Memantine plus vitamin d prevents axonal degeneration caused by lysed blood

ACS Chemical Neuroscience

Volumn 6, Issue 3, 2015, Pages 393-397

  Charier, David ^a   Beauchet, Olivier ^b,c,d,e   Bell, Morgane ^f,g   Brugg, Bernard ^f,g   Bartha, Robert ^h   Annweiler, Cedric ^b,c,d,h  

^a UNIVERSITY HOSPITAL OF SAINT ETIENNE   (France)

^b ANGERS UNIVERSITY HOSPITAL   (France)

^c University Memory Clinic   (France)

^d UNIVERSITÉ D'ANGERS   (France)

^e Biomathics   (France)

^f Université Pierre et Marie Curie   (France)

^g SORBONNE UNIVERSITÉ   (France)

^h ROBARTS RESEARCH INSTITUTE   (Canada)

Author keywords

blood; Intracranial hemorrhage; memantine; neuroprotection; vitamin D

Indexed keywords

CALCITRIOL; MEMANTINE; PROTECTIVE AGENT; NEUROPROTECTIVE AGENT; VITAMIN D;

ANIMAL CELL; ARTICLE; BLOOD CLOT LYSIS; BRAIN CELL CULTURE; BRAIN HEMORRHAGE; COMPARATIVE STUDY; DRUG EFFECT; DRUG SCREENING; EMBRYO; HYDROSTATIC PRESSURE; IMMUNOCYTOCHEMISTRY; IN VIVO STUDY; LIMIT OF QUANTITATION; MICROFLUIDICS; MOUSE; NERVE FIBER; NERVE FIBER DEGENERATION; NEUROPROTECTION; NONHUMAN; PHASE CONTRAST MICROSCOPY; PRIORITY JOURNAL; ANIMAL; ANIMAL EMBRYO; BLOOD CELL; BLOOD CLOTTING; BRAIN CORTEX; CELL CULTURE; CELL FRACTIONATION; CYTOLOGY; DRUG EFFECTS; DRUG POTENTIATION; LAB ON A CHIP; NERVE CELL; NERVE DEGENERATION;

ANIMALS; AXONS; BLOOD CELLS; BLOOD COAGULATION; CELL FRACTIONATION; CELLS, CULTURED; CEREBRAL CORTEX; DRUG SYNERGISM; EMBRYO, MAMMALIAN; LAB-ON-A-CHIP DEVICES; MEMANTINE; MICE; NERVE DEGENERATION; NEURONS; NEUROPROTECTIVE AGENTS; VITAMIN D;

EID: 84925104108     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn500303k     Document Type: Article

References (25)

