TIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53-deficient environment, and cell death

Cell Death and Disease

Volumn 3, Issue 4, 2012, Pages

  Chang, J Y ^a   Chiang, M F ^b   Lin, S R ^a   Lee, M H ^a   He, H ^a   Chou, P Y ^a   Chen, S J ^a   Chen, Y A ^a   Yang, L Y ^a   Lai, F J ^c   Hsieh, C C ^c   Hsieh, T H ^a   Sheu, H M ^a   Sze, C I ^a   Chang, N S ^a,b,d,e  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c CHI MEI MEDICAL CENTER   (Taiwan)

^d NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^e State University of New York Upstate Medical University: College of Medicine   (United States)

Author keywords

p53; Smad4; TGF ; TIAF1; WOX1; WWOX

Indexed keywords

AMYLOID BETA PROTEIN; PROTEIN; PROTEIN P53; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA 1 INDUCED ANTIAPOPTOTIC FACTOR; UNCLASSIFIED DRUG; WOX1 PROTEIN; WWOX PROTEIN; APOPTOSIS REGULATORY PROTEIN; NUCLEAR PROTEIN; OXIDOREDUCTASE; STRESS ACTIVATED PROTEIN KINASE 1; TIAF1 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN; WWOX PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CELL DEATH; EXTRACELLULAR MATRIX; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; METASTASIS; MOUSE; NERVE CELL; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOLID TUMOR; STROMA; UPREGULATION; ANIMAL; APOPTOSIS; CELL LINE; CELL MOTION; CELL STRAIN COS1; CERCOPITHECUS; GENETICS; METABOLISM; NEOPLASM; NUDE MOUSE; PATHOLOGY; PROMOTER REGION;

AMYLOID BETA-PEPTIDES; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE; CELL MOVEMENT; CERCOPITHECUS AETHIOPS; COS CELLS; EXTRACELLULAR MATRIX; HUMANS; MICE; MICE, NUDE; MITOGEN-ACTIVATED PROTEIN KINASE 8; NEOPLASMS; NUCLEAR PROTEINS; OXIDOREDUCTASES; PROMOTER REGIONS, GENETIC; SMAD4 PROTEIN; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 84862108093     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2012.36     Document Type: Article

References (40)

