-
1
-
-
0034655131
-
WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer
-
Bednarek AK,Laflin KJ,Daniel RL,Liao Q,Hawkins KA,Aldaz CM.WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer.Cancer Res. 2000;60:2140-5
-
(2000)
Cancer Res
, vol.60
, pp. 2140-2145
-
-
Bednarek, A.K.1
Laflin, K.J.2
Daniel, R.L.3
Liao, Q.4
Hawkins, K.A.5
Aldaz, C.M.6
-
2
-
-
17444440946
-
Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells
-
Ried K,Finnis M,Hobson L,Mangelsdorf M,Dayan S,Nancarrow JK,Woollatt E,Kremmidiotis G,Gardner A,Venter D,Baker E,Richards RI.Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells.Hum Mol Genet. 2000;9:1651-63
-
(2000)
Hum Mol Genet
, vol.9
, pp. 1651-1663
-
-
Ried, K.1
Finnis, M.2
Hobson, L.3
Mangelsdorf, M.4
Dayan, S.5
Nancarrow, J.K.6
Woollatt, E.7
Kremmidiotis, G.8
Gardner, A.9
Venter, D.10
Baker, E.11
Richards, R.I.12
-
3
-
-
0035793612
-
Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity
-
Chang NS,Pratt N,Heath J,Schultz L,Sleve D,Carey GB,Zevotek N.Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity.J Biol Chem. 2001;276:3361-70
-
(2001)
J Biol Chem
, vol.276
, pp. 3361-3370
-
-
Chang, N.S.1
Pratt, N.2
Heath, J.3
Schultz, L.4
Sleve, D.5
Carey, G.B.6
Zevotek, N.7
-
4
-
-
0036266065
-
The common fragile site FRA16D and its associated gene WWOX are highly conserved in the mouse at Fra8E1
-
Krummel KA,Denison SR,Calhoun E,Phillips LA,Smith DI.The common fragile site FRA16D and its associated gene WWOX are highly conserved in the mouse at Fra8E1.Genes Chromosomes Cancer. 2002;34:154-67
-
(2002)
Genes Chromosomes Cancer
, vol.34
, pp. 154-167
-
-
Krummel, K.A.1
Denison, S.R.2
Calhoun, E.3
Phillips, L.A.4
Smith, D.I.5
-
5
-
-
1542351221
-
Expression of WW domain-containing oxidoreductase WOX1 in the developing murine nervous system
-
Chen ST,Chuang JI,Wang JP,Tsai MS,Li H,Chang NS.Expression of WW domain-containing oxidoreductase WOX1 in the developing murine nervous system.Neuroscience. 2004;124:831-9
-
(2004)
Neuroscience
, vol.124
, pp. 831-839
-
-
Chen, S.T.1
Chuang, J.I.2
Wang, J.P.3
Tsai, M.S.4
Li, H.5
Chang, N.S.6
-
6
-
-
12344311908
-
Light-induced retinal damage involves tyrosine 33 phosphorylation, mitochondrial and nuclear translocation of WW domain-containing oxidoreductase in vivo
-
Chen ST,Chuang JI,Cheng CL,Hsu LJ,Chang NS.Light-induced retinal damage involves tyrosine 33 phosphorylation, mitochondrial and nuclear translocation of WW domain-containing oxidoreductase in vivo.Neuroscience. 2005;130:397-407
