메뉴 건너뛰기




Volumn 372, Issue 12, 2015, Pages 1166-1167

Oral SMAD7 antisense drug for crohn's disease

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; C REACTIVE PROTEIN; CALGRANULIN; INFLIXIMAB; MESSENGER RNA; MONGERSEN; PLACEBO; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA INHIBITOR; VEDOLIZUMAB; GED0301; IMMUNOSUPPRESSIVE AGENT; OLIGONUCLEOTIDE; SMAD7 PROTEIN, HUMAN;

EID: 84925068548     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMe1415053     Document Type: Editorial
Times cited : (14)

References (8)
  • 1
    • 0021756017 scopus 로고
    • Regional ileitis: A pathological and clinical entity. by Burrill B. Crohn, Leon Ginzburg, and Gordon D. Oppenheimer
    • Landmark article Oct 15, 1932
    • Crohn BB, Ginzburg L, Oppenheimer GD. Landmark article Oct 15, 1932. Regional ileitis: a pathological and clinical entity. By Burrill B. Crohn, Leon Ginzburg, and Gordon D. Oppenheimer. JAMA 1984;251:73-9.
    • (1984) JAMA , vol.251 , pp. 73-79
    • Crohn, B.B.1    Ginzburg, L.2    Oppenheimer, G.D.3
  • 2
    • 33845647693 scopus 로고    scopus 로고
    • Inhibition of Smad7 with a specific antisense oligonucleotide facilitates TGFbeta1-mediated suppression of colitis
    • Boirivant M, Pallone F, Di Giacinto C, et al. Inhibition of Smad7 with a specific antisense oligonucleotide facilitates TGFbeta1-mediated suppression of colitis. Gastroenterology 2006; 131:1786-98.
    • (2006) Gastroenterology , vol.131 , pp. 1786-1798
    • Boirivant, M.1    Pallone, F.2    Di Giacinto, C.3
  • 3
    • 84925064199 scopus 로고    scopus 로고
    • Mongersen, an oral SMAD7 antisense oligonucleotide, and Crohn's disease
    • Monteleone G, Neurath MF, Ardizzone S, et al. Mongersen, an oral SMAD7 antisense oligonucleotide, and Crohn's disease. N Engl J Med 2015;372:1104-13.
    • (2015) N Engl J Med , vol.372 , pp. 1104-1113
    • Monteleone, G.1    Neurath, M.F.2    Ardizzone, S.3
  • 4
    • 77950988234 scopus 로고    scopus 로고
    • Infliximab, azathioprine, or combination therapy for Crohn's disease
    • Colombel JF, Sandborn WJ, Reinisch W, et al. Infliximab, azathioprine, or combination therapy for Crohn's disease. N Engl J Med 2010;362:1383-95.
    • (2010) N Engl J Med , vol.362 , pp. 1383-1395
    • Colombel, J.F.1    Sandborn, W.J.2    Reinisch, W.3
  • 5
    • 32044451548 scopus 로고    scopus 로고
    • Human antitumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: The CLASSIC-I trial
    • Hanauer SB, Sandborn WJ, Rutgeerts P, et al. Human antitumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial. Gastroenterology 2006;130: 323-33.
    • (2006) Gastroenterology , vol.130 , pp. 323-333
    • Hanauer, S.B.1    Sandborn, W.J.2    Rutgeerts, P.3
  • 6
    • 84882749768 scopus 로고    scopus 로고
    • Vedolizumab as induction and maintenance therapy for Crohn's disease
    • Sandborn WJ, Feagan BG, Rutgeerts P, et al. Vedolizumab as induction and maintenance therapy for Crohn's disease. N Engl J Med 2013;369:711-21.
    • (2013) N Engl J Med , vol.369 , pp. 711-721
    • Sandborn, W.J.1    Feagan, B.G.2    Rutgeerts, P.3
  • 7
    • 30044449492 scopus 로고    scopus 로고
    • IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis
    • Fichtner-Feigl S, Strober W, Kawakami K, Puri RK, Kitani A. IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis. Nat Med 2006; 12:99-106.
    • (2006) Nat Med , vol.12 , pp. 99-106
    • Fichtner-Feigl, S.1    Strober, W.2    Kawakami, K.3    Puri, R.K.4    Kitani, A.5
  • 8
    • 79959993387 scopus 로고    scopus 로고
    • Transforming growth factor-beta type 1 receptor (ALK5) and Smad proteins mediate TIMP-1 and collagen synthesis in experimental intestinal fibrosis
    • Medina C, Santos-Martinez MJ, Santana A, et al. Transforming growth factor-beta type 1 receptor (ALK5) and Smad proteins mediate TIMP-1 and collagen synthesis in experimental intestinal fibrosis. J Pathol 2011;224:461-72.
    • (2011) J Pathol , vol.224 , pp. 461-472
    • Medina, C.1    Santos-Martinez, M.J.2    Santana, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.