Metabolic engineering of Escherichia coli for enhanced arginine biosynthesis

Microbial Cell Factories

Volumn 14, Issue 1, 2015, Pages

  Ginesy, Mireille ^a   Belotserkovsky, Jaroslav ^b   Enman, Josefine ^a   Isaksson, Leif ^b   Rova, Ulrika ^a  

^a LULEÅ UNIVERSITY OF TECHNOLOGY   (Sweden)

^b STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Escherichia coli; Fermentation; L arginine; Metabolic engineering

Indexed keywords

ACETIC ACID; ARGININE; ARGININE DECARBOXYLASE; ARGININE RESPONSIVE REPRESSOR PROTEIN; BACTERIAL PROTEIN; CARBON; GLUCOSE; GLUTAMIC ACID; NITROGEN; ORNITHINE DECARBOXYLASE; RIBOSOME RNA; UNCLASSIFIED DRUG; CARBOXYLYASE; ESCHERICHIA COLI PROTEIN;

ACETYLATION; AMINO ACID SYNTHESIS; ARTICLE; BACTERIAL GROWTH; BIOASSAY; BIOREACTOR; BIOSENSOR; BIOSYNTHESIS; CELL GROWTH; CONTROLLED STUDY; DNA MODIFICATION; ESCHERICHIA COLI; FERMENTATION; GENE DOSAGE; GENETIC MANIPULATION; GLUCOSE INTAKE; GLUCOSE TRANSPORT; HOMOLOGOUS RECOMBINATION; METABOLIC ENGINEERING; NEGATIVE FEEDBACK; NONHUMAN; GENE INACTIVATION; GENETICS; METABOLISM; PLASMID;

ADIA; ESCHERICHIA COLI;

ARGININE; CARBOXY-LYASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE KNOCKOUT TECHNIQUES; GLUTAMIC ACID; METABOLIC ENGINEERING; ORNITHINE DECARBOXYLASE; PLASMIDS;

EID: 84925218937     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/s12934-015-0211-y     Document Type: Article

References (40)

