메뉴 건너뛰기




Volumn 267, Issue , 2015, Pages 152-164

Diffuse and persistent blood-spinal cord barrier disruption after contusive spinal cord injury rapidly recovers following intravenous infusion of bone marrow mesenchymal stem cells

Author keywords

Blood spinal cord barrier; Mesenchymal stem cell; Pericytes; Spinal cord injury

Indexed keywords

ANTIGEN; ENDOTHELIAL BARRIER ANTIGEN; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR; ENDOTHELIAL BARRIER ANTIGEN, RAT; GLIAL FIBRILLARY ACIDIC PROTEIN; MEMBRANE ANTIGEN; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR;

EID: 84925272832     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2015.03.001     Document Type: Article
Times cited : (92)

References (49)
  • 1
    • 79551646454 scopus 로고    scopus 로고
    • Astrocytes and pericytes differentially modulate blood-brain barrier characteristics during development and hypoxic insult
    • Al Ahmad A., Taboada C.B., Gassmann M., Ogunshola O.O. Astrocytes and pericytes differentially modulate blood-brain barrier characteristics during development and hypoxic insult. J. Cereb. Blood Flow Metab. 2011, 31(2):693-705.
    • (2011) J. Cereb. Blood Flow Metab. , vol.31 , Issue.2 , pp. 693-705
    • Al Ahmad, A.1    Taboada, C.B.2    Gassmann, M.3    Ogunshola, O.O.4
  • 3
    • 80051551970 scopus 로고    scopus 로고
    • The blood-spinal cord barrier: morphology and clinical implications
    • Bartanusz V., Jezova D., Alajajian B., Digicaylioglu M. The blood-spinal cord barrier: morphology and clinical implications. Ann. Neurol. 2011, 70(2):194-206.
    • (2011) Ann. Neurol. , vol.70 , Issue.2 , pp. 194-206
    • Bartanusz, V.1    Jezova, D.2    Alajajian, B.3    Digicaylioglu, M.4
  • 4
    • 0028919411 scopus 로고
    • A sensitive and reliable locomotor rating scale for open field testing in rats
    • Basso D.M., Beattie M.S., Bresnahan J.C. A sensitive and reliable locomotor rating scale for open field testing in rats. J. Neurotrauma 1995, 12(1):1-21.
    • (1995) J. Neurotrauma , vol.12 , Issue.1 , pp. 1-21
    • Basso, D.M.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 5
    • 77249125330 scopus 로고    scopus 로고
    • Quantitative analysis of cellular inflammation after traumatic spinal cord injury: evidence for a multiphasic inflammatory response in the acute to chronic environment
    • Beck K.D., Nguyen H.X., Galvan M.D., Salazar D.L., Woodruff T.M., Anderson A.J. Quantitative analysis of cellular inflammation after traumatic spinal cord injury: evidence for a multiphasic inflammatory response in the acute to chronic environment. Brain 2010, 133(Pt 2):433-447.
    • (2010) Brain , vol.133 , pp. 433-447
    • Beck, K.D.1    Nguyen, H.X.2    Galvan, M.D.3    Salazar, D.L.4    Woodruff, T.M.5    Anderson, A.J.6
  • 6
    • 84893463772 scopus 로고    scopus 로고
    • Engraftment of human mesenchymal stem cells in a rat photothrombotic cerebral infarction model: comparison of intra-arterial and intravenous infusion using MRI and histological analysis
    • Byun J.S., Kwak B.K., Kim J.K., Jung J., Ha B.C., Park S. Engraftment of human mesenchymal stem cells in a rat photothrombotic cerebral infarction model: comparison of intra-arterial and intravenous infusion using MRI and histological analysis. J. Korean Neurosurg. Soc. 2013, 54(6):467-476.