1. Ingall, T., Asplund, K., Mahonen, M., and Bonita, R. (2000) A multinational comparison of subarachnoid hemorrhage epidemiology in the WHO MONICA stroke study Stroke 31, 1054-1061
2. Jaremko, K. M., Chen-Roetling, J., Chen, L., and Regan, R. F. (2010) Accelerated hemolysis and neurotoxicity in neuron-glia-blood clot co-cultures J. Neurochem. 114, 1063-1073
3. Shalak, L. and Perlman, J. M. (2004) Hypoxic-ischemic brain injury in the term infant-current concepts Early Hum. Dev. 80, 125-141
4. Hardingham, G. E. (2009) Coupling of the NMDA receptor to neuroprotective and neurodestructive events Biochem. Soc. Trans. 37, 1147-1160
5. Chipana, C., Camarasa, J., Pubill, D., and Escubedo, E. (2008) Memantine prevents MDMA-induced neurotoxicity Neurotoxicology 29, 179-183
6. Kalueff, A. V. and Tuohimaa, P. (2007) Neurosteroid hormone vitamin D and its utility in clinical nutrition Curr. Opin. Clin. Nutr. Metab. Care. 10, 12-19
7. Annweiler, C., Schott, A. M., Berrut, G., Chauviré, V., Le Gall, D., Inzitari, M., and Beauchet, O. (2010) Vitamin D and ageing: Neurological issues Neuropsychobiology 62, 139-150
8. Annweiler, C. and Beauchet, O. (2012) Possibility of a new anti-alzheimers disease pharmaceutical composition combining memantine and vitamin D Drugs Aging 29, 81-91
9. Annweiler, C., Brugg, B., Peyrin, J. M., Bartha, R., and Beauchet, O. (2014) Combination of memantine and vitamin D prevents axon degeneration induced by amyloid-beta and glutamate Neurobiol. Aging 35, 331-335
10. Kilinc, D., Peyrin, J. M., Soubeyre, V., Magnifico, S., Saias, L., Viovy, J. L., and Brugg, B. (2011) Wallerian-like degeneration of central neurons after synchronized and geometrically registered mass axotomy in a three-compartmental microfluidic chip Neurotox. Res. 19, 149-161
11. Peyrin, J. M., Deleglise, B., Saias, L., Vignes, M., Gougis, P., Magnifico, S., Betuing, S., Pietri, M., Caboche, J., Vanhoutte, P., Viovy, J. L., and Brugg, B. (2011) Axon diodes for the reconstruction of oriented neuronal networks in microfluidic chambers Lab Chip 11, 3663-3673
12. Annweiler, C., Herrmann, F. R., Fantino, B., Brugg, B., and Beauchet, O. (2012) Effectiveness of the combination of memantine plus vitamin D on cognition in patients with Alzheimer disease: A pre-post pilot study Cognit. Behav. Neurol. 25, 121-127
13. Muir, K. W. (2006) Glutamate-based therapeutic approaches: Clinical trials with NMDA antagonists Curr. Opin. Pharmacol. 6, 53-60
14. Bullock, M. R., Merchant, R. E., Carmack, C. A., Doppenberg, E., Shah, A. K., Wilner, K. D., Ko, G., and Williams, S. A. (1999) An open-label study of CP-101,606 in subjects with a severe traumatic head injury or spontaneous intracerebral hemorrhage Ann. N.Y. Acad. Sci. 890, 51-58
15. Annweiler, C., Montero-Odasso, M., Llewellyn, D. J., Richard-Devantoy, S., Duque, G., and Beauchet, O. (2013) Meta-analysis of memory and executive dysfunctions in relation to vitamin D J. Alzheimers Dis. 37, 147-171
16. Littlejohns, T. J., Henley, W. E., Lang, I. A., Annweiler, C., Beauchet, O., Chaves, P. H., Fried, L., Kestenbaum, B. R., Kuller, L. H., Langa, K. M., Lopez, O. L., Kos, K., Soni, M., and Llewellyn, D. J. (2014) Vitamin D and the risk of dementia and Alzheimer disease Neurology 83, 920-928
17. Annweiler, C., Dursun, E., Féron, F., Gezen-Ak, D., Kalueff, A. V., Littlejohns, T., Llewellyn, D. J., Millet, P., Scott, T., Tucker, K. L., Yilmazer, S., and Beauchet, O. (2015) Vitamin D and cognition in older adults: Updated international recommendations J. Int. Med. 277, 45-57
18. Brewer, L. D., Thibault, V., Chen, K. C., Langub, M. C., Landfield, P. W., and Porter, N. M. (2001) Vitamin D hormone confers neuroprotection in parallel with downregulation of L-type calcium channel expression in hippocampal neurons J. Neurosci. 21, 98-108
19. Gezen-Ak, D., Dursun, E., and Yilmazer, S. (2011) The effects of vitamin D receptor silencing on LVSCC-A1C and LVSCC-A1D expressions and NGF release in cortical neurons PLoS One 6, e17553
20. Ibi, M., Sawada, H., Nakanishi, M., Kume, T., Katsuki, H., Kaneko, S., Shimohama, S., and Akaike, A. (2001) Protective effects of 1 alpha,25-(OH)(2)D(3) against the neurotoxicity of glutamate and reactive oxygen species in mesencephalic culture Neuropharmacology 40, 761-771
21. Dursun, E., Gezen-Ak, D., and Yilmazer, S. (2013) A new mechanism for induction of iNOS: Vitamin D-VDR pathway disruption J. Alzheimers Dis. 36, 459-474
22. Moore, M. E., Piazza, A., McCartney, Y., and Lynch, M. A. (2005) Evidence that vitamin D3 reverses age-related inflammatory changes in the rat hippocampus Biochem. Soc. Trans. 33, 573-577
23. Brown, J., Bianco, J. I., McGrath, J. J., and Eyles, D. W. (2003) 1,25-Dihydroxyvitamin D-3 induces nerve growth factor, promotes neurite outgrowth and inhibits mitosis in embryonic rat hippocampal neurons Neurosci. Lett. 343, 139-143
24. Wong, M. S., Delansorne, R., Man, R. Y., Svenningsen, P., and Vanhoutte, P. M. (2010) Chronic treatment with vitamin D lowers arterial blood pressure and reduces endothelium-dependent contractions in the aorta of the spontaneously hypertensive rat Am. J. Physiol.: Heart Circ. Physiol. 299, H1226-234
25. Taylor, A. M., Blurton-Jones, M., Rhee, S. W., Cribbs, D. H., Cotman, C. W., and Jeon, N. L. (2005) A microfluidic culture platform for CNS axonal injury, regeneration and transport Nat. Methods 2, 599-605