1. Loscalzo J. L-arginine and atherothrombosis. J Nutr. 2004;134(10 Suppl):2798S-800. discussion 2818S-2819S.
2. Ohlund J, Nasholm T. Low nitrogen losses with a new source of nitrogen for cultivation of conifer seedlings. Environ Sci Technol. 2002;36(22):4854-9.
3. Kinoshita S, Udaka S, Shimono M. Studies on the amino acid fermentation part I. Production of L-glutamic acid by various microorganisms. J Gen Appl Microbiol. 1957;3(3):193-205.
4. Hermann T. Industrial production of amino acids by coryneform bacteria. J Biotechnol. 2003;104(1-3):155-72.
5. Utagawa T. Production of arginine by fermentation. J Nutr. 2004;134(10 Suppl):2854S-7. discussion 2895S.
6. Park SH, Kim HU, Kim TY, Park JS, Kim S, Lee SY. Metabolic engineering of Corynebacterium glutamicum for L-arginine production. Nat Commun. 2014;5:4618.
7. Shin J, Lee S. Metabolic engineering of microorganisms for the production of L-arginine and its derivatives. Microb Cell Fact. 2014;13(1):166.
8. Gusyatiner MM, Leonova TV, Ptitsyn LR, Yampolskaya TA. L-Arginine Producing Escherichia Coli and Method of Producing L-Arginine. 2005.
9. Rostova YG, Voroshilova EB, Gusyatiner MM. Method for Producing an L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family Having Attenuated Expression of Genes Encoding a Lysine/Arginine/ Ornithine Transporter. 2013.
10. Kiryukhin MY, Gusyatiner MM. Method for Producing an L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family. 2013.
11. Vyas S, Maas WK. Feedback inhibition of acetylglutamate synthetase by arginine in Escherichia coli. Arch Biochem Biophys. 1963;100(3):542-6.
12. Maas WK. The arginine repressor of Escherichia coli. Microbiol Rev. 1994;58(4):631-40.
13. Celis RT. Repression and activation of arginine transport genes in Escherichia coli K 12 by the ArgP protein. J Mol Biol. 1999;294(5):1087-95.
14. Nandineni MR, Gowrishankar J. Evidence for an arginine exporter encoded by yggA (argO) that is regulated by the LysR-type transcriptional regulator ArgP in Escherichia coli. J Bacteriol. 2004;186(11):3539-46.
15. Laishram RS, Gowrishankar J. Environmental regulation operating at the promoter clearance step of bacterial transcription. Genes Dev. 2007;21(10):1258-72.
16. Peeters E, Nguyen Le Minh P, Foulquie-Moreno M, Charlier D. Competitive activation of the Escherichia coli argO gene coding for an arginine exporter by the transcriptional regulators Lrp and ArgP. Mol Microbiol. 2009;74(6):1513-26.
17. Marbaniang CN, Gowrishankar J. Role of ArgP (IciA) in lysine-mediated repression in Escherichia coli. J Bacteriol. 2011;193(21):5985-96.
18. Applebaum D, Sabo DL, Fischer EH, Morris DR. Biodegradative ornithine decarboxylase of Escherichia coli. Purification, properties, and pyridoxal 5'-phosphate binding site. Biochemistry. 1975;14(16):3675-81.
19. Applebaum DM, Dunlap JC, Morris DR. Comparison of the biosynthetic and biodegradative ornithine decarboxylases of Escherichia coli. Biochemistry. 1977;16(8):1580-4.
20. Kubota K, Onoda T, Kamijo H, Yoshinaga F, Okumura S. Micorbial production of L-arginine; I. Production of L-ariginine by mutants of glutamic acid-producing bacteria. J Gen Appl Microbiol. 1973;19(5):339-52.
21. Schwartz JH, Maas WK. Analysis of the inhibition of growth produced by canavanine in Escherichia coli. J Bacteriol. 1960;79:794-9.
22. Celis TF, Rosenfeld HJ, Maas WK. Mutant of Escherichia coli K-12 defective in the transport of basic amino acids. J Bacteriol. 1973;116(2):619-26.
23. Celis TF. Independent regulation of transport and biosynthesis of arginine in Escherichia coli K-12. J Bacteriol. 1977;130(3):1244-52.
24. Jeong JY, Yim HS, Ryu JY, Lee HS, Lee JH, Seen DS, et al. One-step sequence- and ligation-independent cloning as a rapid and versatile cloning method for functional genomics studies. Appl Environ Microbiol. 2012;78(15):5440-3.
25. Rajagopal BS, DePonte J,3rd, Tuchman M, Malamy MH. Use of inducible feedback-resistant N-acetylglutamate synthetase (argA) genes for enhanced arginine biosynthesis by genetically engineered Escherichia coli K-12 strains. Appl Environ Microbiol. 1998;64(5):1805-11.
26. Kitagawa M, Ara T, Arifuzzaman M, Ioka-Nakamichi T, Inamoto E, Toyonaga H, et al. Complete set of ORF clones of Escherichia coli ASKA library (a complete set of E. coli K-12 ORF archive): unique resources for biological research. DNA Res. 2005;12(5):291-9.
27. Hagg P, de Pohl JW, Abdulkarim F, Isaksson LA. A host/plasmid system that is not dependent on antibiotics and antibiotic resistance genes for stable plasmid maintenance in Escherichia coli. J Biotechnol. 2004;111(1):17-30.
28. Appleyard RK. Segregation of Lambda Lysogenicity during Bacterial Recombination in Escherichia Coli K12. Genetics. 1954;39(4):429-39.
29. Baba T, Ara T, Hasegawa M, Takai Y, Okumura Y, Baba M, et al. Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol Syst Biol. 2006;2:2006.0008.
30. Bellmann A, Vrljic M, Patek M, Sahm H, Kramer R, Eggeling L. Expression control and specificity of the basic amino acid exporter LysE of Corynebacterium glutamicum. Microbiology. 2001;147(Pt 7):1765-74.
31. Vrljic M, Sahm H, Eggeling L. A new type of transporter with a new type of cellular function: L-lysine export from Corynebacterium glutamicum. Mol Microbiol. 1996;22(5):815-26.
32. Kennerknecht N, Sahm H, Yen MR, Patek M, Saier Jr MH, Jr EL. Export of L-isoleucine from Corynebacterium glutamicum: a two-gene-encoded member of a new translocator family. J Bacteriol. 2002;184(14):3947-56.
33. Simic P, Willuhn J, Sahm H, Eggeling L. Identification of glyA (encoding serine hydroxymethyltransferase) and its use together with the exporter ThrE to increase L-threonine accumulation by Corynebacterium glutamicum. Appl Environ Microbiol. 2002;68(7):3321-7.
34. Morbach S, Sahm H, Eggeling L. l-Isoleucine production with Corynebacterium glutamicum: further Flux increase and limitation of export. Appl Environ Microbiol. 1996;62(12):4345-51.
35. Hua Q, Yang C, Shimizu K. Metabolic control analysis for lysine synthesis using Corynebacterium glutamicum and experimental verification. J Biosci Bioeng. 2000;90(2):184-92.
36. El-Mansi EM, Holms WH. Control of carbon flux to acetate excretion during growth of Escherichia coli in batch and continuous cultures. J Gen Microbiol. 1989;135(11):2875-83.
37. Hollywood N, Doelle HW. Effect of specific growth rate and glucose concentration on growth and glucose metabolism of Escherichia coli K-12. Microbios. 1976;17(67):23-33.
38. Zheng L, Baumann U, Reymond JL. An efficient one-step site-directed and site-saturation mutagenesis protocol. Nucleic Acids Res. 2004;32(14):e115.
39. Link AJ, Phillips D, Church GM. Methods for generating precise deletions and insertions in the genome of wild-type Escherichia coli: application to open reading frame characterization. J Bacteriol. 1997;179(20):6228-37.
40. Binder S, Schendzielorz G, Stabler N, Krumbach K, Hoffmann K, Bott M, et al. A high-throughput approach to identify genomic variants of bacterial metabolite producers at the single-cell level. Genome Biol. 2012;13(5):R40. -2012-13-5-r40.