    • (2013) J. Korean Neurosurg. Soc. , vol.54 , Issue.6 , pp. 467-476
    • Byun, J.S.1    Kwak, B.K.2    Kim, J.K.3    Jung, J.4    Ha, B.C.5    Park, S.6
  • 7
    • 0034125067 scopus 로고    scopus 로고
    • Molecular basis of angiogenesis. Role of VEGF and VE-cadherin
    • (discussion 262-264)
    • Carmeliet P., Collen D. Molecular basis of angiogenesis. Role of VEGF and VE-cadherin. Ann. N. Y. Acad. Sci. 2000, 902:249-262. (discussion 262-264).
    • (2000) Ann. N. Y. Acad. Sci. , vol.902 , pp. 249-262
    • Carmeliet, P.1    Collen, D.2
  • 8
    • 64949107710 scopus 로고    scopus 로고
    • Blood-spinal cord barrier permeability in experimental spinal cord injury: dynamic contrast-enhanced MRI
    • Cohen D.M., Patel C.B., Ahobila-Vajjula P., Sundberg L.M., Chacko T., Liu S.J., Narayana P.A. Blood-spinal cord barrier permeability in experimental spinal cord injury: dynamic contrast-enhanced MRI. NMR Biomed. 2009, 22(3):332-341.
    • (2009) NMR Biomed. , vol.22 , Issue.3 , pp. 332-341
    • Cohen, D.M.1    Patel, C.B.2    Ahobila-Vajjula, P.3    Sundberg, L.M.4    Chacko, T.5    Liu, S.J.6    Narayana, P.A.7
  • 10
    • 78649487239 scopus 로고    scopus 로고
    • Pericytes are required for blood-brain barrier integrity during embryogenesis
    • Daneman R., Zhou L., Kebede A.A., Barres B.A. Pericytes are required for blood-brain barrier integrity during embryogenesis. Nature 2010, 468(7323):562-566.
    • (2010) Nature , vol.468 , Issue.7323 , pp. 562-566
    • Daneman, R.1    Zhou, L.2    Kebede, A.A.3    Barres, B.A.4
  • 12
    • 84896381322 scopus 로고    scopus 로고
    • Characterization of vascular disruption and blood-spinal cord barrier permeability following traumatic spinal cord injury
    • Figley S.A., Khosravi R., Legasto J.M., Tseng Y.F., Fehlings M.G. Characterization of vascular disruption and blood-spinal cord barrier permeability following traumatic spinal cord injury. J. Neurotrauma 2014, 31(6):541-552.
    • (2014) J. Neurotrauma , vol.31 , Issue.6 , pp. 541-552
    • Figley, S.A.1    Khosravi, R.2    Legasto, J.M.3    Tseng, Y.F.4    Fehlings, M.G.5
  • 13
    • 0035010796 scopus 로고    scopus 로고
    • The dynamic in vivo distribution of bone marrow-derived mesenchymal stem cells after infusion
    • Gao J., Dennis J.E., Muzic R.F., Lundberg M., Caplan A.I. The dynamic in vivo distribution of bone marrow-derived mesenchymal stem cells after infusion. Cells Tissues Organs 2001, 169(1):12-20.
    • (2001) Cells Tissues Organs , vol.169 , Issue.1 , pp. 12-20
    • Gao, J.1    Dennis, J.E.2    Muzic, R.F.3    Lundberg, M.4    Caplan, A.I.5
  • 14
    • 0034730458 scopus 로고    scopus 로고
    • Immunological targeting of the endothelial barrier antigen (EBA) in vivo leads to opening of the blood-brain barrier
    • Ghabriel M.N., Zhu C., Hermanis G., Allt G. Immunological targeting of the endothelial barrier antigen (EBA) in vivo leads to opening of the blood-brain barrier. Brain Res. 2000, 878(1-2):127-135.
    • (2000) Brain Res. , vol.878 , Issue.1-2 , pp. 127-135
    • Ghabriel, M.N.1    Zhu, C.2    Hermanis, G.3    Allt, G.4
  • 16
    • 78049253786 scopus 로고    scopus 로고
    • Pericyte-mediated regulation of capillary diameter: a component of neurovascular coupling in health and disease
    • (pii: 5)
    • Hamilton N.B., Attwell D., Hall C.N. Pericyte-mediated regulation of capillary diameter: a component of neurovascular coupling in health and disease. Front. Neuroenerg. 2010, 2. (pii: 5). 10.3389/fnene.2010.00005.
