-
1
-
-
34250761346
-
Lung cancer: Future directions
-
Lam WK and Watkins DN: Lung cancer: future directions. Respirology 12: 471‑477, 2007.
-
(2007)
Respirology
, vol.12
, pp. 471-477
-
-
Lam, W.K.1
Watkins, D.N.2
-
2
-
-
0029084805
-
Interleukin‑6 family of cytokines and gp130
-
Kishimoto T, Akira S, Narazaki M and Taga T: Interleukin‑6 family of cytokines and gp130. Blood 86: 1243‑1254, 1995.
-
(1995)
Blood
, vol.86
, pp. 1243-1254
-
-
Kishimoto, T.1
Akira, S.2
Narazaki, M.3
Taga, T.4
-
3
-
-
27544476971
-
The role of il‑6 and stat3 in inflammation and cancer
-
Hodge DR, Hurt EM and Farrar WL: The role of IL‑6 and STAT3 in inflammation and cancer. Eur J Cancer 41: 2502‑2512, 2005.
-
(2005)
Eur J Cancer
, vol.41
, pp. 2502-2512
-
-
Hodge, D.R.1
Hurt, E.M.2
Farrar, W.L.3
-
4
-
-
3042823539
-
Serum levels of il‑6 and tnf‑alpha correlate with clinicopathological features and patient survival in patients with prostate cancer
-
Michalaki V, Syrigos K, Charles P and Waxman J: Serum levels of IL‑6 and TNF‑alpha correlate with clinicopathological features and patient survival in patients with prostate cancer. Br J Cancer 90: 2312‑2316, 2004.
-
(2004)
Br J Cancer
, vol.90
, pp. 2312-2316
-
-
Michalaki, V.1
Syrigos, K.2
Charles, P.3
Waxman, J.4
-
5
-
-
0028203595
-
Interleukin‑6 level in serum and ascites as a prognostic factor in patients with epithelial ovarian cancer
-
Plante M, Rubin SC, Wong GY, Federici MG, Finstad CL and Gastl GA: Interleukin‑6 level in serum and ascites as a prognostic factor in patients with epithelial ovarian cancer. Cancer 73: 1882‑1888, 1994.
-
(1994)
Cancer
, vol.73
, pp. 1882-1888
-
-
Plante, M.1
Rubin, S.C.2
Wong, G.Y.3
Federici, M.G.4
Finstad, C.L.5
Gastl, G.A.6
-
6
-
-
0033036097
-
Serum interleukin‑6 levels correlate to tumor progression and prognosis in metastatic breast carcinoma
-
Zhang GJ and Adachi I: Serum interleukin‑6 levels correlate to tumor progression and prognosis in metastatic breast carcinoma. Anticancer Res 19: 1427‑1432, 1999.
-
(1999)
Anticancer Res
, vol.19
, pp. 1427-1432
-
-
Zhang, G.J.1
Adachi, I.2
-
7
-
-
0042209597
-
Serum interleukin‑6 levels reflect the disease status of colorectal cancer
-
Chung YC and Chang YF: Serum interleukin‑6 levels reflect the disease status of colorectal cancer. J Surg Oncol 83: 222‑226, 2003.
-
(2003)
J Surg Oncol
, vol.83
, pp. 222-226
-
-
Chung, Y.C.1
Chang, Y.F.2
-
8
-
-
43649104094
-
The recombinant humanized anti‑il‑6 receptor antibody tocilizumab, an innovative drug for the treatment of rheumatoid arthritis
-
Ohsugi Y and Kishimoto T: The recombinant humanized anti‑IL‑6 receptor antibody tocilizumab, an innovative drug for the treatment of rheumatoid arthritis. Expert Opin Biol Ther 8: 669‑681, 2008.
-
(2008)
Expert Opin Biol Ther
, vol.8
, pp. 669-681
-
-
Ohsugi, Y.1
Kishimoto, T.2
-
9
-
-
40749155784
-
Tocilizumab for rheumatoid and juvenile idiopathic arthritis
-
Bongartz T: Tocilizumab for rheumatoid and juvenile idiopathic arthritis. Lancet 371: 961‑963, 2008.
