Streptococcus mutans sortase A inhibitory metabolites from the flowers of Sophora japonica

Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 7, 2015, Pages 1394-1397

  Yang, Woo Young ^a   Won, Tae Hyung ^b   Ahn, Chan Hong ^a   Lee, So Hyoung ^a   Yang, Hyeong Cheol ^c   Shin, Jongheon ^b   Oh, Ki Bong ^a  

^a Seoul National University   (South Korea)

^b Seoul National University   (South Korea)

^c School of Dentistry   (South Korea)

Author keywords

Aggregation; Metabolites; Sophora japonica; Sortase A; Streptococcus mutans

Indexed keywords

BACTERIAL ENZYME; CURCUMIN; ENZYME INHIBITOR; FLAVONOID GLYCOSIDE; ISORHAMNETIN 3 O BETA DEXTRO RUTINOSIDE; MALTOL; MALTOL 3 O [4' O 4 COUMAROYL 6' O (3 HYDROXY 3 METHYLGLUTAROYL)] BETA GLUCOPYRANOSIDE; NICOTIFLORIN; SORTASE; SORTASE A; UNCLASSIFIED DRUG; AMINOACYLTRANSFERASE; BACTERIAL PROTEIN; CYSTEINE PROTEINASE; PYRONE DERIVATIVE;

ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DELETION MUTANT; FLOWER; IC50; METABOLITE; NONHUMAN; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOPHORA JAPONICA; STREPTOCOCCUS MUTANS; STRUCTURE ANALYSIS; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CONFORMATION; DOSE RESPONSE; DRUG EFFECTS; GENETICS; GROWTH, DEVELOPMENT AND AGING; ISOLATION AND PURIFICATION; METABOLISM; SOPHORA; STRUCTURE ACTIVITY RELATION;

STREPTOCOCCUS MUTANS; STYPHNOLOBIUM JAPONICUM;

AMINOACYLTRANSFERASES; BACTERIAL PROTEINS; CYSTEINE ENDOPEPTIDASES; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOWERS; MOLECULAR CONFORMATION; PYRONES; SOPHORA; STREPTOCOCCUS MUTANS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84925061503     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2015.02.051     Document Type: Article

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