메뉴 건너뛰기




Volumn 10, Issue , 2014, Pages

Cannabinoid Receptor 2 Agonist Attenuates Pain Related Behavior in Rats with Chronic Alcohol/High Fat Diet Induced Pancreatitis

Author keywords

44 C hotplate test; Alcohol; Behavioral testing; CB2; High fat; Hyperalgesia; Ki67; Pain; Pancreas; Tissue repair

Indexed keywords

ALCOHOL DERIVATIVE; CANNABINOID 1 RECEPTOR; CANNABINOID RECEPTOR AGONIST;

EID: 84925287131     PISSN: None     EISSN: 17448069     Source Type: Journal    
DOI: 10.1186/1744-8069-10-66     Document Type: Article
Times cited : (21)

References (59)
  • 1
    • 84858076104 scopus 로고    scopus 로고
    • Unraveling the mystery of pain in chronic pancreatitis
    • Pasricha PJ: Unraveling the mystery of pain in chronic pancreatitis. Nat Rev Gastroenterol Hepatol 2012, 9:140–151.
    • (2012) Nat Rev Gastroenterol Hepatol , vol.9 , pp. 140-151
    • Pasricha, P.J.1
  • 3
    • 84883464638 scopus 로고    scopus 로고
    • Genetics of acute and chronic pancreatitis
    • Mounzer R Whitcomb DC: Genetics of acute and chronic pancreatitis. Curr Opin Gastroenterol 2013, 29:544–551.
    • (2013) Curr Opin Gastroenterol , vol.29 , pp. 544-551
    • Mounzer, R.1    Whitcomb, D.C.2
  • 6
    • 79952198989 scopus 로고    scopus 로고
    • Is lipid signaling through cannabinoid 2 receptors part of a protective system?
    • Pacher P Mechoulam R: Is lipid signaling through cannabinoid 2 receptors part of a protective system? Prog Lipid Res 2011, 50:193–211.
    • (2011) Prog Lipid Res , vol.50 , pp. 193-211
    • Pacher, P.1    Mechoulam, R.2
  • 7
    • 77952623444 scopus 로고    scopus 로고
    • CB2: A cannabinoid receptor with an identity crisis
    • Atwood BK Mackie K: CB2: A cannabinoid receptor with an identity crisis. Br J Pharmacol 2010, 160:467–479.
    • (2010) Br J Pharmacol , vol.160 , pp. 467-479
    • Atwood, B.K.1    Mackie, K.2
  • 8
    • 77957342606 scopus 로고    scopus 로고
    • Expression and function of cannabinoid receptors in mouse islets
    • Li C Bowe JE Jones PM Persaud SJ: Expression and function of cannabinoid receptors in mouse islets. Islets 2010, 2:293–302.
    • (2010) Islets , vol.2 , pp. 293-302
    • Li, C.1    Bowe, J.E.2    Jones, P.M.3    Persaud, S.J.4
  • 10
  • 11
    • 84876930960 scopus 로고    scopus 로고
    • Modulating the endocannabinoid system in human health and disease–successes and failures
    • Pacher P Kunos G: Modulating the endocannabinoid system in human health and disease–successes and failures. FEBS J 2013, 280:1918–1943.
    • (2013) FEBS J , vol.280 , pp. 1918-1943
    • Pacher, P.1    Kunos, G.2
  • 12
  • 13
    • 84887974190 scopus 로고    scopus 로고
    • Therapeutic utility of cannabinoid receptor type 2 (CB(2)) selective agonists
    • Han S Thatte J Buzard DJ Jones RM: Therapeutic utility of cannabinoid receptor type 2 (CB(2)) selective agonists. J Med Chem 2013, 56:8224–8256.
    • (2013) J Med Chem , vol.56 , pp. 8224-8256
    • Han, S.1    Thatte, J.2    Buzard, D.J.3    Jones, R.M.4
  • 14
    • 63049105150 scopus 로고    scopus 로고
    • Emerging role of the cannabinoid receptor CB2 in immune regulation: Therapeutic prospects for neuroinflammation
    • Cabral GA Griffin-Thomas L: Emerging role of the cannabinoid receptor CB2 in immune regulation: Therapeutic prospects for neuroinflammation. Expert Rev Mol Med 2009, 11:e3.
