNF/WNT11 feedback signalling during kidney branching morphogenesis
    • O. Michos, A. Goncalves, J. Lopez-Rios et al. , "Reduction of BMP4 activity by gremlin 1 enables ureteric bud outgrowth and GDNF/WNT11 feedback signalling during kidney branching morphogenesis, " Development, vol. 134, no. 13, pp. 2397-2405, 2007.
    • (2007) Development , vol.134 , Issue.13 , pp. 2397-2405
    • Michos, O.1    Goncalves, A.2    Lopez-Rios, J.3
  • 26
    • 35748953461 scopus 로고    scopus 로고
    • Conditional deletion of gremlin causes a transient increase in bone formation and bone mass
    • E. Gazzerro, A. Smerdel-Ramoya, S. Zanotti et al. , "Conditional deletion of gremlin causes a transient increase in bone formation and bone mass, "The Journal of Biological Chemistry, vol. 282, no. 43, pp. 31549-31557, 2007.
    • (2007) The Journal of Biological Chemistry , vol.282 , Issue.43 , pp. 31549-31557
    • Gazzerro, E.1    Smerdel-Ramoya, A.2    Zanotti, S.3
  • 27
    • 77952027256 scopus 로고    scopus 로고
    • Hypoxia decreases sclerostin expression and increases Wnt signaling in osteoblasts
    • D. C. Genetos, C. A. Toupadakis, L. F. Raheja et al. , "Hypoxia decreases sclerostin expression and increases Wnt signaling in osteoblasts, " Journal of Cellular Biochemistry, vol. 110, no. 2, pp. 457-467, 2010.
    • (2010) Journal of Cellular Biochemistry , vol.110 , Issue.2 , pp. 457-467
    • Genetos, D.C.1    Toupadakis, C.A.2    Raheja, L.F.3
  • 28
    • 78149300188 scopus 로고    scopus 로고
    • Gremlin is a novel agonist of the major proangiogenic receptor VEGFR2
    • S. Mitola, C. Ravelli, E. Moroni et al. , "Gremlin is a novel agonist of the major proangiogenic receptor VEGFR2, " Blood, vol. 116, no. 18, pp. 3677-3680, 2010.
    • (2010) Blood , vol.116 , Issue.18 , pp. 3677-3680
    • Mitola, S.1    Ravelli, C.2    Moroni, E.3
  • 29
    • 33749528535 scopus 로고    scopus 로고
    • Bone morphogenetic protein antagonist gremlin 1 is wideley expressed by cancer-associated stromal cells and can promote tumor cell proliferation
    • J. B. Sneddon, H. H. Zhen, K. Montgomery et al. , "Bone morphogenetic protein antagonist gremlin 1 is wideley expressed by cancer-associated stromal cells and can promote tumor cell proliferation, " Proceedings of theNational Academy of Sciences of the United States of America, vol. 103, no. 40, pp. 14842-14847, 2006.
    • (2006) Proceedings of TheNational Academy of Sciences of the United States of America , vol.103 , Issue.40 , pp. 14842-14847
    • Sneddon, J.B.1    Zhen, H.H.2    Montgomery, K.3
  • 31
    • 0036385254 scopus 로고    scopus 로고
    • Gremlin: An example of the re-emergence of developmental programmes in diabetic nephropathy
    • D. W. P. Lappin, R. McMahon, M. Murphy, and H. R. Brady, "Gremlin: an example of the re-emergence of developmental programmes in diabetic nephropathy, " Nephrology Dialysis Transplantation, vol. 17, supplement 9, pp. 65-67, 2002.
    • (2002) Nephrology Dialysis Transplantation , vol.17 , pp. 65-67
    • Lappin, D.W.P.1    McMahon, R.2    Murphy, M.3    Brady, H.R.4
  • 32
    • 64949178482 scopus 로고    scopus 로고
    • Bone morphogenetic protein-7 and Gremlin: New emerging therapeutic targets for diabetic nephropathy
    • Y. Zhang and Q. Zhang, "Bone morphogenetic protein-7 and Gremlin: new emerging therapeutic targets for diabetic nephropathy, " Biochemical and Biophysical Research Communications, vol. 383, no. 1, pp. 1-3, 2009.
    • (2009) Biochemical and Biophysical Research Communications , vol.383 , Issue.1 , pp. 1-3
    • Zhang, Y.1    Zhang, Q.2
  • 34
    • 20444364531 scopus 로고    scopus 로고
    • Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy
    • V. Dolan, M. Murphy, D. Sadlier et al. , "Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy, " American Journal of Kidney Diseases, vol. 45, no. 6, pp. 1034-1039, 2005.
    • (2005) American Journal of Kidney Diseases , vol.45 , Issue.6 , pp. 1034-1039
    • Dolan, V.1    Murphy, M.2    Sadlier, D.3
  • 35
    • 28444435554 scopus 로고    scopus 로고
    • Gremlin gene expression in bovine retinal pericytes exposed to elevated glucose
    • R. Kane, L. Stevenson, C. Godson, A. W. Stitt, and C. OBrien, "Gremlin gene expression in bovine retinal pericytes exposed to elevated glucose, " British Journal of Ophthalmology, vol. 89, no. 12, pp. 1638-1642, 2005.
    • (2005) British Journal of Ophthalmology , vol.89 , Issue.12 , pp. 1638-1642
    • Kane, R.1    Stevenson, L.2    Godson, C.3    Stitt, A.W.4    Obrien, C.5
  • 37
    • 79951844946 scopus 로고    scopus 로고
    • Wnt signaling in estrogen-induced lactotroph proliferation
    • A. Giles, F. Madec, S. Friedrichsen et al. , "Wnt signaling in estrogen-induced lactotroph proliferation, " Journal of Cell Science, vol. 124, no. 4, pp. 540-547, 2011.
    • (2011) Journal of Cell Science , vol.124 , Issue.4 , pp. 540-547
    • Giles, A.1    Madec, F.2    Friedrichsen, S.3
  • 38
    • 77955321041 scopus 로고    scopus 로고
    • Identification of Wnt family inhibitors: A pituitary tumor directedwhole genome approach
    • M. S. Elston and R. J. Clifton-Bligh, "Identification of Wnt family inhibitors: a pituitary tumor directedwhole genome approach, " Molecular and Cellular Endocrinology, vol. 326, no. 1-2, pp. 48-54, 2010.
    • (2010) Molecular and Cellular Endocrinology , vol.326 , Issue.1-2 , pp. 48-54
    • Elston, M.S.1    Clifton-Bligh, R.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.