Gene expression in transformed lymphocytes reveals variation in endomembrane and HLA pathways modifying cystic fibrosis pulmonary phenotypes

American Journal of Human Genetics

Volumn 96, Issue 2, 2015, Pages 318-328

  O'Neal, Wanda K ^a   Gallins, Paul ^a   Pace, Rhonda G ^a   Dang, Hong ^a   Wolf, Whitney E ^a   Jones, Lisa C ^a   Guo, Xueliang ^a   Zhou, Yi Hui ^b   Madar, Vered ^c   Huang, Jinyan ^d   Liang, Liming ^e   Moffatt, Miriam F ^f   Cutting, Garry R ^g   Drumm, Mitchell L ^h   Rommens, Johanna M ⁱ   Strug, Lisa J ⁱ   Sun, Wei ^a,c   Stonebraker, Jaclyn R ^a   Wright, Fred A ^b   Knowles, Michael R ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c University of North Carolina at Chapel Hill   (United States)

^d SHANGHAI JIAO TONG UNIVERSITY   (China)

^e HARVARD UNIVERSITY   (United States)

^f NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^g JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; HLA ANTIGEN; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; MICRORNA; LPAR6 PROTEIN, HUMAN; LYSOPHOSPHATIDIC ACID RECEPTOR;

ADOLESCENT; ADULT; ANTIGEN PRESENTATION; ARTICLE; CHILD; CHROMOSOME 6P; CYSTIC FIBROSIS; DISEASE SEVERITY; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC CONSERVATION; GENETIC VARIABILITY; HLA SYSTEM; HOMOZYGOTE; HUMAN; LUNG ALVEOLUS MACROPHAGE; LUNG FUNCTION; LYMPHOBLASTOID CELL; LYMPHOCYTE; MALE; MECONIUM ILEUS; NUCLEOTIDE SEQUENCE; ONSET AGE; OXIDATIVE PHOSPHORYLATION; PHENOTYPE; PHENOTYPIC VARIATION; PRIORITY JOURNAL; QUANTITATIVE TRAIT; QUANTITATIVE TRAIT LOCUS; GENE; GENE DELETION; GENE EXPRESSION PROFILING; GENETIC VARIATION; GENETICS; PATHOLOGY; STATISTICAL MODEL;

PSEUDOMONAS AERUGINOSA;

CYSTIC FIBROSIS; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION PROFILING; GENES, MHC CLASS I; GENETIC VARIATION; HUMANS; LINEAR MODELS; PHENOTYPE; RECEPTORS, LYSOPHOSPHATIDIC ACID; SEQUENCE DELETION;

EID: 84925082500     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2014.12.022     Document Type: Article

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