    • (2009) Expert Rev Mol Med , vol.11 , pp. e3
    • Cabral, G.A.1    Griffin-Thomas, L.2
  • 16
    • 43449130045 scopus 로고    scopus 로고
    • The cannabinoid delta-9-tetrahydrocannabinol mediates inhibition of macrophage chemotaxis to RANTES/CCL5: Linkage to the CB2 receptor
    • Raborn ES Marciano-Cabral F Buckley NE Martin BR Cabral GA: The cannabinoid delta-9-tetrahydrocannabinol mediates inhibition of macrophage chemotaxis to RANTES/CCL5: Linkage to the CB2 receptor. J Neuroimmune Pharmacol 2008, 3:117–129.
    • (2008) J Neuroimmune Pharmacol , vol.3 , pp. 117-129
    • Raborn, E.S.1    Marciano-Cabral, F.2    Buckley, N.E.3    Martin, B.R.4    Cabral, G.A.5
  • 17
    • 33845603466 scopus 로고    scopus 로고
    • Non-psychoactive CB2 cannabinoid agonists stimulate neural progenitor proliferation
    • Palazuelos J Aguado T Egia A Mechoulam R Guzman M Galve-Roperh I: Non-psychoactive CB2 cannabinoid agonists stimulate neural progenitor proliferation. FASEB J 2006, 20:2405–2407.
    • (2006) FASEB J , vol.20 , pp. 2405-2407
    • Palazuelos, J.1    Aguado, T.2    Egia, A.3    Mechoulam, R.4    Guzman, M.5    Galve-Roperh, I.6
  • 19
    • 38349119715 scopus 로고    scopus 로고
    • Cannabinoid CB2 receptors: A therapeutic target for the treatment of inflammatory and neuropathic pain
    • Guindon J Hohmann AG: Cannabinoid CB2 receptors: A therapeutic target for the treatment of inflammatory and neuropathic pain. Br J Pharmacol 2008, 153:319–334.
    • (2008) Br J Pharmacol , vol.153 , pp. 319-334
    • Guindon, J.1    Hohmann, A.G.2
  • 20
    • 0037475146 scopus 로고    scopus 로고
    • A peripheral cannabinoid mechanism suppresses spinal fos protein expression and pain behavior in a rat model of inflammation
    • Nackley AG Suplita RL 2nd Hohmann AG: A peripheral cannabinoid mechanism suppresses spinal fos protein expression and pain behavior in a rat model of inflammation. Neuroscience 2003, 117:659–670.
    • (2003) Neuroscience , vol.117 , pp. 659-670
    • Nackley, A.G.1    Suplita, R.L.2    Hohmann, A.G.3
  • 21
    • 0029865544 scopus 로고    scopus 로고
    • N-(2-hydroxyethyl) hexadecanamide is orally active in reducing edema formation and inflammatory hyperalgesia by down-modulating mast cell activation
    • Mazzari S Canella R Petrelli L Marcolongo G Leon A: N-(2-hydroxyethyl) hexadecanamide is orally active in reducing edema formation and inflammatory hyperalgesia by down-modulating mast cell activation. Eur J Pharmacol 1996, 300:227–236.
    • (1996) Eur J Pharmacol , vol.300 , pp. 227-236
    • Mazzari, S.1    Canella, R.2    Petrelli, L.3    Marcolongo, G.4    Leon, A.5
  • 22
    • 84893718412 scopus 로고    scopus 로고
    • Peripheral gating of pain signals by endogenous lipid mediators
    • Piomelli D Sasso O: Peripheral gating of pain signals by endogenous lipid mediators. Nat Neurosci 2014, 17:164–174.
    • (2014) Nat Neurosci , vol.17 , pp. 164-174
    • Piomelli, D.1    Sasso, O.2
  • 24
    • 84872387809 scopus 로고    scopus 로고
    • Activation of cannabinoid receptor 2 reduces inflammation in acute experimental pancreatitis via intra-acinar activation of p38 and MK2-dependent mechanisms
    • Michler T Storr M Kramer J Ochs S Malo A Reu S Goke B Schafer C: Activation of cannabinoid receptor 2 reduces inflammation in acute experimental pancreatitis via intra-acinar activation of p38 and MK2-dependent mechanisms. Am J Physiol Gastrointest Liver Physiol 2013, 304:G181–G192.
