Correlating Minimum Inhibitory Concentrations of ofloxacin and moxifloxacin with gyrA mutations using the genotype MTBDRsl assay

Tuberculosis

Volumn 95, Issue 2, 2015, Pages 137-141

  Kambli, Priti ^a   Ajbani, Kanchan ^a   Sadani, Meeta ^a   Nikam, Chaitali ^a   Shetty, Anjali ^a   Udwadia, Zarir ^a   Rodwell, Timothy C ^b   Catanzaro, Antonino ^b   Rodrigues, Camilla ^a  

^a P D HINDUJA NATIONAL HOSPITAL   (India)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Drug susceptibility testing; Fluoroquinolones; Level of resistance; Mutations

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING) A; MOXIFLOXACIN; OFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING); QUINOLONE DERIVATIVE; TUBERCULOSTATIC AGENT;

ARTICLE; ASSAY; BACTERIUM ISOLATE; GENE MUTATION; GENOTYPE MTBDRSL ASSAY; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; ANTIBIOTIC RESISTANCE; DOSE RESPONSE; DRUG EFFECTS; GENETICS; GENOTYPE; HUMAN; MICROBIAL SENSITIVITY TEST; MULTIDRUG RESISTANCE; MUTATION; PROCEDURES;

ANTITUBERCULAR AGENTS; DNA GYRASE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, BACTERIAL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; FLUOROQUINOLONES; GENOTYPE; HUMANS; MICROBIAL SENSITIVITY TESTS; MUTATION; MYCOBACTERIUM TUBERCULOSIS; OFLOXACIN;

EID: 84924968523     PISSN: 14729792     EISSN: 1873281X     Source Type: Journal    
DOI: 10.1016/j.tube.2014.11.003     Document Type: Article

References (24)