    • (2010) Front. Neuroenerg. , vol.2
    • Hamilton, N.B.1    Attwell, D.2    Hall, C.N.3
  • 18
    • 0030560761 scopus 로고    scopus 로고
    • A quantitative spatial analysis of the blood-spinal cord barrier. II. Permeability after intraspinal fetal transplantation
    • Horner P.J., Popovich P.G., Mullin B.B., Stokes B.T. A quantitative spatial analysis of the blood-spinal cord barrier. II. Permeability after intraspinal fetal transplantation. Exp. Neurol. 1996, 142(2):226-243.
    • (1996) Exp. Neurol. , vol.142 , Issue.2 , pp. 226-243
    • Horner, P.J.1    Popovich, P.G.2    Mullin, B.B.3    Stokes, B.T.4
  • 19
    • 7444243375 scopus 로고    scopus 로고
    • Correlation of injury severity and tissue Evans blue content, lipid peroxidation and clinical evaluation in acute spinal cord injury in rats
    • Kaptanoglu E., Okutan O., Akbiyik F., Solaroglu I., Kilinc A., Beskonakli E. Correlation of injury severity and tissue Evans blue content, lipid peroxidation and clinical evaluation in acute spinal cord injury in rats. J. Clin. Neurosci. 2004, 11(8):879-885.
    • (2004) J. Clin. Neurosci. , vol.11 , Issue.8 , pp. 879-885
    • Kaptanoglu, E.1    Okutan, O.2    Akbiyik, F.3    Solaroglu, I.4    Kilinc, A.5    Beskonakli, E.6
  • 21
    • 77954323926 scopus 로고    scopus 로고
    • Emerson M, Altman DG; NC3Rs Reporting Guidelines Working Group. Animal research: reporting in vivo experiments: the ARRIVE guidelines
    • Kilkenny C., Browne W., Cuthill I.C. Emerson M, Altman DG; NC3Rs Reporting Guidelines Working Group. Animal research: reporting in vivo experiments: the ARRIVE guidelines. J. Gene Med. 2010, 12(7):561-563.
    • (2010) J. Gene Med. , vol.12 , Issue.7 , pp. 561-563
    • Kilkenny, C.1    Browne, W.2    Cuthill, I.C.3
  • 24
    • 67649171661 scopus 로고    scopus 로고
    • Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6
    • Lee R.H., Pulin A.A., Seo M.J., Kota D.J., Ylostalo J., Larson B.L., Semprun-Prieto L., Delafontaine P., Prockop D.J. Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6. Cell Stem Cell 2009, 5(1):54-63.
    • (2009) Cell Stem Cell , vol.5 , Issue.1 , pp. 54-63
    • Lee, R.H.1    Pulin, A.A.2    Seo, M.J.3    Kota, D.J.4    Ylostalo, J.5    Larson, B.L.6    Semprun-Prieto, L.7    Delafontaine, P.8    Prockop, D.J.9
  • 25
    • 84905221020 scopus 로고    scopus 로고
    • Minimum information about a spinal cord injury experiment: a proposed reporting standard for spinal cord injury experiments
    • MIASCI Consortium
    • Lemmon V.P., Ferguson A.R., Popovich P.G., Xu X.M., Snow D.M., Igarashi M., Beattie C.E., Bixby J.L. Minimum information about a spinal cord injury experiment: a proposed reporting standard for spinal cord injury experiments. J. Neurotrauma 2014, 31(15):1354-1361. MIASCI Consortium.