1. Wahl SM, Wen J, Moutsopoulos N. TGF-beta: a mobile purveyor of immune privilege. Immunol Rev 2006; 213: 213-227. (Pubitemid 44401503)
2. Mantel PY, Schmidt-Weber CB. Transforming growth factor-beta: recent advances on its role in immune tolerance. Methods Mol Biol 2011; 677: 303-338.
3. Meulmeester E, Ten Dijke P. The dynamic roles of TGF-β in cancer. J Pathol 2011; 223: 205-218.
4. Tian M, Neil JR, Schiemann WP. Transforming growth factor-β and the hallmarks of cancer. Cell Signal 2011; 23: 951-962.
5. Chang NS, Mattison J, Cao H, Pratt N, Zhao Y, Lee C. Cloning and characterization of a novel transforming growth factor-β1-induced TIAF1 protein that inhibits tumor necrosis factor cytotoxicity. Biochem Biophys Res Commun 1998; 253: 743-749. (Pubitemid 29039213)
6. Khera S, Chang NS. TIAF1 participates in the transforming growth factor β1-mediated growth regulation. Ann NY Acad Sci 2003; 995: 11-21. (Pubitemid 36706610)
7. Schultz L, Khera S, Sleve D, Heath J, Chang NS. TIAF1 and p53 functionally interact in mediating apoptosis and silencing of TIAF1 abolishes nuclear translocation of serine 15-phosphorylated p53. DNA Cell Biol 2004; 23: 67-74. (Pubitemid 38130629)
8. van der Leij J, van den Berg A, Albrecht EW, Blokzijl T, Roozendaal R, Gouw AS et al. High expression of TIAF-1 in chronic kidney and liver allograft rejection and in activated T helper cells. Transplantation 2003; 75: 2076-2082. (Pubitemid 36793296)
9. Pfoertner S, Jeron A, Probst-Kepper M, Guzman CA, Hansen W, Westendorf AM et al. Signatures of human regulatory T cells: an encounter with old friends and new players. Genome Biol 2006; 7: R54.
10. Griseri P, Vos Y, Giorda R, Gimelli S, Beri S, Santamaria G et al. Complex pathogenesis of Hirschsprung's disease in a patient with hydrocephalus, vesico-ureteral reflux and a balanced translocation t(3;17)(p12;q11). Eur J Hum Genet 2009; 17: 483-490.
11. Lee MH, Lin SR, Chang JY, Schultz L, Heath J, Hsu LJ et al. TGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease. Cell Death Dis 2010; 1: e110.
12. Chang NS, Pratt N, Heath J, Schultz L, Sleve D, Carey GB et al. Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity. J Biol Chem 2001; 276: 3361-3370.
13. Chang NS, Hsu LJ, Lin YS, Lai FJ, Sheu HM. WW domain-containing oxidoreductase: a candidate tumor suppressor. Trends Mol Med 2007; 13: 12-22.
14. Chang JY, He RY, Lin HP, Hsu LJ, Lai FJ, Hong Q et al. Signaling from membrane receptors to tumor suppressor WW domain-containing oxidoreductase. Exp Biol Med 2010; 235: 796-804.
15. Lai FJ, Cheng CL, Chen ST, Wu CH, Hsu LJ, Lee JY et al. WOX1 is essential for UVB irradiation-induced apoptosis and down-regulated via translational blockade in UVB-induced cutaneous squamous cell carcinoma in vivo. Clin Cancer Res 2005; 11: 5769-5777. (Pubitemid 41170302)
16. Chang NS, Joki N, Mattison J, Dinh T, John S. Characterization of serum adhesive proteins that block tumor necrosis factor-mediated cell death. Cell Death Differ 1997; 4: 779-786. (Pubitemid 127680714)
17. Hsu LJ, Schultz L, Hong Q, Van Moer K, Heath J, Li MY et al. Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1 J Biol Chem 2009; 284: 16049-16059.
18. Bykov VJ, Selivanova G, Wiman KG. Small molecules that reactivate mutant p53 Eur J Cancer 2003; 39: 1828-1834. (Pubitemid 37311177)
19. Chang NS. Hyaluronidase activation of c-Jun N-terminal kinase is necessary for protection of L929 fibrosarcoma cells from staurosporine-mediated cell death. Biochem Biophys Res Commun 2001; 283: 278-826.
20. Hong Q, Hsu LJ, Schultz L, Pratt N, Mattison J, Chang NS. Zfra affects TNF-mediated cell death by interacting with death domain protein TRADD and negatively regulates the activation of NF-kappaB, JNK1, p53 and WOX1 during stress response. BMC Mol Biol 2007; 8: 50.
