Role of glycosyltransferase PomGnT1 in glioblastoma progression

Neuro-Oncology

Volumn 17, Issue 2, 2015, Pages 211-222

  Lan, Jin ^a   Guo, Pin ^a   Lin, Yingying ^a   Mao, Qing ^a   Guo, Liemei ^a   Ge, Jianwei ^a   Li, Xiaoxiong ^a   Jiang, Jiyao ^a   Lin, Xinjian ^a,c   Qiu, Yongming ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Shanghai Institute of Digestive Disease   (China)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

glioblastoma; PomGnT1; prognosis; progression

Indexed keywords

BETA CATENIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GLYCOSYLTRANSFERASE; MITOGEN ACTIVATED PROTEIN KINASE; PEPTIDE O LINKED MANNOSE BETA 1,2 N ACETYLGLUCOSAMINYLTRANSFERASE 1; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE BETA; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; N ACETYLGLUCOSAMINYLTRANSFERASE; PROTEIN O-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE; RECEPTOR LIKE PROTEIN TYROSINE PHOSPHATASE;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER PROGNOSIS; CELL ADHESION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SURVIVAL TIME; TUMOR GROWTH; TUMOR INVASION; ANIMAL; BRAIN NEOPLASMS; DISEASE COURSE; METABOLISM; MIDDLE AGED; NUDE MOUSE; PROGNOSIS; SIGNAL TRANSDUCTION; SURVIVAL RATE; TUMOR CELL LINE; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; BETA CATENIN; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; DISEASE PROGRESSION; FEMALE; GLIOBLASTOMA; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, NUDE; MIDDLE AGED; N-ACETYLGLUCOSAMINYLTRANSFERASES; NEOPLASM INVASIVENESS; PROGNOSIS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 5; SURVIVAL RATE;

EID: 84924995913     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/nou151     Document Type: Article

References (36)