-
(2005)
Neuroscience
, vol.130
, pp. 397-407
-
-
Chen, S.T.1
Chuang, J.I.2
Cheng, C.L.3
Hsu, L.J.4
Chang, N.S.5
-
7
-
-
3142710158
-
Down-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's disease
-
Sze CI,Su M,Pugazhenthi S,Jambal P,Hsu LJ,Heath J,Schultz L,Chang NS.Down-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's disease.J Biol Chem. 2004;279:30498-506
-
(2004)
J Biol Chem
, vol.279
, pp. 30498-30506
-
-
Sze, C.I.1
Su, M.2
Pugazhenthi, S.3
Jambal, P.4
Hsu, L.J.5
Heath, J.6
Schultz, L.7
Chang, N.S.8
-
8
-
-
23844466267
-
WOX1 is essential for UVB irradiation-induced apoptosis and down-regulated via translational blockade in UVB-induced cutaneous squamous cell carcinoma in vivo
-
Lai FJ,Cheng CL,Chen ST,Wu CH,Hsu LJ,Lee JY,Chao SC,Sheen MC,Shen CL,Chang NS,Sheu HM.WOX1 is essential for UVB irradiation-induced apoptosis and down-regulated via translational blockade in UVB-induced cutaneous squamous cell carcinoma in vivo.Clin Cancer Res. 2005;11:5769-77
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5769-5777
-
-
Lai, F.J.1
Cheng, C.L.2
Chen, S.T.3
Wu, C.H.4
Hsu, L.J.5
Lee, J.Y.6
Chao, S.C.7
Sheen, M.C.8
Shen, C.L.9
Chang, N.S.10
Sheu, H.M.11
-
9
-
-
33845879138
-
WW domain-containing oxidoreductase: a candidate tumor suppressor
-
Chang NS,Hsu LJ,Lin YS,Lai FJ,Sheu HM.WW domain-containing oxidoreductase: a candidate tumor suppressor.Trends Mol Med. 2007;13:12-22
-
(2007)
Trends Mol Med
, vol.13
, pp. 12-22
-
-
Chang, N.S.1
Hsu, L.J.2
Lin, Y.S.3
Lai, F.J.4
Sheu, H.M.5
-
11
-
-
84884228501
-
Tumor suppressor WWOX and p53 alterations and drug resistance in glioblastomas
-
Chiang MF,Chou PY,Wang WJ,Sze CI,Chang NS.Tumor suppressor WWOX and p53 alterations and drug resistance in glioblastomas.Front Oncol. 2013;3:43-43
-
(2013)
Front Oncol
, vol.3
, pp. 43
-
-
Chiang, M.F.1
Chou, P.Y.2
Wang, W.J.3
Sze, C.I.4
Chang, N.S.5
-
12
-
-
84928411218
-
-
Chen SJ, Lin PW, Tsai CC, Lin HP, Huang SS, Lai FJ, Sheu HM, Hsu LJ, Chang NS. UV irradiation/cold shock-mediated apoptosis is switched to bubbling cell death at low temperatures. Oncotarget 2015; in press
-
Chen SJ, Lin PW, Tsai CC, Lin HP, Huang SS, Lai FJ, Sheu HM, Hsu LJ, Chang NS. UV irradiation/cold shock-mediated apoptosis is switched to bubbling cell death at low temperatures. Oncotarget 2015; in press.