-
(2008)
Lancet
, vol.371
, pp. 961-963
-
-
Bongartz, T.1
-
10
-
-
68849107757
-
Antitumor effect of humanized anti‑interleukin‑6 receptor antibody (tocilizumab) on glioma cell proliferation. Laboratory investigation
-
Kudo M, Jono H, Shinriki S, Yano S, Nakamura H, Makino K, Hide T, Muta D, Ueda M, Ota K, et al: Antitumor effect of humanized anti‑interleukin‑6 receptor antibody (tocilizumab) on glioma cell proliferation. Laboratory investigation. J Neurosurg 111:219‑225, 2009.
-
(2009)
J Neurosurg
, vol.111
, pp. 219-225
-
-
Kudo, M.1
Jono, H.2
Shinriki, S.3
Yano, S.4
Nakamura, H.5
Makino, K.6
Hide, T.7
Muta, D.8
Ueda, M.9
Ota, K.10
-
11
-
-
33244459396
-
Autocrine interleukin‑6/interleukin‑6 receptor stimulation in non‑small‑cell lung cancer
-
Haura EB, Livingston S and Coppola D: Autocrine interleukin‑6/interleukin‑6 receptor stimulation in non‑small‑cell lung cancer. Clin Lung Cancer 7: 273‑275, 2006.
-
(2006)
Clin Lung Cancer
, vol.7
, pp. 273-275
-
-
Haura, E.B.1
Livingston, S.2
Coppola, D.3
-
12
-
-
84862902822
-
Blockade of interleukin‑6 receptor suppresses the proliferation of h460 lung cancer stem cells
-
Yi H, Cho HJ, Cho SM, Jo K, Park JA, Kim NH, Amidon GL, Kim JS and Shin HC: Blockade of interleukin‑6 receptor suppresses the proliferation of H460 lung cancer stem cells. Int J Oncol 41: 310‑316, 2012.
-
(2012)
Int J Oncol
, vol.41
, pp. 310-316
-
-
Yi, H.1
Cho, H.J.2
Cho, S.M.3
Jo, K.4
Park, J.A.5
Kim, N.H.6
Amidon, G.L.7
Kim, J.S.8
Shin, H.C.9
-
13
-
-
41049096935
-
Effect of compressive force on the expression of inflammatory cytokines and their receptors in osteoblastic saos‑2 cells
-
Koyama Y, Mitsui N, Suzuki N, Yanagisawa M, Sanuki R, Isokawa K, Shimizu N and Maeno M: Effect of compressive force on the expression of inflammatory cytokines and their receptors in osteoblastic Saos‑2 cells. Arch Oral Biol 53: 488‑496, 2008.
-
(2008)
Arch Oral Biol
, vol.53
, pp. 488-496
-
-
Koyama, Y.1
Mitsui, N.2
Suzuki, N.3
Yanagisawa, M.4
Sanuki, R.5
Isokawa, K.6
Shimizu, N.7
Maeno, M.8
-
14
-
-
80051616701
-
Down‑regulation of expression of interleukin‑6 and its receptor results in growth inhibition of mcf‑7 breast cancer cells
-
Jiang XP, Yang DC, Elliott RL and Head JF: Down‑regulation of expression of interleukin‑6 and its receptor results in growth inhibition of MCF‑7 breast cancer cells. Anticancer Res 31: 2899‑2906, 2011.
-
(2011)
Anticancer Res
, vol.31
, pp. 2899-2906
-
-
Jiang, X.P.1
Yang, D.C.2
Elliott, R.L.3
Head, J.F.4
-
15
-
-
84891847947
-
Targeting interleukin‑6 in inflammatory autoimmune diseases and cancers
-
Yao X, Huang J, Zhong H, Shen N, Faggioni R, Fung M and Yao Y: Targeting interleukin‑6 in inflammatory autoimmune diseases and cancers. Pharmacol Ther 141: 125‑139, 2014.
