Toxicity of Eosinophil MBP Is Repressed by Intracellular Crystallization and Promoted by Extracellular Aggregation

Molecular Cell

Volumn 57, Issue 6, 2015, Pages 1011-1021

  Soragni, Alice ^a,b,c   Yousefi, Shida ^b   Stoeckle, Christina ^b   Soriaga, Angela B ^a   Sawaya, Michael R ^a   Kozlowski, Evelyne ^b   Schmid, Inès ^b   Radonjic Hoesli, Susanne ^b   Boutet, Sebastien ^d   Williams, Garth J ^d   Messerschmidt, Marc ^e   Seibert, M Marvin ^d   Cascio, Duilio ^a   Zatsepin, Nadia A ^f   Burghammer, Manfred ^g,h   Riekel, Christian ^g   Colletier, Jacques Philippe ^i,j   Riek, Roland ^c   Eisenberg, David S ^a   Simon, Hans Uwe ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF BERN   (Switzerland)

^c ETH ZURICH   (Switzerland)

^d SLAC NATIONAL ACCELERATOR LABORATORY   (United States)

^e NATIONAL SCIENCE FOUNDATION   (United States)

^f ARIZONA STATE UNIVERSITY   (United States)

^g EUROPEAN SYNCHROTRON RADIATION FACILITY   (France)

^h GHENT UNIVERSITY   (Belgium)

ⁱ INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^j CEA GRENOBLE   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; MAJOR BASIC PROTEIN; NANOCRYSTAL; TOXIN; DENND4A PROTEIN, HUMAN; DNA BINDING PROTEIN; NANOPARTICLE;

ACIDIFICATION; AMYLOID PLAQUE; ANIMAL EXPERIMENT; ARTICLE; BACTERIAL MEMBRANE; CELL ACTIVATION; CELL AGGREGATION; CELL DAMAGE; CONTROLLED STUDY; CRYSTALLIZATION; CYTOTOXICITY; ELECTRON; EOSINOPHIL; EOSINOPHILIA; EPITHELIUM CELL; EX VIVO STUDY; FEEDBACK SYSTEM; HOST CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MEMBRANE DAMAGE; MOUSE; NONHUMAN; PATHOGENESIS; PROTEIN AGGREGATION; PROTEIN STRUCTURE; TISSUE INJURY; X RAY; ANIMAL; ATOPIC DERMATITIS; C57BL MOUSE; CELL DEATH; CELL LINE; CELL MEMBRANE; CELLULITIS; CHEMISTRY; DRUG EFFECTS; ESCHERICHIA COLI; HOST PATHOGEN INTERACTION; INNATE IMMUNITY; METABOLISM; PATHOLOGY; PHYSIOLOGY; SECRETORY VESICLE; SKIN;

ANIMALS; CELL DEATH; CELL LINE; CELL MEMBRANE; CELLULITIS; DERMATITIS, ATOPIC; DNA-BINDING PROTEINS; EOSINOPHILIA; EOSINOPHILS; EPITHELIAL CELLS; ESCHERICHIA COLI; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, INNATE; MICE, INBRED C57BL; NANOPARTICLES; SECRETORY VESICLES; SKIN;

EID: 84925248498     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2015.01.026     Document Type: Article

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