Extracellular vesicle-derived CD14 is independently associated with the extent of cardiovascular disease burden in patients with manifest vascular disease

European Journal of Preventive Cardiology

Volumn 22, Issue 4, 2015, Pages 451-457

  Vrijenhoek, Joyce EP ^a,b   Pasterkamp, Gerard ^a   Moll, Frans L ^a   De Borst, Gert Jan ^a   Bots, Michiel L ^a   Catanzariti, Louise ^a   Van De Weg, Sander M ^a   De Kleijn, Dominique P V ^a,b,c   Visseren, Frank LJ ^a   Ruijter, Hester M Den ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

^c NATIONAL UNIVERSITY HOSPITAL   (Singapore)

Author keywords

Atherosclerosis; biomarkers; peripheral vascular diseases; protein

Indexed keywords

ALPHA 2 ANTIPLASMIN; CD14 ANTIGEN; CYSTATIN C; BIOLOGICAL MARKER; CST3 PROTEIN, HUMAN;

ABDOMINAL AORTA ANEURYSM; ADULT; ANKLE BRACHIAL INDEX; AORTA; ARTERIAL WALL THICKNESS; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR PARAMETERS; CARDIOVASCULAR RISK; CAROTID ARTERY OBSTRUCTION; CELL VACUOLE; CEREBROVASCULAR DISEASE; CORONARY ARTERY DISEASE; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; ECHOGRAPHY; EXTRACELLULAR SPACE; EXTRACELLULAR VESICLE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PRIORITY JOURNAL; AGED; BLOOD; CARDIOVASCULAR DISEASES; CHEMISTRY; EXOSOME; MIDDLE AGED; MULTIVARIATE ANALYSIS; ODDS RATIO; PREDICTIVE VALUE; RISK FACTOR; SEVERITY OF ILLNESS INDEX; STATISTICAL MODEL;

AGED; ALPHA-2-ANTIPLASMIN; ANTIGENS, CD14; BIOMARKERS; CARDIOVASCULAR DISEASES; CROSS-SECTIONAL STUDIES; CYSTATIN C; EXTRACELLULAR VESICLES; FEMALE; HUMANS; LINEAR MODELS; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; ODDS RATIO; PREDICTIVE VALUE OF TESTS; RISK FACTORS; SEVERITY OF ILLNESS INDEX;

EID: 84924968679     PISSN: 20474873     EISSN: 20474881     Source Type: Journal    
DOI: 10.1177/2047487313518478     Document Type: Article

References (22)

1. Vanwijk MJ, Vanbavel E, Sturk A, et al. Microparticles in cardiovascular diseases. Cardiovas Res. 2003 ; 59: 277-287
2. Théry C, Ostrowski M, Segura E. Membrane vesicles as conveyors of immune responses. Nat Rev Immunol. 2009 ; 9: 581-593
3. Mause SF, Weber C. Microparticles: protagonists of a novel communication network for intercellular information exchange. Circ Res. 2010 ; 107: 1047-1057
4. Rautou P, Vion A, Amabile N, et al. Microparticles, vascular function, and atherothrombosis. Circ Res. 2011 ; 109: 593-606
5. Mallat Z, Benamer H, Hugel B, et al. Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes. Circulation. 2000 ; 101: 841-843
6. Chironi G, Simon A, Hugel B, et al. Circulating leukocyte-derived microparticles predict subclinical atherosclerosis burden in asymptomatic subjects. Arterioscler Thromb Vasc Biol. 2006 ; 26: 2775-2780
7. Yong PJA, Koh CH, Shim WSN. Endothelial microparticles: missing link in endothelial dysfunction?. Eur J Prev Cardiol. 2013 ; 20: 496-512
8. Nozaki T, Sugiyama S, Sugamura K, et al. Prognostic value of endothelial microparticles in patients with heart failure. Eur J Heart Fail. 2010 ; 12: 1223-1228
9. Montoro-García S, Shantsila E, Tapp LD, et al. Small-size circulating microparticles in acute coronary syndromes: relevance to fibrinolytic status, reparative markers and outcomes. Atherosclerosis. 2013 ; 227: 313-322
10. De Hoog VC, Timmers L, Schoneveld AH, et al. Serum extracellular vesicle protein levels are associated with acute coronary syndrome. Eur Heart J Acute Card Care. 2012 ; 2: 53-60
11. Kanhai DA, Visseren FLJ, van der Graaf Y, et al. Microvesicle protein levels are associated with increased risk for future vascular events and mortality in patients with clinically manifest vascular disease. Int J Card. 2013 ; 168: 2358-2363
12. Simons PC, Algra A, Van de Laak MF, et al. Second manifestations of ARTerial disease (SMART) study: rationale and design. Eur J Epidemiol. 1999 ; 15: 773-781
13. Aboyans V, Criqui MH, Abraham P, et al. Measurement and interpretation of the ankle-brachial index: a scientific statement from the American Heart Association. Circulation. 2012 ; 126: 2890-2909
14. Stein JH, Korcarz CE, Hurst RT, et al. Use of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovascular disease risk: a consensus statement from the American Society of Echocardiography Carotid Intima-Media Thickness Task Force. Endorsed by the Society for Vascula. J Am Soc Echocardiogr. 2008 ; 21: 93-111
15. El Andaloussi S, Mager I, Breakefield XO, et al. Extracellular vesicles: biology and emerging therapeutic options. Nat Rev Drug Discov. 2013 ; 12: 347-357
16. Shlipak MG, Sarnak MJ, Katz R, et al. Cystatin C and the risk of death and cardiovascular events among elderly persons. N Engl J Med. 2005 ; 352: 2049-2060
17. Lijnen HR, Okada K, Matsuo O, et al. α2-Antiplasmin gene deficiency in mice is associated with enhanced fibrinolytic potential without overt bleeding. Blood. 1999 ; 93: 2274-2281
18. Essayagh S, Xuereb J, Terrisse A, et al. Microparticles from apoptotic monocytes induce transient platelet recruitment and tissue factor expression by cultured human vascular endothelial cell via a redox-sensitive mechanism. Thromb Haemost. 2007 ; 98: 831-837
19. Aharon A, Tamari T, Brenner B. Monocyte-derived microparticles and exosomes induce procoagulant and apoptotic effects on endothelial cells. Thromb Haemost. 2008 ; 100: 878-885
20. Palmerini T, Coller BS, Cervi V, et al. Monocyte-derived tissue factor contributes to stent thrombosis in an in vitro system. J Am Coll Card. 2004 ; 44: 1570-1577
21. Leatham EW, Bath PMW, Tooze A. Increased monocyte tissue factor expression in coronary disease. Br Heart J. 1995 ; 73: 10-13
22. Pasterkamp G, de Kleijn D. Microparticles, debris that hurts. J Am Coll Cardiol. 2008 ; 52: 1312-1313