Remote intrathecal morphine preconditioning confers cardioprotection via spinal cord nitric oxide/cyclic guanosine monophosphate/protein kinase G pathway

Journal of Surgical Research

Volumn 193, Issue 1, 2015, Pages 43-51

  Lu, Yao ^a   Hu, Jun ^a   Zhang, Ye ^a   Dong, Chun Shan ^a   Wong, Gordon Tin Chun ^b  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Morphine; Myocardial reperfusion injury; Nitric oxide; Remote preconditioning; Spinal cord

Indexed keywords

CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; MORPHINE; NITRIC OXIDE; CARDIOTONIC AGENT; INDUCIBLE NITRIC OXIDE SYNTHASE; NARCOTIC ANALGESIC AGENT; NOS2 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLORIMETRY; CONTROLLED STUDY; CROSS REACTION; HEART LEFT VENTRICLE; HEART PROTECTION; HEART VENTRICLE FIBRILLATION; IMMUNOHISTOCHEMISTRY; ISCHEMIC PRECONDITIONING; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REMOTE INTRATHECAL MORPHINE PRECONDITIONING; REPERFUSION; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINAL CORD DORSAL HORN; THORACIC SPINAL CORD; ANIMAL; DRUG EFFECTS; ENZYMOLOGY; GENETICS; HEART INFARCTION PREVENTION; HEMODYNAMICS; INTRASPINAL DRUG ADMINISTRATION; METABOLISM; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; SIGNAL TRANSDUCTION; SPINAL CORD; SPRAGUE DAWLEY RAT;

ANALGESICS, OPIOID; ANIMALS; CARDIOTONIC AGENTS; CYCLIC GMP; CYCLIC GMP-DEPENDENT PROTEIN KINASES; HEMODYNAMICS; INJECTIONS, SPINAL; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MALE; MORPHINE; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SPINAL CORD;

EID: 84925023116     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2014.08.014     Document Type: Article

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