-
(2014)
Pharmacol Ther
, vol.141
, pp. 125-139
-
-
Yao, X.1
Huang, J.2
Zhong, H.3
Shen, N.4
Faggioni, R.5
Fung, M.6
Yao, Y.7
-
16
-
-
83255176682
-
Randomised phase ii study of siltuximab (cnto 328), an anti‑il‑6 monoclonal antibody, in combination with mitoxantrone/prednisone versus mitoxantrone/ prednisone alone in metastatic castration‑resistant prostate cancer
-
Fizazi K, De Bono JS, Flechon A, Heidenreich A, Voog E, Davis NB, Qi M, Bandekar R, Vermeulen JT, Cornfeld M and Hudes GR: Randomised phase II study of siltuximab (CNTO 328), an anti‑IL‑6 monoclonal antibody, in combination with mitoxantrone/prednisone versus mitoxantrone/ prednisone alone in metastatic castration‑resistant prostate cancer. Eur J Cancer 48: 85‑93, 2012.
-
(2012)
Eur J Cancer
, vol.48
, pp. 85-93
-
-
Fizazi, K.1
De Bono, J.S.2
Flechon, A.3
Heidenreich, A.4
Voog, E.5
Davis, N.B.6
Qi, M.7
Bandekar, R.8
Vermeulen, J.T.9
Cornfeld, M.10
Hudes, G.R.11
-
17
-
-
79951556761
-
Blockade of interleukin‑6 signalling with siltuximab enhances melphalan cytotoxicity in preclinical models of multiple myeloma
-
Hunsucker SA, Magarotto V, Kuhn DJ, Kornblau SM, Wang M, Weber DM, Thomas SK, Shah JJ, Voorhees PM, Xie H, et al: Blockade of interleukin‑6 signalling with siltuximab enhances melphalan cytotoxicity in preclinical models of multiple myeloma. Br J Haematol 152: 579‑592, 2011.
-
(2011)
Br J Haematol
, vol.152
, pp. 579-592
-
-
Hunsucker, S.A.1
Magarotto, V.2
Kuhn, D.J.3
Kornblau, S.M.4
Wang, M.5
Weber, D.M.6
Thomas, S.K.7
Shah, J.J.8
Voorhees, P.M.9
Xie, H.10
-
18
-
-
79551663713
-
Anti‑interleukin‑6 receptor antibody inhibits the progression in human colon carcinoma cells
-
Hsu CP, Chen YL, Huang CC, Chou CC, Liu CL, Hung CH, Kao TY and Chung YC: Anti‑interleukin‑6 receptor antibody inhibits the progression in human colon carcinoma cells. Eur J Clin Invest 41: 277‑284, 2011.
-
(2011)
Eur J Clin Invest
, vol.41
, pp. 277-284
-
-
Hsu, C.P.1
Chen, Y.L.2
Huang, C.C.3
Chou, C.C.4
Liu, C.L.5
Hung, C.H.6
Kao, T.Y.7
Chung, Y.C.8
-
19
-
-
0034599429
-
Interleukin‑6 stimulates clonogenic growth of primary and metastatic human colon carcinoma cells
-
Schneider MR, Hoeflich A, Fischer JR, Wolf E, Sordat B and Lahm H: Interleukin‑6 stimulates clonogenic growth of primary and metastatic human colon carcinoma cells. Cancer Lett 151: 31‑38, 2000.
-
(2000)
Cancer Lett
, vol.151
, pp. 31-38
-
-
Schneider, M.R.1
Hoeflich, A.2
Fischer, J.R.3
Wolf, E.4
Sordat, B.5
Lahm, H.6
-
20
-
-
84889790196
-
Early intervention in the treatment of rheumatoid arthritis: Focus on tocilizumab
-
Yilmaz S and Simsek I: Early intervention in the treatment of rheumatoid arthritis: focus on tocilizumab. Ther Clin Risk Manag 9: 403‑408, 2013.
-
(2013)
Ther Clin Risk Manag
, vol.9
, pp. 403-408
-
-
Yilmaz, S.1
Simsek, I.2
-
21
-
-
64949203166
-
Tocilizumab: A review of its use in the management of rheumatoid arthritis
-
Oldfield V, Dhillon S and Plosker GL: Tocilizumab: a review of its use in the management of rheumatoid arthritis. Drugs 69: 609‑632, 2009.