    • (2014) J. Neurotrauma , vol.31 , Issue.15 , pp. 1354-1361
    • Lemmon, V.P.1    Ferguson, A.R.2    Popovich, P.G.3    Xu, X.M.4    Snow, D.M.5    Igarashi, M.6    Beattie, C.E.7    Bixby, J.L.8
  • 26
    • 0034716957 scopus 로고    scopus 로고
    • Quantitative assessment of the normal cerebral microvasculature by endothelial barrier antigen (EBA) immunohistochemistry: application to focal cerebral ischemia
    • Lin B., Ginsberg M.D. Quantitative assessment of the normal cerebral microvasculature by endothelial barrier antigen (EBA) immunohistochemistry: application to focal cerebral ischemia. Brain Res. 2000, 865(2):237-244.
    • (2000) Brain Res. , vol.865 , Issue.2 , pp. 237-244
    • Lin, B.1    Ginsberg, M.D.2
  • 29
    • 0024515595 scopus 로고
    • Distribution and time course of protein extravasation in the rat spinal cord after contusive injury
    • Noble L.J., Wrathall J.R. Distribution and time course of protein extravasation in the rat spinal cord after contusive injury. Brain Res. 1989, 482:57-66.
    • (1989) Brain Res. , vol.482 , pp. 57-66
    • Noble, L.J.1    Wrathall, J.R.2
  • 31
    • 84924908576 scopus 로고    scopus 로고
    • Intraperitoneal and intravenous deliveries are not comparable in terms of drug efficacy and cell distribution in neonatal mice with hypoxia-ischemia
    • Ohshima M., Taguchi A., Tsuda H., Sato Y., Yamahara K., Harada-Shiba M., Miyazato M., Ikeda T., Iida H., Tsuji M. Intraperitoneal and intravenous deliveries are not comparable in terms of drug efficacy and cell distribution in neonatal mice with hypoxia-ischemia. Brain Dev. 2015, 37(4):376-386.
    • (2015) Brain Dev. , vol.37 , Issue.4 , pp. 376-386
    • Ohshima, M.1    Taguchi, A.2    Tsuda, H.3    Sato, Y.4    Yamahara, K.5    Harada-Shiba, M.6    Miyazato, M.7    Ikeda, T.8    Iida, H.9    Tsuji, M.10
  • 32
    • 77953618096 scopus 로고    scopus 로고
    • Intravenous administration of mesenchymal stem cells derived from bone marrow after contusive spinal cord injury improves functional outcome
    • Osaka M., Honmou O., Murakami T., Nonaka T., Houkin K., Hamada H., Kocsis J.D. Intravenous administration of mesenchymal stem cells derived from bone marrow after contusive spinal cord injury improves functional outcome. Brain Res. 2010, 1343:226-235.
    • (2010) Brain Res. , vol.1343 , pp. 226-235
    • Osaka, M.1    Honmou, O.2    Murakami, T.3    Nonaka, T.4    Houkin, K.5    Hamada, H.6    Kocsis, J.D.7
  • 33
    • 0030560684 scopus 로고    scopus 로고
    • A quantitative spatial analysis of the blood-spinal cord barrier. I. Permeability changes after experimental spinal contusion injury
    • Popovich P.G., Horner P.J., Mullin B.B., Stokes B.T. A quantitative spatial analysis of the blood-spinal cord barrier. I. Permeability changes after experimental spinal contusion injury. Exp. Neurol. 1996, 142(2):258-275.
    • (1996) Exp. Neurol. , vol.142 , Issue.2 , pp. 258-275
    • Popovich, P.G.1    Horner, P.J.2    Mullin, B.B.3    Stokes, B.T.4
  • 34
    • 84862638483 scopus 로고    scopus 로고
    • Mesenchymal stem cell graft improves recovery after spinal cord injury in adult rats through neurotrophic and pro-angiogenic actions
    • Quertainmont R., Cantinieaux D., Botman O., Sid S., Schoenen J., Franzen R. Mesenchymal stem cell graft improves recovery after spinal cord injury in adult rats through neurotrophic and pro-angiogenic actions. PLoS One 2012, 7(6):e39500.