-
-
-
-
13
-
-
84920024627
-
WW domain-containing oxidoreductase in neuronal injury and neurological diseases
-
Chang HT,Liu CC,Chen ST,Yap YV,Chang NS,Sze CI.WW domain-containing oxidoreductase in neuronal injury and neurological diseases.Oncotarget (Focus on Aging). 2015;5:11792-9
-
(2015)
Oncotarget (Focus on Aging)
, vol.5
, pp. 11792-11799
-
-
Chang, H.T.1
Liu, C.C.2
Chen, S.T.3
Yap, Y.V.4
Chang, N.S.5
Sze, C.I.6
-
14
-
-
41549121943
-
MPP+-induced neuronal death in rats involves tyrosine 33 phosphorylation of WW domain-containing oxidoreductase WOX1
-
Lo CP,Hsu LJ,Li MY,Hsu SY,Chuang JI,Tsai MS,Lin SR,Chang NS,Chen ST.MPP+-induced neuronal death in rats involves tyrosine 33 phosphorylation of WW domain-containing oxidoreductase WOX1.Eur J Neurosci. 2008;27:1634-46
-
(2008)
Eur J Neurosci
, vol.27
, pp. 1634-1646
-
-
Lo, C.P.1
Hsu, L.J.2
Li, M.Y.3
Hsu, S.Y.4
Chuang, J.I.5
Tsai, M.S.6
Lin, S.R.7
Chang, N.S.8
Chen, S.T.9
-
15
-
-
70649087176
-
Dramatic co-activation of WWOX/WOX1 with CREB and NF-kappaB in delayed loss of small dorsal root ganglion neurons upon sciatic nerve transection in rats
-
Li MY,Lai FJ,Hsu LJ,Lo CP,Cheng CL,Lin SR,Lee MH,Chang JY,Subhan D,Tsai MS,Sze CI,Pugazhenthi S,Chang NS,Chen ST.Dramatic co-activation of WWOX/WOX1 with CREB and NF-kappaB in delayed loss of small dorsal root ganglion neurons upon sciatic nerve transection in rats.PLoS One. 2009;4:e7820-e7820
-
(2009)
PLoS One
, vol.4
, pp. 7820
-
-
Li, M.Y.1
Lai, F.J.2
Hsu, L.J.3
Lo, C.P.4
Cheng, C.L.5
Lin, S.R.6
Lee, M.H.7
Chang, J.Y.8
Subhan, D.9
Tsai, M.S.10
Sze, C.I.11
Pugazhenthi, S.12
Chang, N.S.13
Chen, S.T.14
-
16
-
-
84924256659
-
Jan 13 (Epub ahead of print)
-
(TRAPPC6AΔ) is an extracellular plaque-forming protein in the brain. Oncotarget (Focus on Aging)
-
Chang JY, Lee MH, Lin SR, Yang LY, Sun HS, Sze CI, Hong Q, Lin YS, Chou YT, Hsu LJ, Jan MS, Gong CX, Chang NS. Trafficking protein particle complex 6A delta (TRAPPC6AΔ) is an extracellular plaque-forming protein in the brain. Oncotarget (Focus on Aging) 2015; Jan 13 (Epub ahead of print). PMID: 25650666.
-
(2015)
PMID
-
-
Chang, J.Y.1
Lee, M.H.2
Lin, S.R.3
Yang, L.Y.4
Sun, H.S.5
Sze, C.I.6
Hong, Q.7
Lin, Y.S.8
Chou, Y.T.9
Hsu, L.J.10
Jan, M.S.11
Gong, C.X.12
6A delta, C.N.S.T.13
-
17
-
-
79959799455
-
TGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease
-
Lee MH,Lin SR,Chang JY,Schultz L,Heath J,Hsu LJ,Kuo YM,Hong Q,Chiang MF,Gong CX,Sze CI,Chang NS.TGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease.Cell Death Dis. 2010;1:e110-e110
-
(2010)
Cell Death Dis
, vol.1
, pp. 110
-
-
Lee, M.H.1
Lin, S.R.2
Chang, J.Y.3
Schultz, L.4
Heath, J.5
Hsu, L.J.6
Kuo, Y.M.7
Hong, Q.8
Chiang, M.F.9
Gong, C.X.10
Sze, C.I.11
Chang, N.S.12
-
18
-
-
84862108093
-
TIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53-deficient environment, and cell death
-
Chang JY,Chiang MF,Lin SR,Lee MH,He H,Chou PY,Chen SJ,Chen YA,Yang LY,Lai FJ,Hsieh CC,Hsieh TH,Sheu HM,Sze CI,Chang NS.TIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53-deficient environment, and cell death.Cell Death Dis. 2012;3:e302-e302
-
(2012)
Cell Death Dis
, vol.3
, pp. 302
-
-
Chang, J.Y.1
Chiang, M.F.2
Lin, S.R.3
Lee, M.H.4
He, H.5
Chou, P.Y.6
Chen, S.J.7
Chen, Y.A.8
Yang, L.Y.9
Lai, F.J.10
Hsieh, C.C.11
Hsieh, T.H.12
Sheu, H.M.13
Sze, C.I.14
Chang, N.S.15
-
19
-
-
84860780063
-
WW domain-containing oxidoreductase promotes neuronal differentiation via negative regulation of glycogen synthase kinase 3β
-
Wang HY,Juo LI,Lin YT,Hsiao M,Lin JT,Tsai CH,Tzeng YH,Chuang YC,Chang NS,Yang CN,Lu PJ.WW domain-containing oxidoreductase promotes neuronal differentiation via negative regulation of glycogen synthase kinase 3β.Cell Death Differ. 2012;19:1049-59
-
(2012)
Cell Death Differ
, vol.19
, pp. 1049-1059
-
-
Wang, H.Y.1
Juo, L.I.2
Lin, Y.T.3
Hsiao, M.4
Lin, J.T.5
Tsai, C.H.6
Tzeng, Y.H.7
Chuang, Y.C.8
Chang, N.S.9
Yang, C.N.10
Lu, P.J.11
-
20
-
-
0038322051
-
JNK1 physically interacts with WW domain-containing oxidoreductase (WOX1) and inhibits WOX1-mediated apoptosis
-
Chang NS,Doherty J,Ensign A.JNK1 physically interacts with WW domain-containing oxidoreductase (WOX1) and inhibits WOX1-mediated apoptosis.J Biol Chem. 2003;278:9195-202
-
(2003)
J Biol Chem
, vol.278
, pp. 9195-9202
-
-
Chang, N.S.1
Doherty, J.2
Ensign, A.3
-
21
-
-
80053012914
-
Identification of an in vivo MEK/WOX1 complex as a master switch for apoptosis in T Cell leukemia
-
Lin HP,Chang JY,Lin SR,Lee MH,Huang SS,Hsu LJ,Chang NS.Identification of an in vivo MEK/WOX1 complex as a master switch for apoptosis in T Cell leukemia.Genes Cancer. 2011;2:550-62
-
(2011)
Genes Cancer
, vol.2
, pp. 550-562
-
-
Lin, H.P.1
Chang, J.Y.2
Lin, S.R.3
Lee, M.H.4
Huang, S.S.5
Hsu, L.J.6
Chang, N.S.7
-
22
-
-
84893833543
-
The tumour suppressor gene WWOX is mutated in autosomal recessive cerebellar ataxia with epilepsy and mental retardation
-
Mallaret M,Synofzik M,Lee J,Sagum CA,Mahajnah M,Sharkia R,Drouot N,Renaud M,Klein FA,Anheim M,Tranchant C,Mignot C,Mandel JL,Bedford M,Bauer P,Salih MA,Schüle R,Schöls L,Aldaz CM,Koenig M.The tumour suppressor gene WWOX is mutated in autosomal recessive cerebellar ataxia with epilepsy and mental retardation.Brain. 2014;137:411-419
-
(2014)
Brain
, vol.137
, pp. 411-419
-
-
Mallaret, M.1
Synofzik, M.2
Lee, J.3
Sagum, C.A.4
Mahajnah, M.5
Sharkia, R.6
Drouot, N.7
Renaud, M.8
Klein, F.A.9
Anheim, M.10
Tranchant, C.11
Mignot, C.12
Mandel, J.L.13
Bedford, M.14
Bauer, P.15
Salih, M.A.16
Schüle, R.17
Schöls, L.18
Aldaz, C.M.19
Koenig, M.20
more..
