Alternative Binding Modes Identified for Growth and Differentiation Factor-associated Serum Protein (GASP) Family Antagonism of Myostatin

Journal of Biological Chemistry

Volumn 290, Issue 12, 2015, Pages 7506-7516

  Walker, Ryan G ^a   Angerman, Elizabeth B ^a   Kattamuri, Chandramohan ^a   Lee, Yun Sil ^b   Lee, Se Jin ^b   Thompson, Thomas B ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; MUSCLE;

C-TERMINAL DOMAINS; C-TERMINAL TRUNCATION; COMPLEX FORMATIONS; LIGAND BINDING; NEGATIVE REGULATORS; SERUM PROTEINS; SOLUTION STRUCTURES; THERAPEUTIC TARGETS;

LIGANDS;

BINDING PROTEIN; GROWTH AND DIFFERENTIATION FACTOR ASSOCIATED SERUM PROTEIN 1; GROWTH AND DIFFERENTIATION FACTOR ASSOCIATED SERUM PROTEIN 2; MYOSTATIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; G PROTEIN COUPLED RECEPTOR; GASP-1 PROTEIN, MOUSE; GASP-2 PROTEIN, MOUSE; PROTEIN BINDING;

ARTICLE; BINDING AFFINITY; BINDING COMPETITION; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; GEL PERMEATION CHROMATOGRAPHY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; STOICHIOMETRY; STRUCTURE ANALYSIS; ULTRACENTRIFUGATION; X RAY CRYSTALLOGRAPHY; ANIMAL; CHO CELL LINE; CRICETULUS; HAMSTER; HEK293 CELL LINE; HUMAN; METABOLISM; MOUSE; RADIATION SCATTERING; SIZE EXCLUSION CHROMATOGRAPHY; SURFACE PLASMON RESONANCE;

ANIMALS; CARRIER PROTEINS; CHO CELLS; CHROMATOGRAPHY, GEL; CRICETINAE; CRICETULUS; HEK293 CELLS; HUMANS; MICE; MYOSTATIN; PROTEIN BINDING; RECEPTORS, G-PROTEIN-COUPLED; SCATTERING, RADIATION; SURFACE PLASMON RESONANCE; ULTRACENTRIFUGATION;

EID: 84925308018     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.624130     Document Type: Article

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