Role of nanomechanics in canonical and noncanonical pro-angiogenic ligand/VEGF receptor-2 activation

Journal of the American Chemical Society

Volumn 134, Issue 35, 2012, Pages 14573-14579

  Maiolo, Daniele ^a,b   Mitola, Stefania ^b   Leali, Daria ^b   Oliviero, Giulio ^a   Ravelli, Cosetta ^b   Bugatti, Antonella ^b   Depero, Laura E ^a   Presta, Marco ^b   Bergese, Paolo ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS; ANGIOGENIC FACTOR; BINDING AFFINITIES; BINDING KINETICS; CONFORMATIONAL CHANGE; DATA POINTS; EXTRACELLULAR DOMAINS; INTERMOLECULAR FORCES; INTERMOLECULAR INTERACTIONS; INTRACELLULAR SIGNALING; MITOGENIC RESPONSE; NANO SCALE; THERAPEUTIC TARGETS; VASCULAR ENDOTHELIAL GROWTH FACTOR; VEGFR-2;

BINDING ENERGY; BIOACTIVITY; BIOSENSORS; CELL MEMBRANES; CHEMICAL BONDS; CYTOLOGY; ENDOTHELIAL CELLS;

LIGANDS;

ANGIOGENIC FACTOR; MITOGENIC AGENT; PROANGIOGENIC LIGAND; RECOMBINANT VASCULOTROPIN; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2;

ARTICLE; BINDING AFFINITY; BINDING KINETICS; BIOLOGICAL ACTIVITY; BIOSENSOR; CANONICAL ANALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMMOBILIZED CELL; INTRACELLULAR SIGNALING; LIGAND BINDING; MOLECULAR INTERACTION; MOLECULAR MECHANICS; NANOANALYSIS; NANOMECHANICAL BIOSENSOR; NANOSENSOR; NONCANONICAL ANALYSIS; PROTEIN INTERACTION; SURFACE PROPERTY;

FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; MECHANICAL PROCESSES; NANOTECHNOLOGY; NEOVASCULARIZATION, PHYSIOLOGIC; SURFACE PLASMON RESONANCE; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 84865725562     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja305816p     Document Type: Article

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