-
(2009)
Drugs
, vol.69
, pp. 609-632
-
-
Oldfield, V.1
Dhillon, S.2
Plosker, G.L.3
-
22
-
-
0025990893
-
Murine anti‑interleukin‑6 monoclonal antibody therapy for a patient with plasma cell leukemia
-
Klein B, Wijdenes J, Zhang XG, Jourdan M, Boiron JM, Brochier J, Liautard J, Merlin M, Clement C Morel‑Fournier B,et al: Murine anti‑interleukin‑6 monoclonal antibody therapy for a patient with plasma cell leukemia. Blood 78: 1198‑1204, 1991.
-
(1991)
Blood
, vol.78
, pp. 1198-1204
-
-
Klein, B.1
Wijdenes, J.2
Zhang, X.G.3
Jourdan, M.4
Boiron, J.M.5
Brochier, J.6
Liautard, J.7
Merlin, M.8
Clement, C.9
Morel‑Fournier, B.10
-
23
-
-
0027502201
-
Reshaping a human antibody to inhibit the interleukin 6‑dependent tumor cell growth
-
Sato K, Tsuchiya M, Saldanha J, Koishihara Y, Ohsugi Y, Kishimoto T and Bendig MM: Reshaping a human antibody to inhibit the interleukin 6‑dependent tumor cell growth. Cancer Res 53: 851‑856, 1993.
-
(1993)
Cancer Res
, vol.53
, pp. 851-856
-
-
Sato, K.1
Tsuchiya, M.2
Saldanha, J.3
Koishihara, Y.4
Ohsugi, Y.5
Kishimoto, T.6
Bendig, M.M.7
-
24
-
-
84866182508
-
Ras inhibition in hepatocarcinoma by s‑trans‑trans‑farnesylthiosalicyclic acid: Association of its tumor preventive effect with cell proliferation, cell cycle events and angiogenesis
-
Stärkel P, Charette N, Borbath I, Schneider-Merck, T, De Saeger C, Abarca J, Leclercq I and Horsmans Y: Ras inhibition in hepatocarcinoma by S‑trans‑trans‑farnesylthiosalicyclic acid: association of its tumor preventive effect with cell proliferation, cell cycle events and angiogenesis. Mol Carcinog 51: 816‑825, 2012.
-
(2012)
Mol Carcinog
, vol.51
, pp. 816-825
-
-
Stärkel, P.1
Charette, N.2
Borbath, I.3
Schneider-Merck, T.4
De Saeger, C.5
Abarca, J.6
Leclercq, I.7
Horsmans, Y.8
-
25
-
-
84897546922
-
To nfκb or not to nfκb: The dilemma on how to inhibit a cancer cell fate regulator
-
Sorriento D, Illario M, Finelli R and Iaccarino G: To NFκB or not to NFκB: The Dilemma on How to Inhibit a Cancer Cell Fate Regulator. Transl Med UniSa 4: 73‑85, 2012.
-
(2012)
Transl Med Unisa
, vol.4
, pp. 73-85
-
-
Sorriento, D.1
Illario, M.2
Finelli, R.3
Iaccarino, G.4
-
26
-
-
84899113169
-
Nfκb function and regulation in cutaneous t‑cell lymphoma
-
Chang TP and Vancurova I: NFκB function and regulation in cutaneous T‑cell lymphoma. Am J Cancer Res 3: 433‑445, 2013.
-
(2013)
Am J Cancer Res
, vol.3
, pp. 433-445
-
-
Chang, T.P.1
Vancurova, I.2
-
27
-
-
77955720243
-
Nfκb anti‑apoptotic or pro‑apoptotic, maybe both
-
Martin AG: NFκB anti‑apoptotic or pro‑apoptotic, maybe both. Cell Cycle 9: 3131‑3132, 2010.
-
(2010)
Cell Cycle
, vol.9
, pp. 3131-3132
-
-
Martin, A.G.1
-
28
-
-
11844269840
-
Phosphorylation of nf‑kappab and ikappab proteins: Implications in cancer and inflammation
-
Viatour P, Merville MP, Bours V and Chariot A: Phosphorylation of NF‑kappaB and IkappaB proteins: implications in cancer and inflammation. Trends Biochem Sci 30: 43‑52, 2005.
-
(2005)
Trends Biochem Sci
, vol.30
, pp. 43-52
-
-
Viatour, P.1
Merville, M.P.2
Bours, V.3
Chariot, A.4
|