Microparticles, Debris That Hurts

Journal of the American College of Cardiology

Volumn 52, Issue 16, 2008, Pages 1312-1313

  Pasterkamp, Gerard ^a   de Kleijn, Dominique ^b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

Author keywords

atherosclerosis; CD40 ligand; endothelial proliferation; microparticles; neovessel

Indexed keywords

CD40 LIGAND;

APOPTOSIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BLOOD VESSEL WALL; CELL MEMBRANE; CELL PROLIFERATION; DISEASE COURSE; EDITORIAL; ENDOTHELIUM CELL; HUMAN; INFLAMMATION; MACROPHAGE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; THROMBOCYTE;

APOPTOSIS; CAROTID ARTERY DISEASES; CAROTID STENOSIS; CD40 LIGAND; CELL PROLIFERATION; FEMALE; HUMANS; MALE; NEOVASCULARIZATION, PATHOLOGIC; PARTICLE SIZE; RISK FACTORS; SENSITIVITY AND SPECIFICITY;

EID: 53049102904     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2008.07.038     Document Type: Editorial

References (13)

1. Morel O., Toti F., Hugel B., et al. Procoagulant MPs. Arterioscl Thromb Vasc Biol 26 (2006) 2594-2604
2. Zakharova L., Svetlova M., and Fomina A.F. T cell exosomes induce cholesterol accumulation in human monocytes via phosphatidylserine receptor. J Cell Physiol 212 (2007) 174-181
3. Tan K.T., Tayebjee M.H., Lim H.S., and Lip G.Y. Clinically apparent atherosclerotic disease in diabetes is associated with an increase in platelet microparticle levels. Diabet Med 22 (2005) 1657-1662
4. Chironi G., Simon A., Hugel B., et al. Circulating leucocyte-derived microparticles predict subclinical atherosclerosis burden in asymptomatic subjects. Arterioscl Thromb Vasc Biol 26 (2006) 2775-2780
5. Key N. Platelet tissue factor: how did it get there and is it important?. Semin Hematol 45 (2008) S16-S20
6. Canault M., Leroyer A.S., Peiretti F., et al. MPs of human atherosclerotic plaques enhance the shedding of the tumor necrosis factor-alpha converting enzyme/ADAM17 substrates, tumor necrosis factor and tumor necrosis factor receptor-1. Am J Pathol 171 (2007) 1713-1723
7. Leroyer A.S., Rautou P.-E., Silvestre J.-S., et al. CD40 ligand+ microparticles from human atherosclerotic plaques stimulate endothelial proliferation and angiogenesis: a potential mechanism for intraplaque neovascularization. J Am Coll Cardiol 52 (2008) 1302-1311
8. Brill A., Dashevsky O., Rivo J., Gozal Y., and Varon D. Platelet-derived microparticles induce angiogenesis and stimulate post-ischemic revascularisation. Cardiovasc Res 67 (2005) 30-38
9. Lutgens E., Gorelik L., Daemen M.J., et al. Requirement for CD154 in the progression of atherosclerosis. Nat Med 11 (1999) 1313-1316
10. Mach F., Schönbeck U., Sukhova G.K., Atkinson E., and Libby P. Reduction of atherosclerosis in mice by inhibition of CD40 signalling. Nature 394 (1998) 200-203
11. Santilli F., Basili S., Ferroni P., and Davi G. CD40/CD40L system and vascular disease. Intern Emerg Med 2 (2007) 256-268
12. Mirabet M., Barrabés J.A., Quiroga A., and Garcia-Dorado D. Platelet pro-aggregatory effects of CD40L monoclonal antibody. Mol Immunol 45 (2008) 937-944
13. Azevedo L.C., Pedro M.A., and Laurindo F.R. Circulating microparticles as therapeutic targets in cardiovascular disease. Recent Patents Cardiovasc Drug Discov 2 (2007) 41-51