    • (2013) Am J Physiol Gastrointest Liver Physiol , vol.304 , pp. G181-G192
    • Michler, T.1    Storr, M.2    Kramer, J.3    Ochs, S.4    Malo, A.5    Reu, S.6    Goke, B.7    Schafer, C.8
  • 25
    • 0028177783 scopus 로고
    • Presence of pancreatic alpha-amylase, trypsinogen, and lipase immunoreactivity in normal human pancreatic ducts
    • Ohta T Terada T Nagakawa T Itoh H Tajima H Miyazaki I: Presence of pancreatic alpha-amylase, trypsinogen, and lipase immunoreactivity in normal human pancreatic ducts. Pancreas 1994, 9:382–386.
    • (1994) Pancreas , vol.9 , pp. 382-386
    • Ohta, T.1    Terada, T.2    Nagakawa, T.3    Itoh, H.4    Tajima, H.5    Miyazaki, I.6
  • 26
    • 0019850811 scopus 로고
    • Alcohol and the pancreas. I. Clinical associations and histopathology of minimal pancreatic inflammation
    • Noronha M Salgadinho A De Almeida Ferreira MJ Dreiling DA Bordalo O: Alcohol and the pancreas. I. Clinical associations and histopathology of minimal pancreatic inflammation. Am J Gastroenterol 1981, 76:114–119.
    • (1981) Am J Gastroenterol , vol.76 , pp. 114-119
    • Noronha, M.1    Salgadinho, A.2    De Almeida, F.M.J.3    Dreiling, D.A.4    Bordalo, O.5
  • 27
    • 0019846869 scopus 로고
    • Alcohol and the pancreas. II. Pancreatic morphology of advanced alcoholic pancreatitis
    • Noronha M Bordalo O Dreiling DA: Alcohol and the pancreas. II. Pancreatic morphology of advanced alcoholic pancreatitis. Am J Gastroenterol 1981, 76:120–124.
    • (1981) Am J Gastroenterol , vol.76 , pp. 120-124
    • Noronha, M.1    Bordalo, O.2    Dreiling, D.A.3
  • 28
    • 73449145253 scopus 로고    scopus 로고
    • The effect of hyperbaric oxygen on apoptosis and proliferation in severe acute pancreatitis
    • Koh SL Tan JW Muralidharan V Christophi C: The effect of hyperbaric oxygen on apoptosis and proliferation in severe acute pancreatitis. HPB (Oxford) 2009, 11:629–637.
    • (2009) HPB (Oxford) , vol.11 , pp. 629-637
    • Koh, S.L.1    Tan, J.W.2    Muralidharan, V.3    Christophi, C.4
  • 29
    • 33750616306 scopus 로고    scopus 로고
    • Establishment of animal models for three types of pancreatitis and analyses of regeneration mechanisms
    • Sakaguchi Y Inaba M Kusafuka K Okazaki K Ikehara S: Establishment of animal models for three types of pancreatitis and analyses of regeneration mechanisms. Pancreas 2006, 33:371–381.
    • (2006) Pancreas , vol.33 , pp. 371-381
    • Sakaguchi, Y.1    Inaba, M.2    Kusafuka, K.3    Okazaki, K.4    Ikehara, S.5
  • 31
  • 33
    • 0028787997 scopus 로고
    • Toward an animal model of chronic pancreatitis. Pancreatobiliary secretion in hamsters on long-term treatment with chemical inducers of cytochromes P450
    • Rutishauser SC Ali AE Jeffrey IJ Hunt LP Braganza JM: Toward an animal model of chronic pancreatitis. Pancreatobiliary secretion in hamsters on long-term treatment with chemical inducers of cytochromes P450. Int J Pancreatol 1995, 18:117–126.
    • (1995) Int J Pancreatol , vol.18 , pp. 117-126
    • Rutishauser, S.C.1    Ali, A.E.2    Jeffrey, I.J.3    Hunt, L.P.4    Braganza, J.M.5
  • 36
    • 0019802798 scopus 로고
    • The Har strains of rats: Origins and characteristics
    • Harrington GM: The Har strains of rats: Origins and characteristics. Behav Genet 1981, 11:445–468.
    • (1981) Behav Genet , vol.11 , pp. 445-468
    • Harrington, G.M.1
  • 38
    • 0025294175 scopus 로고
    • The effect of ketotifen in rodent models of anxiety and on the behavioural consequences of withdrawing from treatment with drugs of abuse
    • Costall B Kelly ME Onaivi ES Naylor RJ: The effect of ketotifen in rodent models of anxiety and on the behavioural consequences of withdrawing from treatment with drugs of abuse. Naunyn Schmiedebergs Arch Pharmacol 1990, 341:547–551.