-
23
-
-
84892714706
-
The supposed tumor suppressor gene WWOX is mutated in an early lethal microcephaly syndrome with epilepsy, growth retardation and retinal degeneration
-
Abdel-Salam G,Thoenes M,Afifi HH,Korber F,Swan D,Bolz HJ.The supposed tumor suppressor gene WWOX is mutated in an early lethal microcephaly syndrome with epilepsy, growth retardation and retinal degeneration.Orphanet J Rare Dis. 2014;9:12-12
-
(2014)
Orphanet J Rare Dis
, vol.9
, pp. 12
-
-
Abdel-Salam, G.1
Thoenes, M.2
Afifi, H.H.3
Korber, F.4
Swan, D.5
Bolz, H.J.6
-
24
-
-
70349690654
-
A spontaneous mutation of the Wwox gene and audiogenic seizures in rats with lethal dwarfism and epilepsy
-
Suzuki H,Katayama K,Takenaka M,Amakasu K,Saito K,Suzuki K.A spontaneous mutation of the Wwox gene and audiogenic seizures in rats with lethal dwarfism and epilepsy.Genes Brain Behav. 2009;8:650-660
-
(2009)
Genes Brain Behav
, vol.8
, pp. 650-660
-
-
Suzuki, H.1
Katayama, K.2
Takenaka, M.3
Amakasu, K.4
Saito, K.5
Suzuki, K.6
-
25
-
-
78651079527
-
Drosophila orthologue of WWOX, the chromosomal fragile site FRA16D tumour suppressor gene, functions in aerobic metabolism and regulates reactive oxygen species
-
O'Keefe LV,Colella A,Dayan S,Chen Q,Choo A,Jacob R,Price G,Venter D,Richards RI.Drosophila orthologue of WWOX, the chromosomal fragile site FRA16D tumour suppressor gene, functions in aerobic metabolism and regulates reactive oxygen species.Hum Mol Genet. 2011;20:497-509
-
(2011)
Hum Mol Genet
, vol.20
, pp. 497-509
-
-
O'Keefe, L.V.1
Colella, A.2
Dayan, S.3
Chen, Q.4
Choo, A.5
Jacob, R.6
Price, G.7
Venter, D.8
Richards, R.I.9
-
26
-
-
34247273473
-
Targeted deletion of Wwox reveals a tumor suppressor function
-
Aqeilan RI,Trapasso F,Hussain S,Costinean S,Marshall D,Pekarsky Y,Hagan JP,Zanesi N,Kaou M,Stein GS,Lian JB,Croce CM.Targeted deletion of Wwox reveals a tumor suppressor function.Proc Natl Acad Sci USA. 2007;104:3949-54
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 3949-3954
-
-
Aqeilan, R.I.1
Trapasso, F.2
Hussain, S.3
Costinean, S.4
Marshall, D.5
Pekarsky, Y.6
Hagan, J.P.7
Zanesi, N.8
Kaou, M.9
Stein, G.S.10
Lian, J.B.11
Croce, C.M.12
-
27
-
-
79551625912
-
The tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesis
-
Fu J,Qu Z,Yan P,Ishikawa C,Aqeilan RI,Rabson AB,Xiao G.The tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesis.Blood. 2011;117:1652-61
-
(2011)
Blood
, vol.117
, pp. 1652-1661
-
-
Fu, J.1
Qu, Z.2
Yan, P.3
Ishikawa, C.4
Aqeilan, R.I.5
Rabson, A.B.6
Xiao, G.7
-
28
-
-
84880047211
-
WW domain-containing oxidoreductase is involved in upregulation of matrix metalloproteinase 9 by Epstein-Barr virus latent membrane protein 2A
-
Lan YY,Wu SY,Lai HC,Chang NS,Chang FH,Tsai MH,Su IJ,Chang Y.WW domain-containing oxidoreductase is involved in upregulation of matrix metalloproteinase 9 by Epstein-Barr virus latent membrane protein 2A.Biochem Biophys Res Commun. 2013;436:672-6
-
(2013)
Biochem Biophys Res Commun
, vol.436
, pp. 672-676
-
-
Lan, Y.Y.1
Wu, S.Y.2
Lai, H.C.3
Chang, N.S.4
Chang, F.H.5
Tsai, M.H.6
Su, I.J.7
Chang, Y.8
|