Nuclear expression of histone deacetylases and their histone modifications predicts clinical outcome in colorectal cancer

Histopathology

Volumn 66, Issue 2, 2015, Pages 270-282

  Benard, Anne ^a   Goossens Beumer, Inès J ^a   Van Hoesel, Anneke Q ^a   Horati, Hamed ^a   de Graaf, Wouter ^a   Putter, Hein ^a   Zeestraten, Eliane C M ^a   Liefers, Gerrit Jan ^a   Van de Velde, Cornelis J H ^a   Kuppen, Peter J K ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Clinical outcome; Colorectal cancer; Epigenetic regulation; Histone deacetylases; Histone modifications

Indexed keywords

HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE H3; HISTONE H3K56AC; HISTONE H4; HISTONE H4K16AC; SIRTUIN 1; UNCLASSIFIED DRUG; HISTONE; HISTONE DEACETYLASE; TUMOR MARKER;

ADULT; AGED; ARTICLE; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE SPECIFIC SURVIVAL; EPIGENETICS; FEMALE; FOLLOW UP; GENE EXPRESSION; HISTONE MODIFICATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LOCAL RECURRENCE FREE SURVIVAL; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PRIORITY JOURNAL; RECURRENCE FREE SURVIVAL; RETROSPECTIVE STUDY; TISSUE MICROARRAY; TUMOR RECURRENCE; BIOSYNTHESIS; CELL NUCLEUS; COLORECTAL TUMOR; GENETIC EPIGENESIS; GENETICS; KAPLAN MEIER METHOD; METABOLISM; MIDDLE AGED; MORTALITY; PATHOLOGY; PROPORTIONAL HAZARDS MODEL;

AGED; CELL NUCLEUS; COLORECTAL NEOPLASMS; EPIGENESIS, GENETIC; FEMALE; HISTONE DEACETYLASES; HISTONES; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS; TISSUE ARRAY ANALYSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 84925258133     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/his.12534     Document Type: Article

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