    • (1990) Naunyn Schmiedebergs Arch Pharmacol , vol.341 , pp. 547-551
    • Costall, B.1    Kelly, M.E.2    Onaivi, E.S.3    Naylor, R.J.4
  • 39
    • 0031916179 scopus 로고    scopus 로고
    • mCPP-induced anxiety in the light–dark box in rats–a new method for screening anxiolytic activity
    • Bilkei-Gorzo A Gyertyan I Levay G: mCPP-induced anxiety in the light–dark box in rats–a new method for screening anxiolytic activity. Psychopharmacology (Berl) 1998, 136:291–298.
    • (1998) Psychopharmacology (Berl) , vol.136 , pp. 291-298
    • Bilkei-Gorzo, A.1    Gyertyan, I.2    Levay, G.3
  • 40
    • 0037274178 scopus 로고    scopus 로고
    • Effects of chronic alcohol ingestion on rat lateral/basolateral amygdala ligand-gated chloride channels
    • Botting SK Frye GD Pulido MD McCool BA: Effects of chronic alcohol ingestion on rat lateral/basolateral amygdala ligand-gated chloride channels. Ann N Y Acad Sci 2003, 985:479–480.
    • (2003) Ann N Y Acad Sci , vol.985 , pp. 479-480
    • Botting, S.K.1    Frye, G.D.2    Pulido, M.D.3    McCool, B.A.4
  • 41
    • 79955948482 scopus 로고    scopus 로고
    • Adult anxiety-related behavior of rats following consumption during late adolescence of alcohol alone and in combination with caffeine
    • Hughes RN: Adult anxiety-related behavior of rats following consumption during late adolescence of alcohol alone and in combination with caffeine. Alcohol 2011, 45:365–372.
    • (2011) Alcohol , vol.45 , pp. 365-372
    • Hughes, R.N.1
  • 42
    • 0037435920 scopus 로고    scopus 로고
    • Effects of chronic ethanol consumption on rat GABA(A) and strychnine-sensitive glycine receptors expressed by lateral/basolateral amygdala neurons
    • McCool BA Frye GD Pulido MD Botting SK: Effects of chronic ethanol consumption on rat GABA(A) and strychnine-sensitive glycine receptors expressed by lateral/basolateral amygdala neurons. Brain Res 2003, 963:165–177.
    • (2003) Brain Res , vol.963 , pp. 165-177
    • McCool, B.A.1    Frye, G.D.2    Pulido, M.D.3    Botting, S.K.4
  • 44
    • 40549088536 scopus 로고    scopus 로고
    • Pharmacological evaluation of a novel cannabinoid 2 (CB2) ligand, PF-03550096, in vitro and in vivo by using a rat model of visceral hypersensitivity
    • Kikuchi A Ohashi K Sugie Y Sugimoto H Omura H: Pharmacological evaluation of a novel cannabinoid 2 (CB2) ligand, PF-03550096, in vitro and in vivo by using a rat model of visceral hypersensitivity. J Pharmacol Sci 2008, 106:219–224.
    • (2008) J Pharmacol Sci , vol.106 , pp. 219-224
    • Kikuchi, A.1    Ohashi, K.2    Sugie, Y.3    Sugimoto, H.4    Omura, H.5
  • 48
    • 0029878661 scopus 로고    scopus 로고
    • Effects of pancreatic duct ligation and aging on acute taurocholate-induced pancreatitis. Experiments in the perfused pancreas in rats
    • Kimura W Okubo K Han I Kanai S Matsushita A Muto T Miyasaka K: Effects of pancreatic duct ligation and aging on acute taurocholate-induced pancreatitis. Experiments in the perfused pancreas in rats. Int J Pancreatol 1996, 19:117–127.
    • (1996) Int J Pancreatol , vol.19 , pp. 117-127
    • Kimura, W.1    Okubo, K.2    Han, I.3    Kanai, S.4    Matsushita, A.5    Muto, T.6    Miyasaka, K.7
  • 50
    • 0018867072 scopus 로고
    • Efficient analysis of experimental observations
    • Dixon WJ: Efficient analysis of experimental observations. Annu Rev Pharmacol Toxicol 1980, 20:441–462.