1. World Health Organization (WHO) Global tuberculosis control: WHO report 2012 2012 World Health Organization WHO/HTM/TB/2012.6
2. K. Ajbani, A. Shetty, A. Mehta, and C. Rodrigues Rapid diagnosis of extensively drug-resistannt tuberculosis by use of a reverse line blot hybridization assay J Clin Microbiol 49 2011 2546 2551
3. Z. Udwadia, R. Amale, K. Ajbani, and C. Rodrigues Totally drug resistance tuberculosis in India Clin Infect Dis 54 2012 579 581
4. A. Krüüner, M. Yates, and F. Drobniewski Evaluation of MGIT 960-based antimicrobial testing and determination of critical concentrations of first- and second-line antimicrobial drugs with drug-resistant clinical isolates of Mycobacterium tuberculosis J Clin Microbiol 44 2006 811 818
5. S. Kim Drug -Susceptibility testing in tuberculosis: methods and reliability of results Eur Respir J 25 2005 564 569
6. E. Nosova, A. Bukatina, and Y. Isaeva Analysis of mutations in the gyrA and gyrB genes and their association with the resistance of Mycobacterium tuberculosis to levofloxacin, moxifloxacin and gatifloxacin J Med Microbiol 62 2013 108 113
7. M. Barnard, L. Parsons, P. Miotto, D. Cirillo, K. Feldmann, C. Gutierrez, and A. Somoskovi Molecular detection of drug- resistant tuberculosis by line probe assay FIND 2012 1 229
8. H. Leonid, and G. Cangelosi Drug resistance assays for mycobacterium tuberculosis [chapter 81] Douglas Mayers, Antimicrobial drug resistance 2009 1161 1170
9. Genotype MTBDRplus VER 2.0, Molecular genetic assay for identification of the M. tuberculosis complex and is resistance to rifampicin and isoniazid from clinical specimens and cultivated samples. Hain Lifescience. IFU-304A-02.
10. B. Springer, K. Lucke, R. Maibach, C. Ritter, and E. Bottger Quantitative drug susceptibility testing of mycobacterium tuberculosis by use of MGIT 960 and epicenter instrumentation J Clin Microbiol 47 2009 1773 1780
11. E. Bottger The ins and outs of Mycobacterium tuberculosis drug susceptibility testing Clin Microbiol Infect 17 2011 1128 1134
12. A. Kolyva, and P. Karakousis Old and new TB drugs: mechanisms of action and resistance [chapter 9] Pere-joan Cardona, Understanding tuberculosis - new approaches to fighting against drug resistance 2012 209 232 10.5772/30992
13. A. Groll, A. Martin, P. Jureen, S. Hoffner, P. vandamme, F. Portaels, J. Palomino, and P. silva Fluoroquinolone resistance in mycobacterium tuberculosis and mutations in gyrA and gyrB Antimicrob Agents Chemother 53 2009 4498 4500
14. J. Poissy, A. Aubry, and C. Fernandez Should moxifloxacin be used for the treatment of extensively drug-resistant tuberculosis? an answer from a murine model Antimicrob Agents Chemother 54 2010 4765 4771
15. F. Maruri, T. Sterling, A. Kaiga, A. Blackman, Y. Heijden, C. Mayer, E. Cambau, and A. Aubry A systematic review of gyrasemuationns associated with fluoroquinolones - resistant Mycobacterium tuberculosis and a proposed gyrase numbering system J Antimicrob Chemother 67 2012 819 831
16. A. Ginsburg, J. Grosset, and W. Bishai Fluoroquinolones, tuberculosis and resistance Lancet Infect Dis 3 2003 432 442
17. K. Angeby, P. Jureen, C. Giske, E. Chryssanthou, E. Sturegard, M. Nordvall, A. Johansson, J. Werngren, G. Kahlmeter, S. Hoffner, and T. Schon Wild-type MIC disributions of four fluoroquinolones active against mycobacterium tuberculosis in relation to current critical concentrations and available pharmacokinetic and pharmacodynamics data J Antimicrob Chemother 65 2012 946 952
18. F. Sirgel, R. Warren, E. Steicher, T. Victor, P. Helden, and E. Bottger gyrA mutations and phenotypic susceptibility levels to ofloxacin and moxifloxacin in clinical isolates of Mycobacterium tuberculosis J Antimicrob Chemother 67 5 2012 1088 1093
19. D. Almeida, C. Rodrigues, Z. Udwadia, A. Lalvani, G. Gothi, P. Mehta, and A. Mehta Incidence of multidrug-resistant tuberculosis in urban and rural India and implications for prevention Clin Infect Dis 36 2003 152 154
20. S. GraceLin, E. Desmond, D. Bonato, W. Gross, and S. Siddiqi Multicenter evaluation of bactec MGIT 960 system for second-line drug susceptibility testing of Mycobacterium tuberculosis complex J Clin Microbiol 47 2009 3630 3634
21. Policy guidance on drug susceptibility testing (DST) of second line antituberculosis drugs 2008 World Health Organization (WHO) (WHO/HTN/TB/2008.392)
22. K. Ajbani, C. Nikam, M. Kazi, C. Gray, C. Boehme, K. Balan, A. Shetty, and C. Rodrigues Evaluation of genotype MTBDRsl assay to detect drug resistance associated with fluoroquinolones,aminoglycosides and ethambutol on clinical sediments PLoS One 7 2012 1 6 10.1371/journal.pone.004943
23. S. Lin, T. Rodwell, T. Rider, L. Rider, L. Pham, A. Catanzaro, and E. Desmond Pyrosequencing for rapid detection of extensively resistant Mycobacterium tuberculosis in clinical isolates J Clin Microbiol 52 2 2014 475 482
24. L. Jing, X. Gao, L. Tao, W. Jie, S. Gang, L. Qingyun, J. Yuan, Z. Yangyi, M. Jian, and G. Qian Association of gyrA/B mutations and resistance levels to fluoroquinolones in clinical isolates of Mycobacterium tuberculosis Emerg Microbes Infect 3 2014 1 5 10.1038/emi.2014.21