Prediction of VH-VL domain orientation for antibody variable domain modeling

Proteins: Structure, Function and Bioinformatics

Volumn 83, Issue 4, 2015, Pages 681-695

  Bujotzek, Alexander ^a   Dunbar, James ^b   Lipsmeier, Florian ^a   Schäfer, Wolfgang ^a   Antes, Iris ^c   Deane, Charlotte M ^b   Georges, Guy ^a  

^a ROCHE INNOVATION CENTER MUNICH   (Germany)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Antibody structure; Homology modeling; Protein domain orientation; Protein engineering

Indexed keywords

ANTIBODY; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN VARIABLE REGION;

ANTIBODY ENGINEERING; ANTIBODY SPECIFICITY; ANTIBODY STRUCTURE; ARTICLE; CRYSTAL STRUCTURE; PREDICTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN ENGINEERING; CHEMICAL STRUCTURE; CHEMISTRY; IMMUNOGLOBULIN VARIABLE REGION; PROTEIN DATABASE; SEQUENCE ANALYSIS; STRUCTURAL HOMOLOGY;

DATABASES, PROTEIN; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MODELS, MOLECULAR; PROTEIN ENGINEERING; SEQUENCE ANALYSIS, PROTEIN; STRUCTURAL HOMOLOGY, PROTEIN;

EID: 84925342012     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.24756     Document Type: Article

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