    • (1980) Annu Rev Pharmacol Toxicol , vol.20 , pp. 441-462
    • Dixon, W.J.1
  • 51
    • 0037315467 scopus 로고    scopus 로고
    • Nociception in persistent pancreatitis in rats: Effects of morphine and neuropeptide alterations
    • Vera-Portocarrero LP Lu Y Westlund KN: Nociception in persistent pancreatitis in rats: Effects of morphine and neuropeptide alterations. Anesthesiology 2003, 98:474–484.
    • (2003) Anesthesiology , vol.98 , pp. 474-484
    • Vera-Portocarrero, L.P.1    Lu, Y.2    Westlund, K.N.3
  • 52
    • 2542484528 scopus 로고    scopus 로고
    • Comparison of operant escape and innate reflex responses to nociceptive skin temperatures produced by heat and cold stimulation of rats
    • Vierck CJ Jr Kline R Wiley RG: Comparison of operant escape and innate reflex responses to nociceptive skin temperatures produced by heat and cold stimulation of rats. Behav Neurosci 2004, 118:627–635.
    • (2004) Behav Neurosci , vol.118 , pp. 627-635
    • Vierck, C.J.1    Kline, R.2    Wiley, R.G.3
  • 53
    • 0027985016 scopus 로고
    • Characterization of the foot withdrawal response to noxious radiant heat in the rat
    • Yeomans DC Proudfit HK: Characterization of the foot withdrawal response to noxious radiant heat in the rat. Pain 1994, 59:85–94.
    • (1994) Pain , vol.59 , pp. 85-94
    • Yeomans, D.C.1    Proudfit, H.K.2
  • 54
    • 0027436409 scopus 로고
    • Structure of the rat's behaviour in the hot plate test
    • Espejo EF Mir D: Structure of the rat's behaviour in the hot plate test. Behav Brain Res 1993, 56:171–176.
    • (1993) Behav Brain Res , vol.56 , pp. 171-176
    • Espejo, E.F.1    Mir, D.2
  • 55
    • 0028230970 scopus 로고
    • Effects of morphine and naloxone on behaviour in the hot plate test: An ethopharmacological study in the rat
    • Espejo EF Stinus L Cador M Mir D: Effects of morphine and naloxone on behaviour in the hot plate test: An ethopharmacological study in the rat. Psychopharmacology (Berl) 1994, 113:500–510.
    • (1994) Psychopharmacology (Berl) , vol.113 , pp. 500-510
    • Espejo, E.F.1    Stinus, L.2    Cador, M.3    Mir, D.4
  • 56
    • 0036216482 scopus 로고    scopus 로고
    • The roles of pathways in the spinal cord lateral and dorsal funiculi in signaling nociceptive somatic and visceral stimuli in rats
    • Palecek J Paleckova V Willis WD: The roles of pathways in the spinal cord lateral and dorsal funiculi in signaling nociceptive somatic and visceral stimuli in rats. Pain 2002, 96:297–307.
    • (2002) Pain , vol.96 , pp. 297-307
    • Palecek, J.1    Paleckova, V.2    Willis, W.D.3
  • 57
    • 0034781793 scopus 로고    scopus 로고
    • Changes in exploratory behavior as a measure of chronic central pain following spinal cord injury
    • Mills CD Grady JJ Hulsebosch CE: Changes in exploratory behavior as a measure of chronic central pain following spinal cord injury. J Neurotrauma 2001, 18:1091–1105.
    • (2001) J Neurotrauma , vol.18 , pp. 1091-1105
    • Mills, C.D.1    Grady, J.J.2    Hulsebosch, C.E.3
  • 58
    • 0347915543 scopus 로고    scopus 로고
    • Restoration of spontaneous exploratory behaviors with an intrathecal NMDA receptor antagonist or a PKC inhibitor in rats with acute pancreatitis
    • Zhang L Zhang X Westlund KN: Restoration of spontaneous exploratory behaviors with an intrathecal NMDA receptor antagonist or a PKC inhibitor in rats with acute pancreatitis. Pharmacol Biochem Behav 2004, 77:145–153.
    • (2004) Pharmacol Biochem Behav , vol.77 , pp. 145-153
    • Zhang, L.1    Zhang, X.2    Westlund, K.N.3
  • 59
    • 0019199013 scopus 로고
    • Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines
    • Crawley J Goodwin FK: Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines. Pharmacol Biochem Behav 1980, 13:167–170.
    • (1980) Pharmacol Biochem Behav , vol.13 , pp. 167-170
    • Crawley, J.1    Goodwin, F.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.