1. Goodenberger ML, Jenkins RB. Genetics of adult glioma. Cancer Genet. 2012;205(12):613-621.
2. Wen PY, Kesari S. Malignant gliomas in adults. N Engl J Med. 2008; 359(5):492-507.
3. Sawyers CL. The cancer biomarker problem. Nature. 2008; 452(7187):548-552.
4. Sayegh ET, Kaur G, Bloch O, et al. Systematic review of protein biomarkers of invasive behavior in glioblastoma. Molec Neurobiol. 2013;49(3):1212-1244.
5. Stupp R, Hegi ME, Neyns B, et al. Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma. J Clin Oncol. 2010;28(16): 2712-2718.
6. Levin VA, Phuphanich S, Yung WK, et al. Randomized, double-blind, placebo-controlled trial of marimastat in glioblastoma multiforme patients following surgery and irradiation. J Neurooncol. 2006; 78(3):295-302.
7. Abbott KL, Troupe K, Lee I, et al. Integrin-dependent neuroblastoma cell adhesion and migration on laminin is regulated by expression levels of two enzymes in the O-mannosyl-linked glycosylation pathway, PomGnT1 and GnT-Vb. Exp Cell Res. 2006;312(15):2837-2850.
8. Yoshida A, Kobayashi K, Manya H, et al. Muscular dystrophy and neuronal migration disorder caused by mutations in a glycosyltransferase, POMGnT1. Dev Cell. 2001;1(5):717-724.
9. Beltran-Valero de Bernabe D, Currier S, Steinbrecher A, et al. Mutations in the O-mannosyltransferase gene POMT1 give rise to the severe neuronal migration disorder Walker-Warburg syndrome. Am J Hum Genet. 2002;71(5):1033-1043.
10. Kobayashi K, Nakahori Y, Miyake M, et al. An ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophy. Nature. 1998;394(6691):388-392.
11. Endo T. O-mannosyl glycans in mammals. Biochim Biophys Acta. 1999;1473(1):237-246.
12. Lan J, Guo P, Chen M, et al. O-linked mannose beta-1, 2-N-acetylglucosaminyltransferase 1 correlated with the malignancy in glioma. J Craniofac Surg. 2013;24(4):1441-1446.
13. Bredel M, Scholtens DM, Yadav AK, et al. NFKBIA deletion in glioblastomas. N Engl J Med. 2011;364(7):627-637.
14. Catzavelos C, Bhattacharya N, Ung YC, et al. Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer. Nat Med. 1997;3(2):227-230.
15. van Diest PJ, van Dam P, Henzen-Logmans SC, et al. A scoring system for immunohistochemical staining: consensus report of the task force for basic research of the EORTC-GCCG. European Organisation for Research and Treatment of Cancer-Gynaecological Cancer Cooperative Group. J Clin Pathol. 1997; 50(10):801-804.
16. Wu ZB, Cai L, Lin SJ, et al. High-mobility group box 2 is associated with prognosis of glioblastoma by promoting cell viability, invasion, and chemotherapeutic resistance. Neuro Oncol. 2013; 15(9):1264-1275.
17. Shang X, Lin X, Alvarez E, et al. Tight junction proteins claudin-3 and claudin-4 control tumor growth and metastases. Neoplasia. 2012;14(10):974-985.
18. Shen Y, Wang Y, Sheng K, et al. Serine/threonine protein phosphatase 6 modulates the radiation sensitivity of glioblastoma. Cell Death Dis. 2011;2:e241.
19. Fan QW, Cheng CK, Gustafson WC, et al. EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma. Cancer Cell. 2013;24(4):438-449.
20. Ying WZ, Zhang HG, Sanders PW. EGF receptor activity modulates apoptosis induced by inhibition of the proteasome of vascular smooth muscle cells. J Am Soc Nephrol. 2007;18(1):131-142.
21. Sloss CM, Wang F, Liu R, et al. Proteasome inhibition activates epidermal growth factor receptor (EGFR) and EGFR-independent mitogenic kinase signaling pathways in pancreatic cancer cells. Clin Cancer Res. 2008;14(16):5116-5123.
22. Sloss CM, Wang F, Palladino MA, et al. Activation of EGFR by proteasome inhibition requires HB-EGF in pancreatic cancer cells. Oncogene. 2010;29(21):3146-3152.
23. Abbott KL, Matthews RT, Pierce M. Receptor tyrosine phosphatase beta (RPTPbeta) activity and signaling are attenuated by glycosylation and subsequent cell surface galectin-1 binding. J Biol Chem. 2008;283(48):33026-33035.
24. Simoneau M, Coulombe G, Vandal G, et al. SHP-1 inhibits beta-catenin function by inducing its degradation and interfering with its association with TATA-binding protein. Cell Signal. 2011;23(1):269-279.
25. Yang W, Xia Y, Ji H, et al. Nuclear PKM2 regulates beta-catenin transactivation upon EGFR activation. Nature. 2011;480(7375): 118-122.
26. Homma T, Fukushima T, Vaccarella S, et al. Correlation among pathology, genotype, and patient outcomes in glioblastoma. J Neuropathol Exp Neurol. 2006;65(9):846-854.
27. Bigner SH, Wong AJ, Mark J, et al. Relationship between gene amplification and chromosomal deviations in malignant human gliomas. Cancer Genet Cytogenet. 1987;29(1):165-170.
28. Liu J, Ball SL, Yang Y, et al. A genetic model for muscle-eye-brain disease in mice lacking protein O-mannose 1, 2-N-acetylglucosaminyltransferase (POMGnT1). Mech Dev. 2006; 123(3):228-240.
29. Reddy KB, Nabha SM, Atanaskova N. Role of MAP kinase in tumor progression and invasion. Cancer Metastasis Rev. 2003;22(4): 395-403.
30. She QB, Solit DB, Ye Q, et al. The BAD protein integrates survival signaling by EGFR/MAPK and PI3 K/Akt kinase pathways in PTEN-deficient tumor cells. Cancer Cell. 2005;8(4):287-297.
31. McNamara MG, Sahebjam S, Mason WP. Emerging biomarkers in glioblastoma. Cancers. 2013;5(3):1103-1119.
32. Wu YM, Liu CH, Hu RH, et al. Mucin glycosylating enzyme GALNT2 regulates the malignant character of hepatocellular carcinoma by modifying the EGF receptor. Cancer Res. 2011;71(23):7270-7279.
33. Gabius HJ, van de Wouwer M, Andre S, et al. Down-regulation of the epidermal growth factor receptor by altering N-glycosylation: emerging role of beta1, 4-galactosyltransferases. Anticancer Res. 2012;32(5): 1565-1572.
34. Liu J, Liu H, Zhang W, et al. N-acetylglucosaminyltransferase V confers hepatoma cells with resistance to anoikis through EGFR/PAK1 activation. Glycobiol. 2013;23(9):1097-1109.
35. Dube DH, Bertozzi CR. Glycans in cancer and inflammation-potential for therapeutics and diagnostics. Nat Rev Drug Discov. 2005;4(6):477-488.
36. Wang C, Yang Y, Yang Z, et al. EGF-mediated migration signaling activated by N-acetylglucosaminyltransferase-V via receptor protein tyrosine phosphatase kappa. Arch Biochem Biophys. 2009;486(1):64-72.