    • (2012) PLoS One , vol.7 , Issue.6 , pp. e39500
    • Quertainmont, R.1    Cantinieaux, D.2    Botman, O.3    Sid, S.4    Schoenen, J.5    Franzen, R.6
  • 36
    • 84874050885 scopus 로고    scopus 로고
    • Interactions of apoptotic cells with macrophages in radiation-induced bystander signaling
    • Rastogi S., Boylan M., Wright E.G., Coates P.J. Interactions of apoptotic cells with macrophages in radiation-induced bystander signaling. Radiat. Res. 2013, 179(2):135-145.
    • (2013) Radiat. Res. , vol.179 , Issue.2 , pp. 135-145
    • Rastogi, S.1    Boylan, M.2    Wright, E.G.3    Coates, P.J.4
  • 37
    • 80053284296 scopus 로고    scopus 로고
    • Action at a distance: systemically administered adult stem/progenitor cells (MSCs) reduce inflammatory damage to the cornea without engraftment and primarily by secretion of TNF-α stimulated gene/protein 6
    • Roddy G.W., Oh J.Y., Lee R.H., Bartosh T.J., Ylostalo J., Coble K., Rosa R.H., Prockop D.J. Action at a distance: systemically administered adult stem/progenitor cells (MSCs) reduce inflammatory damage to the cornea without engraftment and primarily by secretion of TNF-α stimulated gene/protein 6. Stem Cells 2011, 29(10):1572-1579.
    • (2011) Stem Cells , vol.29 , Issue.10 , pp. 1572-1579
    • Roddy, G.W.1    Oh, J.Y.2    Lee, R.H.3    Bartosh, T.J.4    Ylostalo, J.5    Coble, K.6    Rosa, R.H.7    Prockop, D.J.8
  • 39
    • 39749099817 scopus 로고    scopus 로고
    • Dilution of irradiated cell conditioned medium and the bystander effect
    • Ryan L.A., Smith R.W., Seymour C.B., Mothersill C.E. Dilution of irradiated cell conditioned medium and the bystander effect. Radiat. Res. 2008, 169(2):188-196.
    • (2008) Radiat. Res. , vol.169 , Issue.2 , pp. 188-196
    • Ryan, L.A.1    Smith, R.W.2    Seymour, C.B.3    Mothersill, C.E.4
  • 40
    • 72449122797 scopus 로고    scopus 로고
    • BDNF-hypersecreting human mesenchymal stem cells promote functional recovery, axonal sprouting, and protection of corticospinal neurons after spinal cord injury
    • Sasaki M., Radtke C., Tan A.M., Zhao P., Hamada H., Houkin K., Honmou O., Kocsis J.D. BDNF-hypersecreting human mesenchymal stem cells promote functional recovery, axonal sprouting, and protection of corticospinal neurons after spinal cord injury. J. Neurosci. 2009, 29(47):14932-14941.
    • (2009) J. Neurosci. , vol.29 , Issue.47 , pp. 14932-14941
    • Sasaki, M.1    Radtke, C.2    Tan, A.M.3    Zhao, P.4    Hamada, H.5    Houkin, K.6    Honmou, O.7    Kocsis, J.D.8
  • 42
    • 84883261127 scopus 로고    scopus 로고
    • Endothelial Von Willebrand factor promotes blood-brain barrier flexibility and provides protection from hypoxia and seizures in mice
    • Suidan G.L., Brill A., De Meyer S.F., Voorhees J.R., Cifuni S.M., Cabral J.E., Wagner D.D. Endothelial Von Willebrand factor promotes blood-brain barrier flexibility and provides protection from hypoxia and seizures in mice. Arterioscler. Thromb. Vasc. Biol. 2013, 33(9):2112-2120.
    • (2013) Arterioscler. Thromb. Vasc. Biol. , vol.33 , Issue.9 , pp. 2112-2120
    • Suidan, G.L.1    Brill, A.2    De Meyer, S.F.3    Voorhees, J.R.4    Cifuni, S.M.5    Cabral, J.E.6    Wagner, D.D.7
  • 43
    • 59749103836 scopus 로고    scopus 로고
    • Therapeutic benefits of angiogenetic gene-modified human mesenchymal stem cells after cerebral ischemia
    • Toyama K., Honmou O., Harada K., Suzuki J., Houkin K., Hamada H., Kocsis J.D. Therapeutic benefits of angiogenetic gene-modified human mesenchymal stem cells after cerebral ischemia. Exp. Neurol. 2009, 216(1):47-55.
