Aberrant activation of atypical protein kinase C in carbon tetrachloride-induced oxidative stress provokes a disturbance of cell polarity and sealing of bile canalicular lumen

American Journal of Pathology

Volumn 185, Issue 4, 2015, Pages 958-968

  Horikoshi, Yosuke ^a,b   Kitatani, Kanae ^a   Toriumi, Kentaro ^a   Fukunishi, Nahoko ^c   Itoh, Yoshiko ^c   Nakamura, Naoya ^a   Ohno, Shigeo ^d   Matsura, Tatsuya ^b   Takekoshi, Susumu ^a  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

^c TOKAI UNIVERSITY   (Japan)

^d YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; CARBON TETRACHLORIDE; PROTEINASE ACTIVATED RECEPTOR 3; CARRIER PROTEIN; PAR-3 PROTEIN, RAT; PKC-3 PROTEIN; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; BILE; BILE CANALICULAR LUMEN; BINDING AFFINITY; CELL DISRUPTION; CELL POLARITY; CELL PROTECTION; CELL ULTRASTRUCTURE; CELLULAR STRESS RESPONSE; COMPLEX FORMATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GOLGI COMPLEX; LIVER CELL; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; TIGHT JUNCTION; ANIMAL; BIOLOGICAL MODEL; DRUG EFFECTS; ENZYMOLOGY; HUMAN; INTRAHEPATIC BILE DUCT; LIVER; METABOLISM; PATHOLOGY; ULTRASTRUCTURE; WISTAR RAT;

ANIMALS; BILE CANALICULI; CARBON TETRACHLORIDE; CARRIER PROTEINS; CELL POLARITY; ENZYME ACTIVATION; GOLGI APPARATUS; HEPATOCYTES; HUMANS; LIVER; MALE; MODELS, BIOLOGICAL; OXIDATIVE STRESS; PROTEIN KINASE C; RATS, WISTAR; TIGHT JUNCTIONS; VITAMIN E;

EID: 84925337059     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2014.12.015     Document Type: Article

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