21. Di Fiore F, Sesboüé R, Michel P, Sabourin JC, Frebourg T. Molecular determinants of anti-EGFR sensitivity and resistance in metastatic colorectal cancer. Br J Cancer 2010; 103: 1765-1772.
22. Fröhlich E. Proteases in cutaneous malignant melanoma: relevance as biomarker and therapeutic target. Cell Mol Life Sci 2010; 67: 3947-3960.
23. Golubovskaya VM, Cance W. Focal adhesion kinase and p53 signal transduction pathways in cancer. Front Biosci 2010; 15: 901-912.
24. Taylor MA, Parvani JG, Schiemann WP. The pathophysiology of epithelialmesenchymal transition induced by transforming growth factor-βeta in normal and malignant mammary epithelial cells. J Mammary Gland Biol Neoplasia 2010; 15: 169-190.
25. Simpson MA, Lokeshwar VB. Hyaluronan and hyaluronidase in genitourinary tumors. Front Biosci 2008; 13: 5664-5680.
26. Perera M, Tsang CS, Distel RJ, Lacy JN, Ohno-Machado L, Ricchiuti V et al. TGF-beta1 interactome: metastasis and beyond. Cancer Genomics Proteomics 2010; 7: 217-229.
27. Kraljevic Pavelic S, Sedic M, Bosnjak H, Spaventi S, Pavelic K. Metastasis: new perspectives on an old problem. Mol Cancer 2011; 10: 22.
28. Schaller BJ, Buchfelder M. Neuroprotection in primary brain tumors: sense or nonsense? Expert Rev Neurother 2006; 6: 723-730. (Pubitemid 43961876)
29. Stern R. Association between cancer and "acid mucopolysaccharides": an old concept comes of age, finally. Semin Cancer Biol 2008; 18: 238-243.
30. Mao R, Fan Y, Mou Y, Zhang H, Fu S, Yang J. TAK1 lysine 158 is required for TGF-β-induced TRAF6-mediated Smad-independent IKK/NF-kB and JNK/AP-1 activation. Cell Signal 2011; 23: 222-227.
31. Cordray P, Satterwhite DJ. TGF-βeta induces novel Lef-1 splice variants through a Smad-independent signaling pathway. Dev Dyn 2005; 232: 969-978. (Pubitemid 40463949)
32. Droguett R, Cabello-Verrugio C, Satander C, Brandan E. TGF-βeta receptors, in a Smadindependent manner, are required for terminal skeletal muscle differentiation. Exp Cell Res 2010; 316: 2487-2503.
33. Watanabe A, Hippo Y, Taniguchi H, Iwanari H, Yashiro M, Hirakawa K et al. An opposing view on WWOX protein function as a tumor suppressor. Cancer Res 2003; 63: 8629-8633. (Pubitemid 38064037)
34. Chang NS, Schultz L, Hsu LJ, Lewis J, Su M, Sze CI. 17beta-estradiol upregulates and activates WOX1/WWOXv1 and WOX2/WWOXv2 in vitro: potential role in cancerous progression of breast and prostate to a premetastatic state in vivo. Oncogene 2005; 24: 714-723. (Pubitemid 40188576)
35. Li MY, Lai FJ, Hsu LJ, Lo CP, Cheng CL, Lin SR et al. Dramatic co-activation of WWOX/WOX1 with CREB and NF-kappaB in delayed loss of small dorsal root ganglion neurons upon sciatic nerve transection in rats. PLoS One 2009; 4: e7820.
36. Chen ST, Chuang JI, Cheng CL, Hsu LJ, Chang NS. Light-induced retinal damage involves tyrosine 33 phosphorylation, mitochondrial and nuclear translocation of WW domaincontaining oxidoreductase in vivo. Neuroscience 2005; 130: 397-407.
37. Oliveira VC, Carrara RC, Simoes DL, Saggioro FP, Carlotti CG Jr, Covas DT et al. Sudan Black B treatment reduces autofluorescence and improves resolution of in situ hybridization specific fluorescent signals of brain sections. Histol Histopathol 2010; 25: 1017-1024.
38. Sze CI, Su M, Pugazhenthi S, Jambal P, Hsu LJ, Heath J et al. Down-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's disease. J Biol Chem 2004; 279: 30498-30506. (Pubitemid 38937980)
39. Lin HP, Chang JY, Huang SS, Lin SR, Lee MH, Hsu LJ et al. Phorbol ester dissociates an in vivo MEK/WOX1 complex for switching on a novel type of apoptosis in T lymphocytes. Genes Cancer 2011; 2: 550.
40. Goyal P, Behring A, Kumar A, Siess W. STK35L1 associates with nuclear actin and regulates cell cycle and migration of endothelial cells. PLoS One 2011; 6: e16249.