    • (2009) Exp. Neurol. , vol.216 , Issue.1 , pp. 47-55
    • Toyama, K.1    Honmou, O.2    Harada, K.3    Suzuki, J.4    Houkin, K.5    Hamada, H.6    Kocsis, J.D.7
  • 45
    • 0141705210 scopus 로고    scopus 로고
    • Blood-spinal cord barrier after spinal cord injury: relation to revascularization and wound healing
    • Whetstone W.D., Hsu J.Y., Eisenberg M., Werb Z., Noble-Haeusslein L.J. Blood-spinal cord barrier after spinal cord injury: relation to revascularization and wound healing. J. Neurosci. Res. 2003, 74(2):227-239.
    • (2003) J. Neurosci. Res. , vol.74 , Issue.2 , pp. 227-239
    • Whetstone, W.D.1    Hsu, J.Y.2    Eisenberg, M.3    Werb, Z.4    Noble-Haeusslein, L.J.5
  • 46
    • 80055014830 scopus 로고    scopus 로고
    • Central nervous system pericytes in health and disease
    • Winkler E.A., Bell R.D., Zlokovic B.V. Central nervous system pericytes in health and disease. Nat. Neurosci. 2011, 14(11):1398-1405.
    • (2011) Nat. Neurosci. , vol.14 , Issue.11 , pp. 1398-1405
    • Winkler, E.A.1    Bell, R.D.2    Zlokovic, B.V.3
  • 47
    • 84862867271 scopus 로고    scopus 로고
    • Exosome-mediated transfer of miR-133b from multipotent mesenchymal stromal cells to neural cells contributes to neurite outgrowth
    • Xin H., Li Y., Buller B., Katakowski M., Zhang Y., Wang X., Shang X., Zhang Z.G., Chopp M. Exosome-mediated transfer of miR-133b from multipotent mesenchymal stromal cells to neural cells contributes to neurite outgrowth. Stem Cells 2012, 30(7):1556-1564.
    • (2012) Stem Cells , vol.30 , Issue.7 , pp. 1556-1564
    • Xin, H.1    Li, Y.2    Buller, B.3    Katakowski, M.4    Zhang, Y.5    Wang, X.6    Shang, X.7    Zhang, Z.G.8    Chopp, M.9
  • 48
    • 84883382523 scopus 로고    scopus 로고
    • MiR-133b promotes neural plasticity and functional recovery after treatment of stroke with multipotent mesenchymal stromal cells in rats via transfer of exosome-enriched extracellular particles
    • Xin H., Li Y., Liu Z., Wang X., Shang X., Cui Y., Zhang Z.G., Chopp M. MiR-133b promotes neural plasticity and functional recovery after treatment of stroke with multipotent mesenchymal stromal cells in rats via transfer of exosome-enriched extracellular particles. Stem Cells 2013, 31(12):2737-2746.
    • (2013) Stem Cells , vol.31 , Issue.12 , pp. 2737-2746
    • Xin, H.1    Li, Y.2    Liu, Z.3    Wang, X.4    Shang, X.5    Cui, Y.6    Zhang, Z.G.7    Chopp, M.8
  • 49
    • 79952068809 scopus 로고    scopus 로고
    • Selectin-mediated recruitment of bone marrow stromal cells in the postischemic cerebral microvasculature
    • Yilmaz G., Vital S., Yilmaz C.E., Stokes K.Y., Alexander J.S., Granger D.N. Selectin-mediated recruitment of bone marrow stromal cells in the postischemic cerebral microvasculature. Stroke 2011, 42(3):806-811.
    • (2011) Stroke , vol.42 , Issue.3 , pp. 806-811
    • Yilmaz, G.1    Vital, S.2    Yilmaz, C.E.3    Stokes, K.Y.4    Alexander, J.S.5    Granger, D.N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.